Página 1 dos resultados de 1439 itens digitais encontrados em 0.011 segundos

Incidência de doenças e necessidade de controle em cultivo protegido de videira; Incidence of diseases and needs of control in overhead covered grapes

Chavarria, Geraldo; Santos, Henrique Pessoa dos; Sônego, Olavo Roberto; Marodin, Gilmar Arduino Bettio; Bergamaschi, Homero; Cardoso, Loana Silveira
Fonte: Universidade Federal do Rio Grande do Sul Publicador: Universidade Federal do Rio Grande do Sul
Tipo: Artigo de Revista Científica Formato: application/pdf
POR
Relevância na Pesquisa
56.1%
O cultivo protegido de videira no Brasil tem-se expandido, em área, visando principalmente à diminuição de danos por adversidades climáticas sobre a produção e a maturação das uvas. Entretanto, não se dispõe de informações sobre o microclima e as necessidades de controle fitossanitário que são impostas por essa tecnologia, as quais constituem os objetivos deste trabalho. O experimento foi instalado no ciclo 2005-2006, em Flores da Cunha-RS, em um vinhedo de ‘Moscato Giallo’, conduzido em “Y”, com cobertura plástica impermeável (160μm), em 12 fileiras com 35m, deixando-se 5 fileiras sem cobertura (controle). Em ambas áreas, avaliou-se o microclima quanto à presença de água livre (registro visual), temperatura (T), umidade relativa (UR) do ar, radiação fotossinteticamente ativa (RFA) e velocidade do vento (VV) próximos ao dossel vegetativo e aos cachos. Na área coberta, foram aplicados fungicidas quando necessário, enquanto na área descoberta foram realizadas aplicações por calendário. Durante a floração e a maturação, avaliaram-se a incidência e a severidade de míldio (Plasmopara viticola), oídio (Uncinula necator), podridão-cinzentada- uva (Botrytis cinerea), podridão-da-uva-madura (Glomerella cingulata) e podridão ácida (leveduras imperfeitas e leveduras esporógenas). A cobertura plástica aumentou a temperatura diurna próxima ao dossel vegetativo...

Fungal microbiota isolated from healthy pig skin; Microbiota fúngica isolada da pele de suínos sadios

Carregaro, Fabiano Bonfim; Spanamberg, Andréia; Sanches, Edna Maria Cavallini; Argenta, Juliana Siqueira; Pereira, Daniela Isabel Brayer; Zanette, Regis Adriel; Santúrio, Jânio Morais; Barcellos, David Emilio Santos Neves de; Ferreiro, Laerte
Fonte: Universidade Federal do Rio Grande do Sul Publicador: Universidade Federal do Rio Grande do Sul
Tipo: Artigo de Revista Científica Formato: application/pdf
POR
Relevância na Pesquisa
46.16%
Background: Researches have been developed to observe the normal microbiota of different animal species. This subject is of major importance for the control of potential infection risks. Fungi can be found in various substrates, foodstuffs (cereals, meat, milk, vegetables) and also in the skin, mucosae, respiratory and gastrointestinal tracts of animals. With the dissemination of immunosuppressive diseases in swine herds over the last years, the number of concomitant diseases caused by opportunist microorganisms is gradually increasing in literature. The objective of this study was to determine the microbiota of pig skin with no apparent lesions. Materials, Methods and Results: A number of 261 pigs from 11 swine farms located in six municipalities of the State of Rio Grande do Sul, in Southern Brazil, were used for the study, in the period from April 2005 to April 2006. After being cleaned with water and 70% ethanol, skin samples were collected by friction of circular and sterile hair brushes against the posterior ventral region of the animals, on an area of no more than 10 cm. After sample collection, the brushes were wrapped with the same aluminium foil used in the sterilization process. Within the next 24 hours, the material was streaked onto agar and incubated at 25°C to 30ºC for up to four weeks. Micromorphology was used for mold identification purposes...

