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Estudo da inflexão da Serra do Garrote e sua influência na zona de falha de Vazante (MG)

Matumoto, Carolina
Fonte: Universidade Estadual Paulista (UNESP) Publicador: Universidade Estadual Paulista (UNESP)
Tipo: Trabalho de Conclusão de Curso Formato: 42 f.
POR
Relevância na Pesquisa
16.09%
The Vazante Fault Zone (VFZ), located northwestward of Minas Gerais, host the largest zinc deposit known in the Brazilian territory. This structure is hosted in Vazante’s Group rocks, a metassedimentary sequence of marine environment. Near Vazante is situated the south end of the VFZ. To the west, occur the Serra do Garrote inflexion, characterized by a curvature in the contact of Formations Serra do Garrote and Serra do Poço Verde. This structure is through the analysis of aerial imagery of the region and represented in the published geological maps. The objective of this work is to understand what causes this inflexion and determine whether it affects the VZF, causing a shift in the same, and possibly, in the mineralization as well. To this end, it was done a mapping work in the region covering the Serra do Garrote inflexion and the south end of the VFZ, in 1:25.000 scale, supplemented by petrographic description of thin section and geologic sections, with cooperated to the understanding of the structural evolution of the region. Data analysis allowed the identification of six deformation phases. The D1 an D2 phases generated the main foliation. The D3 phase generate kink bands folds, with NS axis and vertical axial plane. The fourth phase is responsible for generating the Vazante Fault Zone. The fifth phase produces low angle folds and shear zones...

Contribution of the GJB2 gene to nonsyndromic sensorineural hearing loss in the portuguese population

Matos, Tiago Daniel Lopes Morim Pereira de, 1979-
Fonte: Universidade de Lisboa Publicador: Universidade de Lisboa
Tipo: Tese de Doutorado
Publicado em //2012 ENG
Relevância na Pesquisa
16.72%
Tese de doutoramento, Biologia (Genética), Universidade de Lisboa, Faculdade de Ciências, 2012; Mutations in the GJB2 gene are responsible for a considerable proportion of nonsyndromic sensorineural hearing loss (NSSHL), in several populations. This gene is a member of a gene family coding for connexins, the subunits of the hemichannels (connexons) which form the intercellular channels of the gap junctions existing in the vertebrates and tunicates. Connexin-26 (Cx26), encoded by the GJB2 gene, is expressed in several tissues, including specific epithelial and conjunctive tissues of the cochlea, the auditory organ which is localised to the inner ear. In the cochlea, Cx26 is co-expressed with connexin-30 (Cx30), encoded by the GJB6 gene, in several cell types. Two large GJB6 deletions are involved in several hearing loss (HL) cases, as well, being most of these cases due to compound heterozygosity with a GJB2 mutation. Given the relevance of both GJB2 and GJB6 genes to the HL etiology in several populations, the molecular diagnosis of NSSHL cases with probable genetic cause is usually initiated by the analysis of the GJB2 coding region (in which most pathogenic mutations have been found), followed by the investigation of the presence of the GJB6 deletions in the cases where none or only one GJB2 mutation is found. In some cases...

A beta subunit mutation disrupting the catalytic function of Escherichia coli RNA polymerase.

Lee, J; Kashlev, M; Borukhov, S; Goldfarb, A
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em 15/07/1991 EN
Relevância na Pesquisa
15.97%
The substitution of the evolutionarily conserved Glu-813 for lysine in the beta subunit of RNA polymerase (RNAP) causes a partial loss of function in the assembled RNAP. In the presence of the four ribonucleoside triphosphates, the mutant RNAP displayed a decreased frequency of promoter clearance and diminished elongation rate. Both defects could be compensated by raising the ribonucleoside triphosphate concentration. In the abortive initiation reaction limited by the incomplete set of ribonucleoside triphosphates, the mutant RNAP generated aberrant patterns of products indicative of their enhanced loss from the RNAP-promoter complex. A model is proposed, attributing the multiple effect of the mutation to the malfunctioning of the RNAP active center.

