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Acupuncture-ameliorated menopausal symptoms: single-blind, placebo-controlled, randomized trial

LUCA, A. Castelo Branco de; FONSECA, A. Maggio da; LOPES, C. M. Carvalho; BAGNOLI, V. R.; SOARES JR., J. M.; BARACAT, E. C.
Fonte: INFORMA HEALTHCARE Publicador: INFORMA HEALTHCARE
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
66.66%
Objectives To evaluate the effects of acupuncture and sham-acupuncture on women with menopausal symptoms as reflected in the intensity of their hot flushes and the Kupperman Menopausal Index (KMI). Method This was a randomized, single-blind, placebo-controlled, cross-over trial with 81 patients assigned to two groups: Group 1 received 12 months of acupuncture, then 6 months of sham-acupuncture treatment (n = 56) and Group 2 received 6 months of sham-acupuncture, then 12 months of acupuncture treatment (n = 25). The needles were inserted in a harmonic craniocaudal manner at a depth of about 2 cm, and each session lasted approximately 40 min. The efficacy of acupuncture in ameliorating the climacteric symptoms of patients in postmenopause was determined through the KMI and the intensity of hot flushes. The analysis of variance method for two factors and repeated measures was applied. Results The baseline values of the women in both groups were similar for the KMI score and number of hot flushes. At the end of 6 months, the values for the KMI and hot flushes for the women in Group 1 were lower than those of the women in Group 2 (p < 0.05). After 12 months, the KMI and hot flush data were similar in both groups. After 18 months, the values of the KMI and hot flushes for the women in Group 2 for were lower than those of the women in Group 1 (p < 0.05). Conclusion Acupuncture treatment for relieving menopausal symptoms may be effective for decreasing hot flushes and the KMI score in postmenopausal women.; FAPESP; CAPES...

The effects of cinnarizine on menopausal symptoms in women

CEZARINO, Pérsio Yvon Adri; BAGNOLI, Vicente Renato; FONSECA, A. M.; SOARES JR., J. M.; BARACAT, E. C.
Fonte: INFORMA HEALTHCARE; LONDON Publicador: INFORMA HEALTHCARE; LONDON
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
66.68%
Objective To evaluate the effectiveness and safety of cinnarizine in the treatment of menopausal symptoms. Design A total of 100 climacteric and symptomatic women participated in a double-blind, placebo-controlled study. They were divided into two groups of the same size: Gcin, intake of 25 mg of cinnarizine every 12 h for 6 months (n = 50); and Gpla, placebo intake every 12 hours for 6 months (n = 50). Menopausal symptoms were evaluated according to the Kupperman menopausal index on the first visit and at 6 months of treatment. A total of 62 women completed the study: 27 from the Gcin group and 35 from the Gpla group. Results Based on the Kupperman menopausal index, there were no statistically significant differences between the two groups before and after the treatment. Conclusion Our data suggest cinnarizine is not effective on menopausal symptoms because it had no more efficacy than placebo.; Universidade de São Paulo - Discipline of Gynecology, FMUSP

Avaliação do efeito da isoflavona sobre o epitélio cérvico-vaginal e sintomas da menopausa; Evaluation of the effect of isoflavona on the cervico-vaginal epithelium and symptoms of Menopause

Rodrigues, Edna Talarico
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 24/01/2007 PT
Relevância na Pesquisa
46.52%
A menopausa é conseqüência da falência ovariana, caracterizada pela queda na produção de estrógenos, podendo causar na mulher vários sintomas e condições patológicas como vaginite atrófica, osteoporose e doençsa cardiovasculares. A terapia estroprogestiva é largamente prescrita na pós-menopausa, no entanto existem freqüentes efeitos colaterais e contra-indicações, inclusive possibilidade de aumento do câncer de mama. Devido a toda esta polêmica as terapias alternativas para combaterem os sintomas da menopausa estão largamente sendo exploradas, neste contexto cita-se os fitohormônios. A isoflavona é um deles obtido de várias plantas e mais usualmente da soja, que possui na sua molécula uma estrutura fenólica que se liga aos receptores de estrogênio e exerce um efeito estrogênico. Neste estudo enfocando a isoflavona, extraída da soja Glycine max, para o tratamento dos sintomas da menopausa, avaliou-se o efeito desse composto sobre a maturação do epitélio cérvico-vaginal e microbiota vaginal. Para isto propô-se um estudo randomizado, duplo cego, placebo controlado do qual participaram 49 voluntárias. Um grupo de 23 mulheres recebeu 1 cápsula/dia de 40 mg de caseína de leite, constituindo o grupo placebo e o outro grupo de 26 mulheres tratadas com 1 cápsula/dia de 40 mg de isoflavona. Amostras de urina e secreção vaginal para colpocitograma...

