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Validation of structural heterogeneity in Cryo-EM datasets by cluster ensembles= : Validação de heterogeneidade estrutural em dados de Crio-ME por comitês de agrupadores; Validação de heterogeneidade estrutural em dados de Crio-ME por comitês de agrupadores

Ricardo Diogo Righetto
Fonte: Biblioteca Digital da Unicamp Publicador: Biblioteca Digital da Unicamp
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 08/08/2014 PT
Relevância na Pesquisa
46.14%
Análise de Partículas Isoladas é uma técnica que permite o estudo da estrutura tridimensional de proteínas e outros complexos macromoleculares de interesse biológico. Seus dados primários consistem em imagens de microscopia eletrônica de transmissão de múltiplas cópias da molécula em orientações aleatórias. Tais imagens são bastante ruidosas devido à baixa dose de elétrons utilizada. Reconstruções 3D podem ser obtidas combinando-se muitas imagens de partículas em orientações similares e estimando seus ângulos relativos. Entretanto, estados conformacionais heterogêneos frequentemente coexistem na amostra, porque os complexos moleculares podem ser flexíveis e também interagir com outras partículas. Heterogeneidade representa um desafio na reconstrução de modelos 3D confiáveis e degrada a resolução dos mesmos. Entre os algoritmos mais populares usados para classificação estrutural estão o agrupamento por k-médias, agrupamento hierárquico, mapas autoorganizáveis e estimadores de máxima verossimilhança. Tais abordagens estão geralmente entrelaçadas à reconstrução dos modelos 3D. No entanto, trabalhos recentes indicam ser possível inferir informações a respeito da estrutura das moléculas diretamente do conjunto de projeções 2D. Dentre estas descobertas...

A questão salarial revisitada : exército industrial de reserva e heterogeneidade estrutural; The wage question revisited : industrial reserve army and structural heterogeneity

Gustavo José Danieli Zullo
Fonte: Biblioteca Digital da Unicamp Publicador: Biblioteca Digital da Unicamp
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 23/10/2014 PT
Relevância na Pesquisa
46.03%
O objetivo desta dissertação consiste em evidenciar que a economia brasileira está estruturalmente baseada em um baixo padrão de remuneração. Inicialmente amparados pela discussão sobre a marginalidade social, quando no primeiro capítulo fazemos um breve balanço do debate travado nos anos 1970 sobre suas origens econômicas, buscamos sintetizar as diferentes posições sobre os efeitos que a dominação do capital monopolista exerceu sobre o mercado de trabalho. Desse debate surgem duas concepções distintas e que, consequentemente, redundam em metodologias diferentes para quantificar a heterogeneidade que é própria de economias dependentes e de origem colonial, como a brasileira. A primeira dessas, que examinamos analiticamente no segundo capítulo, distingue as formas de trabalho em duas categorias: formal e informal. Sobre essa abordagem, antes de salientarmos de forma direta as deficiências inerentes a tal classificação, destacamos que alguns de seus pressupostos não estavam balizados pela formação econômico-social do país. Pensada dentro de um arcabouço teórico que julgava que o desenvolvimento capitalista brasileiro seria suficiente para homogeneizar as estruturas econômicas e sociais, essa concepção subestima a dependência como uma força que delimita as potencialidades nacionais. Por outro lado...

Numerical Characterization of Concrete Heterogeneity

Pitangueira,Roque Luiz; Silva,Raul Rosas e
Fonte: ABM, ABC, ABPol Publicador: ABM, ABC, ABPol
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/09/2002 EN
Relevância na Pesquisa
36.17%
In this paper, a finite element model including both material heterogeneity and size effects is presented. The concrete is considered as a statistical combination of constituent phase with different properties (aggregate, mortar and interface material). The material point response is based on a combination of the random occurrence of the solid phases in the structural volume as well as on the differences of structural response due to the size effect. Such combination allows for higher or lower heterogeneity corresponding to smaller or larger structural size. Simulations of the material heterogeneity and associated size effect in a computationally efficient and simple manner show good qualitative agreement with available experimental results for the three-point bending and Brazilian split tests.

Investigation of the structural heterogeneity of lipooligosaccharides from pathogenic Haemophilus and Neisseria species and of R-type lipopolysaccharides from Salmonella typhimurium by electrospray mass spectrometry.

