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Adaptive immunity is related to coronary artery disease severity after acute coronary syndrome in subjects with metabolic syndrome

Izar, Maria Cristina de Oliveira; Fonseca, Henrique A.; Pinheiro, Luiz F.; Monteiro, Carlos M.; Póvoa, Rui M.; Monteiro, Andrea Moreira; Figueiredo Neto, Antonio Martins; Gidlund, Magnus Ake; Fonseca, Francisco A.
Fonte: Sherborne Gibbs; Londres Publicador: Sherborne Gibbs; Londres
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
27.28%
Metabolic syndrome (MetS) is an inflammatory state associated with high coronary disease risk. Inflammation and adaptive immunity modulate atherosclerosis and plaque instability. We examined early changes in anti-oxidized lowdensity lipoprotein (LDL) (anti-oxLDL) autoantibodies (Abs) in patients with MetS after an acute coronary syndrome (ACS). Patients of both genders (n=116) with MetS were prospectively included after an acute yocardial infarction (MI) or hospitalization due to unstable angina. Anti-oxLDL Abs (IgG class) were assayed at baseline, three and six weeks after ACS. The severity of coronary disease was evaluated by the Gensini score. We observed a decrease in anti-oxLDL Abs titers (p<0.002 vs. baseline), mainly in males (p=0.01), in those under 65 y (p=0.03), and in subjects with Gensini score above median (p=0.04). In conclusion, early decrease in circulating anti-oxLDL Abs is associated with coronary disease severity among subjects with MetS.; FAPESP - 2004/00325-8; CNPq-INCT-FCx; INCT-INAMI

Metabolismo dos quilomícrons e capacidade da lipoproteína de alta densidade (HDL) de receber lípides na síndrome metabólica e no diabetes mellitus tipo 2; Chylomicron metabolism and lipid reception capacity of high density lipoprotein in metabolic syndrome (MetS) and type 2 diabetes mellitus (DM2)

Silva, Vanessa Monteiro da
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 30/01/2008 PT
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O principal distúrbio metabólico decorrente do Diabetes mellitus tipo 2 e da Síndrome Metabólica corresponde a alterações no metabolismo lipídico. Portanto, torna-se importante a melhor compreensão de alguns aspectos do metabolismo de lipoproteínas plasmáticas. Nesse sentido, a avaliação do metabolismo dos quilomícrons e da transferência de lípides de lipoproteínas plasmáticas para a lipoproteína de alta densidade (HDL), pode fornecer informações importantes relacionadas com o processo aterogênico. No presente estudo, foram estudados 15 indivíduos portadores de Diabetes mellitus tipo 2, 15 indivíduos com Síndrome Metabólica e 14 controles normolipidêmicos. Foi avaliada a cinética plasmática de uma nanoemulsão lipídica artificial com comportamento metabólico similar ao dos quilomícrons naturais, marcada com triglicérides (TG-3H) e éster de colesterol (EC-14C) radioativos. A nanoemulsão de quilomícrons artificiais foi injetada endovenosamente e amostras de sangue foram coletadas durante intervalos préestabelecidos. As curvas de decaimento plasmático dos lípides radioativos da nanoemulsão foram traçadas e as taxas fracionais de remoção (TFR) foram calculadas por análise compartimental. Para avaliação da transferência de lípides foi utilizada uma nanoemulsão semelhante a LDL (LDE) marcada com TG-3H e colesterol livre-14C (CL-14C) ou fosfolípides-14C (PL-14C) e EC-3H...

RODA : an open-source digital repository designed for preservation

Ferreira, Miguel
Fonte: Universidade do Minho Publicador: Universidade do Minho
Tipo: Conferência ou Objeto de Conferência
Publicado em 19/11/2013 ENG
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Apresentação efetuada no Preserving and Archiving Electronically Generated Materials, The Morgan Library & Museum, NY, 2013; RODA, an open-source digital repository designed for preservation RODA is a digital repository that delivers functionality for all the main units of the OAIS reference model. RODA is capable of ingesting, managing and providing access to the various types of digital content produced by large corporations or public bodies. Based on open-source technologies, it is supported by existing standards such as the OAIS, METS, EAD and PREMIS. In this presentation we will provide a brief look at the functionality currently; KEEP SOLUTIONS