Efeitos do Trifolium pratense nos sintomas da menopausa e na satisfação sexual em mulheres climatéricas; Effects of Trifolium pratense in menopausal symptoms and sexual satisfaction in climacteric women

Giorno, Cecilia Del
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 13/10/2009 PT
Relevância na Pesquisa
46.6%
Objetivo: avaliar os efeitos do tratamento com o Trifolium pratense nos sintomas menopausais em mulheres climatéricas utilizando o Índice Menopausal de Kupperman (IMK) e pelo Inventário de Satisfação Sexual Golombok e Rust versão feminina (GRISS) l. Metodologia: Este estudo foi prospectivo, randomizado, duplo cego e controlado com placebo, e realizado no setor de Ginecologia Endócrina e Climatério da Disciplina de Ginecologia do Departamento de Obstetrícia e Ginecologia do Hospital das Clínicas, da Faculdade de Medicina da Universidade de São Paulo. Foram selecionadas 100 mulheres na faixa etária de 45 a 65 anos com sintomas menopausais, com amenorréia superior há 1 ano e sem tratamento nos últimos 6 meses. Após a seleção, as mulheres foram divididas em dois grupos: Grupo I (n = 50) receberam Trifolium pratense na dose de 40 mg, 1 capsula/dia, por via oral; Grupo II (n = 50) receberam placebo (controle), contendo lactose, 1 cápsula/dia por via oral. A duração do tratamento foi de 12 meses e as mulheres foram avaliadas antes do tratamento com quatro, oito e 12 meses de tratamento, por exames clínico e laboratorial. Aplicaram-se o teste de t Student e o ANOVA para avaliar as diferenças entre os grupos. Resultados: Houve melhora significante dos sintomas após quatro meses de tratamento no IMK...

La última palabra en dosis mínima

Fernandes, César Eduardo; De Azevedo, Lucía Helena; Stephan, Cristina; De Souza Ferreira, José Arnaldo; De Melo, Nilson Roberto; Peixoto, Sergio
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Revisão Formato: 13-19
SPA
Relevância na Pesquisa
46.54%
In this article we rewiewed the indications of the low-dose hormone replacement therapy in post menopausal women. We evaluate the effects of this therapy on menopausal symptoms bone metabolism, cardiovascular risk and endometrial cancer. The low-dose hormone replacement therapy is satisfactory to relief menopausal symptoms and improves lipid profile preventing atherosclerosis. It does not increase the risk of hyperplasia or endometrial cancer when is associate with progestagens. The low dose hormone replacement therapy is also associate to improve bone mineral density but to have better comprehension about the effective action of the low dose hormone replacement therapy on bone, more studies evaluating the risk of fractures are necessary.

Sintomas climatéricos e fatores associados em mulheres HIV soropositivas = : Menopausal symptoms and associated factors in HIV-positive women; Menopausal symptoms and associated factors in HIV-positive women

