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Growth of very low birth weight infants fed with milk from a human milk bank selected according to the caloric and protein value

APRILE, Marisa Matta; FEFERBAUM, Rubens; ANDREASSA, Nerli; LEONE, Claudio
Fonte: Faculdade de Medicina / USP Publicador: Faculdade de Medicina / USP
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
66.23%
OBJECTIVE: To describe growth and clinical evolution of very low birth weight infants fed during hospital stay with milk from a human milk bank according to the caloric-protein value. METHOD: Forty very low birth weight infants were included: 10 were fed milk from their own mothers (GI), and 30 were fed human milk bank > 700 cal/L and 2 g/dL of protein. Growth curves were adjusted using nonlinear regression to the measured growth parameters. RESULTS: full enteral diet was reached in 6.3 days by GI and in 10.8 by GII; a weight of 2 kg was reached in 7.3 weeks for GI and in 7.8 for GII. In GI, 3/10 (33.3%) and in GII, 7/30 (23.3%) developed sepsis. Necrotizing enterocolitis did not occur in GI, but in 3/30 (10.0%) in GII. GI presented with urinary calcium > 4 mg/L in 1/10 (10.0%), urinary phosphorus (Pu) <1 mg/L in 10/10 (100%), and Ca/Cr >0.6 ratio in 1/10 (10.0%) of the cases; in GII, no children presented alterations of the urinary calcium or the Ca and Cr ratio, and Pu was <1 mg/L in 19/30 (63.3%). In terms of growth the 50th percentile for GI was a weight gain of 12.1 g/day (GI) vs. 15.8 g/day (GII), a length gain of 0.75 cm/week (GI) vs. 1.02 cm/week (GII), and a head circumference gain of 0.74 cm/week (GI) vs. 0.76 cm/week (GII). CONCLUSIONS: Human milk bank allowed a satisfactory growth and good clinical evolution for very low birth weight infants.

Hepatitis B viral markers in banked human milk before and after Holder pasteurization

OLIVEIRA, Patricia Ribeiro de; YAMAMOTO, Aparecida Yulie; SOUZA, Cleonice Barbosa Sandoval de; ARAUJO, Natalia Motta de; GOMES, Selma de Andrade; HECK, Analia Ribeiro; FIGUEIREDO, Jose Fernando de Castro; MUSSI-PINHATA, Marisa Marcia
Fonte: ELSEVIER SCIENCE BV Publicador: ELSEVIER SCIENCE BV
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
66.25%
Background: Blood screening for hepatitis B virus (HBV) is not universally performed for donor selection in human milk banks. Objectives: To evaluate the frequency of detection of HBV surface antigen (HBsAg) and HBV-DNA in colostrum of HBV-infected nursing mothers before and after Holder pasteurization. Study design: Forty-two concentrated breast milk samples were obtained within two postnatal weeks from 24 HBsAg-positive women (4 HBeAg-positive and 20 HBeAg-negative, anti-HBe-positive) were tested for the presence of HBsAg and HBV-DNA before and after Holder pasteurization (30 min at 62.5 degrees C). Results: Before pasteurization, HBsAg and HBV-DNA were found in 14/24 (58%), and 20/24 (75%) first milk samples, respectively, obtained by 4 days after delivery. At least one marker was detected in 20/24 (83%) milk samples. Both markers were identified in milk of HBeAg-positive mothers, and most mothers with anti-HBe in blood had at least one HBV marker. Once detected, viral markers were frequently found in milk samples subsequently obtained from the same woman. Holder pasteurization did not affect the probability of detecting HBsAg (8/18, 44%), HBV-DNA (12/18, 67%). or at least one of them (15118, 83%). Conclusions: Although the biological implications of these findings remain to be determined...

