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Tempo de resposta a tratamento antipsicótico na esquizofrenia de início recente: um estudo randomizado e controlado de 12 semanas; Time to response to antipsychotics in recent onset schizophrenia a randomized controlled 12-week trial

Kayo, Monica
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 16/12/2010 PT
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65.5%
INTRODUÇÃO: Acredita-se cada vez mais que o tempo para se observar a resposta ao antipsicótico é curto, sendo possível nas primeiras duas semanas já prever se o paciente responderá em 12 semanas. Entretanto, a maior parte das evidências que sustentam tal hipótese provém da análise de dados de estudos controlados duplo-cegos, que não definiam o conceito de início de ação de antipsicóticos, o que pode gerar uma certa confusão quanto às expectativas de resposta. Neste estudo, testamos se a ausência de melhora mínima de 20% da PANSS nas primeiras duas semanas correlacionava-se a ausência de resposta em 12 semanas. MÉTODOS: Foi feita a avaliação do tempo de resposta ao tratamento antipsicótico, utilizando o algoritmo de tratamento do IPAP, que recomenda o uso de monoterapia por 4 a 6 semanas, e troca por outro antipsicótico em caso de ausência de resposta. Os pacientes incluídos tinham esquizofrenia de início recente pelos critérios DSM-IV e foram aleatorizados para receber tratamento com antipsicótico de primeira geração (APG) ou de segunda geração (ASG). Foi considerada resposta ao tratamento a redução média de pelo menos 30% dos sintomas, em comparação com a PANSS inicial.Os pacientes foram avaliados pela PANSS a cada 2 semanas...

Therapy of Falciparum Malaria in Sub-Saharan Africa: from Molecule to Policy

Winstanley, Peter; Ward, Stephen; Snow, Robert; Breckenridge, Alasdair
Fonte: American Society for Microbiology Publicador: American Society for Microbiology
Tipo: Artigo de Revista Científica
Publicado em /07/2004 EN
Relevância na Pesquisa
45.4%
The burden of falciparum malaria remains as great as ever, and, as has probably always been the case, it is carried mainly by tropical Africa. Of the various means available for the control of malaria, the use of effective drugs remains the most important and is likely to remain so for a considerable time to come. Unfortunately, the extensive development of resistance by the parasite threatens the utility of most of the affordable classes of drug: the development of novel antimalarials has never been more urgently needed. Any attempt to understand the vast complexities of falciparum malaria in Africa requires an ability to think “from molecule to policy.” In consequence, the review ambitiously tries to examine the current pharmacopeia, the process by which new drugs are developed and the ways in which drugs are actually used, in both the formal and informal health sectors. The informal sector is particularly important in Africa, where around half of all antimalarial treatments are bought from informal outlets and taken at home without supervision by health care professionals: the potential impact of adherence on clinical outcome is discussed. Given that the full costs are carried by the patient in a large proportion of cases, the importance of drug affordability is explored. The review also discusses the splicing of new drugs into national policy. The various parameters that feed into deliberations on changes in drug policy are discussed.

Changing time and emotions

Geoffard, Pierre-Yves; Luchini, Stéphane
Fonte: The Royal Society Publicador: The Royal Society
Tipo: Artigo de Revista Científica
Publicado em 27/01/2010 EN
Relevância na Pesquisa
45.5%
In this paper, we consider that our experience of time (to come) depends on the emotions we feel when we imagine future pleasant or unpleasant events. A positive emotion such as relief or joy associated with a pleasant event that will happen in the future induces impatience. Impatience, in our context, implies that the experience of time up to the forthcoming event expands. A negative emotion such as grief or frustration associated with an unpleasant event that will happen in the future triggers anxiety. This will give the experience of time contraction. Time, therefore, is not exogeneously given to the individual and emotions, which link together events or situations, are a constitutive ingredient of the experience of time. Our theory can explain experimental evidence that people tend to prefer to perform painful actions earlier than pleasurable ones, contrary to the predictions yielded by the standard exponential discounting framework.

