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Molecular biology and evolution of beta-globin genes in monotremes / Mi-Hye Lee.; Molecular biology and evolution of beta-globin genese in monotremes

Lee, Mi-Hye
Fonte: Universidade de Adelaide Publicador: Universidade de Adelaide
Tipo: Tese de Doutorado Formato: 93916 bytes; application/pdf
Publicado em //1997 EN
Relevância na Pesquisa
27.43%
The evolutionary relationships of the beta-like globin genes were studied by applying maximum parsimony methods to aligned DNA sequences.; Thesis (Ph.D.)--University of Adelaide, Dept. of Genetics, 1998?; Erratum pasted on front fly-leaf.; Bibliography: leaves 180-202.; xvii, 220 leaves : ill. (some col.) ; 30 cm.; Title page, contents and abstract only. The complete thesis in print form is available from the University Library.

Parathyroid glands in marsupials and monotremes / y Julie Irene Haynes.

Haynes, Julie Irene
Fonte: Universidade de Adelaide Publicador: Universidade de Adelaide
Tipo: Tese de Doutorado Formato: 253470 bytes; application/pdf
Publicado em //1997 EN
Relevância na Pesquisa
27.13%
Thesis (Ph.D.A)--University of Adelaide, Dept. of Anatomical Sciences, 1998?; Addendum pasted onto front end-paper.; Bibliography: leaves 214-226.; v, 227, [7] leaves, [71] leaves of plates : ill. (some col.) ; 30 cm.; Title page, contents and abstract only. The complete thesis in print form is available from the University Library.

Evolution of mammalian sex chromosomes and sex determination genes: insights from monotremes.

Toledo-Flores, Deborah Fernanda
Fonte: Universidade de Adelaide Publicador: Universidade de Adelaide
Tipo: Tese de Doutorado
Publicado em //2015
Relevância na Pesquisa
37.91%
Genetic sex determination systems are generally based on the presence of differentiated sex chromosomes. Birds have a ZZ/ZW sex chromosome system in which males are ZZ and females ZW, whereas mammals have an XX/XY system with males being XY and females XX. Monotremes have an extraordinary sex chromosome system that consists of multiple sex chromosomes: 5X5Y in platypus and 5X4Y in echidna. Intriguingly, the monotreme sex chromosomes show extensive homology to the bird ZW and not to the therian XY. However, sex determination in monotremes is still a mystery; the Y-specific Sry gene that triggers male sex determination in therian mammals is absent and so far very few genes have been identified on Y chromosomes in monotremes. To gain more insights into the gene content of Y-chromosomes and to identify potential sex determination genes in the platypus a collaborative large scale transcriptomic approach led to the identification of new male specific genes including the anti-Muellerian hormone AMH that I mapped to Y₅, this makes Amhy an exciting new candidate for sex determination in monotremes. Platypus chromosome 6 is largely homologous to the therian X and therefore it represents the therian proto sex chromosome. In addition, this autosome features a large heteromorphic nucleolus organizer region (NOR) and associates with the sex chromosomes during male meiosis (Casey and Daish personal communication). I investigated chromosome 6 heteromorphism in both sexes and found a number of sex-specific characteristics related to the extent of the NOR heteromorphism...