Gibson, B W; Melaugh, W; Phillips, N J; Apicella, M A; Campagnari, A A; Griffiss, J M
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /05/1993 EN
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36.17%
Heterogeneity in the lipooligosaccharides (LOS) of pathogenic Haemophilus and Neisseria species is evident from the multiplicity of components observed with electrophoretic analyses. Knowledge of the precise structures that make up these diverse LOS molecules is clearly the key to reaching an understanding of pathogenic processes such as phase variation and molecular mimicry. Except for a few cases, little is known about the specific structural features of LOS that underlie phase variation and molecular mimicry, partly because of the inherent difficulties in the structural elucidation of these complex glycolipids. In the lipopolysaccharides (LPS) from Salmonella typhimurium and Escherichia coli, rough, or R-type, mutants have been isolated that have provided insight into the biosynthetic pathways and associated genetics that control LPS expression. Nonetheless, recent work has shown that these R-type LPS are more complex than originally thought, and significant heterogeneity is still observed, primarily in their phosphorylation states. In order to investigate the structures of LPS and LOS in a more rapid fashion, we have determined the precise molecular weights of LOS (and LPS) preparations from various Haemophilus, Neisseria, and Salmonella species by electrospray ionization-mass spectrometry. The LOS (or LPS) were first O-deacylated under mild hydrazine conditions to remove O-linked esters primarily from the lipid A portion. Under negative-ion conditions...

Development of structural heterogeneity of mitochondria in mouse hepatocytes.

Kanamura, S; Kanai, K; Watanabe, J; Asada-Kubota, M; Oka, M
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /09/1984 EN
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45.95%
The volume and shape (the axial ratio:length/diameter) of mitochondria in periportal and perihepatic hepatocytes from newborn, 5 days old, 10 days old and adult male ddY mice were analysed by quantitative electron microscopy. In newborn animals, the volume and relative histogram of the axial ratio were not significantly different between periportal and perihepatic cells. Thereafter, the volume did not change significantly in periportal cells, whereas it decreased between 5 days of age and the adult in perihepatic cells. In adult animals, the volume in perihepatic cells was 26% of that in periportal cells. The relative histogram of the axial ratio for periportal cells deviated significantly to smaller values than in that for perihepatic cells in 5 days old, 10 days old and adult animals. Thus, the structural heterogeneity of hepatocyte mitochondria, evident in adult animals, is not present in newborn animals but arises during postnatal development.

A Spectroscopic Study of Structural Heterogeneity and Carbon Monoxide Binding in Neuroglobin

Nienhaus, Karin; Nienhaus, G. Ulrich
Fonte: Kluwer Academic Publishers Publicador: Kluwer Academic Publishers
Tipo: Artigo de Revista Científica
Publicado em /12/2005 EN
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46.04%
Neuroglobin (Ngb) is a small globular protein that binds diatomic ligands like oxygen, carbon monoxide (CO) and nitric oxide at a heme prosthetic group. We have performed FTIR spectroscopy in the infrared stretching bands of CO and flash photolysis with monitoring in the electronic heme absorption bands to investigate structural heterogeneity at the active site of Ngb and its effects on CO binding and migration at cryogenic temperatures. Four CO stretching bands were identified; they correspond to discrete conformations that differ in structural details and CO binding properties. Based on a comparison of bound-state and photoproduct IR spectra of the wild-type protein, Ngb distal pocket mutants and myoglobin, we have provided structural interpretations of the conformations associated with the different CO bands. We have also studied ligand migration to the primary docking site, B. Rebinding from this site is governed by very low enthalpy barriers (∼1 kJ/mol), indicating an extremely reactive heme iron. Moreover, we have observed ligand migration to a secondary docking site, C, from which CO rebinding involves higher enthalpy barriers.

Structural Heterogeneity Modulates Effective Refractory Period: A Mechanism of Focal Arrhythmia Initiation

