Últimos itens adicionados do Acervo: Universidade Européia

Universidade privada em Madrid, Espanha

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Anticancer and antiangiogenic activity of surfactant-free nanoparticles based on self-assembled polymeric derivatives of vitamin e: Structure-activity relationship

Palao Suay, R.; Aguilar, M. R.; Parra Ruiz, F. J.; Fernández Gutiérrez, M.; Parra, J.; Sánchez Rodríguez, C.; Sanz Fernández, Ricardo; Rodrigáñez, L.; Román, J. S.
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Artigo de Revista Científica
ENG
α-Tocopheryl succinate (α-TOS) is a well-known mitochondrially targeted anticancer compound, however, it is highly hydrophobic and toxic. In order to improve its activity and reduce its toxicity, new surfactant-free biologically active nanoparticles (NP) were synthesized. A methacrylic derivative of α-TOS (MTOS) was prepared and incorporated in amphiphilic pseudoblock copolymers when copolymerized with N-vinylpyrrolidone (VP) by free radical polymerization (poly(VP-co-MTOS)). The selected poly(VP-co-MTOS) copolymers formed surfactant-free NP by nanoprecipitation with sizes between 96 and 220 nm and narrow size distribution, and the in vitro biological activity was tested. In order to understand the structure-activity relationship three other methacrylic monomers were synthesized and characterized: MVE did not have the succinate group, SPHY did not have the chromanol ring, and MPHY did not have both the succinate group and the chromanol ring.

Strenuous endurance exercise and right ventricular systolic function: no evidence of long-term sequelae

Sanchís-Gomar, Fabián; Garatachea, Nuria; Catalán, P.; López, M.; Lucía Mulas, Alejandro; Serrano-Ostáriz, Enrique
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Artigo de Revista Científica
ENG
Letter to the editor.

Exome sequencing of three cases of familial exceptional longevity

Cash, T. P.; Pita, G.; Domínguez, O.; Alonso, M. R.; Moreno, L. T.; Borrás, Carmen; Rodríguez Mañas, Leocadio; Santiago Dorrego, Catalina; Garatachea, Nuria; Lucía Mulas, Alejandro; Avellana, Juan A.; Viña, José; González Neira, Anna; Serrano, Man
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Artigo de Revista Científica
ENG
Exceptional longevity (EL) is a rare phenotype that can cluster in families, and co-segregation of genetic variation in these families may point to candidate genes that could contribute to extended lifespan. In this study, for the first time, we have sequenced a total of seven exomes from exceptionally long-lived siblings (probands ≥ 103 years and at least one sibling ≥ 97 years) that come from three separate families. We have focused on rare functional variants (RFVs) which have ≤ 1% minor allele frequency according to databases and that are likely to alter gene product function. Based on this, we have identified one candidate longevity gene carrying RFVs in all three families, APOB. Interestingly, APOB is a component of lipoprotein particles together with APOE, and variants in the genes encoding these two proteins have been previously associated with human longevity.

Muscle function and body composition profile in adolescents withrestrictive anorexia nervosa: does resistance training help?

Fernández del Valle, María; Larumbe Zabala, Eneko; Morandé Lavín, Gonzalo; Pérez Ruiz, Margarita
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Artigo de Revista Científica
ENG
The aim of this study was to analyze the effects of short-term resistance training on the body composition profile and muscle function in a group of Anorexia Nervosa restricting type (AN-R) patients. The sample consisted of AN-R female adolescents (12.8 ± 0.6 years) allocated into the control and intervention groups (n¼18 each). Body composition and relative strength were assessed at baseline, after 8 weeks and 4 weeks following the intervention. Body mass index (BMI) increased throughout the study (p = 0.011). Significant skeletal muscle mass (SMM) gains were found in the intervention group (p = 0.045, d = 0.6) that correlated to the change in BMI (r = 0.51, p < 0.031). Meanwhile, fat mass (FM) gains were significant in the control group (p = 0.047, d = 0.6) and correlated (r > 0.60) with change in BMI in both the groups. Significant relative strength increases (p < 0.001) were found in the intervention group and were sustained over time.

Assessment of upper arm anthropometric changes on anorexia nervosa patients after resistance training

Fernández del Valle, María; Larumbe Zabala, Eneko; Villaseñor Montarroso, Ángel; Murdock, Victoria; Pérez Ruiz, Margarita
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Conferência ou Objeto de Conferência
ENG

Exercise and pregnancy

Barakat, Rubén; Lucía Mulas, Alejandro; Ruiz, Jonatan R.
Fonte: John Wiley & Sons Publicador: John Wiley & Sons
Tipo: Parte de Livro
ENG

Transmural crossover of myocardial fibers underneath the pulmonary valve: implication for ablation of idiopathic ventricular outflow tract tachycardias

Murillo, M.; Cabrera Rodríguez, José Ángel; Pizarro, Gonzalo; Fuertes Suárez, Beatriz; González, E.; Sánchez-Quintana, Damian
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Artigo de Revista Científica
ENG

Limitation of Remote Laboratory in Control Education

Aliane, Nourdine; Vargas Pastor, Rafael; Vivas Mariscal, Gonzalo
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Artigo de Revista Científica
ENG
Remote laboratories showed significant progress during last years. Their integration in engineering education had their justification in solving many logistic problems inherent to conventional labs. In control engineering education, shifting from hands-on experience to a remote experimentation modifies completely the learning environment, and the factors that could compromise the effectiveness of learning outcomes should be considered carefully. This short paper discusses a number of pedagogical limitations intrinsic to remote experimentation in control engineering education.