Amino acid substitution (Ile194----Thr) in exon 5 of the lipoprotein lipase gene causes lipoprotein lipase deficiency in three unrelated probands. Support for a multicentric origin.

Henderson, H E; Ma, Y; Hassan, M F; Monsalve, M V; Marais, A D; Winkler, F; Gubernator, K; Peterson, J; Brunzell, J D; Hayden, M R
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /06/1991 EN
Relevância na Pesquisa
25.97%
Studies on the molecular biology of lipoprotein lipase (LPL) deficiency have been facilitated by the availability of LPL gene probes and the recent characterization of gene mutations underlying human LPL deficiency. Typically, missense mutations have predominated and show a preferential localization to exons 4 and 5. This distribution supports earlier studies attributing functional significance to residues encoded by these exons. We now report a further missense mutation within exon 5 of the LPL gene in three unrelated patients. Amplification of individual exons by the polymerase chain reaction and direct sequencing revealed a T----C transition at codon 194 of the LPL cDNA which results in a substitution of threonine for isoleucine at this residue. The catalytic abnormality induced by this mutation was confirmed through in vitro mutagenesis studies in COS-1 cells. Transfection with a LPL cDNA containing the codon 194 transition resulted in the synthesis and secretion of a catalytically defective protein. The Thr194 substitution was associated with two different DNA haplotypes, consistent with a multicentric origin for this mutation.

An outbreak of illness among schoolchildren in London: toxic poisoning not mass hysteria.

Aldous, J C; Ellam, G A; Murray, V; Pike, G
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /02/1994 EN
Relevância na Pesquisa
15.97%
STUDY OBJECTIVE--To determine the cause of an outbreak of acute gastrointestinal illness that occurred shortly after lunch in children attending a school in London, UK. DESIGN--A questionnaire survey of children at the affected school was carried out on the day after the incident. Microbiological, environmental, and toxicological investigations were also undertaken. SETTING--A school in London, UK. PARTICIPANTS--Altogether 374/468 (80%) of the children who had eaten lunch at the school on the day of the incident completed a questionnaire. MAIN RESULTS--There was a significant association between illness and the consumption of raw cucumber (relative risk = 6.1; 95% confidence interval 2.2, 16). Microbiological investigation of the foods served at lunch did not show any pathogens and toxicological investigations suggested that the cucumbers were contaminated by a pesticide. CONCLUSIONS--Although the outbreak displayed several typical features of mass psychogenic illness, the most probable cause was a toxic chemical present in cucumber served at lunch. Those responsible for investigating outbreaks of illness should be aware of the possible toxicological causes and the appropriate modes of investigation. They should be wary of too readily attributing a psychogenic cause to unusual outbreaks of acute illness in schoolchildren.

Skeletal age changes in puberty.

Buckler, J M
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /02/1984 EN
Relevância na Pesquisa
15.97%
Changes in skeletal age and height of 34 Leeds schoolboys were studied in a four year longitudinal survey covering puberty. Tanner and Whitehouse method TW2 was used. In each boy, skeletal age advanced rapidly during puberty, reaching a peak at an age related to that of peak height velocity. The importance of recognising that this acceleration of bone age is normal is stressed, in order to avoid attributing it to other causes.

Is attributing smoking to genetic causes associated with a reduced probability of quit attempt success? A cohort study

Wright, Alison J; Aveyard, Paul; Guo, Boliang; Murphy, Michael; Brown, Karen; Marteau, Theresa M
Fonte: Blackwell Publishing Ltd Publicador: Blackwell Publishing Ltd
Tipo: Artigo de Revista Científica
Publicado em /10/2007 EN
Relevância na Pesquisa
15.97%

Estimates for local and movement-based transmission of bovine tuberculosis in British cattle