Self-reported barriers to colorectal cancer screening in a racially diverse, low-income study population

Quick, Benjamin W.; Hester, Christina M.; Young, Kristin L.; Greiner, K. Allen
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /04/2013 EN
Relevância na Pesquisa
45.4%
Colorectal cancer (CRC) screening is underutilized, especially in low income, high minority populations. We examined the effect test-specific barriers have on colonoscopy and fecal immunochemical test (FIT) completion, what rationales are given for non-completion, and what “switch” patterns exist when participants are allowed to switch from one test to another. Low income adults who were not up-to-date with CRC screening guidelines were recruited from safety-net clinics and offered colonoscopy or FIT (n=418). Follow up telephone surveys assessed test-specific barriers. Test completion was determined from patient medical records. For subjects who desired colonoscopy at baseline, finding a time to come in and transportation applied more to non-completers than completers (p = 0.001 and p < 0.001, respectively). For participants who initially wanted FIT, keeping track of cards, never putting stool on cards, and not remembering to mail cards back applied more to non-completers than completers (p = 0.003, p = 0.006, and p < 0.001, respectively). The most common rationale given for not completing screening was a desire for the other screening modality: 7% of patients who initially preferred screening by FIT completed colonoscopy, while 8% of patients who initially preferred screening by colonoscopy completed FIT. We conclude that test-specific barriers apply more to subjects who did not complete CRC screening. As a common rationale for test non-completion is a desire to receive a different screening modality...

Is Incretin-Based Therapy Ready for the Care of Hospitalized Patients With Type 2 Diabetes?: The time has come for GLP-1 receptor agonists!

Schwartz, Stanley; DeFronzo, Ralph A.
Fonte: American Diabetes Association Publicador: American Diabetes Association
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
45.45%
Significant data suggest that overt hyperglycemia, either observed with or without a prior diagnosis of diabetes, contributes to an increase in mortality and morbidity in hospitalized patients. In this regard, goal-directed insulin therapy has remained as the standard of care for achieving and maintaining glycemic control in hospitalized patients with critical and noncritical illness. As such, protocols to assist in the management of hyperglycemia in the inpatient setting have become commonplace in hospital settings. Clearly, insulin is a known entity, has been in clinical use for almost a century, and is effective. However, there are limitations to its use. Based on the observed mechanisms of action and efficacy, there has been a great interest in using incretin-based therapy with glucagon-like peptide-1 (GLP-1) receptor agonists instead of, or complementary to, an insulin-based approach to improve glycemic control in hospitalized, severely ill diabetic patients. To provide an understanding of both sides of the argument, we provide a discussion of this topic as part of this two-part point-counterpoint narrative. In this point narrative as presented below, Drs. Schwartz and DeFronzo provide an opinion that now is the time to consider GLP-1 receptor agonists as a logical consideration for inpatient glycemic control. It is important to note the recommendations they propose under “incretin-based approach” with these agents represent their opinion for use and...

Modeling Potential Time to Event Data with Competing Risks

Li, Liang; Hu, Bo; Kattan, Michael W.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
45.45%
Patients receiving radical prostatectomy are at risk of metastasis or prostate cancer related death, and often need repeated clinical evaluations to determine whether additional adjuvant or salvage therapies are needed. Since the prostate cancer is a slowly progressing disease, and these additional therapies come with significant side effects, it is important for clinical decision making purposes to estimate a patient’s risk of cancer metastasis, in the presence of a competing risk by death, under the hypothetical condition that the patient does not receive any additional therapy. In observational studies, patients may receive additional therapy by choice; the time to metastasis without any therapy is often a potential outcome and not always observed. We study the competing risks model of Fine and Gray (1999) with adjustment for treatment choice by inverse probability censoring weighting (IPCW). The model can be fit using standard software for partial likelihood with double IPCW weights. The proposed methodology is used in a prostate cancer study to predict the post-prostatectomy cumulative incidence probability of cancer metastasis without additional adjuvant or salvage therapies.