Iron Concentrations in Breast Milk and Selected Maternal Factors of Human Milk Bank Donors

MELLO-NETO, Julio; RONDO, Patricia H. C.; MORGANO, Marcelo A.; OSHIIWA, Marie; SANTOS, Mariana L.; OLIVEIRA, Julicristie M.
Fonte: SAGE PUBLICATIONS INC Publicador: SAGE PUBLICATIONS INC
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
66.24%
The aim of this study was to evaluate the relationship between iron concentration in mature breast milk and characteristics of 136 donors of a Brazilian milk bank. Iron, vitamin A, zinc, and copper concentrations were assessed in human milk and maternal blood. Data were collected on maternal anthropometrics, obstetric, socioeconomic, demographic, and lifestyle factors. Iron, zinc, and copper in milk and zinc and copper in blood were detected by spectrophotometry. Vitamin A in milk and blood was determined by high-performance liquid chromatography. Hemoglobin was measured by electronic counting and serum iron and ferritin by colorimetry and chemoluminescence, respectively. Transferrin and ceruloplasmin were determined by nephelometry. According to multivariate linear regression analysis, iron in milk was positively associated with vitamin A in milk and with smoking but negatively associated with timing of breast milk donation (P < .001). These results indicate that iron concentration in milk of Brazilian donors may be influenced by nutritional factors and smoking. J Hum Lact. 26(2):175-179

Síntese de lipídios estruturados por interesterificação de banha e óleo de soja para obtenção de sucedâneo da gordura do leite humano; Synthesis of structure lipids by interesterification of lard and soybean oil for obtain human milk fat substitute

Silva, Roberta Claro da
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 14/03/2008 PT
Relevância na Pesquisa
66.25%
O leite humano é um alimento completo, possui todos os nutrientes em quantidade e qualidade necessárias, proporciona proteção contra infecções e alergias e estimula o sistema imunológico. Os lipídios do leite humano são fonte energética; veículos para as vitaminas lipossolúveis; contêm ácidos graxos poliinsaturados necessários para o desenvolvimento cerebral; contêm precursores de prostaglandinas e hormônios; e são constituintes essenciais para as membranas celulares. Muitas mães, por razões médicas, metabólicas ou econômicas, dependem de fórmulas artificiais para alimentar seus filhos. Portanto, a composição dos ácidos graxos e a sua distribuição nas cadeias dos triacilgliceróis devem ser alvos de estudos em fórmulas infantis, sendo que os triacilgliceróis do leite humano devem servir de modelo para os componentes lipídicos. Recentemente, diversos estudos apontam a interesterificação como alternativa para a produção de sucedâneos da gordura do leite humano. Assim, o objetivo deste trabalho foi explorar diversas possibilidades da modificação lipídica para a obtenção deste sucedâneo. As matérias-primas utilizadas foram banha e óleo de soja, gorduras facilmente obtidas e de baixo custo no Brasil. Neste trabalho...

Efeitos do uso de aditivo no leite humano cru da própria mãe em recém-nascidos pré-termo de muito baixo peso; Effects of the use of additive in the raw human milk of mothers of very low birth weight preterm newborns

Martins, Evelyn Conti
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 01/12/2008 PT
Relevância na Pesquisa
66.26%
A nutrição do recém-nascido pré-termo de muito baixo peso representa um desafio para a equipe multiprofissional devido a condições especiais, como o metabolismo acelerado, diminuição das reservas orgânicas, maior risco de complicações associadas à imaturidade do sistema digestivo e a capacidade reduzida de adaptação frente a situações de sobrecarga hidro-eletrolítica. A preocupação com a nutrição do pré-termo justifica-se pela necessidade de promover velocidade de crescimento físico e desenvolvimento semelhantes à da vida intra-uterina. Objetivos: a) Geral; comparar o ganho ponderoestatural e a freqüência de complicações clínicas em recém-nascidos prétermo com peso inferior a 1500g, alimentados exclusivamente com leite humano cru da própria mãe, com e sem a suplementação de aditivo, até atingirem o peso de 1800g; b)Específicos: descrever e comparar o ganho pondero-estatural e a freqüência de complicações clínicas em recém-nascidos pré-termo com peso inferior a 1500g, alimentados exclusivamente com leite humano cru da própria mãe, com e sem a suplementação de aditivo, até atingirem o peso de 1800g. Métodos: Ensaio clínico prospectivo randomizado duplo-cego em 40 recém-nascidos pré-termo com peso de nascimento inferior a 1500g internados em unidade de terapia intensiva neonatal no período de agosto de 2005 a abril de 2007. Para detectar a diferença de 3...