Bishop, Martin J.; Connolly, Adam; Plank, Gernot
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
Publicado em 07/10/2014 EN
Relevância na Pesquisa
46.23%
Reductions in electrotonic loading around regions of structural and electrophysiological heterogeneity may facilitate capture of focal triggered activity, initiating reentrant arrhythmias. How electrotonic loading, refractoriness and capture of focal ectopics depend upon the intricate nature of physiological structural anatomy, as well as pathological tissue remodelling, however, is not well understood. In this study, we performed computational bidomain simulations with anatomically-detailed models representing the rabbit left ventricle. We used these models to quantify the relationship between local structural anatomy and spatial heterogeneity in action potential (AP) characteristics, electrotonic currents and effective refractory periods (ERPs) under pacing and restitution protocols. Regions surrounding vessel cavities, in addition to tissue surfaces, had significantly lower peak downstream electrotonic currents than well coupled myocardium ( vs A/cm2), with faster maximum AP upstroke velocities ( vs mV/ms), although noticeably very similar APDs ( vs ms) and AP restitution properties. Despite similarities in APDs, ERPs in regions of low electrotonic load in the vicinity of surfaces, intramural vessel cavities and endocardial structures were up to ms shorter compared to neighbouring well-coupled tissue...

Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization

Bueno-Orovio, Alfonso; Kay, David; Grau, Vicente; Rodriguez, Blanca; Burrage, Kevin
Fonte: The Royal Society Publicador: The Royal Society
Tipo: Artigo de Revista Científica
Publicado em 06/08/2014 EN
Relevância na Pesquisa
46.13%
Impulse propagation in biological tissues is known to be modulated by structural heterogeneity. In cardiac muscle, improved understanding on how this heterogeneity influences electrical spread is key to advancing our interpretation of dispersion of repolarization. We propose fractional diffusion models as a novel mathematical description of structurally heterogeneous excitable media, as a means of representing the modulation of the total electric field by the secondary electrical sources associated with tissue inhomogeneities. Our results, analysed against in vivo human recordings and experimental data of different animal species, indicate that structural heterogeneity underlies relevant characteristics of cardiac electrical propagation at tissue level. These include conduction effects on action potential (AP) morphology, the shortening of AP duration along the activation pathway and the progressive modulation by premature beats of spatial patterns of dispersion of repolarization. The proposed approach may also have important implications in other research fields involving excitable complex media.

Structural heterogeneity and functional diversity of topologically associating domains in mammalian genomes

Wang, Xiao-Tao; Dong, Peng-Fei; Zhang, Hong-Yu; Peng, Cheng
Fonte: Oxford University Press Publicador: Oxford University Press
Tipo: Artigo de Revista Científica
EN
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46.1%
Recent chromosome conformation capture (3C) derived techniques have revealed that topologically associating domain (TAD) is a pervasive element in chromatin three-dimensional (3D) organization. However, there is currently no parameter to quantitatively measure the structural characteristics of TADs, thus obscuring our understanding on the structural and functional differences among TADs. Based on our finding that there exist intrinsic chromatin interaction patterns in TADs, we define a theoretical parameter, called aggregation preference (AP), to characterize TAD structures by capturing the interaction aggregation degree. Applying this defined parameter to 11 Hi-C data sets generated by both traditional and in situ Hi-C experimental pipelines, our analyses reveal that heterogeneous structures exist among TADs, and this structural heterogeneity is significantly correlated to DNA sequences, epigenomic signals and gene expressions. Although TADs can be stable in genomic positions across cell lines, structural comparisons show that a considerable number of stable TADs undergo significantly structural rearrangements during cell changes. Moreover, the structural change of TAD is tightly associated with its transcription remodeling. Altogether...

Heterogeneidade estrutural na indústria Goiana, 2000-2010; Structural heterogeneity in the industry of Goiás, 2000-2010

Aguiais, Edilson Gonçalves de
Fonte: Universidade Federal de Goiás; Brasil; UFG; Programa de Pós-graduação em Agronegócio (EAEA); Escola de Agronomia e Engenharia de Alimentos - EAEA (RG) Publicador: Universidade Federal de Goiás; Brasil; UFG; Programa de Pós-graduação em Agronegócio (EAEA); Escola de Agronomia e Engenharia de Alimentos - EAEA (RG)
Tipo: Dissertação Formato: application/pdf
POR
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66.27%
The purpose of this study is to understand to what extent the phenomenon of structural heterogeneity existing in Goiás industrial economy has affected the structure of earnings and employment in the state of Goiás in the interregnum from 2000 to 2010 . The hypothesis put forward is that, in Goiás, the process of growth of industrial production and the number of companies has developed so as to increase productivity gap and labor income among different segments of the manufacturing industry in the period 2000-2010. To perform the proposed work goal, we used the technical resources of literature and documents and adopted the descriptive analytical method. The first analysis is a comparison between the structure of the transformation of Goiás and São Paulo industry and the results indicated a reduction in structural heterogeneity, both indicators of labor productivity as in the structure of earnings and employment. The second test checks the industrial conformation as the level of technology embodied in the production process. At this point, the segments of low technological intensity remained the largest share of the value added by the manufacturing industry, indicating that driving the dynamic axis of Goiás economy facing the external sector...

