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Clinical and haemodynamic evaluation of chronic thromboembolic pulmonary hypertension patients scheduled for pulmonary thromboendarterectomy: Is schistosomiasis hypertension an important confounding factor?

TERRA-FILHO, Mario; MELLO, Marcos Figueiredo; LAPA, Mônica Silveira; TEIXEIRA, Ricardo Henrique Oliveira Braga; JATENE, Fábio Biscegli
Fonte: Faculdade de Medicina / USP Publicador: Faculdade de Medicina / USP
Tipo: Artigo de Revista Científica
ENG
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INTRODUCTION: Chronic thromboembolic pulmonary hypertension is a disease affecting approximately 4,000 people per year in the United States. The incidence rate in Brazil, however, is unknown. The estimated survival for patients with chronic thromboembolic pulmonary hypertension without treatment is approximately three years. Pulmonary thromboendarterectomy for select patients is a potentially curative procedure when correctly applied. In Brazil, the clinical and hemodynamic profiles of chronic thromboembolic pulmonary hypertension patients have yet to be described. OBJECTIVES: To evaluate the clinical and hemodynamic characteristics of chronic thromboembolic pulmonary hypertension patients scheduled for pulmonary thromboendarterectomy in a referral center for chronic thromboembolic pulmonary hypertension treatment in Brazil. METHODS: From December 2006 to November 2009, patients were evaluated and scheduled for pulmonary thromboendarterectomy. The subjects were classified according to gender, age and functional class and were tested for thrombofilia and brain natriuretic peptide levels. RESULTS: Thirty-five consecutive chronic thromboembolic pulmonary hypertension patients were evaluated. Two patients tested positive for schistosomiasis...

The Effects of Continuous Positive Airway Pressure on Prehypertension and Masked Hypertension in Men With Severe Obstructive Sleep Apnea

DRAGER, Luciano F.; PEDROSA, Rodrigo P.; DINIZ, Patricia M.; DIEGUES-SILVA, Luzia; MARCONDES, Bianca; COUTO, Roberta B.; GIORGI, Dante M. A.; KRIEGER, Eduardo M.; LORENZI-FILHO, Geraldo
Fonte: LIPPINCOTT WILLIAMS & WILKINS Publicador: LIPPINCOTT WILLIAMS & WILKINS
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
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Obstructive sleep apnea and hypertension are common conditions that frequently coexist. Continuous positive airway pressure (CPAP) reduces blood pressure in patients with obstructive sleep apnea and sustained hypertension. However, the impact of CPAP on patients with obstructive sleep apnea and prehypertension and masked hypertension, conditions associated with increased cardiovascular risk, is unknown. Thirty-six male patients (age, 43 +/- 7 years; body mass index, 28.8 +/- 3.0 kg/m(2)) with untreated severe obstructive sleep apnea (apnea-hypopnea index, 56 +/- 22 events/hr on polysomnography) with diagnostic criteria for prehypertension and/or masked hypertension, based on office and 24-hour ambulatory blood pressure monitoring, respectively, were studied. The patients randomized to no treatment (control; n=18) or CPAP (n=18) for 3 months had similar frequency of prehypertension and masked hypertension at study entry. There were no significant changes in blood pressure in patients randomized to the control group. In contrast, patients randomized to CPAP presented significant reduction in office systolic (from 126 +/- 5 to 121 +/- 7 mm Hg; P=0.001) and a trend for diastolic blood pressure (from 75 +/- 7 to 73 +/- 8 mm Hg; P=0.08) as well as a significant decrease in daytime and nighttime systolic and diastolic blood pressure (P < 0.05 for each comparison). There was a significant reduction in the frequency of prehypertension (from 94% to 55%; P=0.02) and masked hypertension (from 39% to 5%; P=0.04) only in the CPAP group. In conclusion...

