Página 1 dos resultados de 17 itens digitais encontrados em 0.031 segundos

Perception of Rhizobium nodulation factors by tomato cells and inactivation by root chitinases.

Staehelin, C; Granado, J; Müller, J; Wiemken, A; Mellor, R B; Felix, G; Regenass, M; Broughton, W J; Boller, T
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em 15/03/1994 EN
Relevância na Pesquisa
15.71%
The bacterial genera Rhizobium and Bradyrhizobium, nitrogen-fixing symbionts of legumes, secrete specific lipo-chitooligosaccharides that induce the formation of nodules on their host plants. When preparations of such nodulation-inducing factors (Nod factors) were added to suspension-cultured tomato cells, a rapid and transient alkalinization of the culture medium occurred. Lipo-oligosaccharide preparations from Rhizobium or Bradyrhizobium treated with flavonoids, known inducers of Nod factor synthesis, were up to 100 times more potent in inducing alkalinization than the ones from untreated bacteria. The activity was absent from preparations of the mutant strain Rhizobium sp. NGR234 delta nodABC, unable to produce any Nod factors. Preparations of Nod factors from various bacteria as well as individual, highly purified Nod factors from Rhizobium sp. NGR(pA28) induced alkalinization in the tomato cell cultures at nanomolar concentrations. This demonstrates that Nod factors can be perceived by tomato, a nonhost of rhizobia. Using the alkalinization response as a sensitive bioassay, Nod factors were found to be inactivated by plant chitinases. Root chitinases purified from different legumes differed in their potential to inactivate differently substituted Nod factors produced by Rhizobium sp. NGR(pA28). This indicates that the specificity of the bacterium-host plant interaction may be due...

Mucopolysaccharide in the blood of a patient with neuroblastoma

Broughton, P. M. G.; Dykes, J. R. W.; Holt, Shirley; Ridley, J. W.; Steel, A. E.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /04/1970 EN
Relevância na Pesquisa
15.76%
In a case of neuroblastoma the presence of an abnormal blood constituent was suspected from the raised erythrocyte sedimentation rate, sludging of the red cells, marked rouleaux formation, an atypical Leishman stain, increased plasma viscosity, and a distorted protein electrophoresis pattern. The abnormal constituent was shown to be a mucopolysaccharide which was either hyaluronic acid or chondroitin sulphate.

Presentation of malignant pleural mesothelioma with cerebral metastases.

McNaughton, W M; Broughton, M E; Toner, G C; Schwarz, M A
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /07/1990 EN
Relevância na Pesquisa
25.71%

Safety Precautions to be Observed with Cooled Premixed Gases

Bracken, A.; Broughton, G. B.; Hill, D. W.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em 21/09/1968 EN
Relevância na Pesquisa
15.71%
The gas delivered from a cylinder of Entonox (50% nitrous oxide and 50% oxygen) may not contain adequate quantities of oxygen if the cylinder has been cooled and then allowed to warm up in a vertical position.

Toll-like Receptor 9–Dependent and –Independent Dendritic Cell Activation by Chromatin–Immunoglobulin G Complexes

Boulé, Melissa W.; Broughton, Courtney; Mackay, Fabienne; Akira, Shizuo; Marshak-Rothstein, Ann; Rifkin, Ian R.
Fonte: The Rockefeller University Press Publicador: The Rockefeller University Press
Tipo: Artigo de Revista Científica
Publicado em 21/06/2004 EN
Relevância na Pesquisa
35.75%
Dendritic cell (DC) activation by nucleic acid–containing immunoglobulin (Ig)G complexes has been implicated in systemic lupus erythematosus (SLE) pathogenesis. However, the mechanisms responsible for activation and subsequent disease induction are not completely understood. Here we show that murine DCs are much more effectively activated by immune complexes that contain IgG bound to chromatin than by immune complexes that contain foreign protein. Activation by these chromatin immune complexes occurs by two distinct pathways. One pathway involves dual engagement of the Fc receptor FcγRIII and Toll-like receptor (TLR)9, whereas the other is TLR9 independent. Furthermore, there is a characteristic cytokine profile elicited by the chromatin immune complexes that distinguishes this response from that of conventional TLR ligands, notably the induction of BAFF and the lack of induction of interleukin 12. The data establish a critical role for self-antigen in DC activation and explain how the innate immune system might drive the adaptive immune response in SLE.