Leite humano como fonte de bactérias lácticas produtoras de bacteriocinas e com potencial probiótico; Human milk as a source of lactic acid bacteria producing bacteriocins and probiotic potential

Trento, Fabiana Katia Helena de Souza
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 14/09/2012 PT
Relevância na Pesquisa
66.28%
Além do aspecto nutricional de suma importância, é notória a contribuição do leite humano para o processo de desenvolvimento da microbiota intestinal do recémnascido, um importante mecanismo de defesa do organismo contra doenças infecciosas. O papel do leite humano como fonte de bactérias probióticas, principais constituintes da microbiota intestinal, tem sido tópico de pesquisas recentes. Este trabalho foi desenvolvido com o objetivo de determinar e comparar a composição da microbiota de oito amostras de leite humano e verificar o potencial de utilização desse produto como fonte de bactérias probióticas. Para tanto, utilizaram-se cinco meios de cultivos seletivos para contagem presuntiva de gêneros normalmente encontrados em leite humano: lactococos, enterococos, bifidobactérias e propionibactérias. A análise quantitativa da microbiota demonstrou tendência de diminuição da contagem em função do aumento do tempo de lactação. A análise qualitativa confirmou a presença de distintos gêneros de bactérias lácticas potencialmente probióticas com algumas variações entre as amostras de leite humano. Na segunda etapa 800 colônias isoladas a partir dos cinco meios de cultivos e caracterizadas como bactérias lácticas foram selecionadas quanto às suas propriedades probióticas (produção de bacteriocina...

Vitamin E concentration in human milk and associated factors: a literature review,

Lima,Mayara S.R.; Dimenstein,Roberto; Ribeiro,Karla D.S.
Fonte: Sociedade Brasileira de Pediatria Publicador: Sociedade Brasileira de Pediatria
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/10/2014 EN
Relevância na Pesquisa
66.24%
^a Objective: To systematize information about vitamin E concentration in human milk and the variables associated with this composition in order to find possible causes of deficiency, supporting strategies to prevent it in postpartum women and infants. Source: Studies published between 2004 and 2014 that assayed alpha-tocopherol in human milk of healthy women by high performance liquid chromatography were evaluated. The keywords used were "vitamin E", "alpha-tocopherol", "milk, human", "lactation", and equivalents in Portuguese, in the BIREME, CAPES, PubMed, SciELO, ISI Web of Knowledge, HighWire Press, Ingenta, and Brazilian Digital Library of Theses and Dissertations databases. Summary of the findings: Of the 41 publications found on the subject, 25 whose full text was available and met the inclusion criteria were selected. The alpha-tocopherol concentrations found in milk were similar in most populations studied. The variable phase of lactation was shown to influence vitamin E content in milk, which is reduced until the mature milk appears. Maternal variables parity, anthropometric nutritional status, socioeconomic status, and habitual dietary intake did not appear to affect the alpha-tocopherol levels in milk. However, the influence of the variables maternal age...

Homologous human milk supplement for very low birth weight preterm infant feeding

Grance,Thayana Regina de Souza; Serafin,Paula de Oliveira; Thomaz,Débora Marchetti Chaves; Palhares,Durval Batista
Fonte: Sociedade de Pediatria de São Paulo Publicador: Sociedade de Pediatria de São Paulo
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/03/2015 EN
Relevância na Pesquisa
66.24%
OBJECTIVE: To develop a homologous human milk supplement for very low-birth weight infant feeding, using an original and simplified methodology, to know the nutritional composition of human milk fortified with this supplement and to evaluate its suitability for feeding these infants. METHODS: For the production and analysis of human milk with the homologous additive, 25 human milk samples of 45mL underwent a lactose removal process, lyophilization and then were diluted in 50mL of human milk. Measurements of lactose, proteins, lipids, energy, sodium, potassium, calcium, phosphorus and osmolality were performed. RESULTS: The composition of the supplemented milk was: lactose 9.22±1.00g/dL; proteins 2.20±0.36g/dL; lipids 2.91±0.57g/dL; calories 71.93±8.69kcal/dL; osmolality 389.6±32.4mOsmol/kgH2O; sodium 2.04±0.45mEq/dL; potassium 1.42±0.15mEq/dL; calcium 43.44±2.98mg/dL; and phosphorus 23.69±1.24mg/dL. CONCLUSIONS: According to the nutritional contents analyzed, except for calcium and phosphorus, human milk with the proposed supplement can meet the nutritional needs of the very low-birth weight preterm infant.