Efeitos da lercanidipina sobre alterações cardiovasculares presentes em modelos de Hipertensão Arterial e Diabetes Mellitus em ratos; Effects of lercanidipine on the cardiovascular alterations in animal models of arterial hypertension and diabetes mellitus in mice

Martinez, Márcio Luís Lombardi
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 05/08/2008 PT
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Hipertensão e Diabetes são dois dos principais fatores de risco para o desenvolvimento de aterosclerose e doença da artéria coronária. Tais enfermidades aumentam o risco cardiovascular a índices muito elevados, e são acompanhadas por uma alteração fisiopatológica comum, que é o remodelamento vascular acelerado, caracterizado pelo desarranjo na regulação da atividade das metaloproteinases (MMPs) associado ao aumento do "stress" oxidativo. Um dos modelos mais semelhantes ao quadro de hipertensão renovascular em humanos é o modelo de hipertensão renovascular unilateral (2R-1C), que é produzido pelo clampeamento de uma das artérias renais, e manutenção do rim contra lateral intacto. Por outro lado, a Aloxana tem sido extensivamente utilizada como modelo de indução química dos tipos de diabetes não-insulino dependentes. Este remodelamento vascular acelerado presente na hipertensão bem como na diabetes está associado a ativação de um grupo de endopeptidases zinco-dependentes denominadas metaloproteinases, que têm sido implicadas no remodelamento vascular subjacente à aterosclerose. MMPs têm sido reconhecidas como um grupo de enzimas envolvidas na degradação de componentes da matriz extracelular em processo fisiológicos...

Fatores genéticos associados à hipertensão essencial em populações remanescentes de quilombos do Vale do Ribeira - São Paulo; Genetic risk factors associated with essential hypertension in the quilombo populations from Ribeira River Valley - São Paulo, Brazil

Kimura, Lilian
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 09/12/2010 PT
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A hipertensão essencial, um problema de saúde pública mundial, é uma doença multifatorial, cujo componente genético varia entre 25 a 60%. A despeito da alta prevalência e incidência da hipertensão essencial em populações de ancestralidade africana, os estudos sobre o componente genético da hipertensão essencial têm sido primariamente realizados em populações de ancestralidade européia ou asiática. Dessa maneira, o objetivo geral deste trabalho foi investigar e quantificar potenciais fatores de risco genéticos associados à hipertensão essencial em populações dos remanescentes de quilombos do Vale do Ribeira SP, indivíduos afro-descendentes, oriundos de populações parcialmente isoladas, previamente bem caracterizadas do ponto de vista clínico, genealógico e genético-populacional. A amostra foi constituída de 759 indivíduos adultos com estudo clínico e antropométrico oriundos das seguintes populações quilombolas: Abobral, Galvão, São Pedro, Pedro Cubas, André Lopes, Nhunguara, Sapatu, Pilões, Ivaporunduva, Maria Rosa, Poça e Reginaldo, localizadas no Vale do Ribeira, no estado de São Paulo. Estimativas de ancestralidade (baseadas em 48 marcadores INDEL autossômicos) sugerem que a contribuição africana...

Padrões da dieta e hipertensão em adultos e idosos de São Paulo; Dietary patterns and hypertension among adults and elderly of São Paulo

Selem, Soraya Sant'Ana de Castro
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 03/05/2012 PT
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Introdução: A hipertensão, doença cardiovascular de alta prevalência, tem influência relevante na morbi-mortalidade da população, e a dieta é um de seus principais fatores de risco modificáveis. Objetivos: Verificar a validade da hipertensão auto-referida e a associação entre os padrões da dieta e a hipertensão auto-referida em residentes do município de São Paulo. Métodos: Foram utilizados dados do estudo transversal de base populacional ISA - Capital 2008, referentes à amostra probabilística de residentes do município de São Paulo com 20 anos ou mais, de ambos os sexos. A coleta de dados ocorreu em 2008 e 2010, por meio de duas visitas domiciliares e inquérito telefônico. Foram coletados dados socioeconômicos, antropométricos, de estilo de vida, inquérito alimentar, e a pressão arterial foi aferida. A validade da hipertensão auto-referida foi verificada pela sensibilidade, especificidade, valor preditivo positivo (VPP), valor preditivo negativo (VPN) e coeficiente kappa. Estimou-se o consumo alimentar por dois recordatórios de 24 horas, ajustando-se a variabilidade pelo Multiple Source Method. Os padrões da dieta foram obtidos pela análise fatorial por componentes principais. A regressão de Poisson foi utilizada para verificar as associações. Resultados: A sensibilidade da hipertensão auto-referida foi 71...