Determinants of structural heterogeneity in Mexican manufacturing industry, 1994-2008

Vázquez López, Raúl
Fonte: CEPAL - Comissão Econômica para a América Latina e o Caribe Publicador: CEPAL - Comissão Econômica para a América Latina e o Caribe
EN
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46.08%
Includes bibliography; This article analyses the stagnation of productivity and the increasing structural heterogeneity of Mexican manufacturing industry in the period 1994-2008. Traditional indicators of dispersion are estimated for 200 activity classes, 50 branches and nine divisions of the manufacturing sector; and these corroborate the widening disparity in productive efficiency between globalized activities and traditional industries that has been reported in other papers. The study also provides a more detailed account of the intensification of this trend in the first decade of the present century and the specific characteristics of within-sector heterogeneity. Other results obtained using a shift-share technique show that structural change contributes very little to productivity growth, and that technological progress is concentrated in just a few activities that engage with the domestic economy in a variety of ways. Nonetheless, these activities have weak local linkages and add little value to the content of the goods they make.

Padrões de heterogeneidade estrutural no Brasil; Patterns of structural heterogeneity in Brazil

José Geraldo Portugal Junior
Fonte: Biblioteca Digital da Unicamp Publicador: Biblioteca Digital da Unicamp
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 10/12/2012 PT
Relevância na Pesquisa
46.17%
O trabalho "Padrões de Heterogeneidade Estrutural no Brasil" procura analisar os problemas do emprego das economias periféricas que se industrializaram com intensidade no pós-guerra, tomando a economia brasileira como caso paradigmático. Os conceitos de "Heterogeneidade Estrutural" e "Subemprego" constituem a base conceitual da pesquisa, desenvolvida no sentido de evidenciar as especificidades da absorção de força de trabalho ao longo da industrialização brasileira. Ou seja, nega que a economia seja uma ciência formada por teorias e conceitos de validade universal e que, portanto, requer desenvolvimentos analíticos específicos para situações específicas. A base conceitual da pesquisa é operacionalizada a partir dos dados dos Censos Demográficos e das PNADs realizados pelo IBGE, procurando mostrar como a heterogeneidade e o subemprego, indicadores da absorção de população economicamente ativa em condições de baixa produtividade do trabalho, perpetuam-se como marcas das transformações da estrutura ocupacional ao longo do tempo, paralelamente à crescente ponderação assumida pela ocupação de elevada produtividade do trabalho. Dividiu-se o período analisado, de 1960 a 2009, de modo a evidenciar as características assumidas pela heterogeneidade estrutural que...

Strong frequency dependence of vibrational relaxation in bulk and surface water reveals sub-picosecond structural heterogeneity

van der Post, Sietse T.; Hsieh, Cho-Shuen; Okuno, Masanari; Nagata, Yuki; Bakker, Huib J.; Bonn, Mischa; Hunger, Johannes
Fonte: Nature Pub. Group Publicador: Nature Pub. Group
Tipo: Artigo de Revista Científica
Publicado em 18/09/2015 EN
Relevância na Pesquisa
46.08%
Because of strong hydrogen bonding in liquid water, intermolecular interactions between water molecules are highly delocalized. Previous two-dimensional infrared spectroscopy experiments have indicated that this delocalization smears out the structural heterogeneity of neat H2O. Here we report on a systematic investigation of the ultrafast vibrational relaxation of bulk and interfacial water using time-resolved infrared and sum-frequency generation spectroscopies. These experiments reveal a remarkably strong dependence of the vibrational relaxation time on the frequency of the OH stretching vibration of liquid water in the bulk and at the air/water interface. For bulk water, the vibrational relaxation time increases continuously from 250 to 550 fs when the frequency is increased from 3,100 to 3,700 cm−1. For hydrogen-bonded water at the air/water interface, the frequency dependence is even stronger. These results directly demonstrate that liquid water possesses substantial structural heterogeneity, both in the bulk and at the surface.

