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Production of chitosan based films enriched with essential oils for biomedical applications

Vilas-Boas, D.; Leite, E.; Fernandes, I.P.; Amaral, J.S.; Barreiro, M.F.
Fonte: Instituto Politécnico de Bragança Publicador: Instituto Politécnico de Bragança
Tipo: Conferência ou Objeto de Conferência
ENG
Relevância na Pesquisa
66.14%
Chitosan is a natural polysaccharide composed of β-(1-4) glucosamine and N-acetylglucosamine residues. Due to its safety and non-toxicity, biocompatibility, biodegradability and antimicrobial properties, its use in biomedical applications has been suggested in several studies. The objective of this work was the production of chitosan based films enriched with essential oils, to further improve the natural antimicrobial properties of chitosan. The films were produced at room temperature by evaporation. Different parameters were tested, namely the solution volume needed to prepare the films, the type of acid used to solubilize chitosan, the concentration of essential oil and the emulsifier type and concentration.

Nanoencapsulation II. Biomedical applications and current status of peptide and protein nanoparticulate delivery systems

Reis, Catarina Pinto; Neufeld, Ronald J.; Ribeiro, António J.; Veiga, Francisco
Fonte: Universidade de Coimbra Publicador: Universidade de Coimbra
Tipo: Artigo de Revista Científica Formato: aplication/PDF
ENG
Relevância na Pesquisa
66.14%
The concept of polymeric nanoparticles for the design of new drug delivery systems emerged a few years ago, and recent rapid advances in nanotechnology have offered a wealth of new opportunities for diagnosis and therapy of various diseases. Recent progress has made possible the engineering of nanoparticles to allow the site-specific delivery of drugs and to improve the pharmacokinetic profile of numerous compounds with biomedical applications such as peptide and protein drugs. Biologically active peptides and their analogues are becoming an increasingly important class of drugs. Their use for human and animal treatment is problematic, however, because some of these drugs are generally ineffective when taken orally and thus have been administered chiefly by the parenteral route. This review covers some of the historical and recent advances of nanotechnology and concludes that polymeric nanoparticles show great promise as a tool for the development of peptide drug delivery systems.; http://www.sciencedirect.com/science/article/B7MDB-4K674VB-2/1/583cefa271f0f3f125e0741c240b8a9e

Stimuli-responsive magnetic particles for biomedical applications

MEDEIROS, S. F.; SANTOS, A. M.; FESSI, H.; ELAISSARI, A.
Fonte: ELSEVIER SCIENCE BV Publicador: ELSEVIER SCIENCE BV
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
66.33%
In recent years, magnetic nanoparticles have been studied due to their potential applications as magnetic carriers in biomedical area. These materials have been increasingly exploited as efficient delivery vectors, leading to opportunities of use as magnetic resonance imaging (MRI) agents, mediators of hyperthermia cancer treatment and in targeted therapies. Much attention has been also focused on ""smart"" polymers, which are able to respond to environmental changes, such as changes in the temperature and pH. In this context, this article reviews the state-of-the art in stimuli-responsive magnetic systems for biomedical applications. The paper describes different types of stimuli-sensitive systems, mainly temperature- and pH sensitive polymers, the combination of this characteristic with magnetic properties and, finally, it gives an account of their preparation methods. The article also discusses the main in vivo biomedical applications of such materials. A survey of the recent literature on various stimuli-responsive magnetic gels in biomedical applications is also included. (C) 2010 Elsevier B.V. All rights reserved.; Capes; CNPq

Biological monitoring of a promissory xenogenic pin for biomedical applications: a preliminary intraosseous study in rats