Jeffrey Frederico Lui Filho
Fonte: Biblioteca Digital da Unicamp Publicador: Biblioteca Digital da Unicamp
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 26/04/2013 PT
Relevância na Pesquisa
46.64%
Introdução: Com o surgimento da terapia antirretroviral ocorreu significativa queda da mortalidade por doenças relacionadas ao HIV, transformando assim esta infecção em uma doença crônica. Com o envelhecimento, maior sobrevida da população infectada e, também, pelo surgimento de novos casos na faixa etária climatérica, tem havido aumento significativo na prevalência de mulheres portadoras desse vírus em idade mais avançada. Estudos atuais sugerem que estas mulheres experimentam a menopausa e o climatério de forma diferente das mulheres soronegativas, tanto pela idade mais precoce da menopausa, quanto por sintomas mais intensos. Objetivo: Em mulheres HIV soropositivas avaliar os sintomas climatéricos e fatores associados. Sujeitos e métodos: Realizou-se um estudo de corte transversal em 537 mulheres, entre 40 e 60 anos, sendo 273 HIV soropositivas e 264 soronegativas. Todas foram submetidas à entrevista para avaliação das características sociodemográficas e sintomas climatéricos. Resultados: A média etária foi 47,7±5,8 anos nas mulheres HIV soropositivas e 49,8±5,3 anos nas soronegativas (p<0,001). Análise bivariada mostrou menor prevalência de sintomas vasomotores no grupo soropositivo (p=0,009), especificamente fogachos (p<0...

Menopause and midlife: menopausal symptoms, body weight and well-being

Pimenta, Filipa
Fonte: ISPA - Instituto Universitário Publicador: ISPA - Instituto Universitário
Tipo: Tese de Doutorado
Publicado em //2011 ENG
Relevância na Pesquisa
66.79%
Dissertação apresentado ao ISPA-Instituto Universitário para obtenção do grau de Doutor em Psicologia Aplicada: Especialidade Psicologia da Saúde; A menopausa tem sido genericamente definida como um fenómeno bio-médico, tendo como consequência a emergência de sintomas físicos e psicológicos decorrentes da diminuição de estrogénios endógenos. O presente trabalho pretende alargar esta conceptualização da menopausa, contextualizando-a no modelo bio-psico-sócio-cultural, explorando se variáveis pessoais (como a espiritualidade) e contextuais (por exemplo, acontecimentos de vida) podem predizer sintomas reconhecidos como de menopausa. É ainda objectivo deste estudo explorar que variáveis estão associadas ao aumento de peso na transição para a menopausa e na pós-menopausa, e se uma intervenção breve cognitivo-comportamental pode promover a diminuição de peso em mulheres com obesidade e excesso de peso. Finalmente, pretende-se construir um modelo causal de bem-estar subjectivo na meia-idade. Uma amostra comunitária constituída por 1.003 mulheres com idades compreendidas entre os 42 e os 60 anos, recolhida maioritariamente através de estabelecimentos de ensino na área de Lisboa, preencheu um questionário para recolha de informação sócio-demográfica...

Relation between cigarette smoking and use of hormonal replacement therapy for menopausal symptoms.

Greenberg, G; Thompson, S G; Meade, T W
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /03/1987 EN
Relevância na Pesquisa
46.56%
The aim of this study was to characterise new users of hormonal replacement therapy (HRT) for the relief of menopausal symptoms and to compare these women with never-users of HRT; 402 new users and 804 never-users were studied. Hot flushes were the most common symptom in both users and non-users and were the most frequent reason for prescribing HRT. The prevalence of menopausal symptoms in non-users of HRT was high although substantially lower than that in users. HRT users were more likely to be current cigarette smokers than were never-users. There was also, within smokers, a significant relation between the number of cigarettes smoked and the likelihood of using HRT. This relation between HRT use and smoking could result from an anti-oestrogen effect of smoking, intensifying menopausal symptoms. Of potential clinical relevance is the suggestion that a proportion of women using HRT may be doing so in order to alleviate smoking-induced symptoms. Users of HRT were also more likely to have used oral contraceptives than were never-users; this relation was probably behavioural.

Measuring the impact of menopausal symptoms on quality of life.