Inhibition of enterotoxigenic Escherichia coli (ETEC) adhesion to Caco-2 cells by human milk and its immunoglobulin and non-immunoglobulin fractions

Oliveira,Inaiara R. de; Bessler,Heidi C.; Bao,Sonia N.; Lima,Renato de L.; Giugliano,Loreny G.
Fonte: Sociedade Brasileira de Microbiologia Publicador: Sociedade Brasileira de Microbiologia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/03/2007 EN
Relevância na Pesquisa
66.21%
Enterotoxigenic Escherichia coli (ETEC) is the most common cause of diarrhea in children in developing countries and among travelers to ETEC endemic areas. ETEC diarrhea is caused by colonization of the small intestine mediated by colonization factor (CF) antigens, and subsequent elaboration of enterotoxins. Breast feeding has been related to protection against enteric infections. The protective effect of human milk can be ascribed to its immunoglobulin content, specially secretory immunoglobulin A (sIgA), and to non-immunoglobulin components such as free oligosaccharides, glycoproteins and glycolipids. In this study we investigated the effect of whole human milk and its fractions immunoglobulin and non-immunoglobulin on the adherence of ETEC strains possessing different CFs to Caco-2 cells, as well as the ability of sIgA and free secretory component (fSC) to bind to bacterial superficial proteins. Pooled human milk from three donors were fractionated by gel filtration and analyzed by SDS-PAGE. Our results revealed that whole human milk and its proteins fractions, containing sIgA and fSC, inhibited adhesion ETEC strains harboring different colonization factors antigens. We also verified that sIgA and fSC, using immunoblotting and immunogold labeling assays...

Growth of very low birth weight infants fed with milk from a human milk bank selected according to the caloric and protein value

Aprile,Marisa Matta; Feferbaum,Rubens; Andreassa,Nerli; Leone,Claudio
Fonte: Faculdade de Medicina / USP Publicador: Faculdade de Medicina / USP
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/2010 EN
Relevância na Pesquisa
66.23%
OBJECTIVE: To describe growth and clinical evolution of very low birth weight infants fed during hospital stay with milk from a human milk bank according to the caloric-protein value. METHOD: Forty very low birth weight infants were included: 10 were fed milk from their own mothers (GI), and 30 were fed human milk bank > 700 cal/L and 2 g/dL of protein. Growth curves were adjusted using nonlinear regression to the measured growth parameters. RESULTS: full enteral diet was reached in 6.3 days by GI and in 10.8 by GII; a weight of 2 kg was reached in 7.3 weeks for GI and in 7.8 for GII. In GI, 3/10 (33.3%) and in GII, 7/30 (23.3%) developed sepsis. Necrotizing enterocolitis did not occur in GI, but in 3/30 (10.0%) in GII. GI presented with urinary calcium > 4 mg/L in 1/10 (10.0%), urinary phosphorus (Pu) <1 mg/L in 10/10 (100%), and Ca/Cr >0.6 ratio in 1/10 (10.0%) of the cases; in GII, no children presented alterations of the urinary calcium or the Ca and Cr ratio, and Pu was <1 mg/L in 19/30 (63.3%). In terms of growth the 50th percentile for GI was a weight gain of 12.1 g/day (GI) vs. 15.8 g/day (GII), a length gain of 0.75 cm/week (GI) vs. 1.02 cm/week (GII), and a head circumference gain of 0.74 cm/week (GI) vs. 0.76 cm/week (GII). CONCLUSIONS: Human milk bank allowed a satisfactory growth and good clinical evolution for very low birth weight infants.