Zambuzzi, Willian Fernando; Oliveira, Rodrigo Cardoso; Subitoni, Bruno Leite; Menezes, Renato; Taga, Rumio; Granjeiro, Jose Mauro
Fonte: WILEY-BLACKWELL; MALDEN Publicador: WILEY-BLACKWELL; MALDEN
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
56.19%
Objectives: Over the last years, it is known that in some cases metal devices for biomedical applications present some disadvantages suggesting absorbable materials (natural or synthetic) as an alternative of choice. Here, our goal was to evaluate the biological response of a xenogenic pin, derived from bovine cortical bone, intraosseously implanted in the femur of rats. Material and methods: After 10, 14, 30 and 60 days from implantation, the animals (n = 5/period) were killed and the femurs carefully collected and dissected out under histological demands. For identifying the osteoclastogenesis level at 60 days, we performed the immunohistochemisty approach using antibody against RANKL. Results: Interestingly, our results showed that the incidence of neutrophils and leukocytes was observed only at the beginning (10 days). Clear evidences of pin degradation by host cells started at 14 days and it was more intensive at 60 days, when we detected the majority of the presence of giant multinucleated cells, which were very similar to osteoclast cells contacting the implanted pin. To check osteoclastogenesis at 60 days, we evaluated RANKL expression and it was positive for those resident multinucleated cells while a new bone deposition was verified surrounding the pins in all evaluated periods. Conclusions: Altogether...

Nanopartículas magnéticas de cobalto metálico e ferrita de cobalto recobertas com ouro como materiais biocompatíveis visando aplicações em biomedicina; Magnetic nanoparticles of gold-coated cobalt and cobalt ferrite as biocompatible materials for biomedical applications

Souza Junior, João Batista
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 24/05/2012 PT
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66.23%
Atualmente, as nanopartículas superparamagnéticas despertam enorme interesse científico devido sua grande variedade de aplicações em biomedicina, tanto na área de diagnóstico quanto no tratamento de enfermidades. Embora muitos materiais vem sendo estudados, os óxidos de ferro (magnetita e maghemita) apresentam maiores avanços nos estudos para aplicações em medicina. A preferência por óxidos de ferro se deve a baixa toxicidade destas partículas quando comparado as nanopartículas metálicas ou ligas. Entretanto, as nanopartículas destes óxidos possuem baixas magnetizações de saturação que diminuem ainda mais com as sucessivas etapas de recobrimento necessárias para conferir funcionalidade a estas partículas. Desse modo, há uma necessidade atual para o desenvolvimento de nanopartículas superparamagnéticas com elevada magnetização, baixa toxicidade e maior facilidade de funcionalização da sua superfície com biopolímeros e agentes funcionalizantes. Neste trabalho, nanopartículas superparamagnéticas de cobalto metálico e ferrita de cobalto foram sintetizadas e suas propriedades magnéticas foram comparadas com a magnetita. Nanopartículas de cobalto foram escolhidas, pois seu elevado comportamento ferromagnético é menor apenas que o ferro metálico...

Iron Oxide Versus Fe55Pt45/Fe3O4: Improved Magnetic Properties of Core/Shell Nanoparticles for Biomedical Applications

Varanda, L. C.; Imaizumi, M.; Santos, F. J.; Jafelicci, M.
Fonte: Institute of Electrical and Electronics Engineers (IEEE) Publicador: Institute of Electrical and Electronics Engineers (IEEE)
Tipo: Artigo de Revista Científica Formato: 4448-4451
ENG
Relevância na Pesquisa
66.14%
In this paper, synthesis of the Fe55Pt45/Fe3O4 core/shell structured nanoparticles using the modified polyol process combined with the seed-mediated growth method is reported. Iron oxide shell thickness was tuned controlling the Fe(acac)(3)/FePt seeds in the reaction medium. Annealing of the core/shell structure leads to iron-rich layer formation around the hard FePt phase in the nanoparticle core. However, the 2 nm Fe3O4 shell thickness seems to be the limit to obtain the enhanced magnetization close to the alpha-Fe and preserving an iron oxide shell after annealing at 500 degrees C for 30 min in a reducing atmosphere. The presence of both the oxide layer on nanoparticle surface and an intermediate iron-rich FePt layer after annealing promote strong decreases in the coercive field of the 2-nm-oxide shell thickness. These annealed nanoparticles were functionalized with dextran, presenting the enhanced characteristics for biomedical applications such as higher magnetization, very low coercivity, and a slightly iron oxide passivated layer, which leads an easy functionalization and decreases the nanoparticle toxicity.