On the correlation between microscopic structural heterogeneity and embrittlement behavior in metallic glasses

Li, Weidong; Gao, Yanfei; Bei, Hongbin
Fonte: Nature Publishing Group Publicador: Nature Publishing Group
Tipo: Artigo de Revista Científica
Publicado em 05/10/2015 EN
Relevância na Pesquisa
46.01%
In order to establish a relationship between microstructure and mechanical properties, we systematically annealed a Zr-based bulk metallic glass (BMG) at 100 ~ 300 °C and measured their mechanical and thermal properties. The as-cast BMG exhibits some ductility, while the increase of annealing temperature and time leads to the transition to a brittle behavior that can reach nearly-zero fracture energy. The differential scanning calorimetry did not find any significant changes in crystallization temperature and enthalpy, indicating that the materials still remained fully amorphous. Elastic constants measured by ultrasonic technique vary only slightly with respect to annealing temperature and time, which does obey the empirical relationship between Poisson’s ratio and fracture behavior. Nanoindentation pop-in tests were conducted, from which the pop-in strength mapping provides a “mechanical probe” of the microscopic structural heterogeneities in these metallic glasses. Based on stochastically statistic defect model, we found that the defect density decreases with increasing annealing temperature and annealing time and is exponentially related to the fracture energy. A ductile-versus-brittle behavior (DBB) model based on the structural heterogeneity is developed to identify the physical origins of the embrittlement behavior through the interactions between these defects and crack tip.

Structural heterogeneity and its role in determining properties of disordered solids

Tong, Hua; Xu, Ning
Fonte: Universidade Cornell Publicador: Universidade Cornell
Tipo: Artigo de Revista Científica
Publicado em 14/02/2014
Relevância na Pesquisa
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We construct a new order parameter from the normal modes of vibration, based on the consideration of energy equipartition, to quantify the structural heterogeneity in disordered solids. The order parameter exhibits strong spatial correlations with low-temperature single particle dynamics and local structural entropy. To characterize the role of particles with the most defective local structures identified by the order parameter, we pin them and study how properties of disordered solids respond to the pinning. It turns out that these particles are responsible to the quasilocalized low-frequency vibration, instability, softening, and nonaffinity of disordered solids.; Comment: 5 pages, 4 figures

Sampling bias in systems with structural heterogeneity and limited internal diffusion

Onnela, Jukka-Pekka; Johnson, Neil F.; Gourley, Sean; Reinert, Gesine; Spagat, Michael
Fonte: Universidade Cornell Publicador: Universidade Cornell
Tipo: Artigo de Revista Científica
Relevância na Pesquisa
45.95%
Complex systems research is becomingly increasingly data-driven, particularly in the social and biological domains. Many of the systems from which sample data are collected feature structural heterogeneity at the mesoscopic scale (i.e. communities) and limited inter-community diffusion. Here we show that the interplay between these two features can yield a significant bias in the global characteristics inferred from the data. We present a general framework to quantify this bias, and derive an explicit corrective factor for a wide class of systems. Applying our analysis to a recent high-profile survey of conflict mortality in Iraq suggests a significant overestimate of deaths.

Dynamics-Driven Evolution to Structural Heterogeneity in Complex Networks

Shao, Zhen; Zhou, Haijun
Fonte: Universidade Cornell Publicador: Universidade Cornell
Tipo: Artigo de Revista Científica
Relevância na Pesquisa
46.01%
The mutual influence of dynamics and structure is a central issue in complex systems. In this paper we study by simulation slow evolution of network under the feedback of a local-majority-rule opinion process. If performance-enhancing local mutations have higher chances of getting integrated into its structure, the system can evolve into a highly heterogeneous small-world with a global hub (whose connectivity is proportional to the network size), strong local connection correlations and power law-like degree distribution. Networks with better dynamical performance are achieved if structural evolution occurs much slower than the network dynamics. Structural heterogeneity of many biological and social dynamical systems may also be driven by various dynamics-structure coupling mechanisms.; Comment: Figure 2 updated. Final version as appear in Physica A

Caracterización de la heterogeneidad estructural en polipropileno polimórfico mediante espectroscopia vibracional: microscopia IR y Raman; Caracterization of structural heterogeneity in polymorphic polypropylene by vibrational spectroscopy: IR and Raman microscopy

