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Prevalence of diabetes mellitus in the Japanese-Brazilian community of Mombuca, Guatapará, SP; Prevalência do diabetes melito na comunidade nipo-brasileira de Mombuca, Guatapará, SP

ANDRADE, Regina Célia Garcia de; FIGUEIREDO, Roberta Carvalho de; FOSS-FREITAS, Maria Cristina; PACE, Ana Emília; DAL FABBRO, Amaury Lelis; FRANCO, Laércio Joel; FOSS, Milton César
Fonte: Sociedade Brasileira de Endocrinologia e Metabologia Publicador: Sociedade Brasileira de Endocrinologia e Metabologia
Tipo: Relatório
ENG
Relevância na Pesquisa
56.09%
OBJECTIVE: To estimate the prevalence of type 2 diabetes mellitus (DM2) and impaired glucose tolerance (IGT) in the Japanese-Brazilian community of Mombuca in relation to risk factors (FR) for diabetes and cardiovascular disease. SUBJECTS AND METHODS: Cross-sectional study with 131 individuals of Japanese ancestry (69% first generation), aged 20 years or more, submitted to socio-cultural, anthropometric, and biochemistry evaluation. RESULTS: Of the individuals studied (n = 131, age = 55.1 ± 15.9 years), 58.8% were women. The prevalence of DM2 and IGT were 13.7% and 14.5%, respectively. Regarding RF, 76.3% presented dyslipidemia, 52.7% abdominal obesity, 48.1% arterial hypertension, and 42.3% whole body obesity. CONCLUSIONS: The prevalence of DM2, IGT, and RF in this Japanese-Brazilian community was higher than in the adult population of the city of Ribeirão Preto-SP, Brazil, suggesting an increase in risk conditions for these morbidities.; OBJETIVO: Estimar prevalências de diabetes melito tipo 2 (DM2) e tolerância à glicose diminuída (TGD) na comunidade de Mombuca, Guatapará, SP, relacionando-as com fatores de risco (FR) para diabetes e doenças cardiovasculares. SUJEITOS E MÉTODOS: Estudo transversal com 131 nipo-brasileiros (69% de 1ª geração)...

Effects of an intervention in eating habits and physical activity in Japanese-Brazilian women with a high prevalence of metabolic syndrome in Bauru, São Paulo State, Brazil; Efeitos da intervenção em hábitos alimentares e atividade física de mulheres nipo-brasileiras com elevada prevalência de síndrome metabólica, residentes em Bauru, São Paulo, Brasil

FERREIRA, Sandra Roberta G.; GIMENO, Suely G. A.; HIRAI, Amélia T.; HARIMA, Helena; MATSUMURA, Luiza; PITTITO, Bianca de Almeida
Fonte: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz Publicador: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
46.09%
We evaluated the impact of a lifestyle intervention on the cardiometabolic risk profile of women participating in the Study on Diabetes and Associated Diseases in the Japanese-Brazilian Population in Bauru. This was a non-controlled experimental study including clinical and laboratory values at baseline and after a 1-year intervention period. 401 Japanese-Brazilian women were examined (age 60.8±11.7 years), and 365 classified for metabolic syndrome (prevalence = 50.6%). Subjects with metabolic syndrome were older than those without (63.0±10.0 vs. 56.7±11.6 years, p < 0.01). After intervention, improvements in variables were found, except for C-reactive protein. Body mass index and waist circumference decreased, but adiposity reduction was more pronounced in the abdominal region (87.0±9.7 to 84.5±11.2cm, p < 0.001). Intervention-induced differences in total cholesterol, LDL, and post-challenge glucose were significant; women who lost more than 5% body weight showed a better profile than those who did not. The lifestyle intervention in Japanese-Brazilian women at high cardiometabolic risk improved anthropometric and laboratory parameters, but it is not known whether such benefits will persist and result in long-term reduction in cardiovascular events.; Avaliou-se o impacto de intervenção no estilo de vida no perfil de risco cardiometabólico de mulheres participantes do Estudo de Diabetes e Doenças Associadas na População Nipo-Brasileira de Bauru. O delineamento foi experimental não-controlado...