Porous titanium scaffolds produced by powder metallurgy for biomedical applications

Vasconcellos, Luana Marotta Reis de; Oliveira, Marize Varella de; Alencastro Graça, Mário Lima de; Vasconcellos, Luis Gustavo Oliveira de; Carvalho, Yasmin Rodarte; Cairo, Carlos Alberto Alves
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Artigo de Revista Científica Formato: 275-280
ENG
Relevância na Pesquisa
66.29%
Porous titanium scaffolds are promising materials for biomedical applications such as prosthetic anchors, fillers and bone reconstruction. This study evaluated the bone/titanium interface of scaffolds with interconnected pores prepared by powder metallurgy, using scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). Porous scaffolds and dense samples were implanted in the tibia of rabbits, which were subsequently killed 1, 4, and 8 weeks after surgery. Initial bone neoformation was observed one week after implantation. Bone ingrowth in pores and the Ca/P ratio at the interface were remarkably enhanced at 4 and 8 weeks. The results showed that the interconnected pores of the titanium scaffolds promoted bone ingrowth, which increased over time. The powder metallurgy technique thus proved effective in producing porous scaffolds and dense titanium for biomedical applications, allowing for adequate control of pore size and porosity and promoting bone ingrowth.

Green processing of porous chitin structures for biomedical applications combining ionic liquids and supercritical fluid technology

Silva, S. S.; Mano, J. F.; Reis, R. L.; Carvalho, Ana Paula; Duarte, Ana Rita C.
Fonte: Elsevier Publicador: Elsevier
Tipo: Artigo de Revista Científica
Publicado em /03/2011 ENG
Relevância na Pesquisa
66.14%
The application of green chemistry principles in the processing of materials for advanced technologies is a steadily increasing field of research. In this work porous chitin-based materials were developed by combining the processing of chitin using ionic liquids (ILs)as a green solvent together with the use of super- critical fluid technology(SCF) as clean technology.Chitin was dissolved in 1-butyl-3-imidazolium acetate,followed by regeneration of the polymer in ethanol in specific moulds.The IL was removed using Soxhlet extraction and successive steps of extraction with SCF using carbon dioxide/ethanol ratios of 50/ 50 and70/30.The developed porous chitin-based structures (ChIL)can be classified as mesoporous materials,with very low density and high porosity.The cytotoxicity of ChIL extracts was investigated using L929 fibroblast like cells,and the results demonstrated that the produced materials have extremely lowcytotoxicityl evels.Therefore,the findings suggest that the porous chitin structures may be potential candidates for a number of biomedical applications,including tissue engineering.; Fundação para a Ciência e Tecnologia (FCT); European NoE EXPERTISSUES(NMP3-CT-2004-500283)

Materials of marine origin : a review on polymers and ceramics of biomedical interest

Silva, Tiago H.; Alves, A.; Ferreira, B. M.; Oliveira, Joaquim M.; Reys, L. L.; Ferreira, R. J. F.; Sousa, R. A.; Silva, S. S.; Mano, J. F.; Reis, R. L.
Fonte: Maney Publishing Publicador: Maney Publishing
Tipo: Artigo de Revista Científica
Publicado em //2012 ENG
Relevância na Pesquisa
56.19%
Marine organisms are constituted by materials with a vast range of properties and characteristics that may justify their potential application within the biomedical field. Moreover, assuring the sustainable exploitation of natural marine resources, the valorisation of residues from marine origin, like those obtained from food processing, constitutes a highly interesting platform for development of novel biomaterials, with both economic and environmental benefits. In this perspective, an increasing number of different types of compounds are being isolated from aquatic organisms and transformed into profitable products for health applications, including controlled drug delivery and tissue engineering devices. This report reviews the work that is being developed on the isolation and characterisation of some polysaccharides, proteins, glycosaminoglycans and ceramics from marine raw materials. Emphasis is given to agar, alginates, carrageenans, chitin and chitosan, among other polysaccharides, collagen, glycosaminoglycans such as chondroitin sulphate, heparin and hyaluronic acid, calcium phosphorous compounds and biosilica. Finally, this report ends by reviewing the application of the previously mentioned materials on specific biomedical applications...

Photonic sensors based on flexible materials with FBGs for use on biomedical applications

Silva, A. F.; Rocha, R. P.; Carmo, J. P.; Correia, J. H.
Fonte: InTech Publicador: InTech
Tipo: Parte de Livro
Publicado em 15/05/2013 ENG
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66.14%
This chapter is intended for presenting biomedical applications of FBGs embedded into flexible carriers for enhancing the sensitivity and to provide interference-free instrumentation.; This work was fully supported by the Algoritmi’s Strategic Project UI 319-2011-2012, under the Portuguese Foundation for Science and Technology grant Pest C/EEI/UI0319/2011.