Green, Darren M; Kiss, Istvan Z; Mitchell, Andrew P; Kao, Rowland R
Fonte: The Royal Society Publicador: The Royal Society
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
16.09%
Both badgers and livestock movements have been implicated in contributing to the ongoing epidemic of bovine tuberculosis (BTB) in British cattle. However, the relative contributions of these and other causes are not well quantified. We used cattle movement data to construct an individual (premises)-based model of BTB spread within Great Britain, accounting for spread due to recorded cattle movements and other causes. Outbreak data for 2004 were best explained by a model attributing 16% of herd infections directly to cattle movements, and a further 9% unexplained, potentially including spread from unrecorded movements. The best-fit model assumed low levels of cattle-to-cattle transmission. The remaining 75% of infection was attributed to local effects within specific high-risk areas. Annual and biennial testing is mandatory for herds deemed at high risk of infection, as is pre-movement testing from such herds. The herds identified as high risk in 2004 by our model are in broad agreement with those officially designated as such at that time. However, border areas at the edges of high-risk regions are different, suggesting possible areas that should be targeted to prevent further geographical spread of disease. With these areas expanding rapidly over the last decade...

Carpal tunnel syndrome

Aroori, Somaiah; Spence, Roy AJ
Fonte: The Ulster Medical Society Publicador: The Ulster Medical Society
Tipo: Artigo de Revista Científica
Publicado em /01/2008 EN
Relevância na Pesquisa
15.97%
Carpal tunnel syndrome is one of the most common peripheral neuropathies. It affects mainly middle aged women. In the majority of patients the exact cause and pathogenesis of CTS is unclear. Although several occupations have been linked to increased incidence and prevalence of CTS the evidence is not clear. Occupational CTS is uncommon and it is essential to exclude all other causes particularly the intrinsic factors such as obesity before attributing it to occupation. The risk of CTS is high in occupations involving exposure to high pressure, high force, repetitive work, and vibrating tools. The classic symptoms of CTS include nocturnal pain associated with tingling and numbness in the distribution of median nerve in the hand. There are several physical examination tests that will help in the diagnosis of CTS but none of these tests are diagnostic on their own. The gold standard test is nerve conduction studies. However, they are also associated with false positive and false negative results. The diagnosis of CTS should be based on history, physical examination and results of electrophysiological studies. The patient with mild symptoms of CTS can be managed with conservative treatment, particularly local injection of steroids. However...

Is serum gamma-glutamyl transferase a good marker of alcohol intake in stroke patients?

Peck, K.; Shinton, R.; Beevers, G.
Fonte: BMJ Group Publicador: BMJ Group
Tipo: Artigo de Revista Científica
Publicado em /09/1990 EN
Relevância na Pesquisa
15.97%
Serial serum gamma-glutamyl transferase (GGT) levels were estimated in 23 consecutive patients admitted to hospital with a diagnosis of acute stroke. The proportion of patients with elevated GGT levels in the initial, 36-hour and 72-hour samples was 13%, 30% and 24% respectively, suggesting a transient rise following a stroke. Patients with a history of diabetes mellitus had an initial serum GGT level 21 IU/l (95% confidence interval 6 to 37) higher than non-diabetics. We conclude that GGT levels after a stroke may reflect a history of diabetes and cerebral damage as well as the usual more established causes. Physicians, therefore, should be wary of attributing all unexplained high GGT levels in stroke patients to alcohol.

Sickle Cell Trait: An Update

Johnson, Lenworth N.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /08/1982 EN
Relevância na Pesquisa
15.97%
A review of the literature on sickle cell trait was completed by Sears in 1978. Since that time, several papers have been published concerning the possible health risks of sickle cell trait. Data presented from these studies show that there is no association with sickle cell trait and overall survival, overall mortality, overall morbidity, frequency and length of hospitalization, short-term survival of renal transplant recipient, and inheritance of glucose-6-phosphate dehydrogenase. Association with sickle cell trait is very likely in the following: splenic infarction at high altitudes (over 10,000 feet), in unpressurized airplane flight and mountain climbing, bacteriuria and pyelonephritis in pregnancy, hyposthenuria, hematuria, and delayed resolution of anterior chamber hyphema. Although these conditions have a statistical significant association with sickle cell trait, they occur quite infrequently. Thus, when they are observed, other causes should be sought before attributing them to sickle cell trait. Reduced mortality from Plasmodium falciparum infection also shows significant association with sickle cell trait.