Prevalência da hipertensão arterial, avaliada pela medida casual e monitorização residencial da pressão arterial, em comunidades adventistas do sétimo dia no sudoeste paulista; Arterial hypertension prevalence, assessed through casual measurement and home blood pressure monitoring, in Seventh Day Adventist communities in Southeastern São Paulo

Silva, Stael Silvana Bagno Eleuterio da
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 25/09/2012 PT
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Introdução A hipertensão arterial é influenciada por hábitos e estilos de vida e populações específicas como os Adventistas o Sétimo Dia são orientados a incorporar em suas práticas religiosas, hábitos e estilos de vida saudáveis. O objetivo principal desse estudo foi comparar a prevalência da hipertensão arterial em comunidades Adventistas do Sétimo Dia com comunidade não Adventista. Casuística e Métodos O estudo foi realizado na região sudoeste do estado de São Paulo com 547 pessoas (304 Adventistas e 243 não Adventistas). A pressão arterial foi medida com aparelho automático validado e de acordo com as VI Diretrizes Brasileiras de Hipertensão. A religiosidade foi avaliada pela Escala de Duke-DUREL; hábitos alimentares identificados pelo Questionário de Frequência Alimentar; apoio social pela escala de apoio social; consumo de bebida alcoólica pelo Alcohol Use Disorders Identification Test AUDIT e transtornos mentais comuns pelo Self-Reporting Questionnaire (SRQ 20). Foi adotado nível de significância de p<0,05. Resultados A maioria era do sexo feminino, idade de 41,5 anos, etnia branca. A prevalência de hipertensão foi menor nos Adventistas (p<0,05, 25,6% vs 35,4%). Os Adventistas foram diferentes (p<0...

Prevalência de hipertensão resistente em adultos não idosos : estudo prospectivo em contexto ambulatorial; Prevalence of resistant hypertension in non-elderly adults: prospective study in a clinical setting

Massierer, Daniela; Oliveira, Ana Claudia Tonelli de; Steinhorst, Ana Maria Pasquali; Gus, Miguel; Ascoli, Aline Maria; Gonçalves, Sandro Cadaval; Moreira, Leila Beltrami; Correa Junior, Vicente; Nunes, Gerson Luis da Silva; Fuchs, Sandra Cristina Pereir
Fonte: Universidade Federal do Rio Grande do Sul Publicador: Universidade Federal do Rio Grande do Sul
Tipo: Artigo de Revista Científica Formato: application/pdf
POR
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36.61%
Fundamento: Em face do emprego de diferentes definições e critérios de amostragem, a real prevalência de hipertensão resistente em ambiente clínico é desconhecida. Objetivo: Investigar a prevalência de real hipertensão resistente em uma clínica de hipertensão arterial. Métodos: Hipertensão resistente verdadeira foi diagnosticada quando fenômeno do jaleco branco, insuficiente adesão ao tratamento e hipertensão secundária foram excluídos em pacientes com Pressão Arterial (PA) ≥ 140/90 mmHg em duas visitas consecutivas, usando três de fármacos anti-hipertensivos, incluindo um diurético. Resultados: No total, 606 pacientes, com 35 a 65 anos de idade, a maioria mulheres, com PA de 156,8 ± 23,8 mmHg por 91,9 ± 15,6 mmHg e IMC de 29,7 ± 5,9 Kg/m2 foram sequencialmente avaliados. Cento e seis pacientes em uso de três agentes anti-hipertensivos estavam com pressão arterial não controlada (17,5% da amostra total) na primeira visita. Oitenta e seis pacientes (81% dos pacientes com PA não controlada na primeira avaliação) retornaram para a avaliação de confirmação: 25 estavam com PA controlada; 21 tinham evidência de baixa adesão ao tratamento; 13 tinham fenômeno do jaleco branco; e 9 tinham hipertensão secundária...