Immunogenetic profiling to predict risk of invasive fungal diseases : where are we now?

Cunha, Cristina; Aversa, Franco; Bistoni, Giovanni; Casagrande, Andrea; Rodrigues, Fernando José dos Santos; Romani, Luigina; Carvalho, Agostinho
Fonte: Informa Healthcare Publicador: Informa Healthcare
Tipo: Artigo de Revista Científica
Publicado em //2011 ENG
Relevância na Pesquisa
56.25%
Invasive fungal diseases remain nowadays life-threatening conditions affecting multiple clinical settings. The onset of these diseases is dependent on numerous factors, of which the "immunocompromised" phenotype of the patients is the more often acknowledged. However, and despite comparable immune dysfunction, not all patients are ultimately susceptible to disease, suggesting that additional risk factors, likely of genetic nature, may also be important. In the last years, genetic variants in several immune-related genes have also been proposed as major determinants of the susceptibility pattern of high-risk patients to invasive fungal diseases. Altogether, these findings highlighted the crucial significance of the individual genetic make-up in defining susceptibility to infection, providing a compelling rationale for the introduction of the immunogenetic profile as a risk prediction measure that may ultimately help to guide clinicians in the use of prophylaxis and preemptive fungal therapy in high-risk patients.; Ricerca sulla Fibrosi Cistica (Project number FFC#21/2010); Fundação para a Ciência e a Tecnologia (FCT) SFRH/BD/65962/2009, SFRH/BPD/46292/2008

DAMP signaling in fungal infections and diseases

Cunha, Cristina; Carvalho, Agostinho; Esposito, Antonella; Bistoni, Francesco; Romani, Luigina
Fonte: Frontiers Research Foundation Publicador: Frontiers Research Foundation
Tipo: Artigo de Revista Científica
Publicado em /09/2012 ENG
Relevância na Pesquisa
56.38%
Fungal infections and diseases predominantly affect patients with deregulated immunity. Compelling experimental and clinical evidence indicate that severe fungal diseases belong to the spectrum of fungus-related inflammatory diseases. Some degree of inflammation is required for protection during the transitional response occurring temporally between the rapid innate and slower adaptive response. However, progressive inflammation worsens disease and ultimately prevents pathogen eradication. The challenge now is to elucidate cellular and molecular pathways distinguishing protective vs. pathogenic inflammation to fungi. In addition to fungal ligands of pattern recognition receptors (pathogen-associated molecular patterns, PAMPs), several host-encoded proteins, the damage-associated molecular patterns (DAMPs), are released during tissue injury and activate innate recognition receptors. DAMPs have been shown to regulate inflammation in fungal diseases. The DAMP/receptor for advanced glycation end-products axis integrated with the PAMP/Toll-like receptors axis in the generation of the inflammatory response in experimental and clinical fungal pneumonia. These emerging themes better accommodate fungal pathogenesis in the face of high-level inflammation seen in several clinical settings and point to DAMP targeting as a novel immunomodulatory strategy in fungal diseases.; Supported by the Specific Targeted Research Project ALLFUN (FP7–HEALTH–2009 Contract number 260338) and the Italian Grant Application 2010 Fondazione per la Ricerca sulla Fibrosi Cistica (Research Project FFC#21/2010) with the contribution of funded Francesca Guadagnin...

How will climate change affect oil palm fungal diseases?

Paterson, R. R. M.; Sariah, M.; Lima, Nelson
Fonte: Elsevier; Butterworth Scientific Ltd. Publicador: Elsevier; Butterworth Scientific Ltd.
Tipo: Artigo de Revista Científica
Publicado em //2013 ENG
Relevância na Pesquisa
46.24%
Palm oil is a very important commodity. It is added to numerous products and is a biofuel. However, oil palms (OP) are subjected to fungal diseases of which Fusarium wilt and Ganoderma rots are the most important. Considerations of how climate change (CC) affects tropical economic plants are limited and for OP are even fewer. The margin for adapting to higher temperatures and changing humidity is reduced in tropical OP. Land will become increasingly unsuitable for growing OP and the plants will become stressed allowing ingress of fungal diseases. New land will be increasingly suitable where the environmental conditions are less severe than in the tropics. Novel diseases may threaten the crop. Finally, the effect of the major consequences of CC on OP fungal diseases is considered herein with a view to establishing key hypotheses.; Nelson Lima; Sariah Moen

