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Risk factors across the life course and dementia in a Brazilian population: results from the Sao Paulo Ageing & Health Study (SPAH)

SCAZUFCA, Marcia; MENEZES, Paulo R.; ARAYA, Ricardo; RIENZO, Vanessa D. Di; ALMEIDA, Osvaldo P.; GUNNELL, David; LAWLOR, Debbie A.
Fonte: OXFORD UNIV PRESS Publicador: OXFORD UNIV PRESS
Tipo: Artigo de Revista Científica
ENG
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Background Several mechanisms have been suggested to explain the association between adversities across life and dementia. This study aimed to investigate the association between indicators of socioeconomic disadvantages throughout the life-course and dementia among older adults in Sao Paulo, Brazil and to explore possible causal pathways. Methods We used baseline data from the SPAH study which involved participants aged 65 years and older (n = 2005). The outcome of interest was prevalent dementia. Exposures included in the analyses were socioeconomic position (SEP) indicators in childhood (place of birth and literacy) and adulthood (occupation and income), anthropometric measurements as markers of intrauterine and childhood environment (head circumference and leg length), smoking, diabetes and hypertension. Logistic regression models were used to test the hypothesized pathways and to assess whether there was an association between cumulative adversities across the life course and prevalent dementia. Results Indicators of socioeconomic disadvantage in early life were associated with increased prevalence of dementia. This association was partially mediated through adulthood SEP. Head circumference and leg length were also clearly associated with dementia but there was no evidence that this association was mediated by early life socioeconomic disadvantage. There was an association between cumulative unfavourable conditions across the life course and dementia. Conclusions Early life disadvantages seem to operate through biological mechanisms associated with passive brain reserve and opportunities in life representing active cognitive reserve. Prevention of dementia should start early in life and continue through life span as seen with many other chronic diseases.

Antropometria e biomecânica comparativa da locomoção de corredores com e sem desigualdade estrutural de comprimento de membros inferiores; Comparative anthropometry and biomechanics of locomotion in runners with and without structural leg length discrepancy

Pereira, Carla Sonsino
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 25/09/2006 PT
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Existe uma alta incidência de desigualdade de membros inferiores na população geral, podendo ser do tipo estrutural, onde existe diferença no comprimento de estruturas ósseas, ou funcional, como resultado de alterações mecânicas dos membros inferiores (MMII). A desigualdade pode ainda ser classificada quanto a sua magnitude, sendo discreta, moderada, ou grave. São muitos os métodos antropométricos utilizados para avaliar a desigualdade, entre os mais usados estão os métodos clínicos, como o uso de fita métrica para medir a distância entre duas saliências ósseas. Além destes, os métodos radiográficos também podem ser usados, porém com menor freqüência devido ao custo elevado e exposição à radiação. As desigualdades discretas têm sido associadas especificamente à fratura por estresse, dor lombar e osteoartrite. Quando uma desigualdade está presente em indivíduos cuja sobrecarga mecânica é acentuada pela sua prática profissional, diária ou recreativa, estas desordens podem se manifestar precoce e gravemente. O objetivo deste estudo foi comparar diversas medidas antropométricas de comprimento de MMII usadas na prática clínica com a escanometria em corredores, e estudar a Força Reação do Solo durante a marcha e a corrida de corredores com desigualdade estrutural discreta de membros inferiores. Observou-se que a presença de desigualdade de membros inferiores foi associada à maior incidência de sintomas nos quadris e joelhos nos corredores. As medidas clínicas EIAS/MM (R=0...

Impact of leg length and body mass on the stride length and gait speed of infants with normal motor development: A longitudinal study

Rodriguez,Emmanuelle B.; Chagas,Paula S. C.; Silva,Paula L. P.; Kirkwood,Renata N.; Mancini,Marisa C.
Fonte: Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia Publicador: Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/04/2013 EN
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BACKGROUND: Gait acquisition is supported by changes in the neuromusculoskeletal system of the child. Changes in the dimensions of the body structures resulting from the growth of the child partly explain gait improvement in the first year of life. OBJECTIVES: To evaluate whether changes in body mass and leg length modulate the effect of independent gait practice (experience) on gait speed and stride length. METHOD: Thirty-two infants with normal development were monitored monthly from the acquisition of independent gait until six months post-acquisition. Longitudinal evaluations included measurements of the body mass and leg length of each child. Temporospatial variables of gait (speed and stride length) were documented using the Qualisys Pro-reflex(r) system. The data were analyzed using multilevel regression models, with a significance level of α=0.05. RESULTS: An effect of the practice time on speed (p<0.0001) and stride length (p<0.0001) was observed. The change in leg length had a marginal effect on the rate of gait speed change: children whose leg growth was faster showed a higher rate of speed change (p=0.07). No other effects of anthropometric parameters were observed. CONCLUSIONS: The results suggest that the practice time promotes the improvement of the gait pattern of infants in the first year of life. However...