The prevalence of the metabolic syndrome increases through the quartiles of thyroid stimulating hormone in a population-based sample of euthyroid subjects

Shinkov,Alexander; Borissova,Anna-Maria; Kovatcheva,Roussanka; Atanassova,Iliana; Vlahov,Jordan; Dakovska,Lilia
Fonte: Sociedade Brasileira de Endocrinologia e Metabologia Publicador: Sociedade Brasileira de Endocrinologia e Metabologia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2014 EN
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Objective The aim of the study was to assess the prevalence and characteristics of metabolic syndrome (MetS) and its elements in relation to TSH in euthyroid subjects. Materials and methods In the cross-sectional study, 2,153 euthyroid adults, 47.2 ± 14.5 years (20-94) with no current antithyroid or thyroid replacement therapy were enrolled. All participants filled a questionnaire on past and current morbidities, medication and smoking. Body weight, height, waist circumference, serum TSH, glucose and lipids were measured. The subjects were stratified by quartiles of TSH (QTSH) and the prevalence of the MetS elements was calculated. MetS was determined by the IDF 2005 criteria. Results Overweight prevalence was 37.2% (35.2-39.2), obesity in 25.1% (23.3-26.9), abdominal obesity – 61.4% (59.3-63.5), hypertension – 42.1% (38.9-43.1), diabetes/increased fasting glucose – 13.6% (12.1-15), low HDL-cholesterol – 27.6% (25.7-29.5), hypertriglyceridemia – 24.1% (22.3-25.9), MetS – 32.2% (30.2-34.2). MetS was more prevalent in the highest QTSH (34.9%...

Evaluation of the metS and murB Loci for Antibiotic Discovery Using Targeted Antisense RNA Expression Analysis in Bacillus anthracis▿

Kedar, G. C.; Brown-Driver, Vickie; Reyes, Daniel R.; Hilgers, Mark T.; Stidham, Mark A.; Shaw, Karen Joy; Finn, John; Haselbeck, Robert J.
Fonte: American Society for Microbiology (ASM) Publicador: American Society for Microbiology (ASM)
Tipo: Artigo de Revista Científica
EN
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The biowarfare-relevant bacterial pathogen Bacillus anthracis contains two paralogs each of the metS and murB genes, which encode the important antibiotic target functions methionyl-tRNA synthetase and UDP-N-acetylenolpyruvoylglucosamine reductase, respectively. Empirical screens were conducted to detect and characterize gene fragments of each of these four genes that could cause growth reduction of B. anthracis when inducibly expressed from a plasmid-borne promoter. Numerous such gene fragments that were overwhelmingly in the antisense orientation were identified for the metS1 and murB2 alleles, while no such orientation bias was seen for the metS2 and murB1 alleles. Gene replacement mutagenesis was used to confirm the essentiality of the metS1 and murB2 alleles, and the nonessentiality of the metS2 and murB1 alleles, for vegetative growth. Induced transcription of RNA from metS1 and murB2 antisense-oriented gene fragments resulted in specific reduction of mRNA of their cognate genes. Attenuation of MetS1 enzyme expression hypersensitized B. anthracis cells to a MetS-specific antimicrobial compound but not to other antibiotics that affect cell wall assembly, fatty acid biosynthesis, protein translation, or DNA replication. Antisense-dependent reduction of MurB2 enzyme expression caused hypersensitivity to beta-lactam antibiotics...

Japanese study to organize proper lifestyle modifications for metabolic syndrome (J-STOP-MetS): Design and method