Strenuous exercise worse than sedentarism?

Sanchís-Gomar, Fabián; Pareja Galeano, Helios; Santos-Lozano, Alejandro; Fiuza Luces, María del Carmen; Garatachea, Nuria; Lucía Mulas, Alejandro
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Artigo de Revista Científica
ENG
Letter

Sistemas de Alerta y Registro de Infracciones de Tráfico

Aliane, Nourdine; Fernández, J.; Bemposta Rosende, Sergio
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Conferência ou Objeto de Conferência
SPA

SACAT: Un sistema de ayuda a la conducción y asistencia en caso de accidentes

Fernñandez, J.; Aliane, Nourdine; Mata Ortega, Mario; Bemposta Rosende, Sergio
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Conferência ou Objeto de Conferência
SPA

Male urethritis caused by neisseria gonorrhoeae: resistance patterns have changed in a metropolitan sanitary area of madrid

García Tello, Ana; Cacho, J.; García Cañas, A.; González Torralba, A.; Torres, G.; Angulo Cuesta, Javier
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Artigo de Revista Científica
ENG

SACAT: Una Plataforma Experimental para la Asistencia a la Conducción

Fernández, J.; Aliane, Nourdine; Mata Ortega, Mario; Bemposta Rosende, Sergio; Egido García, Verónica
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Conferência ou Objeto de Conferência
SPA

Descriptive analysis of a series of urinary tuberculosis with emphasis on diagnostic and therapeutic data

García Tello, Ana; Cacho, J.
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Artigo de Revista Científica
ENG

The close anatomical relationship between the coronary arteries and the myocardial infundibulum of the right ventricle: a potential cause of coronary injury after catheter ablation of RVOT tachycardia

Murillo, M.; Cabrera Rodríguez, José Ángel; Pizarro, Gonzalo
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Artigo de Revista Científica
ENG

The anatomic relationship between the right and left ventricular outflow tracts: its relevance in catheter ablation

Cabrera Rodríguez, José Ángel; Murillo, M.; Pizarro, Gonzalo
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Artigo de Revista Científica
ENG

Structured remote laboratory development

Pastor, R.; Sánchez, D.; Aliane, Nourdine; Hernández, R.; Mariscal, G.; Robles Gómez, A.; Caminero, A.; Ros, S.; Tawfik, M.; Cristóbal, E. S.; Diaz, G.; Castro, M.
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Conferência ou Objeto de Conferência
SPA
The use of remote laboratories has become a common technique in universities to provide educational services related to engineering. However, the development efforts of these laboratories have not been contemplated in a structured way, with no specific methodologies that allow the reuse of such laboratories or parts thereof. This problem of structured and methodological development is associated with a number of disadvantages which imply that the development of new labs or their integration with other services is a complex task. This paper shows how this goal can be achieved using RELATED (REmote LAboratories exTendED). It is shown the development model proposed by this methodology, as well as the services provided by this development framework. The article shows an example of application of this methodology, using a magnetic levitation system, which is prepared for “on-site” experiences. From this laboratory, and following specific methodological steps, is shown as is possible to reuse developed code and provide a set of remote experiments for the magnetic levitation system.

Umbilical KeyPort bilateral laparoscopic orchiectomy in patient with complete androgen insensitivity syndrome

Andrade, F. P.; Angulo Cuesta, Javier
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Artigo de Revista Científica
ENG

Sistema de acceso a la información basado en conceptos utilizando Freebase en español-inglés sobre el dominio médico y turístico

Muñoz Gil, Rafael; Aparicio Galisteo, Fernando; De Buenaga Rodríguez, Manuel
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Artigo de Revista Científica
SPA
En este artículo presentamos una herramienta de acceso a la información, basado en los conceptos, enfocada tanto a textos médicos como turísticos. Usando técnicas para el marcado de entidades reconocidas, el sistema permite extraer conceptos relevantes para aportar más información sobre ellos utilizando bases de conocimiento colaborativas y ontologías. Componentes especialmente interesantes para el desarrollo del sistema son Freebase, una gran base de conocimiento colaborativa, además de recursos formales como MedlinePlus y PubMed. La arquitectura del sistema ha sido construida pensando en términos de escalabilidad, para constituir una gran plataforma de integración de información, con los siguientes objetivos: permitir la integración de diferentes técnicas de procesamiento de lenguaje natural y ampliar las fuentes desde las que se extrae información, así como facilitar la integración de nuevas interfaces de usuario.

Cistectomía radical laparoendoscópica con neovejiga íleal ortotópica a través de puerto único umbilical [ Laparoendoscopic Radical Cystectomy with Orthotopic Ileal Neobladder through Umbilical Single Port

Angulo Cuesta, Javier
Fonte: Universidade Européia Publicador: Universidade Européia
Tipo: Artigo de Revista Científica
ENG