Advances in combating fungal diseases: vaccines on the threshold

Cutler, Jim E.; Deepe, George S.; Klein, Bruce S.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
46.25%
The dramatic increase in fungal diseases in recent years can be attributed to the increased aggressiveness of medical therapy and other human activities. Immunosuppressed patients are at risk of contracting fungal diseases in healthcare settings and from natural environments. Increased prescribing of antifungals has led to the emergence of resistant fungi, resulting in treatment challenges. These concerns, together with the elucidation of the mechanisms of protective immunity against fungal diseases, have renewed interest in the development of vaccines against the mycoses. Most research has used murine models of human disease and, as we review in this article, the knowledge gained from these studies has advanced to the point where the development of vaccines targeting human fungal pathogens is now a realistic and achievable goal.

Plant Chitinases and Their Roles in Resistance to Fungal Diseases

Punja, Zamir K.; Zhang, Ye-Yan
Fonte: Society of Nematologists Publicador: Society of Nematologists
Tipo: Artigo de Revista Científica
Publicado em /12/1993 EN
Relevância na Pesquisa
46.16%
Chitinases are enzymes that hydrolyze the N-acetylglucosamine polymer chitin, and they occur in diverse plant tissues over a broad range of crop and noncrop species. The enzymes may be expressed constitutively at low levels but are dramatically enhanced by numerous abiotic agents (ethylene, salicylic acid, salt solutions, ozone, UV light) and by biotic factors (fungi, bacteria, viruses, viroids, fungal cell wall components, and oligosaccharides). Different classes of plant chitinases are distinguishable by molecular, biochemical, and physicochemical criteria. Thus, plant chitinases may differ in substrate-binding characteristics, localization within the cell, and specific activities. Because chitin is a structural component of the cell wall of many phytopathogenic fungi, extensive research has been conducted to determine whether plant chitinases have a role in defense against fungal diseases. Plant chitinases have different degrees of antifungal activity to several fungi in vitro. In vivo, although rapid accumulation and high levels of chitinases (together with numerous other pathogenesis-related proteins) occur in resistant tissues expressing a hypersensitive reaction, high levels also can occur in susceptible tissues. Expression of cloned chitinase genes in transgenic plants has provided further evidence for their role in plant defense. The level of protection observed in these plants is variable and may be influenced by the specific activity of the enzyme...

Defining Responses to Therapy and Study Outcomes in Clinical Trials of Invasive Fungal Diseases: Mycoses Study Group and European Organization for Research and Treatment of Cancer Consensus Criteria

Segal, Brahm H.; Herbrecht, Raoul; Stevens, David A.; Ostrosky-Zeichner, Luis; Sobel, Jack; Viscoli, Claudio; Walsh, Thomas J.; Maertens, Johan; Patterson, Thomas F.; Perfect, John R.; Dupont, Bertrand; Wingard, John R.; Calandra, Thierry; Kauffman, Carol
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em 01/09/2008 EN
Relevância na Pesquisa
46.13%
Invasive fungal diseases (IFDs) have become major causes of morbidity and mortality among highly immunocompromised patients. Authoritative consensus criteria to diagnose IFD have been useful in establishing eligibility criteria for antifungal trials. There is an important need for generation of consensus definitions of outcomes of IFD that will form a standard for evaluating treatment success and failure in clinical trials. Therefore, an expert international panel consisting of the Mycoses Study Group and the European Organization for Research and Treatment of Cancer was convened to propose guidelines for assessing treatment responses in clinical trials of IFDs and for defining study outcomes. Major fungal diseases that are discussed include invasive disease due to Candida species, Aspergillus species and other molds, Cryptococcus neoformans, Histoplasma capsulatum, and Coccidioides immitis. We also discuss potential pitfalls in assessing outcome, such as conflicting clinical, radiological, and/or mycological data and gaps in knowledge.