Munakata, Masanori; Honma, Hiroki; Akasi, Mitugu; Araki, Takaharu; Kawamura, Takahiko; Kubota, Masashi; Yokokawa, Tomoko; Maruhashi, Akira; Toyonaga, Toshihiro;
Fonte: Dove Medical Press Publicador: Dove Medical Press
Tipo: Artigo de Revista Científica
EN
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Prevalence of the metabolic syndrome is now a very serious health problem in Japan and a public preventive strategy is essential to reduce morbidity. A systematic interventional strategy for the metabolic syndrome remains to be established. In order to address this issue, a multi-center study; Japanese Study to Organize Proper lifestyle modification for the metabolic syndrome (J-STOP-MetS), has been established by nine preventive medical centers among Rosai hospital groups. This study comprises a cross-sectional study (J-STOP-MetS 1) and a prospective randomized control study (J-STOP-MetS 2). J-STOP-MetS 1 examines the causes of the metabolic syndrome by means of a questionnaire in a large cohort of patients with the metabolic syndrome and control subjects matched for age and sex. J-STOP-MetS 2 examines the hypothesis that guidance on lifestyle modifications will help at risk patients to reduce abdominal fat and cardiovascular risk factors. The metabolic syndrome patients are randomly assigned either to a single visit to a guidance group or multiple visits every two months. The individualized guidance is provided by the coordination of physician, trained nurse, dietician and exercise trainer. Several parameters are measured before and six months after the first guidance session...

Evaluation of artificial neural network algorithms for predicting METs and activity type from accelerometer data: validation on an independent sample

Freedson, Patty S.; Lyden, Kate; Kozey-Keadle, Sarah; Staudenmayer, John
Fonte: American Physiological Society Publicador: American Physiological Society
Tipo: Artigo de Revista Científica
EN
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Previous work from our laboratory provided a “proof of concept” for use of artificial neural networks (nnets) to estimate metabolic equivalents (METs) and identify activity type from accelerometer data (Staudenmayer J, Pober D, Crouter S, Bassett D, Freedson P, J Appl Physiol 107: 1330–1307, 2009). The purpose of this study was to develop new nnets based on a larger, more diverse, training data set and apply these nnet prediction models to an independent sample to evaluate the robustness and flexibility of this machine-learning modeling technique. The nnet training data set (University of Massachusetts) included 277 participants who each completed 11 activities. The independent validation sample (n = 65) (University of Tennessee) completed one of three activity routines. Criterion measures were 1) measured METs assessed using open-circuit indirect calorimetry; and 2) observed activity to identify activity type. The nnet input variables included five accelerometer count distribution features and the lag-1 autocorrelation. The bias and root mean square errors for the nnet MET trained on University of Massachusetts and applied to University of Tennessee were +0.32 and 1.90 METs, respectively. Seventy-seven percent of the activities were correctly classified as sedentary/light...

QTL-based association analyses reveal novel genes influencing pleiotropy of Metabolic Syndrome (MetS)

Zhang, Y.; Kent, J. W.; Olivier, M.; Ali, O.; Broeckel, U.; Abdou, R. M.; Dyer, T. D.; Comuzzie, A.; Curran, J. E.; Carless, M. A.; Rainwater, D. L.; Göring, H. H. H.; Blangero, J.; Kissebah, A. H.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
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Metabolic Syndrome (MetS) is a phenotype cluster predisposing to type 2 diabetes and cardiovascular diseases. In extended families of Northern European ancestry, we previously identified two significant QTLs 3q27 and 17p12 that were linked with multiple representative traits of MetS. To determine the genetic basis of these linkage signals, QTL-specific genomic and transcriptomic analyses were performed in 1,137 individuals from 85 extended families that contributed to the original linkage. We tested in SOLAR association of MetS phenotypes with QTL-specific haplotype-tagging SNPs as well as transcriptional profiles of peripheral blood mononuclear cells (PBMCs). SNPs significantly associated with phenotypes under the prior hypothesis of linkage mapped to seven genes at 3q27 and seven at 17p12. Prioritization based on biologic relevance, SNP association, and expression analyses identified two genes: insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) at 3q27 and tumor necrosis factor receptor 13B (TNFRSF13B) at 17p12. Prioritized genes could influence cell-cell adhesion and adipocyte differentiation, insulin/glucose responsiveness, cytokine effectiveness and plasma lipids and lipoprotein densities. In summary, our results combine genomic...

