Página 1 dos resultados de 16 itens digitais encontrados em 0.012 segundos

Non-cardiogenic pulmonary oedema in the course of verapamil intoxication

Karti, S; Ulusoy, H; Yandi, M; Gunduz, A; Kosucu, M; Erol, K; Ratip, S
Fonte: BMJ Group Publicador: BMJ Group
Tipo: Artigo de Revista Científica
Publicado em /09/2002 EN
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Fermentative Utilization of Glycerol by Escherichia coli and Its Implications for the Production of Fuels and Chemicals▿

Murarka, Abhishek; Dharmadi, Yandi; Yazdani, Syed Shams; Gonzalez, Ramon
Fonte: American Society for Microbiology (ASM) Publicador: American Society for Microbiology (ASM)
Tipo: Artigo de Revista Científica
EN
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Availability, low prices, and a high degree of reduction make glycerol an ideal feedstock to produce reduced chemicals and fuels via anaerobic fermentation. Although glycerol metabolism in Escherichia coli had been thought to be restricted to respiratory conditions, we report here the utilization of this carbon source in the absence of electron acceptors. Cells grew fermentatively on glycerol and exhibited exponential growth at a maximum specific growth rate of 0.040 ± 0.003 h−1. The fermentative nature of glycerol metabolism was demonstrated through studies in which cell growth and glycerol utilization were observed despite blocking several respiratory processes. The incorporation of glycerol in cellular biomass was also investigated via nuclear magnetic resonance analysis of cultures in which either 50% U-13C-labeled or 100% unlabeled glycerol was used. These studies demonstrated that about 20% of the carbon incorporated into the protein fraction of biomass originated from glycerol. The use of U-13C-labeled glycerol also allowed the unambiguous identification of ethanol and succinic, acetic, and formic acids as the products of glycerol fermentation. The synthesis of ethanol was identified as a metabolic determinant of glycerol fermentation; this pathway fulfills energy requirements by generating...

Gluconacetobacter diazotrophicus Elicits a Sugarcane Defense Response Against a Pathogenic Bacteria Xanthomonas albilineans

Arencibia, Ariel D; Vinagre, Fabiano; Estevez, Yandi; Bernal, Aydiloide; Perez, Juana; Cavalcanti, Janaina; Santana, Ignacio; Hemerly, Adriana S
Fonte: Landes Bioscience Publicador: Landes Bioscience
Tipo: Artigo de Revista Científica
Publicado em //2006 EN
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A new role for the plant growth-promoting nitrogen-fixing endophytic bacteria Gluconacetobacter diazotrophicus has been identified and characterized while it is involved in the sugarcane-Xanthomonas albilineans pathogenic interactions. Living G.diazotrophicus possess and/or produce elicitor molecules which activate the sugarcane defense response resulting in the plant resistance to X. albilineans, in this particular case controlling the pathogen transmission to emerging agamic shoots. A total of 47 differentially expressed transcript derived fragments (TDFs) were identified by cDNA-AFLP. Transcripts showed significant homologies to genes of the ethylene signaling pathway (26%), proteins regulates by auxins (9%), β-1,3 Glucanase proteins (6%) and ubiquitin genes (4%), all major signaling mechanisms. Results point toward a form of induction of systemic resistance in sugarcane-G. diazotrophicus interactions which protect the plant against X. albilineans attack.

Etiology and Clinical Characteristics of Influenza-Like Illness (ILI) in Outpatients in Beijing, June 2010 to May 2011

Yang, XiaoHua; Yao, Yao; Chen, MeiFang; Yang, Xia; Xie, YanDi; Liu, YaFen; Zhao, XiuYing; Gao, Yan; Wei, Lai
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
Publicado em 04/01/2012 EN
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ADHESION TO SUBSTRATES INDUCES DENDRITIC CELL ENDOTHELIZATION AND DECREASES IMMUNOLOGICAL RESPONSE