Modeling Parasite Dynamics on Farmed Salmon for Precautionary Conservation Management of Wild Salmon

Rogers, Luke A.; Peacock, Stephanie J.; McKenzie, Peter; DeDominicis, Sharon; Jones, Simon R. M.; Chandler, Peter; Foreman, Michael G. G.; Revie, Crawford W.; Krkošek, Martin
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
Publicado em 05/04/2013 EN
Relevância na Pesquisa
25.75%
Conservation management of wild fish may include fish health management in sympatric populations of domesticated fish in aquaculture. We developed a mathematical model for the population dynamics of parasitic sea lice (Lepeophtheirus salmonis) on domesticated populations of Atlantic salmon (Salmo salar) in the Broughton Archipelago region of British Columbia. The model was fit to a seven-year dataset of monthly sea louse counts on farms in the area to estimate population growth rates in relation to abiotic factors (temperature and salinity), local host density (measured as cohort surface area), and the use of a parasiticide, emamectin benzoate, on farms. We then used the model to evaluate management scenarios in relation to policy guidelines that seek to keep motile louse abundance below an average three per farmed salmon during the March–June juvenile wild Pacific salmon (Oncorhynchus spp.) migration. Abiotic factors mediated the duration of effectiveness of parasiticide treatments, and results suggest treatment of farmed salmon conducted in January or early February minimized average louse abundance per farmed salmon during the juvenile wild salmon migration. Adapting the management of parasites on farmed salmon according to migrations of wild salmon may therefore provide a precautionary approach to conserving wild salmon populations in salmon farming regions.

Hardarson, G. and Broughton, W. J. Maximising the use of biological nitrogen fixation in agriculture

SPRENT, J. I.
Fonte: Oxford University Press Publicador: Oxford University Press
Tipo: Artigo de Revista Científica
Publicado em /04/2004 EN
Relevância na Pesquisa
15.71%

Mapping and QTL analysis of the barley population Alexis x Sloop

Barr, A.; Jefferies, S.; Broughton, S.; Chalmers, K.; Kretschmer, J.; Boyd, W.; Collins, H.; Roumeliotis, S.; Logue, S.; Coventry, S.; Moody, D.; Read, B.; Poulsen, D.; Lance, R.; Platz, G.; Park, R.; Panozzo, J.; Karakousis, A.; Lim, P.; Verbyla, A.; et
Fonte: C S I R O Publishing Publicador: C S I R O Publishing
Tipo: Artigo de Revista Científica
Publicado em //2003 EN
Relevância na Pesquisa
15.71%
Two populations between the German malting variety Alexis and the Australian malting variety Sloop were constructed, mapped, phenotyped, and subjected to quantitative trait loci analysis. One population consisted of 153 F4-derived recombinant inbred lines and the other of 111 doubled haploid lines. This paper describes 18 field and laboratory experiments conducted with the populations and summarises the traits mapped and analysed. The genetic basis of 5 traits (malt extract, resistance to leaf rust, resistance to powdery mildew, early flowering, plant stature) important to Australian efforts to improve malting barley varieties was elucidated. Detailed maps for these populations are shown in this paper, while a consensus map incorporating these maps and further experiments on the populations are described elsewhere in this issue.