Porous titanium scaffolds produced by powder metallurgy for biomedical applications

Vasconcellos,Luana Marotta Reis de; Oliveira,Marize Varella de; Graça,Mário Lima de Alencastro; Vasconcellos,Luis Gustavo Oliveira de; Carvalho,Yasmin Rodarte; Cairo,Carlos Alberto Alves
Fonte: ABM, ABC, ABPol Publicador: ABM, ABC, ABPol
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/09/2008 EN
Relevância na Pesquisa
56.19%
Porous titanium scaffolds are promising materials for biomedical applications such as prosthetic anchors, fillers and bone reconstruction. This study evaluated the bone/titanium interface of scaffolds with interconnected pores prepared by powder metallurgy, using scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). Porous scaffolds and dense samples were implanted in the tibia of rabbits, which were subsequently killed 1, 4, and 8 weeks after surgery. Initial bone neoformation was observed one week after implantation. Bone ingrowth in pores and the Ca/P ratio at the interface were remarkably enhanced at 4 and 8 weeks. The results showed that the interconnected pores of the titanium scaffolds promoted bone ingrowth, which increased over time. The powder metallurgy technique thus proved effective in producing porous scaffolds and dense titanium for biomedical applications, allowing for adequate control of pore size and porosity and promoting bone ingrowth.

Wireless microsystems for biomedical applications

Carmo,João Paulo; Correia,José Higino
Fonte: Sociedade Brasileira de Microondas e Optoeletrônica e Sociedade Brasileira de Eletromagnetismo Publicador: Sociedade Brasileira de Microondas e Optoeletrônica e Sociedade Brasileira de Eletromagnetismo
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2013 EN
Relevância na Pesquisa
66.14%
This paper presents a review with the state-of-the-art of wireless microsystems for biomedical applications. Aspects including the radio-frequency systems, data acquisition, application specificities (especially those in the context of implantable devices), power consumption and issues associated to their integration are presented. A review of COTS (Commercial Off-The-Shelf) systems and new concepts and technologies are also presented.

New optoacoustic spectroscopy system to quality and characterize absorbers in turbid media: experimental mesaurements and analysis of gold nanoparticles for biomedical applications

Cunningham, Vincent Brian
Fonte: Universidade Carlos III de Madrid Publicador: Universidade Carlos III de Madrid
Tipo: Tese de Doutorado Formato: application/octet-stream; application/octet-stream; application/pdf; application/pdf
ENG
Relevância na Pesquisa
66.25%
The limited penetration depth of optical energy in biological media is primarily due to the high level of optical scattering. This optical attenuation places an upper limit on optical, diagnostic, and therapeutic techniques for in in-vivo applications. The optoacoustic technique combines the unique advantages of light and sound, providing high levels of contrast, while maintaining the spatial resolution of acoustic techniques. The importance of colloidal gold solutions, as optical contrast agents in optoacoustic biomedical applications, is to increase the absorption of optical energy in areas where scattering is dominant and has prompted the study presented in this thesis on their characterization and quantification. It has been demonstrated that the acoustic transients generated from the optical irradiation are directly proportional to the wavelength dependent absorbed optical energy. Advantage has been taken of this fact to design two separate optoacoustic schemes. The first has been implemented to quantify the optical absorption, at a single laser wavelength, of spherical gold nanoparticles embedded within a medium that simulates the high scattering nature of soft tissue. The second has been designed to obtain the spectroscopic profile of such gold nanostructures. The results obtained from the optoacoustic analysis are compared to those from a reference measurement scheme...