Daly, E; Gray, A; Barlow, D; McPherson, K; Roche, M; Vessey, M
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em 02/10/1993 EN
Relevância na Pesquisa
46.68%
OBJECTIVE--To examine the impact of menopausal symptoms on the overall quality of life of women. DESIGN--Data collection with a questionnaire administered by an interviewer, incorporating two different quality of life measurement techniques (time trade off and rating scale). SETTING--Specialist menopause clinic and two general practices in Oxford. SUBJECTS--63 women aged 45-60 years recruited opportunistically during a clinic or appointment with a general practitioner; no exclusion criteria. RESULTS--Subjects gave very low quality of life ratings for health states with menopausal symptoms. The time trade off method of measuring preferences for these health states (on a scale from 0 to 1, where preference for full health is given as 1) yielded utility values of 0.64 for severe menopausal symptoms and 0.85 for mild symptoms. The rating scale measurement technique yielded even lower values: utilities of 0.30 and 0.65 were obtained for severe and mild symptoms respectively. Kappa scores indicated that the two methods produced results that were poorly related but not contradictory. Comparison of quality of life ratings before and after treatment with hormone replacement therapy showed significant improvements: with the rating scale measurement technique mean increases in utility values after the relief of severe and mild menopausal symptoms were 0.56 and 0.18 respectively. CONCLUSIONS--Quality of life may be severely compromised in women with menopausal symptoms...

Botanical and Dietary Supplements for Menopausal Symptoms: What Works, What Doesn’t

Geller, Stacie E.; Studee, Laura
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /09/2005 EN
Relevância na Pesquisa
46.67%
All women reach menopause and approximately two-thirds of women develop menopausal symptoms, primarily hot flashes. Hormone therapy long was considered the first line of treatment for vasomotor symptoms. However, given the results of the Women’s Health Initiative, many women are reluctant use exogenous hormones for symptomatic treatment and are turning to botanicals and dietary supplement (BDS) products for relief. Despite the fact that there is limited scientific evidence describing efficacy and long term safety of such products, many women find these “natural treatments” appealing. Peri- and postmenopausal women are amongst the highest users of these products, but 70% of women do not tell their health care providers about their use. Compounding this issue is the fact that few clinicians ask their patients about use of BDS, largely because they have not been exposed to alternative medical practices in their training and are unfamiliar with these products. This paper reviews the botanicals and dietary supplements commonly used in menopause...

Personality, Menopausal Symptoms, and Physical Activity Outcomes in Middle-Aged Women

Elavsky, Steriani; McAuley, Edward
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /01/2009 EN
Relevância na Pesquisa
46.59%
The menopausal transition is characterized by increased reporting of various symptoms, however, little is known about what underlies individual differences in their reporting. The present study examined the contribution of personality factors to the reporting of menopausal symptoms in the context of a 4-month randomized controlled exercise trial. Symptomatic middle-aged women (N = 164 M age = 49.9, SD = 3.6) completed measures of menopausal symptoms, personality, physical activity, fitness and body composition assessment at the beginning and end of a 4-month randomized controlled trial involving walking and yoga. After controlling for baseline values, psychological symptoms at the end of the trial were associated with trait anxiety (β = .47, p < .001) and changes in fitness (β = -.20, p < .01); vasomotor symptoms with optimism (β = -.18, p < .05) and changes in fitness (β = -.15, p = .053); and sexual symptoms were associated with changes in fitness (β = -.16, p < .05). Personality characteristics partially explain symptom reports during menopause however improvements in physical parameters such as fitness may reduce reported symptomatology.

Short-Term Exercise Approaches on Menopausal Symptoms, Psychological Health, and Quality of Life in Postmenopausal Women

Ağıl, Ayşegül; Abıke, Faruk; Daşkapan, Arzu; Alaca, Rıdvan; Tüzün, Handan
Fonte: Hindawi Publishing Corporation Publicador: Hindawi Publishing Corporation
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
46.6%
Objective. This study was designed to determine the effects of different short-term exercise programs on menopausal symptoms, psychological health, and quality of life in postmenopausal women. Material and Methods. Forty-two women were chosen from volunteering postmenopausal women presenting to the Department of Obstetrics and Gynecology of Bayındır Hospital between March and December 2009. The women aged 45–60 years and experiencing menopause naturally were included in the study. They were randomly divided into aerobic (n = 18) and resistance (n = 18) exercise groups. The women exercised 3 days per week for 8 weeks under the supervision of a physiotherapist. Aerobic exercise training was performed through a bicycle ergometer. Before and after the training, lipid profiles were measured and menopausal symptoms, psychological health, depression, and the quality of life were assessed through questionnaires. Results. In both exercise groups, no significant changes in lipid profiles were observed. In the resistance exercise group, excluding the urogenital complaints, there were significant improvements in all subscales of Menopausal Rating Scale (MRS). In the resistance exercise group, excluding the phobic anxiety, there were significant improvements in all subscales of The Symptom Checklist. Depression levels significantly decreased in both groups. Improvements were observed in all subscales of menopause-specific quality of life questionnaire in both groups except for sexual symptoms. Conclusion. Resistance exercise and aerobic exercise were found to have a positive impact on menopausal symptoms...