Fat and fiber consumption are associated with peripheral arterial disease in a cross-sectional study of a Japanese-Brazilian population

GIMENO, Suely Godoy Agostinho; HIRAI, Amelia Toyomi; HARIMA, Helena Aiko; KIKUCHI, Mario Yasuo; SIMONY, Rosana Farah; BARROS JR., Newton de; CARDOSO, Marly A.; FERREIRA, Sandra Roberta Gouvea
Fonte: JAPANESE CIRCULATION SOC Publicador: JAPANESE CIRCULATION SOC
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
46.05%
Background The Western diet plays a role for the epidemics of obesity and related diseases. This study examined a possible association between peripheral arterial disease (PAD) and the dietary components of Japanese immigrants living in Brazil. Methods and Results In this cross-sectional study, 1,267 subjects (aged 30 years) with complete dietary, clinical and laboratory data were studied according to a standardized protocol. Ankle-to-brachial index was used to identify subjects with PAD. The overall prevalence of PAD was 14.6%. Subjects with PAD were older, had lower education and higher mean values of blood pressure, triglycerides, and fasting and 2-h plasma glucose levels compared with those without the disease. Among the subjects with PAD, the consumption of fiber from whole grains (3.0 vs 3.4g, p=0.001) and linoleic acids (11.0 vs 11.7g, p=0.017) were lower and intake of total (72.8 vs 69.1 a, p=0.016) and saturated fatty acids (17.4 vs 16.3g, p=0.012) were higher than those without PAD. Results of multiple logistic regression analysis showed a significant association between PAD with high total fat intake, low intake of fiber from fruit and oleic acid, independently of other variables. Conclusions Despite limitations in examining the cause-effect relationship...

Nutritional intervention programme among a Japanese-Brazilian community: procedures and results according to gender

DAMIAO, Renata; SARTORELLI, Daniela Saes; HIRAI, Amelia; MASSIMINO, Flavia; POLETTO, Juliana; BEVILACQUA, Marselle Rodrigues; CHAIM, Rita; SALVO, Vera Lucia Morais Antonio de; ASAKURA, Leiko; FERREIRA, Sandra Roberta Gouveia; ANDREONI, Solange; GIMENO, Su
Fonte: CAMBRIDGE UNIV PRESS Publicador: CAMBRIDGE UNIV PRESS
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
46.06%
Objective: To describe the results of a nutritional intervention programme among Japanese-Brazilians according to gender. Design: A non-controlled experimental study. Setting: The research included three points of clinical, nutritional and physical activity evaluation: at baseline (in 2005), after the first year and at the end of the second year (in 2007). The paired Student t test and multiple linear regression analysis were used to evaluate changes in the subjects` profile (clinical, nutritional and physical activity variables). Subjects: Japanese-Brazilians (n 575) of both genders, aged over 30 years. Results: We verified statistically significant reductions in body weight (0.9 kg), waist circumference (2.9 cm), blood pressure, fasting blood glucose (>3 mg/dl) and total cholesterol (>20 mg/dl) and its fractions, in both genders. We also found reductions in intake of energy (among men), protein (among women) and fat (both genders) and increases in intake of total fibre (among women) and carbohydrate (among men). Conclusions: The intervention programme indicated meaningful benefits for the intervention subjects, with changes in their habits that led to a `healthier` lifestyle positively impacting their nutritional and metabolic profile.; Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP)[2005/59178-7]; Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)[505845/2004-0]

Association of genetic variants in the adiponectin encoding gene (ADIPOQ) with type 2 diabetes in Japanese Brazilians

VENDRAMINI, Marcio F.; PEREIRA, Alexandre C.; FERREIRA, Sandra R.; KASAMATSU, Teresa S.; MOISES, Regina S.; Japanese Brazilian Diabet Study Gr
Fonte: ELSEVIER SCIENCE INC Publicador: ELSEVIER SCIENCE INC
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
76.17%
Aim: The objective of this study is to assess the contribution of ADIPOQ variants to type 2 diabetes in Japanese Brazilians. Methods: We genotyped 200 patients with diabetes mellitus (100 male and 100 female, aged 55.0 years [47.5-64.0 years]) and 200 control subjects with normal glucose tolerant (NGT) (72 male and 128 female, aged 52.0 years [43.5-64.5 years]). Results: Whereas each polymorphism studied (T45G, G276T, and A349G) was not significantly associated with type 2 diabetes mellitus, the haplotype GGA was overrepresented in our diabetic population (9.3% against 3.1% in NGT individuals, P=.0003). Also, this haplotype was associated with decreased levels of adiponectin. We also identified three mutations in exon 3: I164T, R221S, and H241P, but, owing to the low frequencies of them, associations with type 2 diabetes could not be evaluated. The subjects carrying the R221S mutation had plasma adiponectin levels lower than those without the mutation (2.10 mu g/ml [1.35-2.55 mu g/ml] vs. 6.68 mu g/ml [3.90-11.23 mu g/ml], P=.015). Similarly, the I164T mutation carriers had mean plasma adiponectin levels lower than those noncarriers (3.73 mu g/ml [3.10-4.35 mu g/ml] vs. 6.68 mu g/ml [3.90-11.23 mu g/ml]), but this difference was not significant (P=.17). Conclusions: We identified in the ADIPOQ gene a risk haplotype for type 2 diabetes in the Japanese Brazilian population. (C) 2010 Elsevier Inc. All rights reserved.; Fundacao de Amparo a Pesquisa do Estado de Sao Paulo...