Profiles of Human Milk Oligosaccharides and Production of Some Human Milk Oligosaccharides in Transgenic Animals12

Prieto, Pedro Antonio
Fonte: American Society for Nutrition Publicador: American Society for Nutrition
Tipo: Artigo de Revista Científica
Publicado em 04/05/2012 EN
Relevância na Pesquisa
66.26%
During the decade of the 1990s and the first years of the current century, our group embarked on a project to study and synthesize human milk oligosaccharides. This report describes 2 unexpected collateral observations from that endeavor. The first observation was the detection and confirmation of 2 rare neutral human milk oligosaccharides profiles that were uncovered while assessing oligosaccharide content in hundreds of samples of human milk. One of these lacked fucosylated structures altogether, and the other lacked the oligosaccharide 3-fucosyllactose [Galβ1–4(Fucα1–3)Glc]. We used glycoconjugate probes to determine whether the unusual profiles were mirrored by fucosylation of milk glycoproteins. The results show that the lack of fucosylated oligosaccharides in these samples corresponds to the absence of equivalent fucosylated motifs in milk glycoproteins. The second finding was a shortened and distinct lactation process in transgenic rabbits expressing the human fucosyltransferase 1. During the first day of lactation, these animals expressed milk that contained both lactose and 2′-fucosylactose, but on the second day, the production of milk was severely diminished, and by the fourth day, no lactose was detected in their milk. Meanwhile...

Avaliação dos procedimentos higiênico-sanitários utilizados durante a coleta domiciliar e o transporte do leite humano ordenhado; Assessment of the hygienic-sanitary procedures used during collection and transportation of household human milk

Menezes, Glória
Fonte: Universidade Federal de Uberlândia Publicador: Universidade Federal de Uberlândia
Tipo: Dissertação
POR
Relevância na Pesquisa
66.26%
A promoção da amamentação é considerada umas das principais estratégias para sobrevivência infantil e o Leite Humano (LH) o alimento ideal para o recém-nascido de termo e pré-termo, capaz de garantir nutrientes essenciais para o seu desenvolvimento. Na falta ou volumes insuficientes do leite da própria mãe, especialmente para crianças hospitalizadas como os recém-nascidos pré-termo, a opção pelo leite humano ordenhado (LHO) de doadoras de Bancos de Leite Humano (BLH) torna-se uma alternativa eficaz. Os BLH enquanto entidades de apoio à amamentação captam, processam, e distribuem o LHO de doadoras e neste intuito se faz necessária à otimização operacional e o controle de riscos biológicos para o seu fornecimento seguro. O objetivo deste trabalho foi avaliar os procedimentos higiênico-sanitários praticados pelas doadoras de LH durante a ordenha e o armazenamento domiciliar, bem como o transporte do LHO até o BLH e associar os dados encontrados com os resultados das análises do controle de qualidade. Através da observação da ordenha e armazenamento no domicílio, foram preenchidos um check list com os procedimentos higiênico-sanitários e questionário sócio demográfico. Foram obtidas também as temperaturas das caixas térmicas de transporte do LHO das planilhas rotineiramente preenchidas. Os resultados da avaliação da acidez titulável e do exame microbiológico das amostras coletadas durante a observação foram obtidas nos livros de registro do BLH do Hospital de Clínicas da Universidade Federal de Uberlândia (BLH HC/UFU). Utilizou-se o teste Qui-quadrado...

A randomized trial of supplementation with docosahexaenoic acid-rich tuna oil and its effects on the human milk cytokines interleukin 1beta, interleukin 6, and tumor necrosis factor alpha

Hawkes, J.; Bryan, D.L.; Makrides, M.; Neumann, M.; Gibson, R.
Fonte: Amer Soc Clinical Nutrition Publicador: Amer Soc Clinical Nutrition
Tipo: Artigo de Revista Científica
Publicado em //2002 EN
Relevância na Pesquisa
66.24%
Background: Increased consumption of n-3 long-chain polyunsaturated fatty acids (PUFAs) has been recommended during pregnancy and lactation. The production of proinflammatory cytokines by human peripheral blood mononuclear cells (PBMCs) can be modified by dietary n-3 PUFAs. Objective: We sought to determine whether dietary supplementation of lactating women with docosahexaenoic acid (DHA) can modulate the concentration of cytokines in the aqueous phase of human milk and the production of cytokines by human milk cells (HMCs) and PBMCs. Design: In this double-blind, prospective, randomized trial, mothers of healthy full-term infants were asked to consume daily a nutritional supplement of 2000 mg oil containing either placebo (n = 40), 300 mg DHA + 70 mg eicosapentaenoic acid (EPA; n = 40), or 600 mg DHA + 140 mg EPA (n = 40). The fatty acid composition of plasma, PBMCs, milk, and HMCs from lactating mothers at 4 wk postpartum was measured by gas chromatography. The concentration of interleukin 6 and tumor necrosis factor in milk and the production of interleukin 1ß, tumor necrosis factor , and interleukin 6 by PBMCs and HMCs after stimulation with lipopolysaccharide was measured by enzyme-linked immunosorbent assay. Results: At 4 wk postpartum...