Inter Varsity Rifle Team 1948

Fonte: Universidade de Adelaide Publicador: Universidade de Adelaide
Tipo: Imagem
Publicado em //1948
Relevância na Pesquisa
15.75%
Back: A.D.Tonkin, R.Broughton, G.Danks, M.C.Kempe, G.V.Harry. Front: J.H.Michael, C.J.Starling(pres), M.P.Wallace(capt), J.R.Moritz. Absent: C.Fuller, W.Scammell. Held in Adelaide, won by Adelaide. Adelaide 2128; Melb 2065; Syd 2061; Tas 2017; Qld 1992; WA 1874; black and white; mounted

Inter Varsity Rifle Team 1949

Fonte: Universidade de Adelaide Publicador: Universidade de Adelaide
Tipo: Imagem
Publicado em //1949
Relevância na Pesquisa
15.75%
Back: J.H.Michael, A.Tonkin, M.Wallace, G.Danks. Front: K.Milne, C.Fuller, B.Berry, R.W.Broughton, P.C.Toope, G.Harry. Held in Tasmania, won by Melbourne; Adelaide 4th.; Black and white; mounted

The GM-CSF receptor family: mechanism of activation and implications for disease

Hercus, T.; Broughton, S.; Ekert, P.; Ramshaw, H.; Perugini, M.; Grimbaldeston, M.; Woodcock, J.; Thomas, D.; Pitson, S.; Hughes, T.; D'Andrea, R.; Parker, M.; Lopez, A.
Fonte: Taylor & Francis Ltd Publicador: Taylor & Francis Ltd
Tipo: Artigo de Revista Científica
Publicado em //2012 EN
Relevância na Pesquisa
25.89%
Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a pluripotent cytokine produced by many cells in the body, which regulates normal and malignant hemopoiesis as well as innate and adaptive immunity. GM-CSF assembles and activates its heterodimeric receptor complex on the surface of myeloid cells, initiating multiple signaling pathways that control key functions such as cell survival, cell proliferation, and functional activation. Understanding the molecular composition of these pathways, the interaction of the various components as well as the kinetics and dose-dependent mechanics of receptor activation provides valuable insights into the function of GM-CSF as well as the related cytokines, interleukin-3 and interleukin-5. This knowledge provides opportunities for the development of new therapies to block the action of these cytokines in hematological malignancy and chronic inflammation.; Timothy R. Hercus, Sophie E. Broughton, Paul G. Ekert,Hayley S. Ramshaw, Michelle Perugini, Michele Grimbaldeston, Joanna M. Woodcock, Daniel Thomas, Stuart Pitson, Timothy Hughes, Richard J. D’andrea, Michael W. Parker, & Angel F. Lopez

Signalling by the βc family of cytokines; Signalling by the beta c family of cytokines

Hercus, T.; Dhagat, U.; Kan, W.; Broughton, S.; Nero, T.; Perugini, M.; Sandow, J.; D'Andrea, R.; Ekert, P.; Hughes, T.; Parker, M.; Lopez, A.
Fonte: Elsevier Sci Ltd Publicador: Elsevier Sci Ltd
Tipo: Artigo de Revista Científica
Publicado em //2013 EN
Relevância na Pesquisa
25.94%
The GM-CSF, IL-3 and IL-5 family of cytokines, also known as the βc family due to their receptors sharing the signalling subunit βc, regulates multiple biological processes such as native and adaptive immunity, inflammation, normal and malignant hemopoieis, and autoimmunity. Australian scientists played a major role in the discovery and biological characterisation of the βc cytokines and their recent work is revealing unique features of cytokine receptor assembly and signalling. Furthermore, specific antibodies have been generated to modulate their function. Characterisation of the structural and dynamic requirements for the activation of the βc receptor family and the molecular definition of downstream signalling pathways are providing new insights into cytokine receptor signalling as well as new therapeutic opportunities.; Timothy R. Hercus, Urmi Dhagat, Winnie L.T. Kan, Sophie E. Broughton, Tracy L. Nero, Michelle Perugini, Jarrod J. Sandow, Richard J. D’Andrea, Paul G. Ekert, Timothy Hughes, Michael W. Parker, Angel F. Lopez