Dietary omega-3 fatty acid and omega-3: omega-6 fatty acid ratio predict improvement in glucose disturbances in Japanese Brazilians

SARTORELLI, Daniela S.; DAMIAO, Renata; CHAIM, Rita; HIRAI, Amelia; GIMENO, Suely G. A.; FERREIRA, Sandra R. G.; Japanese Brazilian Diabet Study Gr
Fonte: ELSEVIER SCIENCE INC Publicador: ELSEVIER SCIENCE INC
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
46.02%
Objective: We investigated whether lifestyle-induced changes in dietary fat quality are related to Improvements on glucose metabolism disturbances in Japanese Brazilians at high risk of type 2 diabetes Methods: One hundred forty-eight first- and second-generation subjects with impaired glucose tolerance or impaired fasting glycemia who attended a lifestyle intervention program for 12 mo were studied in the city of Bauru. State of Sao Paulo, Brazil Dietary fatty acid intakes at baseline and after 12 mo were estimated using three 24-h recalls. The effect of dietary fat intake on glucose metabolism was investigated by multiple logistic regression models Results: At baseline, mean standard deviation age and body mass index were 60 II y and 25 5 4.2 kg/m2, respectively After 12 mo. 92 subjects had normal plasma glucose levels and 56 remained in prediabetic conditions. Using logistic regression models adjusted for age, gender, generation, basal intake of explanatory nutrient, energy intake, physical activity, and waist circumference, the odds ratios (95% confidence intervals) for reversion to normoglycemia were 3 14 (1 22-8 10) in the second wrote of total w-3 fatty acid, 4 26 (1.34-13 57) in the second tunic of eicosapentaenoic acid, and 280 (1 10-7.10) in the second tertile of linolenic acid. Similarly. subjects in the highest wrote of w-3.w-6 fatty acid ratio showed a higher chance of improving glucose disturbances (2 51...

Novel mutation in the adiponectin (ADIPOQ) gene is associated with hypoadiponectinaemia in Japanese-Brazilians

VENDRAMINI, Marcio F.; KASAMATSU, Teresa S.; CRISPIM, Felipe; FERREIRA, Sandra R.; MATIOLI, Sergio R.; MOISES, Regina S.; Japanese-Brazilian Diabet Study
Fonte: WILEY-BLACKWELL PUBLISHING, INC Publicador: WILEY-BLACKWELL PUBLISHING, INC
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
56.21%
P>Objective Adiponectin is an important mediator of insulin sensitivity, encoded by the ADIPOQ gene. Here we describe two Japanese-Brazilian families with hypoadiponectinaemia due to a novel mutation in ADIPOQ. Design and patients In this study, we examined the entire translated regions of adiponectin in Japanese-Brazilians, a population with one of the highest prevalence rates of diabetes worldwide. We screened 200 patients with type 2 diabetes (DM) and 240 age-matched subjects with normal glucose tolerance. Results A novel heterozygous T deletion at position 186 in exon 2 of ADIPOQ, causing a frameshift at codon 62 and leading to a premature termination at codon 168 (p.Gly63ValfsX106), was found in two individuals with diabetes. This mutation was not found in 240 nondiabetic control subjects. In addition, we screened the mutation in an expanded set of 100 nondiabetic subjects from the general Brazilian population, but we found no mutations. In addition, six family members of the probands were identified as mutation-carriers. Individuals who were mutation-carriers had markedly low plasma adiponectin concentrations compared with those without the mutation [DM: 0 center dot 65 (0 center dot 59-1 center dot 34) mu g/ml vs. 5 center dot 30 (3 center dot 10-8 center dot 55) mu g/ml...

