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Systematic review of the effects of fatigue on spatiotemporal gait parameters

Barbieri, Fabio Augusto; Dos Santos, Paulo Cezar Rocha; Lirani-Silva, Ellen; Vitório, Rodrigo; Gobbi, Lilian Teresa Bucken; Van Diëen, Jaap H.
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Artigo de Revista Científica Formato: 125-131
ENG
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PURPOSE: This systematic review aimed to assess changes on spatiotemporal gait parameters due to fatigue. MATERIAL AND METHOD: A search was carried out in literature published from 1950 to December 2010 and retrieved 771 articles using terms referring to walking and fatigue in the title, abstract or keywords. Two researchers assessed the selection and quality of each article independently. RESULTS: Seven studies were selected for this systematic review, two of which reported on the same data set. Several spatiotemporal parameters were reported to change with fatigue, but the few variables studied in multiple studies, gait speed and stride or step length and stride time, were affected only in single studies. Fatigue appears to modulate spatiotemporal gait parameters, but the effects of fatigue appear to be dependent on the muscles that were fatigued, and age that appears to be a moderator of the effects of fatigue on gait. © 2013 - IOS Press and the authors. All rights reserved.

Spatiotemporal epidemiology in the identification of critical areas: an application to tuberculosis

Nunes, Carla; Gomes, Dulce; Filipe, Patrícia; Areias, Cristiana; Sousa, Bruno; Briz, Teodoro
Fonte: European Journal of Epidemiology, Vol.27, Supplement 1, p.S149 Publicador: European Journal of Epidemiology, Vol.27, Supplement 1, p.S149
Tipo: Artigo de Revista Científica
POR
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The increasing relevance of spatiotemporal epidemiology, enhanced by a greater availability of geographical information and the growing importance of knowing where, when and how the health phenomena occurred in a spatiotemporal context, promotes more scientifically robust and effective early intervention. The identification of critical areas, either in terms of their higher incidence of a disease, or their intensity of determinants, is crucial to assess them for priorities setting.

Cartographic representation of spatiotemporal phenomena

Correia, Filipe Laginha Pinto
Fonte: Faculdade de Ciências e Tecnologia Publicador: Faculdade de Ciências e Tecnologia
Tipo: Dissertação de Mestrado
Publicado em //2013 ENG
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Dissertação para obtenção do Grau de Mestre em Engenharia Informática; The field of geovisual analytics focuses on visualization techniques to analyze spatial data by enhancing human cognition. However, spatial data also has a temporal component that is practically disregarded when using conventional geovisual analytic tools. Some proposals have been made for techniques to analyze spatiotemporal data, but most were made for specific use cases, and are hard to abstract for other situations. There was a need to create a method to describe and compare the existing techniques. A catalog that provides a clear description of a set of techniques that deal with spatiotemporal data is proposed. This allows the identification of the most useful techniques depending on the required criteria. The description of a technique in the catalog relies on the two frameworks proposed. The first framework is used for describing spatiotemporal datasets resorting to data scenarios, a class of datasets. Twenty three data scenarios are described using this framework. The second framework is used for describing analytical tasks on spatiotemporal data, nine different tasks are described using this framework. Also, in this document, is the proposal of two new geovisual analytical techniques that can be applied to spatiotemporal data: the attenuation & accumulation map technique and the overlapping spatiotemporal windows technique. A prototype was developed that implements both techniques as a proof of concept.

SPATIOTEMPORAL TRENDS OF CASES OF PANDEMIC INFLUENZA A(H1N1)PDM09 IN ARGENTINA, 2009-2012

LEVEAU,Carlos M.; UEZ,Osvaldo; VACCHINO,Marta N.
Fonte: Instituto de Medicina Tropical Publicador: Instituto de Medicina Tropical
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/04/2015 EN
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The aim of this paper was to analyze the spatiotemporal variations of cases of influenza A(H1N1)pdm09 in Argentina. A space-time permutation scan statistic was performed to test the non-randomness in the interaction between space and time in reported influenza A(H1N1)pdm09 cases. In 2009, two clusters were recorded in the east of Buenos Aires Province (May and June) and in the central and northern part of Argentina (July and August). Between 2011 and 2012, clusters near areas bordering other countries were registered. Within the clusters, in 2009, the high notification rates were first observed in the school-age population and then extended to the older population (15-59 years). From 2011 onwards, higher rates of reported cases of influenza A(H1N1)pdm09 occurred in children under five years in center of the country. Two stages of transmission of influenza A(H1N1)pdm09 can be characterized. The first stage had high rates of notification and a possible interaction with individuals from other countries in the major cities of Argentina (pattern of hierarchy), and the second stage had an increased interaction in some border areas without a clear pattern of hierarchy. These results suggest the need for greater coordination in the Southern Cone countries...

