Página 1 dos resultados de 6408 itens digitais encontrados em 0.033 segundos

A brief review of chronic exercise intervention to prevent autonomic nervous system changes during the aging process

WICHI, Rogério Brandão; DE ANGELIS, Kátia; JONES, Lia; IRIGOYEN, Maria Claudia
Fonte: Faculdade de Medicina / USP Publicador: Faculdade de Medicina / USP
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
55.99%
The aging process is associated with alterations in the cardiovascular and autonomic nervous systems. Autonomic changes related to aging involve parasympathetic and sympathetic alterations leading to a higher incidence of cardiovascular disease morbidity and mortality. Several studies have suggested that physical exercise is effective in preventing deleterious changes. Chronic exercise in geriatrics seems to be associated with improvement in the cardiovascular system and seems to promote a healthy lifestyle. In this review, we address the major effects of aging on the autonomic nervous system in the context of cardiovascular control. We examine the use of chronic exercise to prevent cardiovascular changes during the aging process.

Cardiovascular effects of acetylcholine microinjection into the ventrolateral and dorsal periaqueductal gray of rats

DEOLINDO, Milena Vieira; PELOSI, Gislaine Garcia; BUSNARDO, Cristiane; RESSTEL, Leonardo Barbosa Moraes; CORREA, Fernando Morgan Aguiar
Fonte: ELSEVIER SCIENCE BV Publicador: ELSEVIER SCIENCE BV
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
55.95%
In the present study, we describe the cardiovascular effects of local acetylcholine (Ach) microinjection into both the ventrolateral (vlPAG) and dorsal (dPAG) periaqueductal gray areas of anesthetized rats and the possible local receptors involved with these responses. Microinjection of Ach (9, 27, 45 or 81 nmol/50 nL) into the vlPAG caused dose-related depressor responses. These hypotensive responses were blocked by local pretreatment with increasing doses of the nonselective muscarinic antagonist atropine (1, 3 or 9 nmol/50 nL). The microinjection of Ach into the dPAG caused no significant cardiovascular responses in anesthetized rats. In conclusion, the present findings suggest that a cholinergic system present in the vlPAG, but not in the dPAG, is involved with cardiovascular system control. Moreover, these cardiovascular responses evoked by Ach are mediated by muscarinic receptors. (C) 2010 Elsevier B.V. All rights reserved.

"Efeitos do tabagismo sobre o sistema cardiovascular: hemodinâmica e propriedades elásticas arteriais" ; Effects of cigarette smoking on cardiovascular system: hemodynamic and elastic properties arterial

Silva, Maria Alice Melo Rosa Tavares
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 25/07/2005 PT
Relevância na Pesquisa
65.95%
Objetivo Avaliar os efeitos do tabagismo sobre o sistema cardiovascular, através de metodologia não invasiva, analisando as alterações hemodinâmicas clínicas e propriedades elásticas arteriais, após exposição ao fumo. Métodos Estudo realizado em 45 voluntários sendo 18 (F) e 27 (M), fumantes T (n = 25, idade 40 ± 9 anos) e não fumantes NT (n = 20, idade 39 ± 9 anos), que foram submetidos a determinação do monóxido de carbono (CO) e avaliação das propriedades elásticas arteriais por ultrassonografia e teste de função endotelial (hiperemia reativa - HR) antes (B1) e após (B2) a exposição por 20 minutos a um cigarro ou à degustação de uma bala. Resultados Os grupos NT e T mostraram-se homogêneos. A concentração de CO no grupo T era maior do que no grupo NT em condições basais. A concentração de CO no grupo NT não variou antes e após à exposição proposta (bala) mas no grupo T aumentou de maneira significante após o cigarro. A pressão arterial sistólica (PAS) foi igual no B1 nos dois grupos, mas significativamente maior no B2 para o Gr T. A pressão arterial diastólica (PAD) no B1 e B2 não mostrou variação estatísticamente significante nos dois grupos. A freqüência cardíaca (FC) apresentou comportamento estatisticamente diferente nos dois grupos (NT apresentou redução e T apresentou aumento). Em relação às propriedades elásticas arteriais e resposta do fluxo regional: a complacência e a distensibilidade já se mostraram diferentes (p < 0...