Interleukin-2 in human milk: A potential modulator of lymphocyte development in the breastfed infant

Bryan, D.L.; Forsyth, K.; Gibson, R.; Hawkes, J.
Fonte: Academic Press Ltd Elsevier Science Ltd Publicador: Academic Press Ltd Elsevier Science Ltd
Tipo: Artigo de Revista Científica
Publicado em //2006 EN
Relevância na Pesquisa
66.25%
Development of lymphocyte subpopulations and response to antigen exposure will be influenced by the limited ability of neonates to produce cytokines. In the case of cytokines such as interleukin (IL)-2 which are potent T lymphocyte regulators but poorly produced by newborn infants, the supply of cytokines through human milk could alleviate an immunological deficit and potentially aid the maturation of the immune system. We analysed human milk from 52 mothers (15–357 days postpartum) by ELISA to determine levels of aqueous IL-2, as well as production by human milk cells. IL-2 was detectable (>8 pg/mL) in the aqueous phase of 81% of all day 1 samples with no significant difference found in the mean concentration over 3 consecutive days. IL-2 was produced constitutively at detectable levels by 57% of milk cell samples and production was significantly increased by stimulation with Con A (380%). No correlation was found between aqueous and cellular IL-2, however there was a significant correlation between milk aqueous IL-2 and serum IL-2. This is the first report of IL-2 in the aqueous phase of human milk. A supply of exogenous IL-2 in human milk may provide the suckling infant with important immunological signals during a significant stage of T cell development.; http://www.elsevier.com/wps/find/journaldescription.cws_home/622815/description#description; Dani-Louise Bryan...

Experiencias de donación de leche humana en Andalucía-España: un estudio cualitativo; Experiences of human milk donation in Andalucía-Spain: a qualitative study

da Silva Machado, Raylane; Campos Calderón, Concepción P.; Montoya Juárez, Rafael; Schmidt RioValle, Jacqueline
Fonte: Murcia: Servicio de Publicaciones de la Universidad de Murcia Publicador: Murcia: Servicio de Publicaciones de la Universidad de Murcia
Tipo: Artigo de Revista Científica Formato: application/pdf
SPA
Relevância na Pesquisa
66.27%
Introducción: Los beneficios de la lactancia materna para los bebés han sido bien documentados. Recoger el exceso de leche humana de madres lactantes es un servicio social importante. Los bancos dependen de las donaciones de madres lactantes, por ello la importancia de conocer los aspectos subjetivos que interfieren en la donación. Objetivo: Conocer las vivencias, creencias, motivaciones y dificultades respecto la donación de leche de un grupo de mujeres donantes en el Banco de Leche Humano de Granada-Andalucia. Métodos: Estudio descriptivo, con abordaje cualitativo, realizado en el período de mayo y junio de 2013. La muestra estuvo constituida por 7 mujeres que donaron leche en el banco de leche humana del Hospital Virgen de las Nieves de Granada. Para la recogida de datos se utilizaron entrevistas semiestructuradas. Resultados: Las informantes tenían en su mayoría más de treinta años, con nivel universitario, casadas y con uno o dos hijos como máximo. De los discursos de las madres emergieron las siguientes categorías: Decisión de hacerse donante; Motivaciones donación; Apoyo donación y Dificultades donación. Conclusión: Como se evidencia, el banco de leche es todavía poco conocido. Todavía existen pocos bancos de leche en España...