Prevention of hypertension in patients with pre-hypertension: Protocol for the PREVER-prevention trial

Fuchs, Flávio D.; Fuchs, Sandra C.; Moreira, Leila B.; Gus, Miguel; Nóbrega, Antônio C.; Poli-de-Figueiredo, Carlos E.; Mion, Décio; Bortoloto, Luiz; Consolim-Colombo, Fernanda; Nobre, Fernando; Coelho, Eduardo B.; Vilela-Martin, José F.; Moreno Jr,
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
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Background: Blood pressure (BP) within pre-hypertensive levels confers higher cardiovascular risk and is an intermediate stage for full hypertension, which develops in an annual rate of 7 out of 100 individuals with 40 to 50 years of age. Non-drug interventions to prevent hypertension have had low effectiveness. In individuals with previous cardiovascular disease or diabetes, the use of BP-lowering agents reduces the incidence of major cardiovascular events. In the absence of higher baseline risk, the use of BP agents reduces the incidence of hypertension. The PREVER-prevention trial aims to investigate the efficacy, safety and feasibility of a population-based intervention to prevent the incidence of hypertension and the development of target-organ damage.Methods: This is a randomized, double-blind, placebo-controlled clinical trial, with participants aged 30 to 70 years, with pre-hypertension. The trial arms will be chlorthalidone 12.5 mg plus amiloride 2.5 mg or identical placebo. The primary outcomes will be the incidence of hypertension, adverse events and development or worsening of microalbuminuria and of left ventricular hypertrophy in the EKG. The secondary outcomes will be fatal or non-fatal cardiovascular events: myocardial infarction...

Exaggerated blood pressure response during the exercise treadmill test as a risk factor for hypertension

Lima,S.G.; Albuquerque,M.F.P.M.; Oliveira,J.R.M.; Ayres,C.F.J.; Cunha,J.E.G.; Oliveira,D.F.; Lemos,R.R.; Souza,M.B.R.; Silva,O. Barbosa e
Fonte: Associação Brasileira de Divulgação Científica Publicador: Associação Brasileira de Divulgação Científica
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/04/2013 EN
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Exaggerated blood pressure response (EBPR) during the exercise treadmill test (ETT) has been considered to be a risk factor for hypertension. The relationship of polymorphisms of the renin-angiotensin system gene with hypertension has not been established. Our objective was to evaluate whether EBPR during exercise is a clinical marker for hypertension. The study concerned a historical cohort of normotensive individuals. The exposed individuals were those who presented EBPR. At the end of the observation period (41.7 months = 3.5 years), the development of hypertension was analyzed within the two groups. Genetic polymorphisms and blood pressure behavior were assessed as independent variables, together with the classical risk factors for hypertension. The I/D gene polymorphism of the angiotensin-converting enzyme and M235T of angiotensinogen were ruled out as risk factors for hypertension. EBPR during ETT is not an independent influence on the chances of developing hypertension. No differences were observed between the hypertensive and normotensive individuals regarding gender (P = 0.655), skin color (P = 0.636), family history of hypertension (P = 0.225), diabetes mellitus (P = 0.285), or hypertriglyceridemia (P = 0.734). The risk of developing hypertension increased with increasing body mass index (BMI) and advancing age. The risk factors...

Public education on hypertension: A new initiative to improve the prevention, treatment and control of hypertension in Canada

Campbell, Norman R; Petrella, Robert; Kaczorowski, Janusz
Fonte: Pulsus Group Inc Publicador: Pulsus Group Inc
Tipo: Artigo de Revista Científica
Publicado em /05/2006 EN
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High blood pressure is one of the leading risk factors for death. Nevertheless, there is a lack of awareness of hypertension as a risk factor, as well as significant misconceptions about hypertension in the Canadian population. Furthermore, according to the Canadian Heart Health Surveys (1985 to 1992), 42% of hypertensive adult Canadians are unaware of their hypertensive status. A collaboration between Blood Pressure Canada, the Heart and Stroke Foundation of Canada, the Canadian Hypertension Society and the Canadian Hypertension Education Program has been formed to improve public and patient awareness and knowledge of hypertension. The effort will involve the translation of Canadian Hypertension Education Program recommendations for the prevention and management of hypertension to a public level with a broad and evolving dissemination strategy; the training of health professionals to speak to the public and patients on hypertension, coupled with opportunities to speak in forums organized in their local communities; and, media releases and information on hypertension in association with World Hypertension Day and the release of the annually updated public recommendations. Based on higher rates of awareness of hypertension in countries with sustained public education programs on hypertension...