Estudo comparativo do padrão cefalométrico dos jovens mestiços nipo-brasileiros - grandezas tegumentares e esqueléticas; Comparative study of the cephalometric norms for Japanese Japanese-Brazilian descents skeletal and soft tissue measurements

Fernandes, Thais Maria Freire
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 20/02/2009 PT
Relevância na Pesquisa
46.25%
Introdução: Em virtude da miscigenação populacional que ocorre no Brasil, os diferentes grupos étnicos podem apresentar estruturas esqueléticas craniofaciais e tegumentares distintas. Nesse sentido, estudos devem ser estabelecidos para suportar o diagnóstico e facilitar o plano de tratamento entre as diferentes raças e seus diferentes padrões de miscigenação. Objetivo: Determinar os valores médios de normalidade das grandezas cefalométricas tegumentares e esqueléticas de jovens brasileiros mestiços nipo-brasileiros, com oclusão normal descendentes de japoneses e brasileiros e comparar os resultados das variáveis com amostras compatíveis de jovens brasileiros leucodermas e xantodermas. Material e Métodos: Foram utilizadas 40 telerradiografias de jovens leucodermas, 32 de nipo-brasileiros e 33 de xantodermas. As três amostras apresentavam indivíduos com oclusão normal e face bem balanceada. Devido às características do tecido mole e para facilitar a comparação, as amostras foram divididas por gênero. Foram realizados os testes estatísticos: análise de variância a um critério (ANOVA), teste t e a análise de covariância (ANCOVA). Resultados: Encontrou-se diferença estatística (p<0,05) entre as três raças em 17 variáveis para o gênero feminino e 15 para o gênero masculino. Essas variáveis evidenciaram menor espessura na região do násio; menor nariz e biprotrusão labial para as meninas nipobrasileiras em relação aos leucodermas e maior espessura na região da glabela; menor espessura na região do násio; maior espessura do lábio inferior e da região supramentoniana e padrão esquelético facial mais vertical para os meninos nipobrasileiros. Conclusão: As meninas nipo-brasileiras apresentaram características mais similares com a amostra xantoderma e os meninos nipo-brasileiros apresentaram valores numericamente intermediários...

Esboço do atlas do falar dos nipo-brasileiros do Distrito Federal: aspecto semântico-lexical; Atlas sketch of the Distrito Federal Japanese-Brazilian speaking: semantic-lexical aspect

Takano, Yuko
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 25/03/2013 PT
Relevância na Pesquisa
66.25%
A presente tese tem como objetivo descrever o falar nipo-brasileiro em cinco comunidades do Distrito Federal com vistas à construção do Esboço do Atlas do Falar dos Nipo-Brasileiros do Distrito Federal: aspecto semântico-lexical. O contato de línguas (português versus japonês), cada vez mais estreito, acarreta mudanças expressivas no cenário linguístico e se manifesta na fala dos nipo-brasileiros, cuja situação evidencia o entrelaçamento de duas línguas que se aliam e se alinham, configurando uma nova forma de uso que denominamos variedade nipobrasileira, objeto desta pesquisa. Essa fala é sustentada pela história linguística de (i)migrantes e seus descendentes e percorre seu curso natural de língua em constante movimento, criando, assim, situações linguísticas próprias. Diante deste fato, faz-se necessário resgatar e registrar esse uso, uma vez que a fala simboliza, em parte, a identidade linguística deste grupo social. A presente tese busca registrar e descrever a variedade nipobrasileira quanto ao componente semântico-lexical. Para a coleta de dados recorre-se a procedimentos metodológicos da Geolinguística. Selecionam-se cinco comunidades, pontos da pesquisa Brasília; Brazlândia; Núcleo Bandeirante; Taguatinga e Vargem Bonita com base não apenas em fatores históricos relacionados à (i)migração japonesa no Planalto Central...

Autoimmunity does not contribute to the highly prevalent glucose metabolism disturbances in a Japanese Brazilian population

Hashimoto, Silvia M.; Hirai, A. T.; Kikuchi, M.; Cardoso, M. A.; Tomita, N.; Chaim, R.; Wakisaka, K.; Gimeno, Suely G.A.; Matsumura, Luiza; Franco, Laercio J.; Miranda, Walkiria L.; Ferreira, Sandra R.G.; Osiro, K.; Iunes, M.; De Barros Junior, Newton
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Artigo de Revista Científica Formato: 78-83
ENG
Relevância na Pesquisa
56.12%
The Japanese Brazilian population has one of the highest prevalences of diabetes worldwide. Despite being non-obese according to standard definitions, their body fat distribution is typically central. We investigated whether a subset of these subjects had autoantibodies that would suggest a slowly progressive form of type 1 diabetes. A total of 721 Japanese Brazilians (386 men) in the 30- to 60-year age group underwent clinical examination and laboratory procedures, including a 75-g oral glucose tolerance test and determinations of serum autoantibodies. Antibodies to glutamic acid decarboxylase (GADab) were determined by radioimmunoassay and to thyroglobulin (TGab) and thyroperoxidase (TPOab) by flow-cytometry assays. Mean body mass index was 25.2 ± 3.8 kg/m2, but waist circumference was elevated according to the Asian standards. Diabetes, impaired glucose tolerance, and impaired fasting glycemia were found in 31%, 22%, and 22%, respectively, and 53% of the subjects had metabolic syndrome. Glutamic acid decarboxylase (GADab) was positive in 4.72%, TGab in 9.6%, and TPOab in 10% of the whole sample. When participants were stratified according to the presence of thyroid antibodies, similar frequencies of GADab were found in positive and negative groups. The prevalence rates of glucose metabolism disturbances did not differ between GADab positive and negative groups. Our data did not support the view that autoimmune injury could contribute to the high prevalence of diabetes seen in Japanese Brazilians...