ROThAr: real-time on-line traffic assignment with load estimation

Saber, Takfarinas; Ventresque, Anthony; Murphy, John
Fonte: IEEE Computer Society Publicador: IEEE Computer Society
Tipo: info:eu-repo/semantics/conferenceObject; all_ul_research; ul_published_reviewed
ENG
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peer-reviewed; More and more drivers use on-board units to help them navigate in the increasing urbanised environment they live and work in. These system (e.g., routing applications on smart phones) are now very often on-line, and use information from the traffic situation (e.g., accidents, congestion) to get the best route. We can now envisage a world where all trips are assigned and updated by such an on-line system, making the best routing decisions based on traffic conditions. The problem is that current systems consider only ‘local’ elements (e.g., driver preference and current traffic condition) and do not make routing decisions from a global perspective. This can lead to a lot of similar routing assignments that could lead to further traffic congestion. The objective of the next generation on-line navigation systems is then to come up with a ‘smart’, real-time route assignment, which balances the load between the different road segments and offers the best quality to the drivers. However, every routing decision made has an impact on the traffic conditions (one more vehicle on the road segments selected) and computing the load induced by the trips is a computationally heavy problem. This paper addresses this question of real-time on-line traffic assignment...

A radical alternative?: a re-evaluation of Chantal Mouffe’s radical democratic approach.

Skrzypiec, Leah
Fonte: Universidade de Adelaide Publicador: Universidade de Adelaide
Tipo: Tese de Doutorado
Publicado em //2011
Relevância na Pesquisa
45.4%
The catalyst for this thesis is the current debate addressing the nature and practice of liberal democracies. Many critics have argued that liberal democracies are failing their constituents, and in order to revitalise the key features of “robust” democracies, a number of alternatives have been proposed. Chantal Mouffe’s radical democratic approach offers one such alternative. Mouffe has written extensively on this subject and is considered an eminent proponent of a left, democratic, alternative and it is her body of work that I take as my explicit focus. This thesis examines to what degree Mouffe’s alternative can be considered radical. There are three important elements to this evaluation, all of which relate to the different definitions of the term. Specifically, these criteria are embodied in the following questions: “How different to the other alternatives is Mouffe’s approach?”; “How left is it?”; and “How democratic is it?”. While it is clear that some of Mouffe’s work has progressive, disruptive, democratic, and therefore “radical” elements, this thesis argues that this radicalness does not reach its full potential. The lacunae in Mouffe’s work, which relate to a lack of detail and theoretical clarification on many important concepts...

Representing functional data in reproducing Kernel Hilbert spaces with applications to clustering, classification and time series problems

González Hernández, Javier
Fonte: Universidade Carlos III de Madrid Publicador: Universidade Carlos III de Madrid
Tipo: info:eu-repo/semantics/doctoralThesis; info:eu-repo/semantics/doctoralThesis Formato: application/octet-stream; application/octet-stream; application/pdf
ENG
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45.45%
In modern data analysis areas such as Image Analysis, Chemometrics or Information Retrieval the raw data are often complex and their representation in Euclidean spaces is not straightforward. However most statistical data analysis techniques are designed to deal with points in Euclidean spaces and hence a representation of the data in some Euclidean coordinate system is always required as a previous step to apply multivariate analysis techniques. This process is crucial to guarantee the success of the data analysis methodologies and will be a core contribution of this thesis. In this work we will develop general data representation techniques in the framework of Functional Data Analysis (FDA) for classification and clustering problems. In Chapter 1 we motivate the problems to solve, describe the roadmap of the contributions and set up the notation of this work. In Chapter 2 we review some aspects concerning Reproducing Kernel Hilbert Spaces (RKHSs), Regularization Theory Integral Operators, Support Vector Machines and Kernel Combinations. In Chapter 3 we propose a new methodology to obtain finite-dimensional representations of functional data. The key idea is to consider each functional curve as a point in a general function space and then project these points onto a Reproducing Kernel Hilbert Space (RKHS) with the aid of Regularization theory. We will describe the projection methods...

Air Power and Trans-National Terrorism: the Possibilities, Advantages and Limits to Using Australian Air Power in the 'War on Terror'.

Gray-Murphy, Sam
Fonte: Universidade Nacional da Austrália Publicador: Universidade Nacional da Austrália
Tipo: Relatório
Relevância na Pesquisa
45.4%
Although terrorism is by no means a new phenomenon, contemporary trans-national terrorist groups are an increasingly prominent source of threat to Australians and Australian interests around the world. Terrorism is not primarily a military problem, yet the severity of the contemporary threat calls for the Australian Defence Force (ADF) to assume a greater share of the counter-terrorism burden. The fight against trans-national terrorism will not be easy; it promises to be long and will involve all elements of national power, including air power. Air Power has the capacity to make a significant contribution to Australia's counter-terrorism efforts and effectively exploiting such a vital 'force enhancer' will benefit Australian national security. Predicting the future strategic environment is an inherently demanding task that seldom produces accurate forecasts. Whilst it is tempting to suggest that low-intensity conflicts and counter-terrorism operations will be the warfighting way of the future, one cannot discount the ever-present, albeit unlikely, threat of a high-impact, conventional military contingency. Australia's involvement in the so-called 'War on Terror' should not become the Royal Australian Air Force's (RAAF) primary strategic focus. However...