Radioimmunotherapy of Fungal Diseases: The Therapeutic Potential of Cytocidal Radiation Delivered by Antibody Targeting Fungal Cell Surface Antigens

Nosanchuk, Joshua D.; Dadachova, Ekaterina
Fonte: Frontiers Research Foundation Publicador: Frontiers Research Foundation
Tipo: Artigo de Revista Científica
Publicado em 12/01/2012 EN
Relevância na Pesquisa
46.33%
Radioimmunotherapy is the targeted delivery of cytocidal radiation to cells via specific antibody. Although mature for the treatment of cancer, RIT of infectious diseases is in pre-clinical development. However, as there is an obvious and urgent need for novel approaches to treat infectious diseases, RIT can provide us with a powerful approach to combat serious diseases, including invasive fungal infections. For example, RIT has proven more effective than standard amphotericin B for the treatment of experimental cryptococcosis. This review will discuss the concepts of RIT, its applications for infectious diseases, and the strides made to date to bring RIT of infectious diseases to fruition. Finally, we will discuss the potential of PAN-FUNGAL RIT, the targeting of conserved fungal cell surface antigens by RIT, as a treatment modality for fungi prior to the formal microbiological identification of the specific pathogen. In sum, RIT provides a mechanism for the targeted killing of drug susceptible or resistant fungi irrespective of the host immune status and may dramatically reduce the length of therapy currently required for many invasive fungal diseases.

IMMUNOGLOBULINS IN DEFENSE, PATHOGENESIS AND THERAPY OF FUNGAL DISEASES

Casadevall, Arturo; Pirofski, Liise-anne
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em 17/05/2012 EN
Relevância na Pesquisa
46.18%
Only two decades ago antibodies to fungi were thought to have little or no role in protection against fungal diseases. However, subsequent research has provided convincing evidence that certain antibodies can modify the course of fungal infection to the benefit or detriment of the host. Hybridoma technology was the breakthrough that enabled the characterization of antibodies to fungi, illuminating some of the requirements for antibody efficacy. As discussed in this review, fungal specific antibodies mediate protection through direct actions on fungal cells and through classical mechanisms such as phagocytosis and complement activation. Although mechanisms of antibody-mediated protection are often species-specific, numerous fungal antigens can be targeted to generate vaccines and therapeutic immunoglobulins. Furthermore, the study of antibody function against medically important fungi has provided fresh immunological insights into the complexity of humoral immunity that are likely to apply to other pathogens.

Challenges in prevention, diagnosis and therapy of emerging fungal diseases. Aspergillosis: A case study

Sarma, P. Usha; Sarma, P V G K; Madan, Taruna
Fonte: Springer India Publicador: Springer India
Tipo: Artigo de Revista Científica
Publicado em /08/2000 EN
Relevância na Pesquisa
56.24%
Diseases caused by pathogenic filamentous fungi, are an emerging threat to public health in the wake of increasing incidence of HIV and tuberculosis. At this point, discovery and development of fungal therapeutics and diagnostics are serious challenges for biomedical researchers. Recent technological advances in genomics and proteomics offer great scope for development of preventive and therapeutic measures for fungal diseases.Aspergillus, one of the medically important filamentous pathogenic fungi causes a wide spectrum of clinical disorders ranging from allergic aspergillosis to systemic invasive aspergillosis. Increase in incidence of drug resistance and the cytotoxic effects are two serious limitations of the antifungal drugs presently in use. This is primarily due to lack of understanding of biological mechanisms operative in these fungi. Today, it is possible to understand the biological mechanisms of the fungus for its colonisation, survival and invasion of the host. Future developments based on such leads can result in development of precise and specific diagnostic, therapeutic and preventive measures for a wide clinical spectrum of fungal diseases.