Precise tuning of barnacle leg length to coastal wave action.

Arsenault, D. J.; Marchinko, K. B.; Palmer, A. R.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em 22/10/2001 EN
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Both spatial and temporal variation in environmental conditions can favour intraspecific plasticity in animal form. But how precise is such environmental modulation? Individual Balanus glandula Darwin, a common northeastern Pacific barnacle, produce longer feeding legs in still water than in moving water. We report here that, on the west coast of Vancouver Island, Canada, the magnitude and the precision of this phenotypic variation is impressive. First, the feeding legs of barnacles from protected bays were nearly twice as long (for the same body mass) as those from open ocean shores. Second, leg length varied surprisingly precisely with wave exposure: the average maximum velocities of breaking waves recorded in situ explained 95.6-99.5% of the variation in average leg length observed over a threefold range of wave exposure. The decline in leg length with increasing wave action was less than predicted due to simple scaling, perhaps due to changes in leg shape or material properties. Nonetheless, the precision of this relationship reveals a remarkably close coupling between growth environment and adult form, and suggests that between-population differences in barnacle leg length may be used for estimating differences in average wave exposure easily and accurately in studies of coastal ecology.

Biomechanical implications of mild leg length inequality.

McCaw, S T; Bates, B T
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /03/1991 EN
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The effect of mild leg length inequality (lower extremity length difference less than 3 cm) on posture and gait has been the source of much controversy. Many opinions have been expressed both for and against the need for intervention to reduce the magnitude of the discrepancy. This paper emphasizes the need for accurate and reliable assessment of leg length differences using a clinically functional radiographic technique, and reviews the biomechanical implications of leg length inequality as related to the development of stress fractures, low back pain and osteoarthritis.

Leg length, insulin resistance, and coronary heart disease risk: The Caerphilly Study

Davey, S; Greenwood, R; Gunnell, D; Sweetnam, P; Yarnell, J; Elwood, P
Fonte: BMJ Group Publicador: BMJ Group
Tipo: Artigo de Revista Científica
Publicado em /12/2001 EN
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BACKGROUND—Adult height has been inversely associated with coronary heart disease risk in several studies. The mechanism for this association is not well understood, however, and this was investigated by examining components of stature, cardiovascular disease risk factors and subsequent coronary heart disease in a prospective study.
METHODS—All men aged 45-59 years living in the town of Caerphilly, South Wales were approached, and 2512 (89%) responded and underwent a detailed examination, which included measurement of height and sitting height (from which an estimate of leg length was derived). Participants were followed up through repeat examinations and the cumulative incidence of coronary heart disease—both fatal and non-fatal—over a 15 year follow up period is the end point in this report.
RESULTS—Cross sectional associations between cardiovascular risk factors and components of stature (total height, leg length and trunk length) demonstrated that factors related to the insulin resistance syndrome—the homeostasis model assessment of insulin resistance, fasting triglyceride levels and total to HDL cholesterol ratio—were less favourable in men with shorter legs, while showing reverse or no associations with trunk length. Fibrinogen levels were inversely associated with leg length and showed a weaker association with trunk length. Forced expiratory volume in one second was unrelated to leg length but strongly positively associated to trunk length. Other risk factors showed little association with components of stature. The risk of coronary heart disease was inversely related to leg length but showed little association with trunk length.
CONCLUSION—Leg length is the component of stature related to insulin resistance and coronary heart disease risk. As leg length is unrelated to lung function measures it is unlikely that these can explain the association in this cohort. Factors that influence leg length in adulthood—including nutrition...