Cultural Dimensions of Depression in Bangladesh: A Qualitative Study in Two Villages of Matlab

Selim, Nasima
Fonte: International Centre for Diarrhoeal Disease Research, Bangladesh Publicador: International Centre for Diarrhoeal Disease Research, Bangladesh
Tipo: Artigo de Revista Científica
Publicado em /02/2010 EN
Relevância na Pesquisa
16.09%
This article reports the results of a qualitative study conducted in two villages of Matlab to explore the cultural dimensions of depression. Participants included adult men and women with and without a history of depressive episode (n=42), formal and informal healthcare providers (n=6), and caregivers (n=2). Adults (n=10) with a history of depressive episode were selected from a 2005 survey conducted by ICDDR,B. A case vignette was used for eliciting local terms for depression, perceived causes, impact, and treatments. Hardly anyone recognized the term bishonnota (literal translation of depression) used in the past survey. The participants thought that the vignette was about chinta rog (worry illness), and they spoke of somatic symptoms in relation to this condition. When explored further, they mentioned sadness and psychological complaints. Men felt that it affected them more while women felt the opposite. They associated chinta rog with poverty and social issues with impacts on marriage, work, and education. From their responses, it seemed that they preferred a psychosocial framework attributing the cause to thoughts and emotions, resulting from social causes. Commonly-suggested treatments were more income, better relationships...

Agency Attribution in Infancy: Evidence for a Negativity Bias

Hamlin, J. Kiley; Baron, Andrew S.
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
Publicado em 06/05/2014 EN
Relevância na Pesquisa
16.22%
Adults tend to attribute agency and intention to the causes of negative outcomes, even if those causes are obviously mechanical. Is this over-attribution of negative agency the result of years of practice with attributing agency to actual conspecifics, or is it a foundational aspect of our agency-detection system, present in the first year of life? Here we present two experiments with 6-month-old infants, in which they attribute agency to a mechanical claw that causes a bad outcome, but not to a claw that causes a good outcome. Control experiments suggest that the attribution stems directly from the negativity of the outcome, rather than from physical cues present in the stimuli. Together, these results provide evidence for striking developmental continuity in the attribution of agency to the causes of negative outcomes.

Spectrum of Histomorphologic Findings in Liver in Patients with SLE: A Review

Grover, Shrruti; Rastogi, Archana; Singh, Jyotsna; Rajbongshi, Apurba; Bihari, Chhagan
Fonte: Hindawi Publishing Corporation Publicador: Hindawi Publishing Corporation
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
16.09%
Collagen vascular diseases (CVDs) like systemic lupus erythematosus (SLE), rheumatoid arthritis, Sjogren syndrome (SS), and scleroderma are immunologically mediated disorders that typically have multisystem involvement. Although clinically significant liver involvement is rare, liver enzyme abnormalities are common in these patients. The reported prevalence of hepatic involvement in SLE, histopathologic findings, and its significance is very variable in the existing literature. It is important to be familiar with the causes of hepatic involvement in SLE along with histomorphological features which aid in distinguishing hepatitis of SLE from other hepatic causes as they would alter the patient management and disease course. Histopathology of liver in SLE shows a wide morphological spectrum commonly due to a coexisting pathology. Drug induced hepatitis, viral etiology, and autoimmune overlap should be excluded before attributing the changes to SLE itself. Common histopathologic findings in SLE include fatty liver, portal inflammation, and vascular changes like hemangioma, congestion, nodular regenerative hyperplasia, arteritis, and abnormal vessels in portal tracts.