Osterbur, Jacob; Sprague, Leslee; Muccioli, Maria; Pate, Michelle; Mansfield, Kristen; McGinty, John; Li, Yihan; Li, Yandi; Shirure, Venktesh; Courreges, Maria Cecilia; Benencia, Fabian
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
EN
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Dendritic cells (DCs) are antigen presenting cells capable of inducing specific immune responses against microbial infections, transplant antigens, or tumors. DCs have been shown to possess a high plasticity showing different phenotypes in response to their microenvironment. For example, tumor-associated DCs can acquire an angiogenic phenotype thus promoting tumor growth. Further, DCs cultured in vitro under different conditions are able to upregulate the expression of endothelial markers and to express angiogenic factors. Indeed, it has been shown that soluble factors such as VEGF of PGE-2, that are present in the microenvironment of several tumors, affect the biology of these cells. We hypothesize that in addition to soluble factors the adhesion to different substrates will also define the phenotype and function of DCs. Herewith we demonstrate that murine myeloid(m) DCs upregulate endothelial markers such as VE-Cadherin, and to a lesser extent TIE-2, and decrease their immune capabilities when cultured on solid surfaces as compared with the same cells cultured on ultra-low binding (ULB) surfaces. On the other hand, the expression of angiogenic molecules at the level of RNA was not different among these cultures. In order to further investigate this phenomenon we used the murine ID8 model of ovarian cancer which can generate solid tumors when cancer cells are injected subcutaneously or a malignant ascites when they are injected intraperitoneally. This model gave us the unique opportunity to investigate DCs in suspension or attached to solid surfaces under the influence of the same tumor cells. We were able to determine that DCs present in solid tumors showed higher levels of expression of endothelial markers and angiogenic molecules but were not able to respond to inflammatory stimuli at the same extent as DCs recovered from ascites. Moreover...

In vitro and in vivo evaluation of a sublingual fentanyl wafer formulation

Lim, Stephen CB; Paech, Michael J; Sunderland, Bruce; Liu, Yandi
Fonte: Dove Medical Press Publicador: Dove Medical Press
Tipo: Artigo de Revista Científica
Publicado em 12/04/2013 EN
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Efficacy of BET bromodomain inhibition in Kras-mutant non-small cell lung cancer

Shimamura, Takeshi; Chen, Zhao; Soucheray, Margaret; Carretero, Julian; Kikuchi, Eiki; Tchaicha, Jeremy H.; Gao, Yandi; Cheng, Katherine A.; Cohoon, Travis J.; Qi, Jun; Akbay, Esra; Kimmelman, Alec C.; Kung, Andrew L.; Bradner, James E.; Wong, Kwok-Kin
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
EN
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Chronic gastritis in China: a national multi-center survey

Du, Yiqi; Bai, Yu; Xie, Pei; Fang, Jingyuan; Wang, Xiaozhong; Hou, Xiaohua; Tian, Dean; Wang, Chengdang; Liu, Yandi; Sha, Weihong; Wang, Bangmao; Li, Yanqing; Zhang, Guoliang; Li, Yan; Shi, Ruihua; Xu, Jianming; Li, Youming; Huang, Minghe; Han, Shengxi; L
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Artigo de Revista Científica
Publicado em 07/02/2014 EN
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High-throughput, cost-effective verification of structural DNA assembly

Dharmadi, Yandi; Patel, Kedar; Shapland, Elaine; Hollis, Daniel; Slaby, Todd; Klinkner, Nicole; Dean, Jed; Chandran, Sunil S.
Fonte: Oxford University Press Publicador: Oxford University Press
Tipo: Artigo de Revista Científica
EN
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DNA ‘assembly’ from ‘building blocks’ remains a cornerstone in synthetic biology, whether it be for gene synthesis (∼1 kb), pathway engineering (∼10 kb) or synthetic genomes (>100 kb). Despite numerous advances in the techniques used for DNA assembly, verification of the assembly is still a necessity, which becomes cost-prohibitive and a logistical challenge with increasing scale. Here we describe for the first time a comprehensive, high-throughput solution for structural DNA assembly verification by restriction digest using exhaustive in silico enzyme screening, rolling circle amplification of plasmid DNA, capillary electrophoresis and automated digest pattern recognition. This low-cost and robust methodology has been successfully used to screen over 31 000 clones of DNA constructs at <$1 per sample.