Associations of height, leg length, and lung function with cardiovascular risk factors in the Midspan Family Study

Gunnell, D; Whitley, E; Upton, M; McConnachie, A; Davey, S; Watt, G
Fonte: BMJ Group Publicador: BMJ Group
Tipo: Artigo de Revista Científica
Publicado em /02/2003 EN
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Background: Taller people and those with better lung function are at reduced risk of coronary heart disease (CHD). Biological mechanisms for these associations are not well understood, but both measures may be markers for early life exposures. Some studies have shown that leg length, an indicator of pre-pubertal nutritional status, is the component of height most strongly associated with CHD risk. Other studies show that height-CHD associations are greatly attenuated when lung function is controlled for. This study examines (1) the association of height and the components of height (leg length and trunk length) with CHD risk factors and (2) the relative strength of the association of height and forced expiratory volume in one second (FEV1) with risk factors for CHD.

Childhood leg length and adult mortality: follow up of the Carnegie (Boyd Orr) Survey of Diet and Health in Pre-war Britain

Gunnell, D. J.; Davey, S; Frankel, S.; Nanchahal, K.; Braddon, F. E.; Pemberton, J.; Peters, T. J.
Fonte: BMJ Group Publicador: BMJ Group
Tipo: Artigo de Revista Científica
Publicado em /03/1998 EN
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OBJECTIVE: To investigate the relation between childhood height, its components--leg length and trunk length--and mortality in adulthood. DESIGN: Cohort study based on the Carnegie (Boyd Orr) Survey of diet and health in pre-war Britain, 1937-9. SETTING: The 14 centres in England and Scotland that participated in the Carnegie Survey and where children were examined. Scottish centres: Aberdeen, Dundee, West Wemyss, Coaltown of Wemyss, Hopeman, Methlick, Tarves, Barthol Chapel. English Centres: Liverpool, York-shire, Barrow in Furness, Wisbech, Fulham, and Bethnal Green. SUBJECTS: 2990 boys and girls aged between 2 years and 14 years 9 months when they were examined in 1937-9. These children were drawn from 1134 families who underwent a one week assessment of family diet and home circumstances. Of these, 2547 (85%) have been traced and flagged using the NHS Central Register. MAIN OUTCOME MEASURES: Age adjusted overall, coronary heart disease, and cancer mortality in men and women in relation to age and sex specific z scores for height, leg length, and trunk length. All analyses were adjusted for the possible confounding effects of childhood and adult socioeconomic circumstances and childhood diet. RESULTS: Leg length was the component of childhood height most strongly associated with socioeconomic and dietary exposures. There was no significant relation between childhood height and overall mortality. Height-mortality relations were observed in relation to both coronary heart disease (CHD) and cancer. Leg length was the component of height most strongly related to cause specific mortality. In men and women CHD mortality increased with decreasing childhood leg length. Men in the lowest leg length quintile had a relative risk (RR) of 2.5 (95% CI 1.0 to 6.2) compared to those with the longest legs (linear trend p = 0.14). Similarly...

Studies in Osteoarthritis of the Hip: Part II, * Osteoarthritis of the hip and leg-length disparity

Gofton, J. P.; Trueman, G. E.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em 08/05/1971 EN
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An x-ray method is described for the determination of leg-length inequality in the standing subject, Its precision is compared to that of other methods in current use. The geometrical considerations which are inherent in any radiographic method of leg-length determination are summarized. Sixty-seven patients with OA hip were studied; 62 were considered to be idiopathic and 36 of these idiopathic cases were superolateral in type. Measurements in these 36 patients showed significant leg-length disparity, most of the diseased hips being found on the side of the longer leg. If allowance is made for shortening due to disease, the frequency and bias of the disparity are highly significant. The strong association between OA hip of this type and a long leg suggests a causal relationship.

Leg Length Inequality

Sharpe, Colin R.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /02/1983 EN
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Leg length inequality, a common abnormality, can cause musculoskeletal pain, scoliosis, and osteoarthritis of the hip. Seven percent of the asymptomatic population has a leg length inequality greater than 12 mm; the incidence is considerably higher (13%-22%) in individuals complaining of low back pain. Correction can usually be accomplished by shoe modification, and can result in dramatic relief of pain. Leg length inequality of more than half an inch is considered clinically significant. Leg length measurement should be routine in all patients complaining of low back pain, hip pain, and atypical flank and lower quadrant pain. Correction might prove very cost-effective.