Spatiotemporal analysis of reported cases of acute Chagas disease in the State of Pernambuco, Brazil, from 2002 to 2013

Santos,Fred Luciano Neves; Lorena,Virginia Maria Barros de; Souza,Wayner Vieira de; Gomes,Yara de Miranda
Fonte: Sociedade Brasileira de Medicina Tropical - SBMT Publicador: Sociedade Brasileira de Medicina Tropical - SBMT
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/04/2015 EN
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INTRODUCTION: Control strategies to eliminate the transmission of Chagas disease by insect vectors have significantly decreased the number of reported acute cases in Brazil. However, data regarding the incidence and distribution of acute Chagas disease cases in the State of Pernambuco are unavailable in the literature. METHODS: A geographical information system was used to delineate the spatiotemporal distribution profile of the cases from 2002 to 2013 in 185 municipalities of Pernambuco based on the municipality where notification occurred. The results were presented in digital maps generated by the TerraView software (INPE). RESULTS: A total of 302 cases of acute disease were recorded in 37.8% of the municipalities, for a total of 0.13 cases per 1,000,000 inhabitants per year. Out of the 302 cases, 99.3% were reported between 2002 and 2006. The most affected municipalities were Carnaubeira da Penha, Mirandiba and Terra Nova. The risk maps showed a significant decrease in the number of notifications and a concentration of cases in the Midwest region. CONCLUSIONS: This study highlights a significant decrease in new cases of acute Chagas disease in Pernambuco starting in 2006 when Brazil received an international certification for the interruption of vectorial transmission by Triatoma infestans. However...

Time-space Kriging to address the spatiotemporal misalignment in the large datasets

Liang, Dong; Kumar, Naresh
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
EN
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This paper presents a Bayesian hierarchical spatiotemporal method of interpolation, termed as Markov Cube Kriging (MCK). The classical Kriging methods become computationally prohibitive, especially for large datasets due to the O(n3) matrix decomposition. MCK offers novel and computationally efficient solutions to address spatiotemporal misalignment, mismatch in the spatiotemporal scales and missing values across space and time in large spatiotemporal datasets. MCK is flexible in that it allows for non-separable spatiotemporal structure and nonstationary covariance at the hierarchical spatiotemporal scales. Employing MCK we developed estimates of daily concentration of fine particulates matter ≤2.5 μm in aerodynamic diameter (PM2.5) at 2.5 km spatial grid for the Cleveland Metropolitan Statistical Area, 2000 to 2009. Our validation and cross-validation suggest that MCK achieved robust prediction of spatiotemporal random effects and underlying hierarchical and nonstationary spatiotemporal structure in air pollution data. MCK has important implications for environmental epidemiology and environmental sciences for exposure quantification and collocation of data from different sources, available at different spatiotemporal scales.

A Toolbox for Spatiotemporal Analysis of Voltage-Sensitive Dye Imaging Data in Brain Slices

Bourgeois, Elliot B.; Johnson, Brian N.; McCoy, Almedia J.; Trippa, Lorenzo; Cohen, Akiva S.; Marsh, Eric D.
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
Publicado em 26/09/2014 EN
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27.01%
Voltage-sensitive dye imaging (VSDI) can simultaneously monitor the spatiotemporal electrical dynamics of thousands of neurons and is often used to identify functional differences in models of neurological disease. While the chief advantage of VSDI is the ability to record spatiotemporal activity, there are no tools available to visualize and statistically compare activity across the full spatiotemporal range of the VSDI dataset. Investigators commonly analyze only a subset of the data, and a majority of the dataset is routinely excluded from analysis. We have developed a software toolbox that simplifies visual inspection of VSDI data, and permits unaided statistical comparison across spatial and temporal dimensions. First, the three-dimensional VSDI dataset (x,y,time) is geometrically transformed into a two-dimensional spatiotemporal map of activity. Second, statistical comparison between groups is performed using a non-parametric permutation test. The result is a 2D map of all significant differences in both space and time. Here, we used the toolbox to identify functional differences in activity in VSDI data from acute hippocampal slices obtained from epileptic Arx conditional knock-out and control mice. Maps of spatiotemporal activity were produced and analyzed to identify differences in the activity evoked by stimulation of each of two axonal inputs to the hippocampus: the perforant pathway and the temporoammonic pathway. In mutant hippocampal slices...