Diagnostic methods for invasive fungal diseases in patients with hematologic malignancies

Riwes, Mary Mansour; Wingard, John R
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /12/2012 EN
Relevância na Pesquisa
46.16%
Invasive fungal disease is associated with increased morbidity and mortality in hematologic malignancy patients and hematopoietic stem cell transplant recipients. Timely recognition and treatment of invasive fungal diseases in these patients are essential and decrease mortality. However, conventional definitive diagnostic methods are difficult and time consuming. While conventional microbiological and histopathological methods are still needed for a definitive diagnosis of invasive fungal disease, new noninvasive diagnostic methods including serologic and molecular biomarkers are now available. These new diagnostic methods facilitate an early diagnosis of invasive fungal disease and allow for utilization of a pre-emptive treatment approach, which may ultimately lead to improved treatment outcomes and reduced toxicity.

Detection of Infectious Fungal Diseases of Frogs Inhabiting in Korea

Kim, Suk; Eom, Ahn-Heum; Park, Daesik; Ra, Nam-Yong
Fonte: The Korean Society of Mycology Publicador: The Korean Society of Mycology
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
46.08%
In recent years, there has been a rapid decrease in amphibian populations worldwide, and infectious diseases have been associated with this decline. Diseased frogs inhabiting Korea were collected from fields, and the diseases were identified by morphological and molecular analyses. Two fungal diseases-saprolegniasis and chromomycosis-were detected in the frogs. Saprolegniasis caused by Saprolegnia spp. was found in Rana plancyi chosenica from Gangwon-do and Rana huanrenensis from Chungbuk. Chromomycosis, which is caused by infection with Cladosporium cladosporioides, was detected in Rana catesbeiana from Busan.

Recent trends and perspectives of molecular markers against fungal diseases in wheat

Goutam, Umesh; Kukreja, Sarvjeet; Yadav, Rakesh; Salaria, Neha; Thakur, Kajal; Goyal, Aakash K.
Fonte: Frontiers Media S.A. Publicador: Frontiers Media S.A.
Tipo: Artigo de Revista Científica
Publicado em 25/08/2015 EN
Relevância na Pesquisa
46.21%
Wheat accounts for 19% of the total production of major cereal crops in the world. In view of ever increasing population and demand for global food production, there is an imperative need of 40–60% increase in wheat production to meet the requirement of developing world in coming 40 years. However, both biotic and abiotic stresses are major hurdles for attaining the goal. Among the most important diseases in wheat, fungal diseases pose serious threat for widening the gap between actual and attainable yield. Fungal disease management, mainly, depends on the pathogen detection, genetic and pathological variability in population, development of resistant cultivars and deployment of effective resistant genes in different epidemiological regions. Wheat protection and breeding of resistant cultivars using conventional methods are time-consuming, intricate and slow processes. Molecular markers offer an excellent alternative in development of improved disease resistant cultivars that would lead to increase in crop yield. They are employed for tagging the important disease resistance genes and provide valuable assistance in increasing selection efficiency for valuable traits via marker assisted selection (MAS). Plant breeding strategies with known molecular markers for resistance and functional genomics enable a breeder for developing resistant cultivars of wheat against different fungal diseases.

New diseases caused by virus, fungi and also a bacterium on rubber from Brazil and their impact on international quarantine.