Desenvolvimento de um simulador da mecânica cardiovascular humana controlada pelo mecanismo reflexo baroceptor.; Development of a simulator of the human cardiovascular mechanics controlled by baroceptor reflex mechanism.

Lonardoni, José Augusto Calvo
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 14/09/2006 PT
Relevância na Pesquisa
55.94%
Nos últimos anos, o ensino de fisiologia tem sido fortemente beneficiado pelo desenvolvimento de modelos matemáticos e simuladores de paciente capazes de reproduzir com segurança partes específicas ou sistemas fisiológicos completos. Estudos mostram que aulas teóricas aliadas a simulações conseguem potencializar o nível de compreensão dos conceitos envolvidos. O principal objetivo deste trabalho consiste no desenvolvimento de um simulador do sistema cardiovascular, capaz de representar de forma didática a dinâmica do ciclo cardíaco. A disponibilidade de simuladores deste tipo é reduzida, e limitada a modelos simplificados ou interfaces pouco amigáveis. De modo a conseguir maior flexibilidade nas situações simuladas e um adequado grau de proximidade com o sistema real, decidiu-se pela utilização de um modelo matemático da fisiologia cardiovascular para o cálculo das variáveis e parâmetros atuantes no plano de fundo do simulador. O desenvolvimento deste modelo constitui o segundo objetivo deste trabalho. Devido ao grau de complexidade desejado, optou-se pela utilização de um modelo existente na literatura, acrescido dos parâmetros que fossem considerados ausentes. O resultado foi um modelo com oito compartimentos vasculares e quatro compartimentos representando as câmaras do coração...

Organogênese do aparelho respiratório e sistema cardiovascular de embriões bovinos provenientes de transferência nuclear e fertilização in vitro; Organogenesis of the respiratory and cardiovascular system of bovine embryos from nuclear transfer and IVF

Alberto, Míryan Lança Vilia
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 13/12/2010 PT
Relevância na Pesquisa
55.92%
Alterações morfogênicas do aparelho cardiorespiratório de bovinos provenientes de fecundação in vitro e transferência nuclear são um dos principais fatores responsáveis pela alta incidência de mortalidade embrionária, fetal e pós-natal. Utilizamos técnicas empregadas em microscopia de luz para estudar o desenvolvimento do coração e pulmão nestes animais. Verificamos que em embriões provenientes de fecundação in vitro, aos 28 dias de gestação, aparece o tubo laringotraqueal e sua septação através da prega traqueoesofágica. Neste mesmo período os embriões apresentaram cavidade pericárdica, átrio dividido em direito e esquerdo, cone cardíaco, seio venoso, camada de miocárdio e epicárdio. O brônquio traqueal foi observado em embriões com idade gestacional de 36 dias a partir de um brotamento na porção lateral direita da traquéia, cranial a sua bifurcação. Aos 44 dias de gestação os brotos pulmonares dos embriões apresentaram brônquios principais originando brotamentos de brônquios segmentares. O mesênquima de sustentação em diferenciação continha vasos sangüíneos dispersos, diferentemente de embriões provenientes de TN, que com 68 dias de gestação apresentou pulmão em fase pseudoglandular contendo brotos de bronquíolos e poucos vasos sangüíneos nos cortes obtidos e analisados. Com 70 dias...

Efeito do hipertiroidismo experimental, induzido em ratas durante a gestação, sobre componentes do sistema renina-angiotensina cardíaco da prole.; Effect of experimental hyperthyroidism induced in female rats during pregnancy in the components of cardiac Renin-Angiotensin System of the offspring.

Shibata, Caroline Emy Rodrigues
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 25/02/2011 PT
Relevância na Pesquisa
56.06%
Durante a gestação normal, o Sistema Renina-Angiotensina (SRA) exerce um papel de importância vital no balanço de sais, pressão sanguínea e homeostase da água e, consequentemente, no bem estar da mãe e do feto. Neste sentido, merece destaque não apenas o SRA clássico (descrito inicialmente como um sistema puramente endócrino), mas também, o SRA local, no caso, útero-placentário, onde nos tecidos materno e fetal os vários componentes do sistema se comportam diferentemente, sob regulação e estímulos locais. As perturbações do SRA útero¬placentário podem ocasionar hemorragias e redução no fluxo sanguíneo entre mãe e feto, podendo levar, como conseqüência, à pré-eclampsia e crescimento intrauterino retardado. Já é bem estabelecido que disfunções da tireóide, como ocorre no hipertiroidismo, promovem amplas alterações no sistema cardiovascular, agindo sobre contratilidade cardíaca, débito cardíaco, pressão sanguínea e resistência vascular sistêmica. Sabe-se ainda que o hipertiroidismo é responsável por importantes alterações sobre o padrão de comportamento dos vários componentes do SRA no indivíduo adulto, e estas, por sua vez, também estão envolvidas com o aparecimento de alterações cardiovasculares. Assim...