Predicting Chronic Fine and Coarse Particulate Exposures Using Spatiotemporal Models for the Northeastern and Midwestern United States

Yanosky, Jeff D.; Suh MacIntosh, Helen H.; Paciorek, Christopher Joseph
Fonte: National Institute of Environmental Health Sciences Publicador: National Institute of Environmental Health Sciences
Tipo: Artigo de Revista Científica
EN_US
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Background: Chronic epidemiologic studies of particulate matter (PM) are limited by the lack of monitoring data, relying instead on citywide ambient concentrations to estimate exposures. This method ignores within-city spatial gradients and restricts studies to areas with nearby monitoring data. This lack of data is particularly restrictive for fine particles (PM with aerodynamic diameter < 2.5 μm; PM2.5) and coarse particles (PM with aerodynamic diameter 2.5–10 μm; PM10–2.5), for which monitoring is limited before 1999. To address these limitations, we developed spatiotemporal models to predict monthly outdoor PM2.5 and PM10–2.5 concentrations for the northeastern and midwestern United States. Methods: For PM2.5, we developed models for two periods: 1988–1998 and 1999–2002. Both models included smooth spatial and regression terms of geographic information system-based and meteorologic predictors. To compensate for sparse monitoring data, the pre-1999 model also included predicted PM10 (PM with aerodynamic diameter < 10 μm) and extinction coefficients (km−1). PM10–2.5 levels were estimated as the difference in monthly predicted PM10 and PM2.5, with predicted PM10 from our previously developed PM10 model. Results: Predictive performance for PM2.5 was strong (cross-validation R2 = 0.77 and 0.69 for post-1999 and pre-1999 PM2.5 models...

Spatiotemporal variation of the abundance of calcareous green macroalgae in the Florida Keys: A study of synchrony within a macroalgal functional-form group

Collado-Vides, Ligia; Rutten, Leanne M.; Fourqurean, James W.
Fonte: FIU Digital Commons Publicador: FIU Digital Commons
Tipo: Artigo de Revista Científica
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The abundance of calcareous green algae was recorded quarterly at 28 sites within the Florida Keys National Marine Sanctuary (FKNMS) for a period of 7 years as part of a sea grass monitoring program. To evaluate the validity of using the functional-form group approach, we designed a sampling method that included the functional-form group and the component genera. This strategy enabled us to analyze the spatiotemporal patterns in the abundance of calcareous green algae as a group and to describe synchronous behavior among its genera through the application of a nonlinear regression model to both categories of data. Spatial analyses revealed that, in general, all genera displayed long-term trends of increasing abundance at most sites; however, at some sites the long-term trends for genera opposed one another. Strong synchrony in the timing of seasonal changes was found among all genera, possibly reflecting similar reproductive and seasonal growth pattern, but the variability in the magnitude of seasonal changes was very high among genera and sites. No spatial patterns were found in long-term or seasonal changes; the only significant relation detected was for slope, with sites closer to land showing higher values, suggesting that some factors associated with land proximity are affecting this increase. We conclude that the abundances of genera behaved differently from the functional-form group...