Interactive Video Instruction: A Training Tool Whose Time Has Come

Kavanaugh, Raphael R.; Ninemeier, Jack D.
Fonte: FIU Digital Commons Publicador: FIU Digital Commons
Tipo: Artigo de Revista Científica Formato: application/pdf
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Training employees in the hospitality industry to meet guests' expectations is a critical element to success. Unfortunately, this element is often ignored. This article explores an exciting training method (interactive video) and its advantages over other training approaches.

Kenya : A Policy Agenda to Restore Growth

World Bank
Fonte: Washington, DC Publicador: Washington, DC
Tipo: Economic & Sector Work :: Country Economic Memorandum; Economic & Sector Work
ENGLISH; EN_US
Relevância na Pesquisa
45.4%
This Country Economic Memorandum (CEM) - the first since 1995 - is a contribution to the government's economic recovery strategy, and to its Poverty Reduction Strategy Paper (PRSP), being finalized. It examines Kenya's economic performance during the past decade, and identifies the structural weaknesses that have contributed to the decline in productivity, and the competitiveness of the economy during this period. It also recommends policy, and institutional reforms to revitalize economic growth, and to reduce poverty. The message from the CEM is a sober one: increased poverty is the legacy from almost two decades of slow growth; and, the burden of disease, particularly malaria and HIV/AIDS will constrain growth in the years to come. However, given the improved economic policy environment, the potential for economic growth is significantly better than the poor performance in the 1990s would indicate. But even in our high-case scenario Kenya is unlikely to reach the Millennium Development Goal of cutting in half by 2015 the proportion of Kenyans living in poverty in 1990. Reducing poverty will remain a tremendous challenge. The CEM is organized into six chapters. Chapter 1 reviews recent economic developments...

I want to be a doctor

Balmaceda Escobar, Alexandra
Fonte: Medicina Narrativa Publicador: Medicina Narrativa
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; Artículo Formato: application/pdf
SPA
Relevância na Pesquisa
45.5%
Do you feel me? Sometimes I go throughout the day thinking that everything is just as it should be and then I think ... No. We all have a purpose in life, whether we choose to fulfill that purpose or not is up to us. Today I began to think about the day I had made a decision to come to Colombia to study medicine. And even before I had made a decision to become a doctor and think what happened in my life that took me to the day where I said for the first time ¨I want to be a doctor¨. Is there a purpose that I have to fulfill in my life? I hope there is ...because if not what is there to living really. We have 24 hours a day where 8 of those 24 are spent sleeping. The rest is spent ¨living¨ our lives. There are many things that I would like to do right now. But there are always things that stand in the way and stop us from doing what our hearts tell us to. Is that a good thing? What would it be like if we lived in a world where hearts ruled over mind. Would it be a happier place, would we have more love, sadness, joy. Or maybe medicine came to my life for a reason... to meet someone, to meet many people, to help people, to bring a smile to a strangers face, to understand me. All of these could be reasons why medicine came in to my life. And now as a student of medicine I have discovered many of those reasons. Some more than others. Without a doubt I can now say...

Things to come: postmodern digital knowledge management and medical informatics.

Matheson, N W
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em //1995 EN
Relevância na Pesquisa
45.5%
The overarching informatics grand challenge facing society is the creation of knowledge management systems that can acquire, conserve, organize, retrieve, display, and distribute what is known today in a manner that informs and educates, facilitates the discovery and creation of new knowledge, and contributes to the health and welfare of the planet. At one time the private, national, and university libraries of the world collectively constituted the memory of society's intellectual history. In the future, these new digital knowledge management systems will constitute human memory in its entirety. The current model of multiple local collections of duplicated resources will give way to specialized sole-source servers. In this new environment all scholarly scientific knowledge should be public domain knowledge: managed by scientists, organized for the advancement of knowledge, and readily available to all. Over the next decade, the challenge for the field of medical informatics and for the libraries that serve as the continuous memory for the biomedical sciences will be to come together to form a new organization that will lead to the development of postmodern digital knowledge management systems for medicine. These systems will form a portion of the evolving world brain of the 21st century.