Could a high-fat diet rich in unsaturated fatty acids impair the cardiovascular system?

Medei, Emiliano; Lima-Leopoldo, Ana Paula; Pereira-Junior, Pedro Paulo; Leopoldo, Andre Soares; Salome Campos, Dijon Henrique; Raimundo, Juliana Montani; Sudo, Roberto Takashi; Zapata-Sudo, Gisele; Bruder-Nascimento, Thiago; Cordellini, Sandra; Matheus Na
Fonte: Elsevier B.V. Publicador: Elsevier B.V.
Tipo: Artigo de Revista Científica Formato: 542-548
ENG
Relevância na Pesquisa
55.93%
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Processo FAPESP: 07/53267-3; Processo FAPESP: 09/03771-2; BACKGROUND: Dyslipidemia results from consumption of a diet rich in saturated fatty acids and is usually associated with cardiovascular disease. A diet rich in unsaturated fatty acids is usually associated with improved cardiovascular condition.OBJECTIVE: To investigate whether a high-fat diet rich in unsaturated fatty acids (U-HFD)-in which fatty acid represents approximately 45% of the total calories-impairs the cardiovascular system.METHODS: Male, 30-day-old Wistar rats were fed a standard (control) diet or a U-HFD containing 83% unsaturated fatty acid for 19 weeks. The in vivo electrocardiogram, the spectral analysis of heart rate variability, and the vascular reactivity responses to phenylephrine, acetylcholine, noradrenaline and prazosin in aortic ring preparations were analyzed to assess the cardiovascular parameters.RESULTS: After 19 weeks, the U-HFD rats had increased total body fat, baseline glucose levels and feed efficiency compared with control rats. However, the final body weight, systolic blood pressure, area under the curve for glucose, calorie intake and heart weight/final body weight ratio were similar between the groups. In addition...

Importância da região anteroventral do terceiro ventrículo (AV3V) no controle cardiovascular e do equilíbrio hidroeletrolítico

Vieira, Alexandre A.; De Paula, Patricia M.; De Luca Jr., Laurival A.; Colombari, Débora S. A.; Colombari, Eduardo; Menani, Jose Vanderlei
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Conferência ou Objeto de Conferência Formato: 21-27
POR
Relevância na Pesquisa
55.95%
The maintenance of the arterial pressure in normal levels is important for the homeostasis of body fluids. The central nervous system regulating sympathetic and parasympathetic autonomic efferent can adjust arterial pressure which allows animals or human to face different daily activities with the best performance. Different central areas are responsible for the control of autonomic discharges to cardiovascular system and many of them are also involved in the control of fluid electrolyte balance. One of these areas is the tissue surrounding the anteroventral third ventricle (AV3V region) localized in the forebrain and a main central site for angiotensin II receptors and osmoreceptors. The AV3V lesions impair the development of many models of experimental hypertension in rats and the pressor responses to different stimuli. Lesions of the AV3V region also reduce dipsogenic responses to angiotensin II, central cholinergic activation, water deprivation and increase in plasma osmolarity, atrial natriuretic peptide secretion produced by body fluid expansion and the increase in renal excretion to central cholinergic activation. Recent evidence also suggests the participation of AV3V region in pressor responses produced by the activation of medullary mechanisms.