The Online Sharing of Human Milk: A Content Analysis

Papanicolaou, Alicia
Fonte: Quens University Publicador: Quens University
Tipo: Tese de Doutorado
EN; EN
Relevância na Pesquisa
66.33%
The benefits of human milk are well-known, as human milk provides optimal nutrition in facilitating the growth, health, and development of infants and children. There are circumstances when a mother’s breast milk may be unavailable due to maternal illness, insufficient milk supply, contraindications, or geographical barriers (Dempsey & Miletin, 2010). Global recommendations support the use of donor human milk in situations where a mother’s own breast milk is unavailable (World Health Organization, 2009). Due to the limited supply, the pasteurized product is allocated to high risk infants within the hospitalized setting (Human Milk Bank Association of North America, 2008). Based on the allocation priorities, many individuals are unable to access donor human milk. In response to the growing demands for donor human milk, Internet based organizations have facilitated peer to peer human milk sharing. Given the fact that sharing human milk has been practiced as a covert activity, there is a lack of prevalence data (Thorley, 2008). To date, minimal research has examined this phenomenon. The purpose of this study was to explore the description of sharing human milk utilizing an online commerce-free approach. Data was collected through semi-structured interviews with 13 research participants and analyzed using an inductive approach to qualitative content analysis. Qualitative content analysis was selected based on the recognition of the importance of obtaining a rich description when exploring this phenomenon. Outcomes generated from the research study resulted in emerging concepts and categories. The concepts from the data analysis consisted of the following: commitment to human milk; virtual nature of relationships; and making the private public. The identified categories include: 1) infant feeding practices; 2) experience with sharing human milk; 3) selection of donors or recipients; 4) relationships among donors and recipients sharing human milk; 5) shared doctrine; 6) use of the Internet to share human milk; and 7) informing health care professionals and others regarding sharing human milk. Findings generated from this study provide an increase in understanding of this phenomenon. The cultivated knowledge will assist health care professionals in working in partnership with families to ensure optimal outcomes.; Thesis (Master...

Otimização de metodologia analitica e avaliação da incidencia de cadmio e chumbo em leite humano e alimentos infantis.; Otimization of analytical methodology and evaluation of cadmium and lead incidence in human milk and baby foods.

Adriana Queiroz de Oliveira
Fonte: Biblioteca Digital da Unicamp Publicador: Biblioteca Digital da Unicamp
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 20/07/2005 PT
Relevância na Pesquisa
66.25%
Elementos metálicos, como cádmio e chumbo, uma vez absorvidos pelo organismo, não são completamente eliminados, provocando alterações metabólicas com redução do tempo de vida e da capacidade de trabalho nos indivíduos expostos. Bebês e crianças pequenas constituem a parcela da população que inspira preocupação, do ponto de vista toxicológico, por apresentarem maior absorção que os adultos, em razão de seus organismos não estarem completamente desenvolvidos. Sabe-se que a maior fonte de exposição ao cádmio e ao chumbo, para indivíduos sem exposição ocupacional e não fumantes, é a dieta. Nos primeiros anos de vida, o ser humano possui uma dieta baseada principalmente no leite materno e em alimentos como formulações lácteas, formulações a base de soja, cereais e alimentos na forma de purê. Por esse motivo, levantamentos da contaminação por cádmio ou chumbo nestes alimentos destinados ao público infantil possuem grande importância. O presente trabalho visou obter dados sobre a incidência de cádmio e chumbo em leite humano em seis cidades do Estado de São Paulo (Bauru, Campinas, Presidente Prudente, Ribeirão Preto, São Paulo e Votuporanga), em alimentos infantis como formulações lácteas, formulações a base de soja...

Serum phenylalanine in preterm newborns fed different diets of human milk,

Thomaz,Débora M.; Serafin,Paula O.; Palhares,Durval B.; Tavares,Luciana V.M.; Grance,Thayana R.S.
Fonte: Sociedade Brasileira de Pediatria Publicador: Sociedade Brasileira de Pediatria
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/10/2014 EN
Relevância na Pesquisa
66.3%
Objective:To evaluate phenylalanine plasma profile in preterm newborns fed different human milk diets.Methods:Twenty-four very-low weight preterm newborns were distributed randomly in three groups with different feeding types: Group I: banked human milk plus 5% commercial fortifier with bovine protein, Group II: banked human milk plus evaporated fortifier derived from modified human milk, Group III: banked human milk plus lyophilized fortifier derived from modified human milk. The newborns received the group diet when full diet was attained at 15 ± 2 days. Plasma amino acid analysis was performedon the first and last day of feeding. Comparison among groups was performed by statistical tests: one way ANOVA with Tukey's post-test using SPSS software, version 20.0 (IBM Corp, NY, USA), considering a significance level of 5%.Results:Phenylalanine levels in the first and second analysis were, respectively, in Group I: 11.9 ± 1.22 and 29.72 ± 0.73; in Group II: 11.72 ± 1.04 and 13.44 ± 0.61; and in Group III: 11.3 ± 1.18 and 15.42 ± 0.83 μmol/L.Conclusion:The observed results demonstrated that human milk with fortifiers derived from human milk acted as a good substratum for preterm infant feeding both in the evaporated or the lyophilized form...