Analysis of criteria for metabolic syndrome in a population-based study of Japanese-Brazilians

Rosenbaum, P.; Gimeno, SGA; Sanudo, A.; Franco, L. J.; Ferreira, SRG; Japanese-Brazilian Diabetes Grp
Fonte: Blackwell Publishing Publicador: Blackwell Publishing
Tipo: Artigo de Revista Científica Formato: 352-359
ENG
Relevância na Pesquisa
66.24%
Objective: Criteria for metabolic syndrome (MS) differ particularly regarding the definition of central obesity and consequently, there could be differences in the assessment of cardiovascular risk. We estimated the prevalence of metabolic syndrome, compared the agreement of the World Health Organization (WHO) criteria with the standard and a modified National Cholesterol Education Program (NCEP) criterion and investigated whether additional factors were associated with the diagnosis of the syndrome in a Japanese descendant population.Methods: In this cross-sectional, population-based survey, 1166 Japanese-Brazilians (533 men, 633 women) aged 57.4 +/- 12.4 years with mean body mass index (BMI) and waist of 25.2 +/- 4.0 kg/m(2) and 84.5 +/- 10.6 cm, respectively, were included. McNemar and kappa statistics were used to assess the concordance between WHO criteria with the standard and a modified NCEP criteria (waist of 90 and 80 cm, for men and women, respectively). in logistic regression analysis, a number of metabolic variables and albumin-to-creatinine ratio were included to test independent associations with metabolic syndrome defined by the modified NCEP criteria.Results: According to WHO, 55.4% (95% Cl 52.5-58.2%) of the subjects had MS and to NCEP 47.4% (95% Cl 44.6-50.0%). WHO criterion detected 48.3% of central obese subjects while NCEP only 14.0%. Kappa statistics showed a good strength of agreement (k = 0.67...

Prevalence of diabetes mellitus in the Japanese-Brazilian community of Mombuca, Guatapará, SP

Andrade,Regina Célia Garcia de; Figueiredo,Roberta Carvalho de; Foss-Freitas,Maria Cristina; Pace,Ana Emília; Dal Fabbro,Amaury Lelis; Franco,Laércio Joel; Foss,Milton César
Fonte: Sociedade Brasileira de Endocrinologia e Metabologia Publicador: Sociedade Brasileira de Endocrinologia e Metabologia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/03/2011 EN
Relevância na Pesquisa
56.09%
OBJECTIVE: To estimate the prevalence of type 2 diabetes mellitus (DM2) and impaired glucose tolerance (IGT) in the Japanese-Brazilian community of Mombuca in relation to risk factors (FR) for diabetes and cardiovascular disease. SUBJECTS AND METHODS: Cross-sectional study with 131 individuals of Japanese ancestry (69% first generation), aged 20 years or more, submitted to socio-cultural, anthropometric, and biochemistry evaluation. RESULTS: Of the individuals studied (n = 131, age = 55.1 ± 15.9 years), 58.8% were women. The prevalence of DM2 and IGT were 13.7% and 14.5%, respectively. Regarding RF, 76.3% presented dyslipidemia, 52.7% abdominal obesity, 48.1% arterial hypertension, and 42.3% whole body obesity. CONCLUSIONS: The prevalence of DM2, IGT, and RF in this Japanese-Brazilian community was higher than in the adult population of the city of Ribeirão Preto-SP, Brazil, suggesting an increase in risk conditions for these morbidities.