Complications of Ilizarov leg lengthening: a comparative study between patients with leg length discrepancy and short stature

Vargas Barreto, B.; Caton, J.; Merabet, Z.; Panisset, J. C.; Pracros, J. P.
Fonte: Springer-Verlag Publicador: Springer-Verlag
Tipo: Artigo de Revista Científica
EN
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The Ilizarov technique has been used to treat severe limb length discrepancy and short stature. However, complications of this treatment are frequent. Between 1984 and 2001, 57 patients (94 tibias) had an Ilizarov procedure for limb lengthening. Twenty patients had limb discrepancy and 37 had short stature. Their mean age was 20.2 years (range 15–34). The average limb lengthening was 8.37 cm (range 3.2–14.7), which was equivalent to 26% (range 9.2–60%) average tibial lengthening. A total of 90 complications were observed. Thirty-three unplanned procedures were required during the lengthening programme. Two patients stopped the lengthening programme. There was no difference in the complications in leg lengthening using Ilizarov technique between the group of patients with leg length discrepancy and the group with short stature. A good knowledge of the Ilizarov technique is necessary to perform a lengthening programme with a low rate of complications.

Leg Length, Body Proportion, and Health: A Review with a Note on Beauty

Bogin, Barry; Varela-Silva, Maria Inês
Fonte: Molecular Diversity Preservation International (MDPI) Publicador: Molecular Diversity Preservation International (MDPI)
Tipo: Artigo de Revista Científica
EN
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Decomposing stature into its major components is proving to be a useful strategy to assess the antecedents of disease, morbidity and death in adulthood. Human leg length (femur + tibia), sitting height (trunk length + head length) and their proportions, for example, (leg length/stature), or the sitting height ratio (sitting height/stature × 100), among others) are associated with epidemiological risk for overweight (fatness), coronary heart disease, diabetes, liver dysfunction and certain cancers. There is also wide support for the use of relative leg length as an indicator of the quality of the environment for growth during infancy, childhood and the juvenile years of development. Human beings follow a cephalo-caudal gradient of growth, the pattern of growth common to all mammals. A special feature of the human pattern is that between birth and puberty the legs grow relatively faster than other post-cranial body segments. For groups of children and youth, short stature due to relatively short legs (i.e., a high sitting height ratio) is generally a marker of an adverse environment. The development of human body proportions is the product of environmental x genomic interactions, although few if any specific genes are known. The HOXd and the short stature homeobox-containing gene (SHOX) are genomic regions that may be relevant to human body proportions. For example...

Leg length discrepancy in total hip arthroplasty: comparison of two methods of measurement

Sayed-Noor, Arkan S.; Hugo, Anders; Sjödén, Göran O.; Wretenberg, Per
Fonte: Springer-Verlag Publicador: Springer-Verlag
Tipo: Artigo de Revista Científica
EN
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Measurement of leg length discrepancy is an important part in planning a successful total hip arthroplasty (THA). Many clinical and radiological methods with variable degrees of accuracy have been advocated to carry out this measurement. We studied the accuracy of a commonly used clinical method by comparing it to a well-known and reliable radiological method. A total of 139 patients aged 44–89 (mean: 67.5 years) scheduled to undergo THA were examined for clinical and radiological leg length discrepancy measurements before and after the operation by the same observers. There was a poor correlation between the clinical and radiological methods preoperatively [r = 0.21, intra-class correlation coefficient (ICC) = 0.33]. The correlation was better postoperatively (r  = 0.45, ICC = 0.62). The clinical method used is not recommended for leg length discrepancy measurement preoperatively. Caution should even be taken when using this method postoperatively. The authors recommend using the radiological method when measuring leg length discrepancy as a part of planning for THA.

Does computer-assisted surgery benefit leg length restoration in total hip replacement? Navigation versus conventional freehand

Manzotti, Alfonso; Cerveri, Pietro; De Momi, Elena; Pullen, Chris; Confalonieri, Norberto
Fonte: Springer-Verlag Publicador: Springer-Verlag
Tipo: Artigo de Revista Científica
EN
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Leg length discrepancy following total hip replacement (THR) can contribute to poor hip function. Abnormal gait, pain, neurological disturbance and patient dissatisfaction have all been described as a result of leg length inequality after THR. The purpose of this study was to determine whether the use of computer navigation in THR can improve limb length restoration and early clinical outcomes. We performed a matched-pair study comparing 48 computer-assisted THR with 48 THRs performed using a traditional freehand alignment method. The same implant with a straight non-modular femoral stem was used in all cases. The navigation system used allowed the surgeon to monitor both acetabular cup placement and all the phases of femoral stem implantation including rasping. Patients were matched for age, sex, arthritis level, pre-operative diagnosis and pre-operative leg length discrepancy. At a minimum follow-up of six months, limb length discrepancy was measured using digital radiographs and a standardised protocol. The number of patients with a residual discrepancy of 10 mm or more and/or a post-operative over-lengthening were measured. The clinical outcome was evaluated using both the Harris Hip Score and the normalised Western Ontario and McMaster Universities (WOMAC) Arthritis Index. Restoration of limb length was significantly better in the computer-assisted THR group. The number of patients with a residual limb length discrepancy greater than 10 mm and/or a post-operative over-lengthening was significantly lower. No significant difference in the Harris Hip Score or normalised WOMAC Arthritis Index was seen between the two groups. The surgical time was significantly longer in the computer-assisted THR group. No post-operative dislocations were seen.