A Self-Referenced Optical Intensity Sensor Network Using POFBGs for Biomedical Applications

Tapetado Moraleda, Alberto; Sánchez Montero, David; Webb, David J.; Vázquez, Carmen
Fonte: Universidade Carlos III de Madrid Publicador: Universidade Carlos III de Madrid
Tipo: info:eu-repo/semantics/publishedVersion; info:eu-repo/semantics/article
Publicado em 12/12/2014 ENG
Relevância na Pesquisa
66.14%
This work bridges the gap between the remote interrogation of multiple optical sensors and the advantages of using inherently biocompatible low-cost polymer optical fiber (POF)-based photonic sensing. A novel hybrid sensor network combining both silica fiber Bragg gratings (FBG) and polymer FBGs (POFBG) is analyzed. The topology is compatible with WDM networks so multiple remote sensors can be addressed providing high scalability. A central monitoring unit with virtual data processing is implemented, which could be remotely located up to units of km away. The feasibility of the proposed solution for potential medical environments and biomedical applications is shown.; This work was supported by the Spanish Ministry of Economía y Competitividad under grant TEC2012-37983-C03-02, Comunidad de Madrid under grant S2013/MIT-2790, and by ICT COST action TD1001. The authors wish to thanks Lutful Khan and Ada Abang for the help given to fabricate the mPOF Bragg gratings.

Properties and Performance of Ultrafine Grained Titanium for Biomedical Applications

Fernandes,Daniel Jogaib; Elias,Carlos Nelson; Valiev,Ruslan Zufarovich
Fonte: ABM, ABC, ABPol Publicador: ABM, ABC, ABPol
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2015 EN
Relevância na Pesquisa
56.33%
The use of materials for biomedical applications has become vital to enhance the quality of life and longevity of human beings. Commercially pure titanium (cpTi) and titanium alloys are the most adequate materials for some biomedical applications, but cpTi and the Ti-6Al-4V alloy (Ti G5) have limitations for biomedical application due to low mechanical strength and the possibility of ion release, respectively. In order to address this problem, commercially pure ultrafine grained titanium (UFG Ti) obtained by severe plastic deformation (SPD) has been suggested as a promising alternative for biomedical applications. This thermomechanical process is able to improve the strength of cpTi and titanium alloys while keeping their excellent biocompatibility. The purpose of this review was to compare the mechanical strength of UFG Ti, cpTi and a Ti G5 alloy. In addition, the biological performance of UFG Ti was also evaluated by in vivo testing. Prodigious improvements were seen in surface topography, wettability and in homogeneity of oxide layer. The overall improvements in microstructure provided by ECAP technique coupled with surface etching resulted in a remarkable performance of cpTi alloy for biomedical applications.

Characterization of a new beta titanium alloy, Ti-12Mo-3Nb, for biomedical applications

Gabriel, S. B.; Panaino, J. V. P.; Santos, I. D.; Araujo, L. S.; Mei, P. R.; Almeida, L. H. de; Nunes, C. A.
Fonte: ELSEVIER SCIENCE SA; LAUSANNE Publicador: ELSEVIER SCIENCE SA; LAUSANNE
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
66.19%
In recent years, different beta titanium alloys have been developed for biomedical applications with a combination of mechanical properties including a low Young's modulus, high strength, fatigue resistance and good ductility with excellent corrosion resistance. From this perspective, a new metastable beta titanium Ti-12Mo-3Nb alloy was developed with the replacement of both vanadium and aluminum from the traditional Ti-6Al-4V alloy. This paper presents the microstructure, mechanical properties and corrosion resistance of the Ti-12Mo-3Nb alloy heat-treated at 950 degrees C for 1 h. The material was characterized by X-ray diffraction and by scanning electron microscopy. Tensile tests were carried out at room temperature. Corrosion tests were performed using Ringer's solution at 25 degrees C. The results showed that this alloy could potentially be used for biomedical purposes due to its good mechanical properties and spontaneous passivation. (c) 2011 Elsevier B.V. All rights reserved.; CNPq; CNPq; FAPERJ; FAPERJ; CAPES; CAPES

Characterization of a new beta titanium alloy, Ti-12Mo-3Nb, for biomedical applications