Association between peripheral arterial disease and creactive protein in the japanese-brazilian population

Garofolo,Luciana; Ferreira,Sandra Roberta G.; Miranda Júnior,Fausto
Fonte: Colégio Brasileiro de Cirurgiões Publicador: Colégio Brasileiro de Cirurgiões
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/2014 EN
Relevância na Pesquisa
46.03%
OBJECTIVE: To evaluate the relationship between peripheral arterial disease and elevated levels of C-reactive protein in the Japanese-Brazilian population of high cardiovascular risk. METHODS: We conducted a cross-sectional study derived from a population-based study on the prevalence of diabetes and associated diseases in the Japanese-Brazilian population. One thousand, three hundred and thirty individuals aged e" 30 underwent clinical and laboratory examination, including measurement of ultrasensitive C-reactive protein. The diagnosis of peripheral arterial disease was performed by calculating the ankle-brachial index. We considered with peripheral arterial disease patients who had ankle-brachial index d" 0.9. After applying the exclusion criteria, 1,038 subjects completed the study. RESULTS: The mean age of the population was 56.8 years; 46% were male. The prevalence of peripheral arterial disease was 21%, with no difference between genders. Data analysis showed no association between peripheral arterial disease and ultrasensitive C-reactive protein. Patients with ankle-brachial index d" 0.70 showed higher values of ultrasensitive C-reactive protein and worse cardiometabolic profile. We found a positive independent association of peripheral arterial disease with hypertension and smoking. CONCLUSION: The association between low levels of ankle-brachial index and elevated levels of ultrasensitive C-reactive protein may suggest a relationship of gravity...

Leptin is not associated independently with hypertension in Japanese-Brazilian women

Almeida-Pititto,B.; Gimeno,S.G.A.; Freire,R.D.; Ribeiro-Filho,F.F.; Ferreira,S.R.G.
Fonte: Associação Brasileira de Divulgação Científica Publicador: Associação Brasileira de Divulgação Científica
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2006 EN
Relevância na Pesquisa
46.11%
We evaluated the relationship of leptin with hypertension adjusted for body mass index (BMI) and/or waist circumference in a population of Japanese-Brazilian women aged > or = 30 years with centrally distributed adiposity. After excluding diabetic subjects, the study subjects - who participated in a population-based study on the prevalence of metabolic syndrome - showed prevalence rates of obesity (BMI > or = 25 kg/m²) and central adiposity (waist > or = 80 cm) of 32.0 and 37.8%, respectively. The hypertensive group (N = 162) was older, had higher BMI (24.9 ± 4.2 vs 23.3 ± 3.4 kg/m², P < 0.001), waist circumference (81.1 ± 10.1 vs 76.3 ± 8.2 cm, P < 0.001) and insulin levels (8.0 ± 6.2 vs 7.1 ± 4.9 µU/mL, P < 0.05) than the normotensive group (N = 322) and showed an unfavorable metabolic profile (higher 2-h plasma glucose, C-reactive protein and non-HDL cholesterol levels). Leptin did not differ between groups (8.2 ± 6.8 vs 7.2 ± 6.6 ng/mL, P = 0.09, for hypertensive vs normotensive, respectively) and its levels correlated significantly with anthropometric variables but not with blood pressure. Logistic regression analysis indicated that age and waist were independently associated with hypertension but not with homeostasis model assessment of insulin resistance or leptin levels. The lack of an independent association of hypertension with metabolic parameters (2-h glucose...

Effects of an intervention in eating habits and physical activity in Japanese-Brazilian women with a high prevalence of metabolic syndrome in Bauru, São Paulo State, Brazil

Ferreira,Sandra Roberta G.; Gimeno,Suely G. A.; Hirai,Amélia T.; Harima,Helena; Matsumura,Luiza; Pittito,Bianca de Almeida
Fonte: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz Publicador: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2008 EN
Relevância na Pesquisa
46.09%
We evaluated the impact of a lifestyle intervention on the cardiometabolic risk profile of women participating in the Study on Diabetes and Associated Diseases in the Japanese-Brazilian Population in Bauru. This was a non-controlled experimental study including clinical and laboratory values at baseline and after a 1-year intervention period. 401 Japanese-Brazilian women were examined (age 60.8±11.7 years), and 365 classified for metabolic syndrome (prevalence = 50.6%). Subjects with metabolic syndrome were older than those without (63.0±10.0 vs. 56.7±11.6 years, p < 0.01). After intervention, improvements in variables were found, except for C-reactive protein. Body mass index and waist circumference decreased, but adiposity reduction was more pronounced in the abdominal region (87.0±9.7 to 84.5±11.2cm, p < 0.001). Intervention-induced differences in total cholesterol, LDL, and post-challenge glucose were significant; women who lost more than 5% body weight showed a better profile than those who did not. The lifestyle intervention in Japanese-Brazilian women at high cardiometabolic risk improved anthropometric and laboratory parameters, but it is not known whether such benefits will persist and result in long-term reduction in cardiovascular events.