Leg length discrepancy after total hip arthroplasty: a review of literature

Desai, Aravind S.; Dramis, Asterios; Board, Tim N.
Fonte: Springer US Publicador: Springer US
Tipo: Artigo de Revista Científica
Publicado em 31/07/2013 EN
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Discrepancy of leg length is often considered to be a problem after total hip replacement and can adversely affect an otherwise excellent outcome. Furthermore, it has been associated with patient dissatisfaction and remains one of the most common reasons for litigation against the orthopedic community. As a consequence of the need to equalize leg length, several authors have sought to validate methods of minimizing limb length discrepancy based on preoperative planning with preoperative radiological templates or intraoperative methods of measurement. In this article, we present a review of the limb length discrepancy in total hip arthroplasty, its implications and several techniques to avoid it. We recommend that a combination of the above mentioned methods will give the best chance for the surgeon to minimise the risk of leg length discrepancy following total hip replacement.

The effect of simulating a leg-length discrepancy on pelvic position and spinal posture

Kwon, Yu-Jeong; Song, Minyoung; Baek, Il-Hun; Lee, Taesik
Fonte: The Society of Physical Therapy Science Publicador: The Society of Physical Therapy Science
Tipo: Artigo de Revista Científica
EN
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[Purpose] The purpose of this study was to examine how a leg-length discrepancy contributes to the pelvic position and spinal posture. [Subjects and Methods] A total of 20 subjects (10 males, 10 females) were examined during different artificially created leg-length inequalities (0–4 cm) using a platform. The pelvic tilt and torsion and the sagittal deviation of the spine were measured using the rasterstereographic device formetric 4D. [Results] Changes in platform height led to an increase in pelvic tilt and torsion, while no changes in the spinal posture were found with the different simulated leg-length inequalities. [Conclusion] Our study showed that a leg-length discrepancy may cause pelvic deviation and torsion, but may not lead to kyphosis and lordosis. Therefore, we consider that an artificially created leg-length discrepancy has a greater effect on pelvic position than spine position.

Changes in foot pressure elicited by 3D air balance exercise and pelvic stability exercise for functional leg-length discrepancy in adult women

Lee, Byung-Hoon; Kim, Jeong-Ja; Kim, Chan-Kyu
Fonte: The Society of Physical Therapy Science Publicador: The Society of Physical Therapy Science
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
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[Purpose] This study was conducted to examine the effect of pelvic stabilization exercise and 3D equipment exercise on adult women with Functional Leg-Length Discrepancy (FLLD). [Subjects and Methods] Twenty female students in their 20’s having FLLD without Structural Leg Length Discrepancy were selected. Exercise was performed for 50 min per session, three times a week, for six weeks. The Pelvic stabilization exercise (PSE) group performed pelvic stabilization exercises for 50 minutes, and the 3D exercise (3DE) group performed 3D Air Balance exercise for 10 minutes after performing the pelvic stabilization exercise program for 40 minutes. [Results] The PSE group showed statistically significant differences in tape measure method (TMM) and maximum pressure between pre-test and post-test, and 3DE showed statistically significant differences in TMM, the difference in maximum pressure, the difference in average pressure, and the difference in support area. At the end of the 6-week intervention, TMM, difference in maximum pressure, difference in average pressure, and difference in support area showed significantly greater reduction in the 3DE group. [Conclusion] The results show that 3D stabilization exercise was more effective at improving the stabilization of the deep muscles surrounding the pelvis and left-right muscular balance. We consider that 3D exercise should be included in exercise programs for improving pelvic cavity and spinal stability in the future.