Attributing Changes in Global Sulfur Emissions

Stern, David I
Fonte: Universidade Nacional da Austrália Publicador: Universidade Nacional da Austrália
Tipo: Working/Technical Paper Formato: 189540 bytes; application/pdf
EN_AU
Relevância na Pesquisa
26.09%
The environmental Kuznets curve (EKC) hypothesis proposes that there is an inverted U-shape relation between environmental degradation and income per capita. Explanations for this pattern include proximate variables such as input-output structure that mediate the effects of underlying causes such as changing comparative advantage or increased environmental awareness with higher incomes. A number of studies have tested individual factors that might explain the EKC. But a systematic allocation of changes in environmental impacts or degradation has not been attempted. Stern and Common (1999) show that there are omitted variables in a global sulfur EKC that may result in biased estimates of the EKC in non-random samples of countries. In this study we develop a method to systematically "attribute" changes in emissions to the major proximate causes of the EKC relationship: change in input mix, change in output mix, scale, and technical change. We apply the attribution method to the panel data set used by Stern and Common. The results show that though input and output mix are statistically significant they make only a small contribution to changes in global emissions. Increasing scale and countervailing technical change explain most of the observed change. However...

Attributions of causes for unemployment by unemployed workers

Bendassolli, Pedro Fernando; Universidade Federal do Rio Grande do Norte; Guedes Gondim, Sonia Maria; Universidade Federal da Bahia; Coelho-Lima, Fellipe; Universidade Federal do Rio Grande do Norte
Fonte: ISPA - Instituto Universitário Publicador: ISPA - Instituto Universitário
Tipo: Artigo de Revista Científica Formato: application/pdf
Publicado em 30/06/2015 POR
Relevância na Pesquisa
56.52%
This study investigated the assignment of causes for unemployment by unemployed workers, with a view to analyzing the predictive power of sociodemographic variables for the assignment. A scale of causal attribution of unemployment, originally developed by Furnham, was applied to 376 unemployed people. After confirmatory factor analysis (CFA), the scale factors were used in a regression model containing sociodemographic variables as predictors. The CFA results support Furnham’s original three-factor model of unemployment causes (individualistic, societal, and fatalistic; χ2(100) = 261.53, p < 0.001; χ2/gl = 2.61; CFI = 0.91, TLI = 0.90; RMSEA = 0.06). Regression analysis identified significant prediction for only the income variable and individualistic causes factor (β = 0.15, p < 0.01), the income variable and societal causes factor (β = 0.10, p < 0.001), and the educational level variable and societal causes factor (β = -0.15, p < 0.01). Societal causes presented the highest average score, which was significantly (p < 0.001) different than the scores for the other two factors. The study concludes that educational level does not seem to have a linear impact on beliefs regarding the causes for unemployment, nor does gender have a significant influence on these beliefs. Keywords: unemployment; attributing causes; Furnham’s scale

Soil Erosion in a Highly Dynamic, Terraced Environment - The Effect of the Three Gorges Dam in China

Schönbrodt-Stitt, Sarah
Fonte: Universität Tübingen Publicador: Universität Tübingen
Tipo: Dissertation; info:eu-repo/semantics/doctoralThesis
EN
Relevância na Pesquisa
16.09%
Worldwide, soil erosion is one of the most pressing environmental problems of present times. Particularly, soil erosion triggered by overland flow and runoff seriously affects the productivity and stability of ecosystems. The loss of fertile topsoil and soil's water storage capacity, and the discharge of sediments and associated contamination of waterbodies due to diffuse matter transport of particle-bounded agrochemicals from cropland highly elicit call a for action to combat soil erosion for a future securing of food supply and high drinking water quality. Globally, China belongs to one of those countries most affected by soil erosion. Technical problems as well as high economic off-site damages and costs resulting from reservoir siltation and thus, reduced project's lifespan due to soil erosion are typical for numerous large-scale dam projects in China. In addition to the natural disposition to soil erosion, especially, anthropogenic impacts associated to the dam construction distinctly affect the soil erosion risk potential in the adjacent ecosystems. This can be exemplarily seen at the currently worldwide largest dam project, the Three Gorges Dam at the Yangtze River in Central China. This megaproject has been controversially discussed since its planning...