Project Report W2 Conferences Workflow

Browne, Gary
Fonte: Australian Partnership for Sustainable Repositories Publicador: Australian Partnership for Sustainable Repositories
Tipo: Working/Technical Paper
EN
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To develop and demonstrate scholarly communication workflows integrating the OCS (Open Conference System) publication system with open repository platforms to provide archiving, OAIS compliant access, and online (or print hybrid) outputs that have capability of complying with recognized DEST research publication criteria. To implement this using the NLA METS profile and the APSR RIFF environment.; This report outlines the development of scholarly communication workflows integrating the OCS (Open Conference System) publication system with open repository platforms to provide archiving, OAIS compliant access, and online (or print hybrid) outputs that have capability of complying with recognized DEST research publication criteria. This has been implemented using the NLA METS profile and the APSR RIFF environment. Those involved in the Project included: Scott Yeadon and Leo Monus (Australian National University), Ross Coleman, Joshua Fry and Gary Browne (University of Sydney) and Bronwyn Lee and Megan Williams (National Library of Australia).

Report of the METS Profile Development Project

Pearce, Judith; Pearson, David; Williams, Megan; Yeadon, Scott
Fonte: Australian Partnership for Sustainable Repositories Publicador: Australian Partnership for Sustainable Repositories
Tipo: Working/Technical Paper
EN
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This document reports on the outcome of the APSR METS Profile Development Project. The APSR METS profile project aimed to develop: • an open, extensible and standard way of packaging metadata for digital objects which could be relevant to both Australian and broader contexts; and • a generic, repository independent metadata submission and exchange profile for use among APSR repositories. The basis for this project was the draft METS exchange profile developed by the NLA as part of the 2006 APSR-funded PRESTA project. The project undertook to test this profile against actual implementations and then to register it with the Library of Congress.; This reports on the outcome of the APSR METS Profile Development Project which aimed to develop an open, extensible and standard way of packaging metadata for digital objects which could be relevant to both Australian and broader contexts and a generic, repository-independent metadata submission and exchange profile for use among APSR repositories. The basis for this project was the draft METS exchange profile developed by the National Library of Australia as part of the 2006 APSR-funded PRESTA project. The project undertook to test this profile against actual implementations and then to register it with the Library of Congress.

Australian METS Profile: metadata about a journey

Pearce, Judith; Pearson, David
Fonte: Universidade Nacional da Austrália Publicador: Universidade Nacional da Austrália
Tipo: Conferência ou Objeto de Conferência
EN
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Be surprised by how interesting METS, MODS, PREMIS, MIX, DIPs and SIPs can be. Listen to David Pearson and Judith Pearce talking about their journey through this forest of acronyms to an Australian METS Profile as part of the APSR Repository Interoperability Framework (RIFF) project. "How does this relate to me?" you may ask. If you are part of the Australian data commons, you will need to know about these standards and how they work together to ensure interoperability in the Australian repository environment.; talk given by Judith Pearce and David Pearson of the National Library of Australia at the Australian National University on December 5, 2007

Measurement and prediction of METs during household activities in 35- to 45-year-old females

Brooks, A.; Withers, R.; Gore, C.; Vogler, A.; Plummer, J.; Cormack, J.
Fonte: Springer Publicador: Springer
Tipo: Artigo de Revista Científica
Publicado em //2004 EN
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This study determined whether four self-paced household tasks, conducted in the subjects homes and a standardised laboratory environment, were performed at a moderate intensity [3–6 metabolic equivalents (METs)] in a representative sample of thirty-six 35- to 45-year-old females. Energy expenditure was also predicted via indirect methods. Self-paced energy expenditure during sweeping, window cleaning, vacuuming and mowing was measured using the Douglas bag technique. Heart rate, respiratory frequency, Computer Science Applications (CSA) movement counts (hip and wrist), Borg rating of perceived exertion and Quetelets index were also recorded as potential predictors of energy expenditure. While the four activities were performed at mean intensities 3.0 METs in both the home and laboratory, all comparisons between these two environments were statistically significant (P<0.001). The 95% confidence intervals (CIs) for the home and laboratory prediction equations were ±1.1 METs and ±1.0 MET, respectively. These data suggest that the aforementioned household chores can contribute to the 30 min·day–1 of moderate-intensity activity required to confer health benefits. However, the substantial between-subject variability in energy expenditure resulted in some persons performing these tasks at a light intensity (<3.0 METs). The significant MET differences between the home and laboratory emphasise the effects of environment and terrain and the mental approach to a task on self-paced energy expenditure. Considering the means for the five activities ranged from 3.1 METs to 6.0 METs...