Ellis, Gary James; Marco, C.; Gómez, M. A.; Blancas, C:
Fonte: Sociedad Española de Cerámica y Vidrio Publicador: Sociedad Española de Cerámica y Vidrio
Tipo: Artículo Formato: 701989 bytes; application/pdf
SPA
Relevância na Pesquisa
56.03%
[ES] Una serie de muestras polimórficas de polipropileno isotáctico, obtenidos por nucleación selectiva, fueron estudiadas mediante espectroscopia vibracional. Se observó una correlación entre los espectros obtenidos y el parámetro de Turner-Jones, característico de la fracción del polimorfo β. Se evaluaron aspectos de la heterogeneidad estructural utilizando técnicas de mapeo con microscopia IR, microscopia Raman confocal, microscopia IR con radiación sincrotrón y microscopia IR de imagen.; [EN] A series of polymorphic samples of isotactic polypropylene, obtained via selective nucleation, were studied by vibrational spectroscopy. A correlation was observed between the spectra obtained and the Turner-Jones parameter, characteristic of the fraction of the β polymorph. Aspects of the structural heterogeneity in the samples were evaluated using mapping techniques with IR micrsocopy, confocal Raman microscopy, synchrotron IR microscopy and IR imaging microscopy.; Este estudio ha sido financiado por la CICYT, MAT-98-0194. Agradecemos a la Comunidad Europea “Enhancing Access to Research Infrastructures”, Proyecto IM008-02 para acceso al sincrotrón de LURE, así como Prof. Paul Dumas por su ayuda. Acceso al sincrotrón de DESY fue subvencionado por la EU en el Proyecto IHP-HRRICT- 1999-00040.; Peer reviewed

Conformational Heterogeneity of a Multifunctional Protein

Deis, Lindsay N.
Fonte: Universidade Duke Publicador: Universidade Duke
Tipo: Dissertação
Publicado em //2015
Relevância na Pesquisa
36.26%

The structural plasticity conferred by conformational flexibility has increasingly been recognized as a likely determinant of function. For example, multiscale heterogeneity in the calmodulin central helix most likely helps it in binding over 100 protein targets, and a concerted motion seen in both nuclear magnetic resonance (NMR) and crystal structures of ubiquitin is proposed to underlie its functional plasticity of promiscuous binding to many different proteins with high affinity. However, flexibility is manifested in a variety of ways, depending both on the protein itself and on how it is observed. Conformational heterogeneity (the term we use for flexibility when studied by X-ray crystallography) is evident in electron density, either as fully separated peaks or as anisotropic density shapes showing fluctuation of atom groupings. Many phenomena contribute to conformational heterogeneity in crystal structures, from diverse crystal contacts to functionally relevant conformational fluctuations on a wide range of time and size scales.

In addition to ubiquitin and calmodulin, the Staphylococcus aureus virulence factor staphylococcal protein A (SpA) is an example of a highly heterogeneous protein. SpA is a major contributor to bacterial evasion of the host immune system...

Structural Heterogeneity in Santa Catarina's Industry; Heteorogeneidade estrutural na indústria catarinense

Cândido, Carolina Silvestre; Universidade Federal do Rio Grande do Sul; Perin, Fernanda Steiner; Universidade Federal de Santa Catarina; Cário, Silvio Antônio Ferraz; Universidade Federal de Santa Catarina
Fonte: UFSC Publicador: UFSC
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; Artigo Avaliado pelos Pares Formato: application/pdf
Publicado em 01/12/2013 POR
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This paper has as main goal to study the Santa Catarina’s industrial structural heterogeneity in a comparison with the Brazilian industry in order to contribute with the studies about the economics reality of Santa Catarina, identifying its relation with innovation and verifying the existence of a productive convergence. The Cepal’s economics theory presents, through the ideas of Aníbal Pinto, the structural heterogeneity as a result of the unequal generation and diffusion of the technical progress within a productive structure. The structural heterogeneity takes place in the internal productive gap that means the existence, in one productive structure, of developed and undeveloped productive sectors with different levels of productivity. The unequal generation and diffusion of the technical progress generates different levels of labor productivity that reflects in unequal wages and opportunities of access to information, knowledge aggravating the social inequality. Through the analyzes, from 1996 to 2011, of Industrial Transformation Value and Employed Persons data it is possible to calculate the labor productivity as a proxy for productive and structural heterogeneity – as proposed by IPEA (2011) – and observing it through the Industrial Newsletter of Industry and Trade – BIC – proposed by APEX – it is possible to prove the existence of structural heterogeneity in the Santa Catarina’s and Brazilian Industry...