The absolute bioavailability of racemic ketamine from a novel sublingual formulation

Rolan, Paul; Lim, Stephen; Sunderland, Vivian; Liu, Yandi; Molnar, Valeria
Fonte: Blackwell Science Inc Publicador: Blackwell Science Inc
Tipo: Artigo de Revista Científica
EN
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Simulation of correlated variables: a comparison of approaches with a case study from the Yandi Channel iron deposit.

De-Vitry, Chris
Fonte: Universidade de Adelaide Publicador: Universidade de Adelaide
Tipo: Tese de Doutorado
Publicado em //2010
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Conditional Simulation of correlated assay variables is a subject of significant recent and current development. The objective of this thesis is to evaluate the available approaches in this area for mining applications. BHP Billiton’s (BHPB) Yandi Channel Iron Deposit (Yandi CID) in Western Australia was selected for these tests. The Yandi CID is 150 km by road North of the town of Newman in the Pilbara region. This channel iron deposit (CID) infills the meandering tertiary palaeochannels of Marillana Creek, which are 450m - 750m wide and approximately 100m deep in the centre. The deposits outcrop as a series of low mesas beside the present day creeks and were divided into three areas (Western, Central and Eastern) within which individual mesas are numbered. A North-South trending part of the channel (mesas C4, and part of C5) is the focus of this study. Drilling of the C4 and C5 mesas is on grids varying from 25m x 50m to 100m x 100m. Although the Yandi CID is mined for iron ore, the concentrations of the contaminants Al₂O₃, SiO₂ and P₂O₅ are economically critical. The loss on ignition (LOI), while not strictly speaking a contaminant, is also an important product characteristic for iron ore customers. The correlations between the assay variables and their relative abundances vary from sample to sample. For resource modelling...

Training in Medical Semiotics: A Characterization Based on Practice; Formación en semiología médica: una caracterización desde la práctica; Formação em semiologia médica: uma caracterização a partir da prática

Pineda, Carlos Andres; Universidad del Valle; Garcia-Perdomo, Herney Andrés; Universidad del Valle; Tehelen, Juan Pablo; Universidad del Calle; Ruiz, Omar; Universidad del Valle, Colombia; Yandi, Jhon Alexander; Universidad del Valle, Colombia
Fonte: Universidad de la Sabana Publicador: Universidad de la Sabana
Tipo: Artigo de Revista Científica
SPA
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The article characterizes the semiotic training provided to medical students at universities in the city of Cali, Colombia.  A descriptive study was done to review information on the semiotics curriculum in medical studies at five institutions of higher education in Cali, using a hermeneutical approach.  Objectives or skills, teaching strategies, didactic resources and forms of assessment were found to be homogeneous, as were credits, time intensity, curriculum content and sequencing.; El artículo caracteriza la formación semiológica de los estudiantes de medicina en universidades de la ciudad de Cali, Colombia. Se realizó un estudio descriptivo en el que se revisó la información concerniente al currículo de semiología de los programas de medicina de cinco universidades de la ciudad, bajo una metodología hermenéutica. Se encontró homogeneidad en lo relacionado con objetivos o competencias, estrategias pedagógicas, recursos didácticos y formas de evaluación. Del mismo modo, en los créditos, las intensidades horarias, la secuenciación curricular y en los contenidos.; Este artigo caracteriza a formação semiológica dos estudantes de Medicina em universidades da cidade de Cali (Colômbia). Realizou-se um estudo descritivo no qual se revisou a informação concernente ao currículo de semiologia dos programas de Medicina de cinco universidades da cidade de Cali...

Training in Medical Semiotics: A Characterization Based on Practice; Formación en semiología médica: una caracterización desde la práctica; Formação em semiologia médica: uma caracterização a partir da prática