Predicting walking METs and energy expenditure from speed or accelerometry

Brooks, A.; Gunn, S.; Withers, R.; Gore, C.; Plummer, J.
Fonte: Lippincott Williams & Wilkins Publicador: Lippincott Williams & Wilkins
Tipo: Artigo de Revista Científica
Publicado em //2005 EN
Relevância na Pesquisa
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PURPOSE: a) Compare the predictive potential of speed and CSA(hip) (Computer Science Applications accelerometer positioned on the hip) for level terrain walking METs (1 MET = VO2 of 3.5 mL.kg(-1).min(-1)) and energy expenditure (kcal.min(-1)); b) cross-validate previously published CSA(hip)- and speed-based MET and energy expenditure prediction equations; c) measure self-paced walking speed, exercise intensity (METs) and energy expenditure in the middle aged population. METHODS: Seventy-two 35- to 45-yr-old volunteers walked around a level, paved quadrangle at what they perceived to be a moderate pace. Oxygen consumption was measured using the criterion Douglas bag technique. Speed, CSA(hip), heart rate, and Borg rating of perceived exertion were also monitored. RESULTS: Speed explained 10% more variance of walking METs than CSA(hip). Speed and mass explained 8% more variance of walking energy expenditure (kcal.min) than CSA(hip) and mass. The best previously published regression equations predict our walking METs and energy expenditures within 95% prediction limits of +/- 0.7 METs and +/- 1.0 kcal.min(-1), respectively. Women paced themselves at a significantly higher mean speed (5.5 km.h(-1)) and intensity (4.1 METs) than their male counterparts (5.2 km.h(-1) and 3.8 METs). Both genders expended approximately 0.75 kcal.kg(-1) for every kilometer of level terrain walked. CONCLUSION: Speed-based MET and energy expenditure predictions during level terrain walking were more accurate than those utilizing CSA(hip).; http://www.ncbi.nlm.nih.gov/pubmed/16015141; Brooks...

Genetic variation at the CYP2C19 gene associated with metabolic syndrome susceptibility in a South Portuguese population: results from the pilot study of the European Health Examination Survey in Portugal

Gaio, Vania; Nunes, Baltazar; Fernandes, Aida; Mendonça, Francisco; Horta Correia, Filomena; Beleza, Álvaro; Gil, Ana Paula; Bourbon, Mafalda; Vicente, Astrid; Matias Dias, Carlos; Barreto da Silva, Marta
Fonte: BioMed Central/ Brazilian Diabetes Society (SBD) Publicador: BioMed Central/ Brazilian Diabetes Society (SBD)
Tipo: Artigo de Revista Científica
Publicado em /02/2014 ENG
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BACKGROUND: Metabolic syndrome (MetS) is a cluster of conditions that occur together, increasing the risk of heart disease, stroke and diabetes. Since pathways implicated in different diseases reveal surprising insights into shared genetic bases underlying apparently unrelated traits, we hypothesize that there are common genetic components involved in the clustering of MetS traits. With the aim of identifying these common genetic components, we have performed a genetic association study by integrating MetS traits in a continuous MetS score. METHODS: A cross-sectional study developed in the context of the Portuguese Component of the European Health Examination Survey (EHES) was used. Data was collected through a detailed questionnaire and physical examination. Blood samples were collected and biochemical analyses were performed. Waist circumference, blood pressure, glucose, triglycerides and high density lipoprotein cholesterol (HDL) levels were used to compute a continuous MetS score, obtained by Principal Component Analysis. A total of 37 single nucleotide polymorphisms (SNPs) were genotyped and individually tested for association with the score, adjusting for confounding variables. RESULTS: A total of 206 individuals were studied. Calculated MetS score increased progressively with increasing number of risk factors (P < 0.001). We found a significant association between CYP2C19 rs4244285 and the MetS score not detected using the MetS dichotomic approach. Individuals with the A allelic variant seem to be protected against MetS...