The Catholic church in the Australian colonies, 1840-1865

Suttor, Timothy Lachlan Lautour
Fonte: Universidade Nacional da Austrália Publicador: Universidade Nacional da Austrália
Tipo: Thesis (PhD); Doctor of Philosophy (PhD)
EN_AU
Relevância na Pesquisa
35.71%
In the century or so beginning 1776 European communities all over the world were politically remoulded in terms of the Enlightenment politique: the sovereignty of the multitude realised in legislatures of elected representatives, and even ( in some cases) in an elected executive. Now this development was congenial to Catholic thinking, as the future Pius VII declared when Napoleon first upturned the status quoante in Italy. For instance, election and representation and consultation with the governed dominate the entire constitution of several of the mediaeval religious orders which flourish to this day. In 1800, however, the Catholic West had to rediscover this thomist tradition - the diffusion of responsibility under the aegis of the natural law - after the centuries of practical and theoretical authoritarianism introduced by, and in response to, the Protestant revolt. O’Connell managed this in Ireland, between 1800 and 1814-0 ; Bishop England ( more than any other) spread the good news in the United States; McEncroe ( more than any other) in Australia But there was in all these men a pronounced tendency to mobilise the Catholic vote by an explicit appeal to a combination of national and religious loyalties very effective...

Society and thought in eastern Australia, 1835-1851

Roe, Michael
Fonte: Universidade Nacional da Austrália Publicador: Universidade Nacional da Austrália
Tipo: Thesis (PhD)
EN
Relevância na Pesquisa
66.07%
661 p; The thesis deals with the colonies of New South Wales and Van Diemen’s Land; it begins when J.T. Bigge's ideal had come to crisis, and ends with the gold rushes. By "J.T. Bigge's ideal” is meant a society in which the Church of England and a land-owning elite joined with the executive government to establish a way of life, both hierarchical and harmonious. The Church and the gentry respectively comprise the core of the first two chapters, which describe the ideology and strength of colonial conservatism. In the former the central figure is W.G. Broughton, first Anglican bishop in Australia and remarkably sensitive to the difficulties which beset the conservative ideal. His beliefs and insight shape not only this chapter but the whole thesis. Following a description of the typical Anglican reaction to the major features of colonial life, particular emphasis is placed on the Church's attempt to assert its opinion sometimes through, sometimes against the power of the State. Here, as at many other places throughout the thesis, the education issue becomes very prominent. The Church appears as the strongest bastion of conservative thought, denouncing every aspect of society which made for change and disruption. Although not numerous...

Decomposição open book generalizada em conjuntos semi-algébricos; Open book structures on semi-algebraic manifols

Santo, Antonio Andrade do Espírito
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 05/12/2014 PT
Relevância na Pesquisa
16.08%
Nos últimos anos, váarios pesquisadores tais como: A. Bodin, A. Dimca, A. Durfee, A. Jacquemard, A. Menegon Neto, A. Némethi, A. Pichon, A. Verjovsky, A. Zaharia, D. Siersma, H. A. Hamm, D. Massey, H. Aguilar-Cabrera, H. H. Vui, J. Cisneros, J. Seade, J. Snoussi, L. D. Tráng, L. Paunescu, L. R. Dias, M. A. S. Ruas, M. Oka, M. Tibar, N. Dutertre, R. N. Araújo dos Santos, S. A. Broughton, T. Gaffney, Y. Chen, entre outros, têm apresentado generalizações dos Teoremas de fibrações de Milnor no ambiente real e complexo (e do Teorema de Kurdyka-Orro-Simon, ver por exemplo [Di, KOS]), visando um melhor entendimento de propriedades topológicas locais e globais das singularidades. Nesta direção de pesquisa esses autores tem utilizado várias ferramentas e técnicas de diversas áreas da matemática. O que mostra a riqueza e a complexidade destes estudos e acrescenta, em nossa modesta opinião, um aspecto que é ao mesmo tempo interessante e desafiador. Neste trabalho, mostraremos como estender as fibrações de Milnor em esferas no caso local e global, real e complexo, para uma aplicação C2-semi-algébrica F = (f1, . . . , fp) : RN → Rp e uma variedade W ⊂ RN semi-algébrica com possível singularidade. Com tal objetivo...