Risk factors for hypertension during pregnancy in South Australia

Jacobs, D.; Vreeburg, S.; Dekker, G.; Heard, A.; Priest, K.; Chan, A.
Fonte: Australian NZ J Obstet Gynaec Publicador: Australian NZ J Obstet Gynaec
Tipo: Artigo de Revista Científica
Publicado em //2003 EN
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36.6%
Objective: To identify risk factors for hypertension in pregnancy among South Australian women. Design: A population-based retrospective analysis using the South Australian perinatal data collection for 1998–2001. Methods: Three groups of women with hypertension (pre-existing hypertension, pregnancy hypertension, and superimposed pre-eclampsia) were compared with normotensive women using unconditional logistic regression analysis on 70 386 singleton births to identify sociodemographic and clinical risk factors for hypertension in pregnancy. Results: Nulliparity, Aboriginal race and Caucasian race (compared with Asian) and pre-existing and gestational diabetes were demonstrated to be risk factors for all hypertensive disorders, as was increasing maternal age for pre-existing hypertension and superimposed pre-eclampsia. Risk was increased for pregnancy hypertension and superimposed pre-eclampsia among women who gave their occupation as ‘home duties’ and also for superimposed pre-eclampsia among unemployed women. Women with hypertension were more likely to give birth in teaching hospitals. Urinary tract infections were not found to be a risk factor for any type of hypertension. Smoking during pregnancy was protective for all types of hypertension. Conclusions: The present study used a statewide population perinatal database and has confirmed that Aboriginal race...

Vergleich schnittbildmorphologischer und klinischer Stigmata portaler Hypertension und Leberzirrhose bei Patienten mit Anlage eines Transjugulären Intrahepatischen Portosystemischen Shunts (TIPSS); Comparison of signs of portal hypertension in imaging data (CT-scans and MRI) and clinical manifestations of portal hypertension in patients who underwent transjugular intrahepatic portosystemic shunt (TIPS) placement

Batsching, Katharina Frederike
Fonte: Universidade de Tubinga Publicador: Universidade de Tubinga
Tipo: Dissertação
DE_DE
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36.63%
Portale Hypertension ist eine häufige Folge zahlreicher Lebererkrankungen und kann mit schwerwiegenden Komplikationen einhergehen. Die Standardmethode zur Evaluation des portosystemischen Druckgradienten ist die invasive, blutige Druckmessung. Zusätzlich gibt es Ansätze, den portosystemischen Druckgradienten noninvasiv abzuschätzen, da die invasive Messung nicht überall verfügbar ist und Riskiken birgt. Zur Zeit sind die Methoden zur noninvasiven Druckgradientenabschätzung der invasiven Messung unterlegen. Diese Arbeit beschäftigt sich mit Zusammenhängen zwischen bildmorphologischen, klinischen und laborchemischen Stigmata portaler Hypertension und dem portosystemischen Druckgradienten vor und nach einer Anlage eines Transjugulären Intrahepatischen Portosystemischen Shunts (TIPSS). Ziel war, Erkenntnisse herauszuarbeiten, die weiteren Ansätzen der noninvasiven Abschätzung des portosystemischen Druckgradienten zugute kommen können. In diese Studie wurden die Daten von Patienten in die Studie eingeschlossen, welche zwischen Januar 2002 und August 2008 eine Anlage eines TIPSS erhielten, der portosystemische Druckgradient prä- und postinterventionell dokumentiert wurde und bei welchen eine präinterventionelle Computertomographie oder Magnetresonanztomographie des Abdomens vorlag. Insgesamt 70 Patienten erfüllten die Einschlusskriterien. Zusätzlich zu den erhobenen bildmorphologischen Charakteristika wurden retrospektiv klinische und laborchemische Daten...