Injury prevention: the time has come.

Cushman, R
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em 01/01/1995 EN
Relevância na Pesquisa
45.55%
Although cancer, heart disease and stroke occupy much of society's attention to health matters, injuries account for more potential years of life lost before age 65 than all these diseases combined. The time has come to set the record straight and to give injury its rightful place on the health policy agenda. Contrary to popular belief, most injuries are no accident. More than 90% of injuries are both predictable and preventable. Injury prevention, a multidisciplinary effort, is coming of age in Canada. Education alone is not enough. New technology, innovative approaches to safety education and the mobilization of community resources can help to change behaviour and legislation to decrease the risk of injury. Physicians have an important role to play in this process.

Marxist psychology: a research paradigm whose time has come

Elhammoumi,Mohamed
Fonte: Programa de Pós-Graduação em Psicologia, Pontifícia Universidade Católica de Campinas Publicador: Programa de Pós-Graduação em Psicologia, Pontifícia Universidade Católica de Campinas
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/03/2012 EN
Relevância na Pesquisa
45.55%
This paper seeks to retrieve Marx's ideas about the development of psychology. It offers historical perspectives on different attempts to create a Marxist psychology that shed light on its scope and trajectory. According to Marx, concrete social and material real life play a key role in the development of human psychological functions. Later, Vygotsky, Wallon, Politzer, Leontiev, Luria, Sève among others built on Marx's ideas. These psychologists suggested that individual psychological functions are formed and shaped in concrete, cultural, social, historical circumstances, and pictured an organizing, creative force driving individual activity (instead of behavior). Marxist psychology is the study of the social individual within social relations of production. In a Marxist sense, the emphasis is placed on production, both material and social as the essence of social relations. Hence, psychology cannot be dealt with in an abstract, private and individual manner as the capitalist mode of production would want, but must be seen in terms of the social individual that is formed, structured, and shaped within the social relations of a production framework. In this context, the social production of the individual (as developed in Marx's Die Grundrisse) signifies social relations between people connected with concrete common real social conditions and material production. Production...

O tempo do trabalho: o tempo-devir frente ao tempo espacializado; The time of work: time-to-come in face of spacialized time

Zarifian, Philippe
Fonte: Universidade de São Paulo. Faculdade de Filosofia, Letras e Ciências Humanas Publicador: Universidade de São Paulo. Faculdade de Filosofia, Letras e Ciências Humanas
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; ; ; Formato: application/pdf
Publicado em 01/10/2002 POR
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95.71%
Este artigo investiga a questão da produtividade do trabalho sob o prisma da interioridade recíproca entre o tempo e o trabalho. Essa interioridade revela, no plano conceitual, o enfrentamento entre duas concepções do tempo: o tempo espacializado, quantitativo e físico, medido pela sucessão de instantes materializados no relógio; e o tempo-devir, qualitativo e psicológico, entendido como duração, na qual há um ímpeto permanente da totalidade do passado em direção ao futuro. Esses tempos apresentam frente ao trabalho modos diferentes de manifestação social: o tempo espacializado se manifesta como disciplina e regulação dos atos de trabalho e o tempo-devir como mobilização da experiência passada e antecipação do porvir. Mostra-se, finalmente, que, embora estejam necessariamente vinculados ao trabalho, sendo ambos produtos sociais efetivos, existe um desequilíbrio claro na manifestação dos dois tipos de tempo.; This article investigates the subject of work productivity through the optics of the reciprocal interiority between time and work. This interiority reveals, in the conceptual plane, the confrontation of two time concepts: the spacialized time, quantitative and physic, measured by the instants successions materialized on the clock; and the time-to-come...