Cardiovascular risk in Japanese-Brazilian subjects; Risco cardiovascular em nipobrasileiros

Gomes, Patricia Moreira; Andrade, Regina Celia Garcia de; Figueiredo, Roberta Carvalho de; Pace, Ana Emilia; Fabbro, Amaury Lelis Dal; Franco, Laercio Joel; Foss, Milton Cesar; Freitas, Maria Cristina Foss
Fonte: SBEM-SOC BRASIL ENDOCRINOLOGIA & METABOLOGIA; RIO DE JANEIRO Publicador: SBEM-SOC BRASIL ENDOCRINOLOGIA & METABOLOGIA; RIO DE JANEIRO
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
96.19%
Objective: To evaluate the prevalence of risk factors for cardiovascular disease in Japanese-Brazilian subjects. Subjects and methods: One hundred thirty-one residents of the Mombuca community were studied. Statistical analysis was based on the X-2 test, Fisher's Exact test, Student's t test, and ANOVA, at a 5% significance level. Results: The average age was 56.7 years-old; 76.3% had dyslipidemia, 24.4% pre-diabetes (PDM), 10.7% type 2 diabetes mellitus (T2DM), 46.6% hypertension, 52.7% abdominal obesity, and 35.8% metabolic syndrome (MS). There were significant correlations between HOMA-IR and MS diagnosis and obesity, while HOMA-beta levels were decreased in T2DM and PDM. The ankle-brachial index was positive for peripheral artery disease in 22.3% of the individuals. Electrocardiograms did not show increased evidence of myocardial ischemia. Conclusion: Subjects of this community are exposed to major cardiovascular risk factors, namely high prevalence of MS diagnoses and increased HOMA-IR. Arq Bras Endocrinol Metab. 2012; 56(9): 608-13; Objetivo: Avaliar a presença de fatores de risco para doença cardiovascular em nipo-brasileiros. Sujeitos e métodos: Foram estudados 131 moradores de Mombuca. Utilizaram-se os testes do Qui-quadrado...

Cardiovascular risk in Japanese-Brazilian subjects; Risco cardiovascular em nipobrasileiros

Gomes, Patricia Moreira; Andrade, Regina Célia Garcia de; Figueiredo, Roberta Carvalho de; Pace, Ana Emília; Dal Fabbro, Amaury Lelis; Franco, Laércio Joel; Foss, Milton César; Foss-Freitas, Maria Cristina
Fonte: Sociedade Brasileira de Endocrinologia e Metabologia Publicador: Sociedade Brasileira de Endocrinologia e Metabologia
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
96.19%
OBJECTIVE: To evaluate the prevalence of risk factors for cardiovascular disease in Japanese-Brazilian subjects. SUBJECTS AND METHODS: One hundred thirty-one residents of the Mombuca community were studied. Statistical analysis was based on the X² test, Fisher's Exact test, Student's t test, and ANOVA, at a 5% significance level. RESULTS: The average age was 56.7 years-old; 76.3% had dyslipidemia, 24.4% pre-diabetes (PDM), 10.7% type 2 diabetes mellitus (T2DM), 46.6% hypertension, 52.7% abdominal obesity, and 35.8% metabolic syndrome (MS). There were significant correlations between HOMA-IR and MS diagnosis and obesity, while HOMA-β levels were decreased in T2DM and PDM. The ankle-brachial index was positive for peripheral artery disease in 22.3% of the individuals. Electrocardiograms did not show increased evidence of myocardial ischemia. CONCLUSION: Subjects of this community are exposed to major cardiovascular risk factors, namely high prevalence of MS diagnoses and increased HOMA-IR. Arq Bras Endocrinol Metab. 2012;56(9):608-13