Pineda, Carlos Andres; Universidad del Valle; Garcia-Perdomo, Herney Andrés; Universidad del Valle; Tehelen, Juan Pablo; Universidad del Calle; Ruiz, Omar; Universidad del Valle, Colombia; Yandi, Jhon Alexander; Universidad del Valle, Colombia
Fonte: Universidad de la Sabana Publicador: Universidad de la Sabana
Tipo: Artigo de Revista Científica
SPA
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16.876787%
The article characterizes the semiotic training provided to medical students at universities in the city of Cali, Colombia.  A descriptive study was done to review information on the semiotics curriculum in medical studies at five institutions of higher education in Cali, using a hermeneutical approach.  Objectives or skills, teaching strategies, didactic resources and forms of assessment were found to be homogeneous, as were credits, time intensity, curriculum content and sequencing.; El artículo caracteriza la formación semiológica de los estudiantes de medicina en universidades de la ciudad de Cali, Colombia. Se realizó un estudio descriptivo en el que se revisó la información concerniente al currículo de semiología de los programas de medicina de cinco universidades de la ciudad, bajo una metodología hermenéutica. Se encontró homogeneidad en lo relacionado con objetivos o competencias, estrategias pedagógicas, recursos didácticos y formas de evaluación. Del mismo modo, en los créditos, las intensidades horarias, la secuenciación curricular y en los contenidos.; Este artigo caracteriza a formação semiológica dos estudantes de Medicina em universidades da cidade de Cali (Colômbia). Realizou-se um estudo descritivo no qual se revisou a informação concernente ao currículo de semiologia dos programas de Medicina de cinco universidades da cidade de Cali...

Alineamiento múltiple de secuencias con T-Coffee : una aproximación paralela

Naranjo Basalo, Yandi; Hernández Budé, Porfidio
Fonte: Universidade Autônoma de Barcelona Publicador: Universidade Autônoma de Barcelona
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em //2009 SPA
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Las aplicaciones de alineamiento múltiple de secuencias son prototipos de aplicaciones que requieren elevada potencia de cómputo y memoria. Se destacan por la relevancia científica que tienen los resultados que brindan a investigaciones científicas en el campo de la biomedicina, genética y farmacología. Las aplicaciones de alineamiento múltiple tienen la limitante de que no son capaces de procesar miles de secuencias, por lo que se hace necesario crear un modelo para resolver la problemática. Analizando el volumen de datos que se manipulan en el área de las ciencias biológica y la complejidad de los algoritmos de alineamiento de secuencias, la única vía de solución del problema es a través de la utilización de entornos de cómputo paralelos y la computación de altas prestaciones. La investigación realizada por nosotros tiene como objetivo la creación de un modelo paralelo que le permita a los algoritmos de alineamiento múltiple aumentar el número de secuencias a procesar, tratando de mantener la calidad en los resultados para garantizar la precisión científica. El modelo que proponemos emplea como base la clusterización de las secuencias de entrada utilizando criterios biológicos que permiten mantener la calidad de los resultados. Además...

Age and palaeoenvironmental constraints on the genesis of the Yandi channel iron deposits, Marillana Formation, Pilbara, northwestern Australia

Macphail, Michael; Stone, M S
Fonte: Blackwell Publishing Ltd Publicador: Blackwell Publishing Ltd
Tipo: Artigo de Revista Científica
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Fossil pollen and spores preserved in organic-rich claystones near the base of the palaeochannel hosting the Tertiary Yandi channel iron deposits (CID) provide an in situ constraint on the age of this world-class orebody. This assemblage also aids understanding of the palaeoenvironment leading to the deposition and preservation of the host Marillana Formation. The provisional Early Oligocene age of claystones links the genesis of the Yandi CID to the profound disruption of global climates and oceanography at the Eocene-Oligocene transition (Terminal Eocene Event) and provides circumstantial evidence that ore formation was linked to the development of a warm south-flowing proto-Leeuwin Current along the Pilbara coast. It is likely that rainfall increased but remained strongly seasonal (monsoonal?) as global climates wormed during the Late Oligocene - Early Miocene. The same fossil evidence indicates that wood fragments, the iron-oxide-replaced remains of which are a significant component of cemented goethitic gravel making up CID, came from Casuarinaceae- and Myrtaceae-dominated sclerophyll communities lining the channel banks. Increasingly dry conditions since the late Early Miocene Climatic Optimum are likely to have contributed to the preservation of CID at Yandi.

Genetic disruption of Ano5 in mice does not recapitulate human ANO5-deficient muscular dystrophy

Xu, Jing; El Refaey, Mona; Xu, Li; Zhao, Lixia; Gao, Yandi; Floyd, Kyle; Karaze, Tallib; Janssen, Paul M. L.; Han, Renzhi
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Text
Publicado em 21/12/2015 EN
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