Gabriel, S. B.; Panaino, J. V. P.; Santos, I. D.; Araujo, L. S.; Mei, P. R.; de Almeida, L. H.; Nunes, A.
Fonte: Elsevier; Lausanne Publicador: Elsevier; Lausanne
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
66.19%
In recent years, different beta titanium alloys have been developed for biomedical applications with a combination of mechanical properties including a low Young's modulus, high strength, fatigue resistance and good ductility with excellent corrosion resistance. From this perspective, a new metastable beta titanium Ti-12Mo-3Nb alloy was developed with the replacement of both vanadium and aluminum from the traditional Ti-6Al-4V alloy. This paper presents the microstructure, mechanical properties and corrosion resistance of the Ti-12Mo-3Nb alloy heat-treated at 950 degrees C for 1 h. The material was characterized by X-ray diffraction and by scanning electron microscopy. Tensile tests were carried out at room temperature. Corrosion tests were performed using Ringer's solution at 25 degrees C. The results showed that this alloy could potentially be used for biomedical purposes due to its good mechanical properties and spontaneous passivation. (c) 2011 Elsevier B.V. All rights reserved.; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Biodegradable polymers and composites in biomedical applications : from catgut to tissue engineering - Part 1 - Available systems and their properties

Gomes, Manuela E.; Reis, R. L.
Fonte: Maney Pub. Publicador: Maney Pub.
Tipo: Artigo de Revista Científica
Publicado em //2004 ENG
Relevância na Pesquisa
66.25%
Biodegradable polymers form a unique class of materials that created an entirely new concept when originally proposed as biomaterials. That is, for the first time, a material performing a structural application was designed to be completely resorbed and to become weaker over time. This concept was first applied successfully with catgut sutures and later, with more arguable results, on bone fixation plates and pins. Current research on new and improved biodegradable polymers is focused on more sophisticated biomedical applications to solve patients' problems with higher efficacy and the least possible pain. One example is tissue engineering, in which a biodegradable scaffold seeded with an appropriate cell type provides a substitute for damaged human tissue while the natural process of regeneration is completed. An overview is given of the degradation properties and mechanisms of biodegradable polymers, their processability and biocompatibility, focusing on the aspects most relevant to biomedical applications. The main families of biodegradable polymeric systems are described and the systems that are commercially available or that are currently being studied and proposed for specific medical applications are reviewed.

Quinoxaline, its derivatives and applications: A state of the art review.

Pereira, Joana; Pessoa, Ana M.; Cordeiro, M. Natália S.; Fernandes, Rúben; Prudêncio, Cristina; Noronha, João Paulo; Vieira, Mónica
Fonte: European Journal of Medicinal Chemistry Publicador: European Journal of Medicinal Chemistry
Tipo: Artigo de Revista Científica
Publicado em 01/07/2014 ENG
Relevância na Pesquisa
56.14%
Quinoxaline derivatives are an important class of heterocycle compounds, where N replaces some carbon atoms in the ring of naphthalene. Its molecular formula is C8H6N2, formed by the fusion of two aromatic rings, benzene and pyrazine. It is rare in natural state, but their synthesis is easy to perform. In this review the State of the Art will be presented, which includes a summary of the progress made over the past years in the knowledge of the structure and mechanism of the quinoxaline and quinoxaline derivatives, associated medical and biomedical value as well as industrial value. Modifying quinoxaline structure it is possible to obtain a wide variety of biomedical applications, namely antimicrobial activities and chronic and metabolic diseases treatment.

Development of electrospun nanofibers for biomedical applications: state of the art in Latin America

Caracciolo, Pablo Christian; Cortez Tornello, Pablo Roberto; Montini Ballarin, Florencia; Abraham, Gustavo Abel
Fonte: American Scientific Publishers Publicador: American Scientific Publishers
Tipo: info:eu-repo/semantics/article; info:ar-repo/semantics/artículo; info:eu-repo/semantics/publishedVersion Formato: application/pdf
ENG
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66.29%
Electrospinning is a powerful processing technique with huge potential in many attractive and cutting-edge research fields. This technique allows the production of nonwoven micro/nanofibrous materials, including polymers, ceramics and metals, with a wide range of morphologies and functionalities. The highly porous electrospun scaffolds are ideal for biomedical applications, in particular for tissue engineering and drug delivery of biologically active compounds. In this review, we summarize the works on electrospun micro/nanofibers for biomedical applications carried out by research groups from Latin American countries. Studies are mainly focused on nanofibrous polymeric systems for drug delivery of therepeutic and bioactive agents, tissue engineering scaffolds and sensors, as well as other biomedical applications.; Fil: Caracciolo, Pablo Christian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina;; Fil: Cortez Tornello, Pablo Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico - CONICET - Mar del Plata. Instituto de Investigación en Ciencia y Tecnología de Materiales (i); Argentina;; Fil: Montini Ballarin...