Genetic variation at the CY2C19 gene associated with Metabolic Syndrome susceptibility in a South Portuguese population

Gaio, Vania; Nunes, Baltazar; Fernandes, Aida; Mendonça, Francisco; Horta Correia, Filomena; Beleza, Álvaro; Gil, Ana Paula; Bourbon, Mafalda; Vicente, Astrid; Matias Dias, Carlos; Barreto da Silva, Marta
Fonte: Instituto Nacional de Saúde Doutor Ricardo Jorge, IP Publicador: Instituto Nacional de Saúde Doutor Ricardo Jorge, IP
Tipo: Conferência ou Objeto de Conferência
Publicado em /10/2013 ENG
Relevância na Pesquisa
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Metabolic syndrome (MetS) is a cluster of conditions — increased blood pressure, high blood glucose level, excess body fat around the waist and abnormal cholesterol levels — that occur together, increasing the risk of heart disease, stroke and diabetes. In Portugal, the MetS prevalence is estimated to be 27,5% with regional variations, being highest in the Alentejo (30,99%) and lowest in the Algarve (24,42%), constituting a public health problem. Although for clinical settings, a binary definition of MetS enabling a yes or no diagnosis is useful, it is clear that dichotomizing a continuous outcome variable reduces the statistical power of the MetS association studies. Therefore, the aim of the present study is to identify genetic risk factors involved in MetS etiology, using a continuous MetS score. To achieve our goal, a principal component analysis was performed to compute a score using the six normalized risk factors for MetS (waist circumference, diastolic and systolic blood pressure, glucose, triglycerides and HDL blood levels), with a higher MetS score indicating a less favorable MetS profile. After calculating this score, an association study was performed using 37 SNPs in candidate genes involved in MetS related diseases. A total of 206 subjects...

The Australian METS Profile – A Journey about Metadata

Pearce, Judith; Pearson, David; Williams, Megan; Yeadon, Scott
Fonte: D-Lib Magazine Publicador: D-Lib Magazine
Tipo: Artigo de Revista Científica
EN
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In any journey, there's a destination but half the 'fun' is getting there. This article chronicles our journey towards a common way of packaging and exchanging digital content in a future Australian data commons – a national corpus of research resources that can be shared and re-used. Whatever packaging format is used, it has to handle complex content models and work across multiple submission and dissemination scenarios. It has to do this in a way that maintains a history of the chain of custody of objects over time. At the start of our journey we chose METS extended by PREMIS to do this. We learnt a lot during the first two stages that we want to share with those travelling to a similar destination.

Descripción de los cambios en los factores de riesgo cardiovascular en pacientes con enfermedad coronaria sometidos a un programa de rehabilitación cardíaca en el Hospital Militar Central en los años 2010-2011

Barragán Noriega, Erling Fabian; Suarez Castro, Paula Andrea; Alvaréz, Oscar Mauricio
Fonte: Universidad Militar Nueva Granada; Facultad de Medicina; Medicina física y rehabilitación Publicador: Universidad Militar Nueva Granada; Facultad de Medicina; Medicina física y rehabilitación
Tipo: bachelorThesis; Trabajo de grado Formato: pdf; pdf
SPA
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Describir la modificación de los factores de riesgo cardiovascular en pacientes con enfermedad coronaria diagnosticada y que culminaron la segunda fase del programa de rehabilitación cardiaca del servicio de Medicina Física y Rehabilitación del Hospital militar central entre los años 2010 a 2011. Metodología: Estudio descriptivo retrospectivo en el cual se realizó la revisión de historias clínicas y registros de sesiones de rehabilitación cardiaca. Mediante la comparación de medias, promedios y asociaciones, se analizaron las variables (colesterol total. LDL, HDL, triglicéridos, glicemia en ayunas, hemoglobina glicosilada (pacientes diabético), METs/min/semana), con el fin de determinar si los cambios evidenciados contribuyen de manera significativa a lograr las metas terapéuticas establecidas en prevención secundaria para pacientes con enfermedad coronaria. Resultados: Ingresaron un total de 143 pacientes al programa de rehabilitación cardiaca de los cuales 68 cumplieron los criterios de inclusión. La edad promedio fue de 67,2 años y el 82.3% pertenecían al género masculino. Se encontró una disminución estadísticamente significativa en los niveles de colesterol total, colesterol LDL, triglicéridos...