Leg lengthening with a motorized nail in adolescents

Krieg, A.; Speth, B.; Foster, B.
Fonte: Lippincott Williams & Wilkins Publicador: Lippincott Williams & Wilkins
Tipo: Artigo de Revista Científica
Publicado em //2008 EN
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Leg lengthening by external fixation is associated with various difficulties. We evaluated eight adolescent patients who underwent leg lengthening with a motorized intramedullary lengthening device. We asked whether this method could reduce the time of hospitalization and rehabilitation and whether the incidence of complications commonly associated with external fixators could be reduced. We compared our preliminary results with those from other reports, with a focus on leg length achieved, time of rehabilitation, and rate of complications. The average leg-length discrepancy was 3.8 cm (range, 3–5 cm). The average lengthening distance was 3.8 cm (range, 2.9–4.7 cm). In six patients, leg lengthening was combined with successful correction of the mechanical axis alignment. The consolidation index averaged 26 days/cm (range, 19–41 days/cm). The average hospital stay was 9.6 days. No bone or soft tissue infections were observed. In comparison to other studies (1.0–2.8 complications/patient), our results suggest that the difficulties commonly associated with external fixators can be reduced with this method. It also allows good angular correction in patients with mechanical axis deviation. These features combined with a short time of hospitalization and rehabilitation make it a promising procedure for limb lengthening.; Andreas H. Krieg...

Desigualdade estrutural discreta de membros inferiores é suficiente para causar alteração cinética na marcha de corredores?; Is structural and mild leg length discrepancy enough to cause a kinetic change in runners' gait?

PEREIRA, Carla Sonsino; SACCO, Isabel de Camargo Neves
Fonte: Atha Comunicação & Editora Publicador: Atha Comunicação & Editora
Tipo: Artigo de Revista Científica
POR
Relevância na Pesquisa
67.469814%
Desigualdade de membros inferiores (DMI) está presente em cerca de 70% da população geral, podendo ser do tipo estrutural onde existe diferença no comprimento de estruturas ósseas, ou funcional, como resultado de alterações mecânicas dos membros inferiores. A desigualdade pode ainda ser classificada quanto a sua magnitude, sendo discreta, moderada, ou grave. As desigualdades discretas têm sido associadas especificamente à fratura por estresse, dor lombar e osteoartrite, e quando uma desigualdade está presente em indivíduos cuja sobrecarga mecânica é acentuada pela sua prática profissional, diária ou recreativa, estas alterações ortopédicas podem se manifestar precoce e gravemente. O objetivo deste estudo foi analisar e comparar a força reação do solo (FRS) durante a marcha de corredores com e sem DMI discreta. Os resultados mostraram que os sujeitos com desigualdades de 0,5 a 2,0 cm apresentaram no membro menor maiores valores da força vertical mínima (0,57 ± 0,07 PC) em relação ao membro maior (0,56 ± 0,08 PC). Logo, sujeitos com DMI discreta adotam mecanismos compensatórios capazes de gerar sobrecarga adicional ao sistema musculoesquelético para promover uma marcha simétrica como demonstrado pelos valores do Índice de Simetria Absoluto das variáveis da FRS vertical e horizontal.; Leg length discrepancy (LLD) affects about 70% of the general population...

Untreated asthma, final height and sitting height/leg length ratio in Chile

Bustos, Patricia; Smeeton, Nigel C.; Amigo Cartagena, Hugo Francisco; Vargas, Claudio; Rona, Roberto J.
Fonte: W B SAUNDERS CO LTD Publicador: W B SAUNDERS CO LTD
Tipo: Artículo de revista
EN
Relevância na Pesquisa
47.788496%
Objective: There is uncertainty as to whether asthma has an effect on final height. We investigated using subjective and objective assessments whether untreated asthma is associated with final height, leg length and sitting height to leg length ratio in an area of Chile in which almost no one received asthma treatment. Methods: We collected data on 1232 mates and females aged 22-28 years in a semi-rural area of Chile. Information on asthma was collected using the European Community Respiratory Health Survey (ECRHS) questionnaire. We assessed sensitisation to eight allergens and bronchial hyper-responsiveness (BHR) to methacholine as a dichotomous variable and as a log slope. Information on possible confounders in terms of smoking, birth weight, number of siblings and socio-economic factors such as household possessions, car ownership and education was available. Results: Regardless of the asthma assessment used, there was no association between asthma symptoms, diagnosis of asthma, atopy, BHR as log slope, binary or categorical and height, leg length or the ratio of sitting height to leg length. The tatter was used as a potentially more appropriate measure to assess a detriment of growth. Conclusion: Asthma as assessed in community studies is unrelated to final height or body proportions.