Self-reported knowledge and awareness about blood pressure and hypertension: a cross-sectional study of a random sample of men and women aged 60-74 years

Qvist, I.; Thomsen, M.D.; Lindholt, J.S.; Ibsen, H.; Hendriks, J.M.L.; Frost, L.
Fonte: Dove Medical Press Publicador: Dove Medical Press
Tipo: Artigo de Revista Científica
Publicado em //2014 EN
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36.61%
BACKGROUND: In general, it is assumed that patient education, by increasing knowledge, may change behavior and lifestyle and promote health. In this context, it is a surprise that knowledge and awareness about blood pressure and hypertension among elderly people is poor. We hypothesized that knowledge about blood pressure and hypertension would be better among individuals with self-reported hypertension compared with subjects without self-reported hypertension. METHODS: We mailed a questionnaire to a random sample of 1,000 subjects living in the municipality of Silkeborg, Denmark. The study sample was drawn from the Central Person Registry. RESULTS: The response rate was 72%. Of these, 43% of responders had self-reported hypertension. The people with self-reported hypertension were older, less educated, had higher self-reported blood cholesterol levels, had higher body weight, and more often had a family history of hypertension. More than 80% reported that overweight and obesity increases blood pressure. More than 60% reported that untreated hypertension may cause heart disease or stroke. More than half of the responders did not know their blood pressure, and only 21% knew that hypertension can occur without symptoms. Knowledge about hypertension was independent of self-reported hypertension status...

Hypertension artérielle dans la population adulte du Burkina Faso : prévalence, détection, traitement et contrôle

Doulougou, Boukaré
Fonte: Université de Montréal Publicador: Université de Montréal
Tipo: Thèse ou Mémoire numérique / Electronic Thesis or Dissertation
FR
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Contexte : L’hypertension artérielle (HTA) est reconnue comme un important facteur de risque des maladies cardiovasculaires et de la mortalité prématurée. Les données montrent qu’un adulte sur 4 dans le monde souffrait d’hypertension en 2000 et ce chiffre serait en augmentation. Dans les pays africains, les estimations prévoient une progression plus rapide de la prévalence de l’HTA engendrant ainsi un problème additionnel à gérer pour le système de santé qui est toujours aux prises avec les maladies transmissibles. Les progrès économiques et l’urbanisation semblent entraîner des modifications des habitudes de vie dans ces pays qui seraient associés à une émergence des maladies non transmissibles, dont l’HTA. Le Burkina Faso, pays de l’Afrique de l’Ouest classé comme un pays à faibles revenus, aurait amorcé sa transition épidémiologique et il importe de faire un état sur les maladies non transmissibles en émergence. Afin de contribuer à la connaissance des aspects épidémiologiques de l’HTA au Burkina Faso, trois objectifs spécifiques ont été retenus pour la présente recherche : 1) Estimer la prévalence de l’HTA et identifier les facteurs associés dans la population rurale et la population semi-urbaine du Système de Surveillance démographique et de Santé de Kaya (Kaya HDSS) ; 2) Déterminer la différence de prévalence de l’HTA entre la zone lotie et la zone non lotie de la ville de Ouagadougou et identifier les facteurs associés ; 3) Déterminer la détection...

Prevalência de obesidade e hipertensão arterial e associação com fatores de risco em escolares da cidade de Sorocaba, São Paulo, Brasil; Obesity and arterial hypertension prevalence and their association with risk factors in schoolchildren from Sorocaba city, São Paulo, Brazil

Isabela Annunziato Ramos Mazaro
Fonte: Biblioteca Digital da Unicamp Publicador: Biblioteca Digital da Unicamp
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 02/06/2011 PT
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INTRODUÇÃO: Nas últimas décadas houve aumento significativo da prevalência da obesidade e de suas complicações na faixa etária pediátrica, incluindo a hipertensão arterial. OBJETIVO: Estimar a prevalência da obesidade e da hipertensão arterial e da associação destas com fatores de risco em estudantes de Sorocaba (SP). MÉTODO: Estudo transversal, de base populacional fixa e amostra aleatória com observação individual de 680 alunos de 7 a 11 anos. Foram avaliados: sexo, idade, região de moradia, classificação econômica, antecedentes pessoais, maternos e paternos para hipertensão arterial, doença renal e cardíaca, realização de atividade física fora da escola, tempo com TV/VG/PC. Foram realizadas medidas de: peso, altura, circunferência da cintura, dobras cutâneas, PA e verificado a presença de acanthosis nigricans. Calculou-se a prevalência de sobrepeso, obesidade e excesso de peso; pré-hipertensão, hipertensão arterial e de PA elevada. Para associação destes com as demais variáveis empregou-se o teste do qui-quadrado ou o Exato de Fisher (p<0,05). Determinou-se a razão de chances prevalente bruta e ajustada por regressão logística. RESULTADOS: Do total: 49% eram do sexo masculino, sendo, 19% com 7 anos; 23...