The spatiotemporal trajectory of a dengue epidemic in a medium-sized city

Morato,Daniela G; Barreto,Florisneide R; Braga,José U; Natividade,Marcio S; Costa,Maria da Conceição N; Morato,Vanessa; Teixeira,Maria da Glória Lima Cruz
Fonte: Instituto Oswaldo Cruz, Ministério da Saúde Publicador: Instituto Oswaldo Cruz, Ministério da Saúde
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/2015 EN
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Understanding the transmission dynamics of infectious diseases is important to allow for improvements of control measures. To investigate the spatiotemporal pattern of an epidemic dengue occurred at a medium-sized city in the Northeast Region of Brazil in 2009, we conducted an ecological study of the notified dengue cases georeferenced according to epidemiological week (EW) and home address. Kernel density estimation and space-time interaction were analysed using the Knox method. The evolution of the epidemic was analysed using an animated projection technique. The dengue incidence was 6.918.7/100,000 inhabitants; the peak of the epidemic occurred from 8 February-1 March, EWs 6-9 (828.7/100,000 inhabitants). There were cases throughout the city and was identified space-time interaction. Three epicenters were responsible for spreading the disease in an expansion and relocation diffusion pattern. If the health services could detect in real time the epicenters and apply nimbly control measures, may possibly reduce the magnitude of dengue epidemics.

Three-dimensional structures of the spatiotemporal nonlinear Schrödinger equation with power-law nonlinearity in PT-symmetric potentials

Dai, Chao-Qing; Wang, Yan
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica Formato: 8 pages
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The spatiotemporal nonlinear Schrödinger equation with power-law nonlinearity in PT-symmetric potentials is investigated, and two families of analytical three-dimensional spatiotemporal structure solutions are obtained. The stability of these solutions is tested by the linear stability analysis and the direct numerical simulation. Results indicate that solutions are stable below some thresholds for the imaginary part of PT-symmetric potentials in the self-focusing medium, while they are always unstable for all parameters in the self-defocusing medium. Moreover, some dynamical properties of these solutions are discussed, such as the phase switch, power and transverse power-flow density. The span of phase switch gradually enlarges with the decrease of the competing parameter k in PT-symmetric potentials. The power and power-flow density are all positive, which implies that the power flow and exchange from the gain toward the loss domains in the PT cell.; Funded by the National Natural Science Foundation of China (Grant No. 11375007), the Zhejiang Provincial Natural Science Foundation of China (Grant No. LY13F050006).

Integration of Satellite Remote Sensing and Ground-based Measurement for Modelling the Spatiotemporal Distribution of Fine Particulate Matter at a Regional Scale

Tian, JIE
Fonte: Quens University Publicador: Quens University
Tipo: Tese de Doutorado Formato: 142157882 bytes; application/pdf
EN; EN
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36.75%
Accurate information on the spatial-temporal distributions of air pollution at a regional scale is crucial for effective air quality control, as well as to impact studies on local climate and public health. The current practice of mapping air quality relies heavily on data from monitoring stations, which are often quite sparse and irregularly spaced. The research presented in this dissertation seeks to advance the methodologies involved in spatiotemporal analysis of air quality that integrates remotely-sensed data and in situ measurement. Aerosol optical depth (AOD) data from the Moderate Resolution Imaging Spectroradiometer (MODIS) is analyzed to estimate fine particulate matter (PM2.5) concentrations as the target air pollutant. The spatial-temporal distribution of columnar aerosol loading is investigated through mapping MODIS AOD in southern Ontario, Canada throughout 2004. Clear distribution patterns and strong seasonality are found for the study area. There is a detectable relationship between an AOD level and underlying land use structure and topography on the ground. MODIS AOD was correlated with the ground-level PM2.5 concentration (GL-[PM2.5]) at various wavelengths. The AOD-PM2.5 correlation is found to be sensitive to spatial-temporal scale changes. Further...

Spatiotemporal surface Ginzburg-Landau solitons

Mihalache, Dumitru; Mazilu, Dumitru; Lederer, Falk; Kivshar, Yuri
Fonte: American Physical Society Publicador: American Physical Society
Tipo: Artigo de Revista Científica
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We study spatiotemporal light localization in truncated one-dimensional arrays of optical waveguides in the presence of gain and loss. We demonstrate the existence of classes of continuous-discrete spatiotemporal Ginzburg-Landau solitons, which include th