Spirituality/religiosity and cardiovascular system

Valente, Vitor Engrácia; Quitério, Robison José; Vanderlei, Luiz Carlos
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Artigo de Revista Científica Formato: 1-5
POR
Relevância na Pesquisa
66.04%
Introduction: Spirituality/religiosity is associated to well-being. In this article, we describe the association between spirituality/religiosity and cardiovascular system. Materials and methods: We performed searches using Medline, SciELO, Lilacs and Cochrane databases using crossing between the keywords “spirituality,” “cardiovascular system,” “parasympathetic nervous system,” and “sympathetic nervous system.”Results: The electronic search yielded 65 references by crossing the terms “spirituality” and “cardiovascular system.” Among these, the first round of elimination resulted in exclusion of 55 titles and abstracts that were not clearly related to the subject of the review. The titles of the remaining 10 abstracts were submitted to a final evaluation that accounted for the inclusion criteria. An investigation into the reference lists confirmed the absence of relevant documents. Summaries of the analysed studies were selected. Discussion: Among 10 studies selected, 8 of them indicated that spirituality/religiosity is very important for the cardiovascular system, whereas only 2 found no significant association between the two variables in women. Conclusion: We suggest that spirituality/religiosity is an alternative and non-pharmacological therapy for cardiovascular disorders.

Development of Anatomophysiologic Knowledge Regarding the Cardiovascular System: From Egyptians to Harvey

Bestetti,Reinaldo Bulgarelli; Restini,Carolina Baraldi A.; Couto,Lucélio B.
Fonte: Sociedade Brasileira de Cardiologia - SBC Publicador: Sociedade Brasileira de Cardiologia - SBC
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2014 EN
Relevância na Pesquisa
65.86%
Our knowledge regarding the anatomophysiology of the cardiovascular system (CVS) has progressed since the fourth millennium BC. In Egypt (3500 BC), it was believed that a set of channels are interconnected to the heart, transporting air, urine, air, blood, and the soul. One thousand years later, the heart was established as the center of the CVS by the Hippocratic Corpus in the medical school of Kos, and some of the CVS anatomical characteristics were defined. The CVS was known to transport blood via the right ventricle through veins and the pneuma via the left ventricle through arteries. Two hundred years later, in Alexandria, following the development of human anatomical dissection, Herophilus discovered that arteries were 6 times thicker than veins, and Erasistratus described the semilunar valves, emphasizing that arteries were filled with blood when ventricles were empty. Further, 200 years later, Galen demonstrated that arteries contained blood and not air. With the decline of the Roman Empire, Greco-Roman medical knowledge about the CVS was preserved in Persia, and later in Islam where, Ibn Nafis inaccurately described pulmonary circulation. The resurgence of dissection of the human body in Europe in the 14th century was associated with the revival of the knowledge pertaining to the CVS. The main findings were the description of pulmonary circulation by Servetus...

Cardiovascular effects of monoterpenes: a review

Santos,Márcio R. V.; Moreira,Flávia V.; Fraga,Byanka P.; Souza,Damião P. de; Bonjardim,Leonardo R.; Quintans-Junior,Lucindo J.
Fonte: Sociedade Brasileira de Farmacognosia Publicador: Sociedade Brasileira de Farmacognosia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/08/2011 EN
Relevância na Pesquisa
55.95%
The monoterpenes are secondary metabolites of plants. They have various pharmacological properties including antifungal, antibacterial, antioxidant, anticancer, anti-spasmodic, hypotensive, and vasorelaxant. The purpose of this research was to review the cardiovascular effects of monoterpenes. The data in this resarch were collected using the Internet portals Pubmed, Scopus, and ISI Web of Knowledge between the years 1987 and 2010. In the study 33 monoterpenes were included, which were related to each of the thirteen individual words: artery, cardiovascular, heart, myocyte, vasorelaxant, vessel, hypotension, hypotensive, cardiomyocyte, ventricular, vasodilatory, aorta, and aortic. The research utilized 22 articles published mainly in the journals Phytomedicine, Fundamental Clinical Pharmacology, Planta Medica, Life Science, European Journal of Pharmacology, and Brazilian Journal of Medical and Biological Research. Of the 33 monoterpenes studied surveyed, sixteen of them had already been studied for their effects on the cardiovascular system: carvacrol, citronellol, p-cymene, eucalyptol (1,8-cineole), linalool, menthol, myrtenal, myrtenol, α-pinene, rotundifolone (piperitenone oxide), sobrerol, thymol, α-limonene, α-terpinen-4-ol...