Cardiovascular risk in Japanese-Brazilian subjects

Gomes,Patricia Moreira; Andrade,Regina Célia Garcia de; Figueiredo,Roberta Carvalho de; Pace,Ana Emília; Dal Fabbro,Amaury Lelis; Franco,Laércio Joel; Foss,Milton César; Foss-Freitas,Maria Cristina
Fonte: Sociedade Brasileira de Endocrinologia e Metabologia Publicador: Sociedade Brasileira de Endocrinologia e Metabologia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2012 EN
Relevância na Pesquisa
96.19%
OBJECTIVE: To evaluate the prevalence of risk factors for cardiovascular disease in Japanese-Brazilian subjects. SUBJECTS AND METHODS: One hundred thirty-one residents of the Mombuca community were studied. Statistical analysis was based on the X² test, Fisher's Exact test, Student's t test, and ANOVA, at a 5% significance level. RESULTS: The average age was 56.7 years-old; 76.3% had dyslipidemia, 24.4% pre-diabetes (PDM), 10.7% type 2 diabetes mellitus (T2DM), 46.6% hypertension, 52.7% abdominal obesity, and 35.8% metabolic syndrome (MS). There were significant correlations between HOMA-IR and MS diagnosis and obesity, while HOMA-β levels were decreased in T2DM and PDM. The ankle-brachial index was positive for peripheral artery disease in 22.3% of the individuals. Electrocardiograms did not show increased evidence of myocardial ischemia. CONCLUSION: Subjects of this community are exposed to major cardiovascular risk factors, namely high prevalence of MS diagnoses and increased HOMA-IR. Arq Bras Endocrinol Metab. 2012;56(9):608-13

Condições periodontais e diabetes mellitus na população nipo-brasileira; Periodontal conditions and diabetes mellitus in the Japanese-Brazilian population

Tomita, Nilce E; Chinellato, Luiz E M; Pernambuco, Renata A; Lauris, José Roberto P; Franco, Laércio J
Fonte: Universidade de São Paulo. Faculdade de Saúde Pública Publicador: Universidade de São Paulo. Faculdade de Saúde Pública
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; ; Formato: application/.pdf
Publicado em 01/10/2002 POR
Relevância na Pesquisa
46.04%
OBJETIVO: Avaliar as condições periodontais e sua relação com o diabetes mellitus na população nipo-brasileira. MÉTODOS: Foram examinados 1.315 indivíduos do município de Bauru, SP, na faixa etária de 30 a 92 anos de idade, ambos os sexos, primeira (Isseis) e segunda (Niseis) gerações. Os critérios de exclusão da amostra foram o edentulismo total e a presença de seis sextantes nulos. O índice periodontal comunitário e o índice de perda de inserção periodontal foram obtidos mediante sondagem em 10 dentes-índice, em uma amostra de 831 indivíduos. O diagnóstico de diabetes mellitus foi estabelecido através da glicemia em jejum e de duas horas após sobrecarga com 75 g de glicose. Para análise estatística foram utilizados os Testes de Kappa e de Qui-quadrado. RESULTADOS: Quanto às condições periodontais, foram encontrados 25,5% de indivíduos sadios, 12,5% com sangramento à sondagem, 49,4% com presença de cálculo, 10,4% com bolsas superficiais, 2,2% com bolsas profundas. Apresentaram perdas de inserção periodontal de 0-3 mm, 24,2% dos indivíduos, de 4-5 mm, 36,7%, de 6-8 mm, 23,7%, de 9-11 mm, 11,3% e de 12 mm ou mais, 4,1%. A avaliação entre diabetes e condições periodontais não apresentou associação estatística (p; OBJECTIVE: To evaluate the relationship between diabetic status and periodontal conditions in the Japanese-Brazilian population. METHODS: The sample consisted of 1...

Effects of an intervention in eating habits and physical activity in Japanese-Brazilian women with a high prevalence of metabolic syndrome in Bauru, São Paulo State, Brazil

Ferreira,Sandra Roberta G.; Gimeno,Suely G. A.; Hirai,Amélia T.; Harima,Helena; Matsumura,Luiza; Pittito,Bianca de Almeida
Fonte: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz Publicador: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2008 EN
Relevância na Pesquisa
46.09%
We evaluated the impact of a lifestyle intervention on the cardiometabolic risk profile of women participating in the Study on Diabetes and Associated Diseases in the Japanese-Brazilian Population in Bauru. This was a non-controlled experimental study including clinical and laboratory values at baseline and after a 1-year intervention period. 401 Japanese-Brazilian women were examined (age 60.8±11.7 years), and 365 classified for metabolic syndrome (prevalence = 50.6%). Subjects with metabolic syndrome were older than those without (63.0±10.0 vs. 56.7±11.6 years, p < 0.01). After intervention, improvements in variables were found, except for C-reactive protein. Body mass index and waist circumference decreased, but adiposity reduction was more pronounced in the abdominal region (87.0±9.7 to 84.5±11.2cm, p < 0.001). Intervention-induced differences in total cholesterol, LDL, and post-challenge glucose were significant; women who lost more than 5% body weight showed a better profile than those who did not. The lifestyle intervention in Japanese-Brazilian women at high cardiometabolic risk improved anthropometric and laboratory parameters, but it is not known whether such benefits will persist and result in long-term reduction in cardiovascular events.