Exponential localization of singular vectors in spatiotemporal chaos

Pazó, Diego; López, Juan M.; Rodríguez, Miguel A.
Fonte: American Physical Society Publicador: American Physical Society
Tipo: Artículo Formato: 228441 bytes; application/pdf
ENG
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5 pages, 4 figures.-- PACS nrs.: 05.45.Jn; 05.40.-a; 05.45.Ra; 92.60.Wc.; In a dynamical system the singular vector (SV) indicates which perturbation will exhibit maximal growth after a time interval τ. We show that in systems with spatiotemporal chaos the SV exponentially localizes in space. Under a suitable transformation, the SV can be described in terms of the Kardar-Parisi-Zhang equation with periodic noise. A scaling argument allows us to deduce a universal power law τ(−γ) for the localization of the SV. Moreover the same exponent γ characterizes the finite-τ deviation of the Lyapunov exponent in excellent agreement with simulations. Our results may help improve existing forecasting techniques.; Financial support from the Ministerio de Educación y Ciencia (Spain) under Projects No. FIS2006-12253-C06-04 and No. CGL2007-64387/CLI is acknowledged. D.P. acknowledges the support by CSIC under the Junta de Ampliación de Estudios Programme (JAE-Doc).; Peer reviewed

Structure of characteristic Lyapunov vectors in spatiotemporal chaos

Pazó, Diego; Szendro, Ivan Georg; López, Juan M.; Rodríguez, Miguel A.
Fonte: American Physical Society Publicador: American Physical Society
Tipo: Artículo Formato: 342630 bytes; application/pdf
ENG
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9 pages, 4 figures.-- PACS nrs.: 05.45.Jn; 05.40.-a; 05.45.Ra.; We study Lyapunov vectors (LVs) corresponding to the largest Lyapunov exponents in systems with spatiotemporal chaos. We focus on characteristic LVs and compare the results with backward LVs obtained via successive Gram-Schmidt orthonormalizations. Systems of a very different nature such as coupled-map lattices and the (continuous-time) Lorenz `96 model exhibit the same features in quantitative and qualitative terms. Additionally, we propose a minimal stochastic model that reproduces the results for chaotic systems. Our work supports the claims about universality of our earlier results [I. G. Szendro et al., Phys. Rev. E 76, 025202(R) (2007)] for a specific coupled-map lattice.; Financial support from the Ministerio de Educación y Ciencia (Spain) under projects FIS2006-12253-C06-04 and CGL2007-64387/CLI is acknowledged. D.P. acknowledges support by MEC (Spain) through the "Juan de la Cierva" Programme.; Peer reviewed

Characterization of spatiotemporal chaos in an inhomogeneous active medium

Bouzat, Sebastián; Wio, Horacio S.; Mindlin, G. B.
Fonte: Elsevier Publicador: Elsevier
Tipo: Pre-print Formato: 409792 bytes; application/pdf
ENG
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13 pages, 6 figs.-- Physica D (in press).-- Digital.CSIC post-print version available: http://digital.csic.es/handle/10261/7507; We study a reaction diffusion system of the activator-inhibitor type with inhomogeneous reaction terms showing spatiotemporal chaos. We analyze the topological properties of the unstable periodic orbits in the slow chaotic dynamics appearing, which can be embedded in three dimensions. We perform a bi-orthogonal decomposition analyzing the minimum number of modes necessary to find the same organization of unstable orbits.; Partial support from ANPCyT and UBACyT, Argentine agencies, is acknowledged. HSW thanks the MECyD, Spain, for an award within the Sabbatical Program for Visiting Professors, and to the Universitat de les Illes Balears for the kind hospitality extended to him.; Peer reviewed

Investigating the Spatiotemporal Links Between Disorder, Crime, and the Fear of Crime

Doran, Bruce; Lees, Brian G
Fonte: Blackwell Publishing Ltd Publicador: Blackwell Publishing Ltd
Tipo: Artigo de Revista Científica
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While links between social and physical disorder, crime, and the fear of crime have long been areas of research interest, few studies have looked at these links from a spatiotemporal viewpoint. This is somewhat surprising, as many of the factors associated with disorder, crime, and fear are known to vary over time and space. This paper uses GISystems to investigate potential spatiotemporal links between these areas in Wollongong, New South Wales, with specific focus on links between graffiti and the fear of crime. The results reveal that the distribution of fear of crime varies considerably over time and is often spatially coincident with concentrations of disorder. Graffiti was found to be one of the most prevalent types of physical disorder. The results are discussed in the context of the "broken windows" thesis and strategic intervention at the community level.