Effect of Global Postural Reeducation on cardiovascular system of healthy subjects

Abreu,Elizângela Márcia de Carvalho; Cunha,Tatiana Sousa; Paula Júnior,Alderico Rodrigues de; Oliveira,Marco Antonio de
Fonte: Pontifícia Universidade Católica do Paraná Publicador: Pontifícia Universidade Católica do Paraná
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/09/2014 EN
Relevância na Pesquisa
65.88%
Objective To evaluate the effect of Global Postural Reeducation (GPR) on cardiovascular system by heart rate variability (HRV), blood pressure (BP) and heart rate (HR). Materials and methods Seventeen healthy men (22.47 ± 3.02 years) were submitted to the postures frog on the floor, frog on the air, sitting, standing against the wall and inclined standing, two postures per session. The systolic and diastolic blood pressure (SBP and DBP) and HR were recorded. The intervals between heartbeats were collected during the whole session (Polar S810i). The frequency domain was analyzed (Wavelet Transform), the low frequency (LF) and high frequency (HF) were obtained. The data were analyzed by ANOVA and Tukey (p < 0.05). Results Increased LF/HF ratio was observed in the frog on the floor (1 ± 0.1 vs. 2 ± 0.3 p < 0.05) and on the air postures (1 ± 0.1 vs. 2 ± 0.2 p < 0.01). There was an increase in SBP in the postures frog on the floor (123 ± 2 vs. 136 ± 4 p < 0.05), frog on the air (122 ± 2 vs. 133 ± 3 p < 0.05), standing against the wall (123 ± 2 vs. 136 ± 4 p < 0.05), inclined standing (124 ± 3 vs. 146 ± 5 p < 0.05). There was increase of DBP in the postures frog on the floor (69 ± 2 vs. 81 ± 2 p < 0.01)...

A brief review of chronic exercise intervention to prevent autonomic nervous system changes during the aging process

Wichi,Rogério Brandão; De Angelis,Kátia; Jones,Lia; Irigoyen,Maria Claudia
Fonte: Faculdade de Medicina / USP Publicador: Faculdade de Medicina / USP
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/03/2009 EN
Relevância na Pesquisa
55.99%
The aging process is associated with alterations in the cardiovascular and autonomic nervous systems. Autonomic changes related to aging involve parasympathetic and sympathetic alterations leading to a higher incidence of cardiovascular disease morbidity and mortality. Several studies have suggested that physical exercise is effective in preventing deleterious changes. Chronic exercise in geriatrics seems to be associated with improvement in the cardiovascular system and seems to promote a healthy lifestyle. In this review, we address the major effects of aging on the autonomic nervous system in the context of cardiovascular control. We examine the use of chronic exercise to prevent cardiovascular changes during the aging process.

Estudo do efeito de nanopartículas magnéticas biocompatíveis no sistema cardiovascular de ratos e investigação do processo de captura e exocitose das nanoestruturas por cardiomiócitos; Study of the effect of magnetic nanoparticles biocampatible in the rat cardiovascular system and investigation of capture process and exocytosis for cardiomyocytes of nanostructures

RAMALHO, Laylla Silva
Fonte: Universidade Federal de Goiás; BR; UFG; Mestrado em Física; Ciências Exatas e da Terra Publicador: Universidade Federal de Goiás; BR; UFG; Mestrado em Física; Ciências Exatas e da Terra
Tipo: Dissertação Formato: application/pdf
POR
Relevância na Pesquisa
55.91%
Magnetic fluids consist of surface-coated magnetic nanoparticles dispersed in a liquid carrier. These nanostructures have attracted a lot of attention of the biomedical community because of its possible applications as drug carriers, disease detection, and also on the treatment of several diseases, including cardiovascular ones. This work had the following objectives: (i) evaluate the effect ex-vivo of biocompatible magnetic nanoparticles in the rat heart function and, in-vivo, in the arterial blood pressure and heart rate of the rats, as well as, (ii) investigate the endocytosis and exocytosis of the nanoparticles through a magnetophoresis technique. The samples were characterized by X-ray diffraction (XRD), Dynamic light sacttering (DLS) and Vibrating sample magnetometer (VSM). The cardiac function was evaluated by the Langendorf technique under constant flow. On the other hand, in order to evaluate the effect of nanoparticles in the cardiovascular parameters, femoral artery and vein were cannulated and arterial pressure and heart rate were measure after 24 hs. The magnetic fluid infusion in the isolated heart showed a tiny increase of the intraventricular diastólic pressure and a decrease of the intraventricular systolic pressure. No changes were observed in perfusion pressure. The infusion of the magnetic nanoparticles in the rats had not promoted any significant variations of the artery pressure or the heart rate. These results suggest that magnetic nanoparticles can be used on clinical trials. In addition...