Human Milk Supply in Australia

Smith, Julie
Fonte: Elsevier Publicador: Elsevier
Tipo: Artigo de Revista Científica
Relevância na Pesquisa
66.23%
This paper aims to place as monetary value on the actual and potential supply of human milk in Australia. It estimates the quantity of milk produced in 1992. It considers different bases for determining a 'shadow price' for breastmilk, and uses the method established by Oshaug and Botten (Food Policy 19(5), (1994), 479-482). It also calculates scenarios for different prevalences of breastfeeding, looking at the implications on the human milk supply of Australia achieving its National Health Targets, of all mothers breastfeeding according to the optimum regime recommended by the WHO and UNICEF in the Innocenti Declaration of 1990, or of a return to the 'human milk famine' of the early 1970s. It concludes that Australian women supplied 33 million kg of breastmilk in 1992, compared to 16 million kg in 1972. Valued at A$67 per litre (the price of expressed human milk) the 1992 production level was worth $2.2 billion. This is around 0.5% of GDP, or 6% of private spending on food. Achieving international standards for 'optimal' levels of breastfeeding, with breastfeeding continuing up to age two and beyond, would nearly triple the supply of human milk.

Effects of human milk on blood and bone marrow cells in a malnourished mice model: comparative study with cow milk

García,Isabel; Salva,Susana; Zelaya,Hortensia; Villena,Julio; Agüero,Graciela
Fonte: Nutrición Hospitalaria Publicador: Nutrición Hospitalaria
Tipo: info:eu-repo/semantics/article; journal article; info:eu-repo/semantics/publishedVersion Formato: text/html; application/pdf
Publicado em 01/12/2013 ENG
Relevância na Pesquisa
66.26%
Introduction: It has been demonstrated that the alterations caused by nutrient deficiency can be reverted by adequate nutritional repletion. Objective: To perform comparative studies between human and cow milks in order to evaluate the impact of both milks on the recovery of blood and bone marrow cells affected in malnourished mice. Method: Weaned mice were malnourished after consuming a protein free diet for 21 days. Malnourished mice received cow or human milk (CM or HM) for 7 or 14 consecutive days. During the period of administration of milk, the mice consumed the protein free diet ad libitum. The malnourished control (MNC) group received only protein free diet whereas the well-nourished control (WNC) mice consumed the balanced conventional diet. Results and Discussion: Both milks normalized serum albumin levels and improved thymus weight. Human milk was less effective than cow milk to increase body weight and serum transferrin levels. In contrast, human milk was more effective than cow milk to increase the number of leukocytes (WNC: 6.90 ± 1.60ª; MNC: 2.80 ± 0.90b; CM 7d: 3.74 ± 1.10b; HM 7d: 7.16 ± 1.90ª; CM 14d: 4.35 ± 1.20b; HM 14d: 6.75 ± 1.20ª (10(9)/L);p < 0.05) and lymphocytes (WNC: 5.80 ± 0.36ª; MNC: 1.80 ± 0.40b; CM 7d: 2.50 ± 0.30b; HM 7d: 4.20 ± 0.50c; CM 14d: 3.30 ± 0.31d; HM 14d: 4.70 ± 0.28c (10(9)/L);p < 0.05) in peripheral blood. Both milks induced an increment in mitotic pool cells in bone marrow and α-naphthyl butyrate esterase positive cells in peripheral blood. They also normalized phagocytic function in blood neutrophils and oxidative burst in peritoneal cells. Conclusion: Both milks were equally effective to exert favorable effects on the number of the bone marrow cells and the functions of the blood and peritoneal cells involved in immune response. However...