OBJECTS, ACTIONS AND NATURAL PROCESSES: FROM SPATIOTEMPORAL MARKERS FOR THE SOCIALENVIRONMENTAL MEMORIES; OBJETOS, AÇÕES E PROCESSOS NATURAIS: DE MARCADORES ESPAÇO-TEMPORAIS À MEMÓRIAS SOCIOAMBIENTAIS

Loiola, Sérgio Almeida; Oliveira, Sandra Fátima; Ratts, Alecsandro
Fonte: Universidade de São Paulo. Faculdade de Filosofia, Letras e Ciências Humanas Publicador: Universidade de São Paulo. Faculdade de Filosofia, Letras e Ciências Humanas
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; Artigo Avaliado pelos Pares Formato: application/pdf
Publicado em 20/07/2011 POR
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Este trabalho busca dar continuidade à elaboração de uma perspectiva complexa na geografia. Pressupondo o espaço-tempo socioambiental um co-produto do holomovimento criativo da natureza (LOIOLA, 2010, p.12), argumenta-se que objetos, ações e processos naturais inscrevem marcas materiais e imateriais, convertendo-se em expressões potenciasde memórias socioambientais. Ao interagir recursiva e retroativamente com o acontecer presente, as marcas pretéritas não o determinam, porém, orientam a materialização de possibilidades em novas realidades. Tal conversão é evidenciada aqui no uso de marcadores espaço-temporais por sociedades modernas e tradicionais, como resultante de acúmulos de saberes histórico-sociais, extraídos de regularidades celestiais, ciclos ambientais, sociais ou mitos.; This work represents the continuity of the elaboration of a complex perspective in the geography. Presupposing the space-time socio-environmental a co-product of the holomovement creative of the nature (LOIOLA, 2009: 15), it argues that objects, actions and natural processes inscribe material and immaterial  marks, converting itself in potentials expressions of memories social-environmental. As soon as interacts recursive and retroactively with the present...

The spatiotemporal constraint on the swimmer’s decision-making of turning

Oliveira,Thiago A. Costa de; Torriani-Pasin,Camila; Silva,Silvia Letícia; Denardi,Renata Alvares; Madureira,Fabrício; Apolinário,Marcos Roberto; Corrêa,Umberto Cesar
Fonte: Edições Desafio Singular Publicador: Edições Desafio Singular
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/09/2014 EN
Relevância na Pesquisa
36.75%
This study investigated the swimmer’s decision-making process for turning, based on spatiotemporal informational variables. The men and women 50-metre front crawl and backstroke events were selected and analyzed using TACTO software. Participants included 120 adults of both genders aged between 20 and 70 years. The distance to the pool wall at which the swimmers initiated the turn was analyzed with regards to velocity and variability of previous displacement. These factors were split into four groups adopting, quartiles as the cut-off points. Results showed that for all conditions, the swimmers who showed a higher velocity and a lower variability of displacement decided to initiate the turn at a greater distance to the pool wall. Furthermore, the greater distance seemed to be associated with a more successful performance. These results suggest that swimmers should be attuned to spatiotemporal and spatial information in order to maximize their performance.

Spatiotemporal analysis of lung cancer incidence and case fatality in Villa Clara province, Cuba

Batista,Norma E.; Antón,Oscar A.
Fonte: Medical Education Cooperation with Cuba Publicador: Medical Education Cooperation with Cuba
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/07/2013 EN
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INTRODUCTION: Cancer has historically been a main cause of death in Cuba, with lung cancer the number one cause of cancer death in both sexes. Cancer morbidity and mortality rates are the basic measures of cancer impact in the community. Cancer mortality has been one of the major applications of geographic analysis and has made important progress in recent decades thanks to access to mortality statistics and to development and availability of geographic information systems. Cuba does not have a strong tradition of etiologic research using spatial analysis. High levels of lung cancer morbidity and mortality in Villa Clara and growing interest in spatial analysis as an epidemiologic tool motivated this study. OBJECTIVE: To identify spatial and/or spatiotemporal clusters of lung cancer morbidity and case fatality in the province of Villa Clara, and to demonstrate the value of cluster analysis as an epidemiologic tool. METHODS: Descriptive observational study based on administrative data, using the technique of space-time scan statistics. The study focused on new cases diagnosed in 2004 and case-fatality for those cases through 2009. Variables used were: cases diagnosed, deaths, date of diagnosis, date of death, municipality and Cartesian geocoding for each municipality. RESULTS: The study identified significant spatial and spatiotemporal clusters of greater than expected lung cancer incidence (municipalities of Encrucijada...