Relationship between physical capacity and quality of life in workers university; Capacidad funcional y calidad de vida relacionada con la salud en trabajadores de una institución universitaria; CAPACIDADE FUNCIONAL E QUALIDADE DE VIDA RELACIONADA COM A SAÚDE EM TRABALHADORES DE UMA INSTITUIÇÃO UNIVERSITÁRIA

Uribe Vélez, Yeni Lorena; Dosman González, Viviana Andrea; Triviño Quintero, Lisbeth Patricia; Agredo Zúñiga, Ricardo Antonio; Jerez Valderrama, Alejandra María; Ramírez-Vélez, Robinson María
Fonte: Universidade do Rosário Publicador: Universidade do Rosário
Tipo: Artigo de Revista Científica Formato: application/pdf
Publicado em 03/11/2010 SPA
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Aim: Examine the relationship between the functional capacity and the quality of life related to health in university workers. Methodology: Cross-sectional study in 146 subjects, divided in two groups: Low functional Capacity (< 9 METs) and High functional Capacity (> 9.1 METs). We evaluated quality of life related to health (HRQOL-Health Questionnaire SF-12) and functional capacity (Questionnaire PAR/PAF) as indicators of health status. Results: 47.3% (69 men) and 52.7% (78 women). The average age of the groups was 35.0 ± 9.7 years (range 19,0-60,0 years). For HRQOL, the average found in the population assessed was 45.2 ± 4.42 (range 33,0-58,1) and 43.8 ± 6.87 (range 19,8-43,8) in components Physical Component Summary (PCS-12) and Mental Component Summary (MCS-12), respectively p = NS. Significant differences were found when comparing functional ability and sex, p<0,001 in both groups. Similarly, sex and mental component MCS-12 (group of Lower Functional) p = 0,049 as well as women and the physical component PCS-12, p = 0,05 between groups. Finally, a better score in HRQL observed in the group of High Capacity and functional components in both sex OR 0.59 (0.25-1.38). Conclusions: The results of this study demonstrate the relationship between High functional Capacity and a better HRQOL in this population.; Objetivo: Estudiar la relación entre la capacidad funcional y la calidad de vida relacionada (CVRS) con la salud en un grupo de trabajadores de una institución universitaria. Metodología: Estudio transversal que incluyó 146 trabajadores divididos en dos grupos: Grupo de Baja Capacidad funcional (< 9 METs) y Grupo de Alta Capacidad funcional (> 9...

METS Editor: The Basics, for use with dPanther

Rowan, Kelley F
Fonte: FIU Digital Commons Publicador: FIU Digital Commons
Tipo: text Formato: application/pdf
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This presentation was created for the purpose of an FIU libraries' workshop specifically for administrators of dPanther. This presentation covers specific problems in creating metadata with the METS editor for upload to dPanther and how to resolve these issues.

Introduction to METS – Preservation and Interchange of Digital Objects; Introdução ao METS – Preservação e Intercâmbio de Objetos Digitais 10.5007/1518-2924.2008v13n26p172

Rodrigues, Nelson de Almeida; UnB - Brasília
Fonte: Departamento de Ciência da Informação – UFSC Publicador: Departamento de Ciência da Informação – UFSC
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; Formato: application/pdf
Publicado em 06/10/2008 POR
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The Metadata Encoding & Transmission Standard (METS) is an XML Schema created under the sponsorship of the Digital Library Federation and maintained by the Library of Congress which allows to create a rich structure capable to hold not only the multiple types of metadata used to describe the assets of a digital library, but also the own digital objects, be for management purposes, be to allow an interchange between different institutions. This article presents the motivation problems for its creation and its historical origin in the Making of America II project. Describes the purpose of each XML element that forms the vocabulary of this standard and shows the usage of some of them with XML coded examples, which requires a basic knowledge of that language for better understanding. Expresses its relation with the Open Archival Information System model as a meaningful example of its use and, finally, mentions other standards created with similar purposes.; O Metadata Encoding & Transmission Standard (METS) é um XML Schema elaborado sob o patrocínio da Digital Library Federation e mantido pela Biblioteca do Congresso Norte Americano que permite criar uma rica estrutura capaz de registrar, não apenas os múltiplos tipos de metadados usados para descrever o acervo de uma biblioteca digital...