The cardiovascular hemodynamic responses to various levels of orthostatic stress in children

Livingstone, Kristina.
Fonte: Brock University Publicador: Brock University
Tipo: Electronic Thesis or Dissertation
ENG
Relevância na Pesquisa
55.99%
The ability of the cardiovascular system to quickly and efficiently adapt to an orthostatic stress is vital for the human body to function on earth. The way in which the various aspects of the cardiovascular system work together to counteract an orthostatic stress has been previously quantified in the adult population. However, there are still many unknowns surrounding the topic of how the cardiovascular system functions to cope with this same stress in children. The purpose of this study was to describe the cardiovascular hemodynamic adaptations to various levels of orthostatic stress induced using a lower body negative pressure (LBNP) chamber in pre-pubertal boys. A secondary purpose was to determine indices of baroreceptor sensitivity (BRS) at both rest and during low levels of LBNP in this same pediatric sample. Finally, this study aimed to compare the relative responses to LBNP between the children and adults. To complete the study 20 healthy pre-pubertal boys and adult males (9.3 ± 1.1 and 23 ± 1.8 years of age respectively) were recruited and randomly exposed to three levels of LBNP (15, 20 and 25 mmHg). At rest and during the application of the LBNP heart rate (HR), manual and bcat-by-beat systolic (SBP), diastolic (DBP) and mean arterial blood pressure (MAP) were monitored continuously. Aortic diameter was measured at rest and peak aortic blood velocity (PV) was recorded continuously for at least I minute during each baseline and LBNP condition. From the raw data HR...

Maternal exposure to cadmium during gestation perturbs the vascular system of the adult rat offspring

Sáez, Daniel; Zepeda Iriarte, Ramiro Javier; Urrutia, Manuel; Hirsch, Sandra; Montenegro, Marcela; Castillo, Paula; Llanos, Miguel N.; Ronco, Ana María
Fonte: Elsevier Publicador: Elsevier
Tipo: Artículo de revista
EN
Relevância na Pesquisa
55.93%
Artículo de publicación ISI; Several cardiovascular diseases (CVD) observed in adulthood have been associated with environmental influences during fetal growth. Here, we show that maternal exposure to cadmium, a ubiquitously distributed heavy metal and main component of cigarette smoke is able to induce cardiovascular morpho-functional changes in the offspring at adult age. Heart morphology and vascular reactivity were evaluated in the adult offspring of rats exposed to 30 ppm of cadmium during pregnancy. Echocardiographic examination shows altered heart morphology characterized by a concentric left ventricular hypertrophy. Also, we observed a reduced endothelium-dependent reactivity in isolated aortic rings of adult offspring, while endotheliumindependent reactivity remained unaltered. These effects were associated with an increase of hem-oxygenase 1 (HO-1) expression in the aortas of adult offspring. The expression of HO-1 was higher in females than males, a finding likely related to the sex-dependent expression of the vascular cell adhesion molecule 1 (VCAM-1), which was lower in the adult female. All these long-term consequences were observed along with normal birth weights and absence of detectable levels of cadmium in fetal and adult tissues of the offspring. In placental tissues however...