Effectiveness of Yoga for Menopausal Symptoms: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Cramer, Holger; Lauche, Romy; Langhorst, Jost; Dobos, Gustav
Fonte: Hindawi Publishing Corporation Publicador: Hindawi Publishing Corporation
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
46.68%
Objectives. To systematically review and meta-analyze the effectiveness of yoga for menopausal symptoms. Methods. Medline, Scopus, the Cochrane Library, and PsycINFO were screened through April 2012. Randomized controlled trials (RCTs) were included if they assessed the effect of yoga on major menopausal symptoms, namely, (1) psychological symptoms, (2) somatic symptoms, (3) vasomotor symptoms, and/or (4) urogenital symptoms. For each outcome, standardized mean differences (SMDs) and 95% confidence intervals (CIs) were calculated. Two authors independently assessed risk of bias using the risk of bias tool recommended by the Cochrane Back Review Group. Results. Five RCTs with 582 participants were included in the qualitative review, and 4 RCTs with 545 participants were included in the meta-analysis. There was moderate evidence for short-term effects on psychological symptoms (SMD = −0.37; 95% CI −0.67 to −0.07; P = 0.02). No evidence was found for total menopausal symptoms, somatic symptoms, vasomotor symptoms, or urogenital symptoms. Yoga was not associated with serious adverse events. Conclusion. This systematic review found moderate evidence for short-term effectiveness of yoga for psychological symptoms in menopausal women. While more rigorous research is needed to underpin these results...

Efficacy and Side Effects of Chinese Herbal Medicine for Menopausal Symptoms: A Critical Review

Xu, Lian-Wei; Jia, Man; Salchow, Roland; Kentsch, Michael; Cui, Xue-Jun; Deng, Hong-Yong; Sun, Zhuo-Jun; Kluwe, Lan
Fonte: Hindawi Publishing Corporation Publicador: Hindawi Publishing Corporation
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
46.49%
This study evaluates 23 (9 Chinese and 14 non-Chinese) randomized controlled trials for efficacy and side effects of Chinese herbal medicine on menopausal symptoms. Menopause was diagnosed according to western medicine criteria in all studies while seven Chinese studies and one non-Chinese study further stratified the participants using traditional Chinese medical diagnosis “Zheng differentiation.” Efficacy was reported by all 9 Chinese and 9/14 non-Chinese papers. Side effects and adverse events were generally mild and infrequent. Only ten severe adverse events were reported, two with possible association with the therapy. CHM did not increase the endometrial thickness, a common side effect of hormone therapy. None of the studies investigated long-term side effects. Critical analysis revealed that (1) high-quality studies on efficacy of Chinese herbal medicine for menopausal syndrome are rare and have the drawback of lacking traditional Chinese medicine diagnosis (Zheng-differentiation). (2) Chinese herbal medicine may be effective for at least some menopausal symptoms while side effects are likely less than hormone therapy. (3) All these findings need to be confirmed in further well-designed comprehensive studies meeting the standard of evidence-based medicine and including Zheng-differentiation of traditional Chinese medicine.