JUNQUEIRA, N.T.V.; GASPAROTTO, L.; MORAES, V.H.F.; SILVA, H.M.; LIM, T.M.
Fonte: In: REGIONAL CONFERENCE ON PLANT QUARANTINE SUPORT FOR AGRICULTURAL DEVELOPMENT, 1985, Kuala Lumpur. Proceedings... Kuala Lumpur: RRIM, 1985. Publicador: In: REGIONAL CONFERENCE ON PLANT QUARANTINE SUPORT FOR AGRICULTURAL DEVELOPMENT, 1985, Kuala Lumpur. Proceedings... Kuala Lumpur: RRIM, 1985.
Tipo: Artigo em anais de congresso (ALICE) Formato: p.253-260
EN
Relevância na Pesquisa
46.08%
More recently, leaf diseases attributable to virus, other fungi and possibly a bacterium were well recorded as a new disase of the rubber tree. In the state of Amazonas, symptoms of a systemic infection caused by virus (being identified), typified by leaf mosaic, little leaf, malformation and tree stunt were confirmed in clonal nurseries and field plantings in several clones at CNPSD. In tests, the symptoms of virus appeared more distinct at temperatures below 22oC. The new fungal leaf pathogens discovered in the nurseries and fields are Corynespora cassiicola, Periconia manihoticola (previously of minor importance), and an Ascomycete (Dothideaceae) in association with Phyllachora huberi yet to be identified. Also discovered were leaf symptoms in the form of tiny lesions, followed by premature leaf yellowing and fall, suggestive of a bacterial infection. These were reproduced in artificial inoculation with a culture of the bacterium repeatedly isolated from fields of clones Fx 3864, PFB 5, IAN 873 and PA 31. Relating these potentially dangerous new diseases to the welll-being of the rubber industry worldwide, international quarantine measures adopted today against Microcyclus ulei alone must now be reviewed. These should include additional measures for the inspection...

Automatic detection of patients with invasive fungal disease from free-text computed tomography (CT) scans

Martinez, David; Ananda-Rajah, Michelle R.; Suominen, Hanna; Slavin, Monica A.; Thursky, Karin A.; Cavedon, Lawrence
Fonte: Elsevier Publicador: Elsevier
Tipo: Artigo de Revista Científica
Relevância na Pesquisa
46.12%
BACKGROUND: Invasive fungal diseases (IFDs) are associated with considerable health and economic costs. Surveillance of the more diagnostically challenging invasive fungal diseases, specifically of the sino-pulmonary system, is not feasible for many hospitals because case finding is a costly and labour intensive exercise. We developed text classifiers for detecting such IFDs from free-text radiology (CT) reports, using machine-learning techniques. METHOD: We obtained free-text reports of CT scans performed over a specific hospitalisation period (2003-2011), for 264 IFD and 289 control patients from three tertiary hospitals. We analysed IFD evidence at patient, report, and sentence levels. Three infectious disease experts annotated the reports of 73 IFD-positive patients for language suggestive of IFD at sentence level, and graded the sentences as to whether they suggested or excluded the presence of IFD. Reliable agreement between annotators was obtained and this was used as training data for our classifiers. We tested a variety of Machine Learning (ML), rule based, and hybrid systems, with feature types including bags of words, bags of phrases, and bags of concepts, as well as report-level structured features. Evaluation was carried out over a robust framework with separate Development and Held-Out datasets. RESULTS: The best systems (using Support Vector Machines) achieved very high recall at report- and patient-levels over unseen data: 95% and 100% respectively. Precision at report-level over held-out data was 71%; however...

Estimating the burden of fungal disease in Vietnam

Beardsley, J; Denning, DW; Chau, NV; Yen, NTB; Crump, JA; Day, JN
Fonte: John Wiley & Sons, Ltd Publicador: John Wiley & Sons, Ltd
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
46.09%
Data regarding the prevalence of fungal infections in Vietnam are limited yet they are likely to occur more frequently as increasingly sophisticated healthcare creates more iatrogenic risk factors. In this study, we sought to estimate baseline incidence and prevalence of selected serious fungal infections for the year 2012. We made estimates with a previously described actuarial method, using reports on the incidence and prevalence of various established risk factors for fungal infections from Vietnam, or similar environments, supplemented by personal communications. Global data were used if local data were unavailable. We estimated 2 352 748 episodes of serious fungal infection occurred in Vietnam in 2012. Frequent conditions included recurrent vaginal candidiasis (3893/100 000 women annually), tinea capitis (457/100 000 annually) and chronic pulmonary aspergillosis (61/100 000/5 year period). We estimated 140 cases of cryptococcal meningitis, 206 of penicilliosis and 608 of Pneumocystis jirovecii pneumonia. This is the first summary of Vietnamese fungal infections. The majority of severe disease is due to Aspergillus species, driven by the high prevalence of pulmonary tuberculosis. The AIDS epidemic highlights opportunistic infections...