High blood pressure six weeks postpartum after hypertensive pregnancy disorders at term is associated with chronic hypertension

Visser, V.; Hermes, W.; Franx, A.; Koopmans, C.; van Pampus, M.; Mol, B.; de Groot, C.
Fonte: Elsevier BV Publicador: Elsevier BV
Tipo: Artigo de Revista Científica
Publicado em //2013 EN
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36.61%
OBJECTIVES: Hypertension in pregnancy is associated with cardiovascular disease (CVD) later in life. Blood pressure monitoring in women who experienced hypertension in pregnancy after puerperium has been suggested to be important for early detection and prevention of CVD. The aim of this study is to evaluate if hypertension six weeks postpartum is associated with chronic hypertension in women with a history of term hypertensive pregnancy disorders. STUDY DESIGN: Women with a history of term gestational hypertension or preeclampsia were included in a follow up study of the HYPITAT trial. Blood pressures were measured six weeks and 2.5years postpartum according to the study protocol. MAIN OUTCOME MEASURES: Hypertension was defined as a diastolic blood pressure ⩾90mmHg and/or a systolic blood pressure ⩾140mmHg or use of antihypertensive medication. Differences in categorical variables between groups were analyzed by Chi-Square tests. Blood pressure was analyzed using unpaired t-tests and Wilcox ranked tests. RESULTS: Among 187 women who had term hypertensive pregnancy disorders, 75 (40%) had hypertension at six weeks postpartum. Of these 46 (61%) had hypertension 2.5years postpartum. In contrast, of 112 women without hypertension at six weeks postpartum...

Self-Screening and Non-Physician Screening for Hypertension in Communities: A Systematic Review

Fleming, Susannah; Atherton, Helen; McCartney, David; Hodgkinson, James; Greenfield, Sheila; Hobbs, Frederick David Richard; Mant, Jonathan; McManus, Richard J.; Thompson, Matthew; Ward, Alison; Heneghan, Carl
Fonte: Oxford Journals on behalf of American Journal of Hypertension, Ltd. Publicador: Oxford Journals on behalf of American Journal of Hypertension, Ltd.
Tipo: Article; published version
EN
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This is the final version of the article. It was first available from Oxford University Press via http://dx.doi.org/10.1093/ajh/hpv029; Background Community-based self-screening may provide opportunities to increase detection of hypertension, and identify raised blood pressure (BP) in populations who do not access healthcare. This systematic review aimed to evaluate the effectiveness of non-physician screening and self-screening of BP in community settings. METHODS We searched the Cochrane Central Trials Register, Medline, Embase, CINAHL, and Science Citation Index & Conference Proceedings Citation Index?Science to November 2013 to identify studies reporting community- based self-screening or non-physician screening for hypertension in adults. Results were stratified by study site, screener, and the cut-off used to define high screening BP. RESULTS We included 73 studies, which described screening in 9 settings, with pharmacies (22%) and public areas/retail (15%) most commonly described. We found high levels of heterogeneity in all analyses, despite stratification. The highest proportions of eligible participants screened were achieved by mobile units (range 21%?88%) and pharmacies (range 40%?90%). Self-screeners had similar median rates of high BP detection (25%?35%) to participants in studies using other screeners. Few (16%) studies reported referral to primary care after screening. However...

