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Resultados filtrados por Publicador: Universidade de São Paulo (USP), Conjunto Quimicas

Assessment of pharmacotherapeutic safety of medical prescriptions for elderly residents in a long-term care facility

Varallo, Fabiana Rossi; Stein Ambiel, Ingrid Stephanie; Nanci, Luana Orlandelli; Fernandes Galduroz, Jose Carlos; Mastroianni, Patricia de Carvalho
Fonte: Universidade de São Paulo (USP), Conjunto Quimicas Publicador: Universidade de São Paulo (USP), Conjunto Quimicas
Tipo: Artigo de Revista Científica Formato: 477-485
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The present study aimed to estimate the prevalence of elderly using potentially inappropriate medications (PIM) and with occurrence of potentially hazardous drug interactions (PHDI), to identify the risk factors for the prescription of PIM and to evaluate the impact of pharmaceutical intervention (PI) for the prescription of safer therapeutic alternatives. Therefore, a cross-sectional study was performed in a long-term care facility in São Paulo State, between December/2010 and January/2011. The medical records of the patients >= 60 years old who took any drugs were consulted to assess the pharmacotherapeutic safety of the medical prescriptions, in order to identify PIM and PHDI, according to the Beers (2003) and World Health Organization criteria, respectively. PI consisted of a guidance letter to the physician responsible for the institution, with the suggestions of safer equivalent therapeutics. Approximately 88% of the elderly took at least one drug, and for 30% of them the PIM had been prescribed. Most of the PIM identified (53.4%) act on the central nervous system. Among the 13 different DI detected, 6 are considered PHDI. Polypharmacy was detected as a risk factor for PIM prescription. After the PI there was no change in medical prescriptions of patients who had been prescribed PIM or PHDI. The data suggests that PI performed by letter...