Menopausal Symptoms among Breast Cancer Patients: A Potential Indicator of Favorable Prognosis

Chen, Yong; Dorjgochoo, Tsogzolmaa; Bao, Ping-Ping; Zheng, Ying; Cai, Hui; Lu, Wei; Shu, Xiao-Ou
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
Publicado em 30/09/2013 EN
Relevância na Pesquisa
46.73%
Menopausal symptoms have been suggested to be an indicator of better prognosis among patients treated for breast cancer, because women who experience these symptoms usually have a lower level of estrogen. We tested this hypothesis in a population-based, prospective cohort study involving 4,842 women with stage 0 to III primary breast cancer who were enrolled in the Shanghai Breast Cancer Survival Study between March 2002 and April 2006, were aged 20 to 75 years, and were recruited 6 months post-diagnosis. They were followed-up by in-person surveys and record linkages with the vital statistics registry. Cox regression analysis was used to evaluate the association of menopausal symptoms at baseline with breast cancer recurrence. Approximately 56% of patients experienced at least one menopausal symptom, including hot flashes, night sweats, and/or vaginal dryness at baseline. During a median follow-up period of 5.3 years, 720 women had a recurrence. Experiencing hot flashes or having ≥2 menopausal symptoms was associated with lower risk of recurrence among premenopausal women (hazard ratio [HR]=0.77, 95% confidence interval [CI]: 0.62-0.96 for hot flashes; 0.73, 0.56-0.96 for ≥2 menopausal symptoms). Lower recurrence risk in relation to hot flashes was also observed among women who were not overweight/obese (HR=0.78...

A hidden reason for menopausal symptoms in premenopausal aged women: depression

Cekmez, Yasemin; Torun, Fuat; Göçmen, Ahmet; Şanlıkan, Fatih
Fonte: e-Century Publishing Corporation Publicador: e-Century Publishing Corporation
Tipo: Artigo de Revista Científica
Publicado em 15/04/2015 EN
Relevância na Pesquisa
46.72%
Background: The relationship between depression and reproductive hormone changes in menopausal women is well konown but recent animal studies showed that depression can also cause changes in reproductive hormone levels. According to this, we aimed to eveluate the impact of depression on circulating follicle-stimulating hormone and estradiol levels in premenopausal women in terms of menopausal symptoms. Material-method: A total of 120 premenoupausal women (age ranges 41-45) were divided into two groups as: study group consisted of patients (n = 60) with depression and the control group (n = 60) involved healthy women. Psychometric assessment of study group was done by the Turkish version of Structured Clinical Interview for DSM-IV Diagnosis.The presence of menopausal symptoms of all subjects was assessed by the Turkish version of Menopause Rating Scale and hormonal activity by estimating estradiol and follicle-stimulating hormone levels. Results: Study group had significantly lower mean concentration of estradiol and higher intensity of menopausal symptoms than control group. Presence and severity of menopausal symptoms were not associated with follicle-stimulating hormone concentrations. Conclusion: The results of this study confirm the connection between menopausal symptoms and depression both on clinical and physiological level.The current study is unique in its ability to assess the effects of depression on menopausal symptoms in women as they are still reproductive.

Bee pollen and honey for the alleviation of hot flushes and other menopausal symptoms in breast cancer patients

MÜNSTEDT, KARSTEN; VOSS, BENJAMIN; KULLMER, UWE; SCHNEIDER, URSULA; HÜBNER, JUTTA
Fonte: D.A. Spandidos Publicador: D.A. Spandidos
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
46.53%
Hot flushes, night sweats, pain during sexual intercourse, hair loss, forgetfulness, depression and sleeping disturbances are common problems among breast cancer patients undergoing antihormonal treatment. The aim of this study was to investigate whether bee pollen can alleviate menopausal symptoms in patients receiving tamoxifen and aromatase inhibitors/inactivators. We compared a pollen-honey mixture with pure honey (placebo) in a prospective, randomized crossover trial in breast cancer patients receiving antihormonal treatment. The menopausal complaints were assessed using the Menopause Rating Scale (MRS). A total of 46 patients were recruited; 68.3% (28/41) of the patients reported an improvement in their symptoms while taking honey, compared with 70.9% (22/31) who reported an improvement with pollen (the difference was non-significant). The results were confirmed by significant improvements in the postmenopausal complaints in the two groups in a pre-post analysis in the MRS and its 3 subscales. This study provided evidence that honey and bee pollen may improve the menopausal symptoms of breast cancer patients on antihormonal treatment. Of note, honey, which was intended to be used as a placebo, produced similar effects as pollen and they both exceeded the extent of a placebo effect in this setting (~25%).