PARAMETERS SELECTION OF TIME-INTENSITY CURVES IN SUGAR CANE SPIRITS AGED AND NON-AGED IN OAK BARRELS (Quercus alba L.) BY STEPWISE DISCRIMINANT AND REGRESSION ANALYSIS; SELEÇÃO DE PARÂMETROS DE CURVAS TEMPO-INTENSIDADE DE AGUARDENTES DE CANA SEM ENVELHECIMENTO E ENVELHECIDAS EM TONÉIS DE CARVALHO (Quercus alba L.) POR ANÁLISE DISCRIMINANTE POR PASSOS E ANÁLISE DE CORRELAÇÃO

CARDELLO, HELENA MARIA ANDRÉ BOLINI; Faculdade de Ciências Farmacêuticas, UNESP; FARIA, JOÃO BOSCO; Faculdade de Ciências Farmacêuticas, UNESP
Fonte: UFPR Publicador: UFPR
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; Formato: application/pdf
Publicado em 01/04/2009 POR
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45.51%
It was verified the possibility to reduce a number of parameters necessary for the time-intensity-analysis in the sensorial characteristics of aged sugar cane spirits (“cachaça”). It was made a statistical study of all possible parameters, which were submitted to stepwise discriminant and regression analysis. It was sampled aged “cachaças” in oak barrels at zero, 12, 24, 36 and 48 months and six commercial brands, being three aged and three not, for the evaluation of sweetness, aggressive alcoholic taste and wood taste. The parameters obtained from each curve were: time to reach the maximal intensity (TImax), time in which the maximal intensity begins to decline (Td), duration time of the maximal intensity (Plato), total area under the curve (Area), total duration time of incentive (Ttot) e maximal intensity noticed (Imax). The results suggested that the parameters Imax and Plato could be eliminated in the  time-intensity analysis of the sweet taste and wood taste, respectively without changing the final results of the analysis.; Verificou-se a possibilidade de reduzir o número de parâmetros necessários em análise tempo intensidade (T-I) de características sensoriais de aguardente de cana...

It’s time to introduce another word to the lexicon of EU commentary: “Gretention”

Price, Edward
Fonte: Blog post from London School of Economics & Political Science Publicador: Blog post from London School of Economics & Political Science
Tipo: Website; NonPeerReviewed Formato: application/pdf
Publicado em 06/11/2012 EN; EN
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45.45%
Greece’s exit from the Eurozone, widely predicted earlier this year as being almost inevitable, has not come to pass. Edward Price argues that “Grexit“ has largely been avoided by the friction of the EU’s institutions, and that the slow decision making that has characterised the eurozone crisis has given countries time to form new governments and adopt new positions on the future of the single currency. Now, he writes, we must explain “Gretention”, or why Greece did not leave the euro in 2012.

Perinatal factors in students admitted to the university of the West Indies data from the jamaican perinatal study

Foster-Williams,K; Younger,N; Brown-Dennis,A; Ashley,DE; McCaw-Binns,A; Samms-Vaughan,M; Williams,W; Serjeant,GR
Fonte: West Indian Medical Journal Publicador: West Indian Medical Journal
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/2010 EN
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45.45%
OBJECTIVE: To compare perinatal and social factors in students admitted to The University of the West Indies (UWI), Kingston, Jamaica, at age 18 years with those in the rest of the Jamaican Perinatal Cohort. METHODS: The Jamaican Perinatal Survey recorded demographic and perinatal details in 10 527 or 97% of births in Jamaica in September and October 1986. Eighteen years later, 140 of these were admitted to the UWI in Kingston, Jamaica. The perinatal features of these UWI students have been compared with the rest ofthe Perinatal Survey Cohort. RESULTS: Mothers of UWI students were older (p < 0.001), more likely to be married at the time of birth (p < 0.001), had earlier and more complete antenatal care (p < 0.05) and greater educational achievement at time of pregnancy (p < 0.001). These mothers of UWI students were also more likely to have diabetes (p < 0.01), operative deliveries (p < 0.01) and to attend private hospitals (p < 0.01). The UWI students had fewer siblings by their mothers (p < 0.05), were less likely to be low birthweight babies (p = 0.035) and more likely to be full term (37-42 weeks) than lower gestational age (p = 0.005). Differences in Apgar scores did not reach statistical significance. CONCLUSIONS: The students of the University of the West Indies were more likely to come from smaller families with features indicative of a better quality of life. They were also of higher birthweight and tended to be full term. The lack of association of Apgar scores with educational attainment is noteworthy.