Exo-Oligosaccharides of Rhizobium sp. Strain NGR234 Are Required for Symbiosis with Various Legumes

Staehelin, Christian; Forsberg, Lennart S.; D'Haeze, Wim; Gao, Mu-Yun; Carlson, Russell W.; Xie, Zhi-Ping; Pellock, Brett J.; Jones, Kathryn M.; Walker, Graham C.; Streit, Wolfgang R.; Broughton, William J.
Fonte: American Society for Microbiology Publicador: American Society for Microbiology
Tipo: Artigo de Revista Científica
Publicado em /09/2006 EN
Relevância na Pesquisa
25.77%
Rhizobia are nitrogen-fixing bacteria that establish endosymbiotic associations with legumes. Nodule formation depends on various bacterial carbohydrates, including lipopolysaccharides, K-antigens, and exopolysaccharides (EPS). An acidic EPS from Rhizobium sp. strain NGR234 consists of glucosyl (Glc), galactosyl (Gal), glucuronosyl (GlcA), and 4,6-pyruvylated galactosyl (PvGal) residues with β-1,3, β-1,4, β-1,6, α-1,3, and α-1,4 glycoside linkages. Here we examined the role of NGR234 genes in the synthesis of EPS. Deletions within the exoF, exoL, exoP, exoQ, and exoY genes suppressed accumulation of EPS in bacterial supernatants, a finding that was confirmed by chemical analyses. The data suggest that the repeating subunits of EPS are assembled by an ExoQ/ExoP/ExoF-dependent mechanism, which is related to the Wzy polymerization system of group 1 capsular polysaccharides in Escherichia coli. Mutation of exoK (NGRΩexoK), which encodes a putative glycanase, resulted in the absence of low-molecular-weight forms of EPS. Analysis of the extracellular carbohydrates revealed that NGRΩexoK is unable to accumulate exo-oligosaccharides (EOSs), which are O-acetylated nonasaccharide subunits of EPS having the formula Gal(Glc)5(GlcA)2PvGal. When used as inoculants...

Results of two multi-chord stellar occultations by dwarf planet (1) Ceres

Gomes-Júnior, A. R.; Giacchini, B. L.; Braga-Ribas, F.; Assafin, M.; Vieira-Martins, R.; Camargo, J. I. B.; Sicardy, B.; Timerson, B.; George, T.; Broughton, J.; Blank, T.; Benedetti-Rossi, G.; Brooks, J.; Dantowitz, R. F.; Dunham, D. W.; Dunham, J. B.;
Fonte: Universidade Cornell Publicador: Universidade Cornell
Tipo: Artigo de Revista Científica
Relevância na Pesquisa
15.71%
We report the results of two multi-chord stellar occultations by the dwarf planet (1) Ceres that were observed from Brazil on 2010 August 17, and from the USA on 2013 October 25. Four positive detections were obtained for the 2010 occultation, and nine for the 2013 occultation. Elliptical models were adjusted to the observed chords to obtain Ceres' size and shape. Two limb fitting solutions were studied for each event. The first one is a nominal solution with an indeterminate polar aspect angle. The second one was constrained by the pole coordinates as given by Drummond et al. Assuming a Maclaurin spheroid, we determine an equatorial diameter of 972 $\pm$ 6 km and an apparent oblateness of 0.08 $\pm$ 0.03 as our best solution. These results are compared to all available size and shape determinations for Ceres made so far, and shall be confirmed by the NASA's Dawn space mission.; Comment: 9 pages, 6 figures. Accepted for publication in MNRAS