Black cohosh (Cimicifuga spp.) for menopausal symptoms

Leach, M.; Moore, V.
Fonte: Update Software Ltd Publicador: Update Software Ltd
Tipo: Artigo de Revista Científica
Publicado em //2012 EN
Relevância na Pesquisa
46.71%
BACKGROUND Menopause can be a distressing and disruptive time for many women, with many experiencing hot flushes, night sweats, vaginal atrophy and dryness. Postmenopausal women are also at increased risk of osteoporosis. Interventions that decrease the severity and frequency of these menopausal symptoms are likely to improve a woman's well-being and quality of life. Hormone therapy has been shown to be effective in controlling the symptoms of menopause; however, many potentially serious adverse effects have been associated with this treatment. Evidence from experimental studies suggests that black cohosh may be a biologically plausible alternative treatment for menopause; even so, findings from studies investigating the clinical effectiveness of black cohosh have, to date, been inconsistent. OBJECTIVES To evaluate the clinical effectiveness and safety of black cohosh (Cimicifuga racemosa or Actaea racemosa) for treating menopausal symptoms in perimenopausal and postmenopausal women. SEARCH METHODS Relevant studies were identified through AARP Ageline, AMED, AMI, BioMed Central gateway, CAM on PubMed, CINAHL, CENTRAL, EMBASE, Health Source Nursing/Academic edition, International Pharmaceutical Abstracts, MEDLINE, Natural medicines comprehensive database...

Aromatherapy Massage Affects Menopausal Symptoms in Korean Climacteric Women: A Pilot-Controlled Clinical Trial

Hur, Myung-Haeng; Yang, Yun Seok; Lee, Myeong Soo
Fonte: Oxford University Press Publicador: Oxford University Press
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
46.54%
This study investigated the effects of aromatherapy massage on menopausal symptoms in Korean climacteric women. Kupperman's menopausal index was used to compare an experimental group of 25 climacteric women with a wait-listed control group of 27 climacteric women. Aromatherapy was applied topically to subjects in the experimental group in the form of massage on the abdomen, back and arms using lavender, rose geranium, rose and jasmine in almond and primrose oils once a week for 8 weeks (eight times in total). The experimental group reported a significantly lower total menopausal index than wait-listed controls (P < 0.05). There were also significant intergroup differences in subcategories such as vasomotor, melancholia, arthralgia and myalgia (all P < 0.05). These findings suggest that aromatherapy massage may be an effective treatment of menopausal symptoms such as hot flushes, depression and pain in climacteric women. However, it could not be verified whether the positive effects were from the aromatherapy, the massage or both. Further rigorous studies should be done with more objective measures.

Increased menopausal symptoms among Afro-Colombian women as assessed with the Menopause Rating Scale

Blumel, Juan E.; Chedraui, Peter; Monterrosa Castro, Alvaro
Fonte: ELSEVIER Publicador: ELSEVIER
Tipo: Artículo de revista
EN
Relevância na Pesquisa
46.62%
Background: Increased frequency and severity of menopausal symptoms have been associated to black race. However, this situation has not been described in any Latin American population. Objective: Compare frequency and severity of menopausal symptoms among Afro and non-Afro Hispanic Colombian climacteric women. Methods: In this cross-sectional study, healthy Afro and non-Afro-Colombian women aged 40-59 years were asked to fill out the Menopause Rating Scale (MRS) questionnaire in order to compare symptom frequency and intensity. Results: A total of 578 women were surveyed (201 Afro-Colombian and 377 non-Afro-Colombian). Mean age of the whole sample was 47.9 +/- 5.9 years (median 47), with no differences among studied groups in terms of age, parity, and hormone therapy (HT) use. Intensity of menopausal symptoms, assessed with the total MRS score, was found to be significantly higher among Afro-Colombian women (10.6 +/- 6.7 vs. 7.5 +/- 5.7, p = 0.0001), which was due to higher somatic and psychological subscale scores. In this group, the frequency of somatic symptoms, heart discomfort and muscle and joint problems, was found to be higher than in non-Afro-Colombian women (38.8% vs. 26.8% and 77.1% vs. 43.5%, respectively, p < 0.05); equally...