Relação entre o sistema renina angiotensina e as respostas cardiovasculares promovidas pelo exercício físico; Relationship between the renin-angiotensin system and cardiovascular responses promoted by exercise training

Goessler, Karla F.; Polito, Marcos D.
Fonte: Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto Publicador: Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; Formato: application/pdf
Publicado em 30/09/2013 POR
Relevância na Pesquisa
56.04%
Introdução e objetivos: O sistema renina angiotensina (SRA) apresenta importante função na homeostase do sistema cardiovascular, e a ativação da via clássica resulta na formação de angiotensina II, que leva ao aumento da pressão arterial (PA). No entanto, novos estudos tem evidenciado a ativação da via da angiotensina (1-7), a qual apresenta respostas contrárias a Angiotensina II e consequentemente reduz a PA. Considerando que o exercício físico interfere nas repostas cardiovasculares, este estudo teve o propósito de revisar a literatura quanto a possível relação do treinamento físico com o SRA.Métodos: o trabalho foi dividido em sessões de estudos que envolveram animais e estudos com seres humanos. A busca destes estudos foi realizada na base Medline e os principais critérios foram amostras com animais ou seres humanos e artigos publicados em inglês. Depois de aplicados os critérios de inclusão e exclusão, foram encontrados 12 artigos envolvendo animais e oito envolvendo seres humanos.Resultados: Os estudos demonstraram que existe uma relação entre o treinamento físico e o SRA, sendo que as respostas cardiovasculares observadas após o exercício físico pode apresentar alguma relação com o SRA. Além disso...

SEMIOLOGIA CARDIOVASCULAR: INSPEÇÃO, PALPAÇÃO E PERCUSSÃO; CARDIOVASCULAR EXAMINATION: INSPECTION, PALPATION AND PERCUSSION

Pazin-Filho, Antônio; Schmidt, André; Maciel, Benedito Carlos
Fonte: Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto Publicador: Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; Formato: application/pdf
Publicado em 30/12/2004 POR
Relevância na Pesquisa
55.91%
A importância da avaliação da inspeção e da palpação do sistema cardiovascular é ressaltada. Procurou-se demonstrar a importância da interpretação dos dados obtidos na análise do ictus cordis, da perfusão periférica e dos pulsos arteriais e venosos para as diversas cardiopatias, sempre com o objetivo de sistematização.; The inspection and palpation of the physical examination of the cardiovascular system is emphatizated. The value of the analysis of the periferic perfusion and arterial and venous pulses for the systematic evaluation of the several cardiopathies is reinforced.  

A brief review of chronic exercise intervention to prevent autonomic nervous system changes during the aging process

Wichi, Rogério Brandão; De Angelis, Kátia; Jones, Lia; Irigoyen, Maria Claudia
Fonte: Universidade de São Paulo. Faculdade de Medicina Publicador: Universidade de São Paulo. Faculdade de Medicina
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; ; Formato: application/pdf
Publicado em 01/03/2009 ENG
Relevância na Pesquisa
55.99%
The aging process is associated with alterations in the cardiovascular and autonomic nervous systems. Autonomic changes related to aging involve parasympathetic and sympathetic alterations leading to a higher incidence of cardiovascular disease morbidity and mortality. Several studies have suggested that physical exercise is effective in preventing deleterious changes. Chronic exercise in geriatrics seems to be associated with improvement in the cardiovascular system and seems to promote a healthy lifestyle. In this review, we address the major effects of aging on the autonomic nervous system in the context of cardiovascular control. We examine the use of chronic exercise to prevent cardiovascular changes during the aging process.

Hypoplastic left heart syndrome: Component models for cardiovascular systems after the Norwood procedure

Abernethy, Shawn
Fonte: University of Delaware Publicador: University of Delaware
Tipo: Tese de Doutorado
Relevância na Pesquisa
55.95%
Driscoll, Tobin A.; The goal of the Norwood procedure is to provide systemic circulation in a cardiovascular system with a single ventricle. This procedure is universally performed on the patient population of newborns with a underdeveloped left ventricle, Hypoplastic Left Heart Syndrome (HLHS). Two alternative surgical methods are employed to provide the pulmonary circulation, Right Ventricle-Pulmonary Artery Conduit method and the Blalock-Taussig Shunt method. The objective of this study is to take a previous compartment model of the two cardiovascular systems, verify the physiology and accuracy of the system of ordinary differential equations, implement a simulator based on the mathematical model, and evaluate the model's capacity to produce a realistic right ventricular pressure-volume loop. A MATLAB based software tool was written to model both procedures and provide a graphical user interface for others in clinical practice. An optimizer was used to adjust the parameters in order to produce a pressure-volume loop comparable to expectations. Once a reasonable P-V loop was obtained for each model, the physiological realism of the model was analyzed to discover its validity and limitations.; University of Delaware, Department of Applied Mathematics; M.S.