Perceived modifiability of self-blame attributions for negative life events : implications for well-being /

Correy, Brenda L.
Fonte: Brock University Publicador: Brock University
Tipo: Electronic Thesis or Dissertation
ENG
Relevância na Pesquisa
16.39%
Research suggests that self-blame attributions are important in the process of adjustment to negative life events. Much of the research originates from JanofTBulman's (1979) theory regarding behavioural and characterological self-blame. She argued that attributing negative events to one's behaviour is adaptive because behavioural self-blame involves attributions to a modifiable source, which implies that a similar event can be avoided in the future. In contrast, attributing negative events to one's character is believed to be maladaptive because character is seen as relatively stable and unmodifiable. Unfortunately, the empirical literature does not show consistent relations between these two types of self-blame attributions and well-being as predicted by Janoff-Bulman. For this thesis, I proposed that one reason for this inconsistency is that Janoff-Bulman's assumption about the perceived modifiability of behavioural versus characterological causes is incorrect — people often dlo perceive character (as well as behaviour) to be modifiable. Sixty-two participants completed a questionnaire regarding a recent negative life event and its impact on their well-being. Consistent with my argument, I found that both behavioural and characterological self-blame attributions following a negative life event were seen as modifiable. As hypothesized...

Carbon-based secondary and structural compounds in Mediterranean shrubs growing near a natural CO2 spring

Peñuelas, Josep; Castells Caballé, Eva; Joffre, R.; Tognetti, Roberto
Fonte: Universidade Autônoma de Barcelona Publicador: Universidade Autônoma de Barcelona
Tipo: Artigo de Revista Científica Formato: application/pdf
Publicado em //2002 ENG
Relevância na Pesquisa
16.09%
We studied carbon-based secondary and structural compounds (CBSSCs) in Myrtus communis, Erica arborea, and Juniperus communis co-occurring in a natural CO2 spring site and in a nearby control site in a Mediterranean environment. Leaf concentrations of phenolics and CBSSCs, such as lignin, cellulose, and hemicellulose, total nonstructural carbohydrates (TNCs), and lipids were measured monthly (phenolics) and every two months (the other compounds) throughout a year. There was a slight seasonal trend towards maximum concentrations of most of these CBSSCs during autumn–winter and minimum values during the spring season, particularly in Myrtus communis. For most of the CBSSCs and species, there were no consistent or significant patterns in response to the elevated [CO2] (c. 700 μmol mol−1) of the spring site. These results were not due to a dilution effect by increased structural or nonstructural carbon. Therefore, in contrast to many experimental studies of CO2 enrichment, mainly conducted for short periods, there were no greater concentrations of phenolics, and, as in many of these studies, there were neither greater concentrations of the other CBSSCs. These results do not agree with the predictions of the carbon source-sink hypotheses. Possible causes of this disagreement are discussed. These causes include the complex heterogeneous environmental conditions and the variability of resource availabilities in the field...

Attributions of causes for unemployment by unemployed workers

Bendassolli,Pedro F.; Gondim,Sonia Maria Guedes; Coelho-Lima,Fellipe
Fonte: Instituto Superior de Psicologia Aplicada Publicador: Instituto Superior de Psicologia Aplicada
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/2015 EN
Relevância na Pesquisa
46.27%
This study investigated the assignment of causes for unemployment by unemployed workers, with a view to analyzing the predictive power of sociodemographic variables for the assignment. A scale of causal attribution of unemployment, originally developed by Furnham, was applied to 376 unemployed people. After confirmatory factor analysis (CFA), the scale factors were used in a regression model containing sociodemographic variables as predictors. The CFA results support Furnham’s original three-factor model of unemployment causes (individualistic, societal, and fatalistic; χ2(100)=261.53, p<0.001; χ2/gl=2.61; CFI=0.91, TLI=0.90; RMSEA=0.06). Regression analysis identified significant prediction for only the income variable and individualistic causes factor (β=0.15, p<0.01), the income variable and societal causes factor (β=0.10, p<0.001), and the educational level variable and societal causes factor (β=-0.15, p<0.01). Societal causes presented the highest average score, which was significantly (p<0.001) different than the scores for the other two factors. The study concludes that educational level does not seem to have a linear impact on beliefs regarding the causes for unemployment, nor does gender have a significant influence on these beliefs.