Recent Fungal Diseases of Crop Plants: Is Lateral Gene Transfer a Common Theme?

Oliver, Richard Peter; Solomon, Peter
Fonte: APS Press Publicador: APS Press
Tipo: Artigo de Revista Científica
Relevância na Pesquisa
46.25%
A cursory glance at old textbooks of plant pathology reveals that the diseases which are the current scourge of agriculture in many parts of the world are a different set from those that were prominent 50 or 100 years ago. Why have these new diseases aris

Optimizing Outcomes in Immunocompromised Hosts: Understanding the Role of Immunotherapy in Invasive Fungal Diseases

Ravikumar, Sharada; Win, Mar Soe; Chai, Louis Yi Ann
Fonte: Frontiers Media S.A. Publicador: Frontiers Media S.A.
Tipo: Artigo de Revista Científica
Publicado em 26/11/2015 EN
Relevância na Pesquisa
46.16%
A major global concern is the emergence and spread of systemic life-threatening fungal infections in critically ill patients. The increase in invasive fungal infections, caused most commonly by Candida and Aspergillus species, occurs in patients with impaired defenses due to a number of reasons such as underlying disease, the use of chemotherapeutic and immunosuppressive agents, broad-spectrum antibiotics, prosthetic devices and grafts, burns, neutropenia and HIV infection. The high morbidity and mortality associated with these infections is compounded by the limited therapeutic options and the emergence of drug resistant fungi. Hence, creative approaches to bridge the significant gap in antifungal drug development needs to be explored. Here, we review the potential anti-fungal targets for patient-centered therapies and immune-enhancing strategies for the prevention and treatment of invasive fungal diseases.

GERBERA DISEASES IN THE STATE OF PARANÁ, BRAZIL; DOENÇAS EM CULTIVOS DE GÉRBERA NO ESTADO DO PARANÁ

FERRONATO, Marlene de Lurdes; UTFPR; LIMA NETO, Vismar da Costa; UFPR; TOMAZ, Roberto; SEAB
Fonte: UFPR Publicador: UFPR
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; Artigo Avaliado pelos Pares Formato: application/pdf
Publicado em 22/10/2008 ENG
Relevância na Pesquisa
46.1%
In surveys carried out in nine regions of Paraná State between the 1st semester of 2004 and the 2nd semester of 2006, comprising 15 properties growing cut and potted gerbera (Gerbera jamesonii), nine plant pathogenic agents were identified: eight of fungal and one of bacterial nature (Erysiphe cichoracearum, Pythium sp., Phytophthora sp., Fusarium oxysporum, Cercospora gerberae, Botrytis cinerea, Albugo tragopogonis, Capnodium sp. and Pseudomonas cichorii). The identification of these pathogens, descriptions of symptoms and period of occurrence provides some basic information for future researches on epidemiology and control of gerbera diseases in the Paraná State, Brazil.; Em inspeções realizadas em 15 propriedades produtoras de gérbera (Gerbera jamesonii H. Bolus ex Hook. f.) de corte e de vaso, no período compreendido entre o 1º semestre de 2004 e 2º semestre de 2006, abrangendo nove regiões do Estado do Paraná, foram identificados nove agentes causais de doenças: oito de natureza fúngica e uma bacteriana: Erysiphe cichoracearum, Pythium sp., Phytophthora sp., Fusarium oxysporum, Cercospora gerberae, Botrytis cinerea, Albugo tragopogonis, Capnodium sp. e Pseudomonas cichorii.  A identificação dos agentes causais das doenças...