Lipopolysaccharide Reverses Adrenocorticotrophic Hormone-Induced Hypertension in the Rat

Zhang, Yi; Schyvens, Chris; McKenzie, Katja; Morris, Brian; Whitworth, Judith
Fonte: Japanese Society for Hypertension Publicador: Japanese Society for Hypertension
Tipo: Artigo de Revista Científica
Relevância na Pesquisa
46.44%
Lipopolysaccharide (LPS) was used to stimulate nitric oxide (NO) release and investigate the effect of endogenous NO on adrenocorticotrophic hormone (ACTH)-induced hypertension in rats. After preliminary studies to determine the appropriate dose of LPS, 40 male Sprague-Dawley rats were treated with ACTH (200 μg/kg/day, s.c.) or saline (sham) for 8 days and then given a single dose of LPS (10 mg/kg, i.p.) or saline. ACTH treatment was continued for a further 5 days. Systolic blood pressure (SBP) was measured daily using the tail cuff method. Results were expressed as the mean±SEM. ACTH treatment significantly increased SBP (from 105±3 to 129±4 mmHg; p<0.05), whereas saline had no effect on SBP. The ACTH-induced increase in SBP was reversed by LPS injection (from 125±6 to 102±7 mmHg; p<0.05). SBP was also decreased in sham + LPS-treated rats compared with that of sham + saline-treated rats (p<0.05), but the SBP change in response to LPS was greater in ACTH-treated than in sham-treated rats (-23 vs. -8 mmHg; p<0.05). These data are compatible with the notion that reduced NO availability plays a role in ACTH-induced hypertension.

Patterns of left ventricular remodeling among patients with essential and secondary hypertension

Radulescu,Dan; Stoicescu,Laurentiu; Buzdugan,Elena; Donca,Valer
Fonte: Sociedad Médica de Santiago Publicador: Sociedad Médica de Santiago
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2013 EN
Relevância na Pesquisa
36.61%
Background: High blood pressure causes left ventricular hypertrophy, which is a negative prognostic factor among hypertensive patients. Aim: To assess left ventricular geometric remodeling patterns in patients with essential hypertension or with hypertension secondary to parenchymal renal disease. Material and Methods: We analyzed data from echocardiograms performed in 250patients with essential hypertension (150 females) and 100 patients with secondary hypertension (60 females). The interventricular septum and the left ventricular posterior wall thickness were measured in the parasternal long-axis. Left ventricular mass was calculated using the Devereaux formula. Results: The most common remodeling type in females and males with essential hypertension were eccentric and concentric left ventricular hypertrophy (cLVH), respectively. Among patients with secondary arterial hypertension, cLVH was most commonly observed in both genders. The prevalence of left ventricular hypertrophy was higher among patients with secondary hypertension. The left ventricular mass index and the relative left ventricular wall thickness were higher in males and also in the secondary hypertension group. Age, blood pressure values and the duration of hypertension...

Blood pressure control, hypertension, awareness, and treatment in adults with diabetes in the United States-Mexico border region

Vijayaraghavan,Maya; He,Guozhong; Stoddard,Pamela; Schillinger,Dean
Fonte: Organización Panamericana de la Salud Publicador: Organización Panamericana de la Salud
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/09/2010 EN
Relevância na Pesquisa
36.59%
OBJETIVE: To determine prevalence of blood pressure control, hypertension, hypertension awareness, and antihypertensive treatment among adults (> 18 years old) with diabetes living in the border region between the United States of America and Mexico, and to explore variation in those variables between all adults on the Mexican side of the border ("Mexicans") and three groups on the U.S. side of the border ("all U.S. adults," "U.S.-born Hispanics," and "Mexican immigrants"). METHODS: Using data from Phase I (February 2001-October 2002) of the U.S.-Mexico Border Diabetes Prevention and Control Project, a prevalence study of type 2 diabetes and its risk factors, age-adjusted prevalence of hypertension-related variables was calculated for the sample (n = 682) and differences between the border groups were examined through logistic regression. RESULTS: Less than one-third of the sample had controlled blood pressure (< 130/80 mm Hg), almost half had hypertension (>140/90 mm Hg), and hypertension awareness and treatment were inadequate. After adjusting for demographics, body mass index, and access to health care, there were no differences in blood pressure control, hypertension, hypertension awareness, or treatment between Mexicans and both U.S. adults and Mexican immigrants. However...