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Xylo-oligosaccharides from lignocellulosic materials: Chemical structure, health benefits and production by chemical and enzymatic hydrolysis

Carvalho, Ana Flávia Azevedo; Neto, Pedro de Oliva; da Silva, Douglas Fernandes; Pastore, Gláucia Maria
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Artigo de Revista Científica Formato: 75-85
ENG
Relevância na Pesquisa
66.01%
Currently, there is worldwide interest in the technological use of agro-industrial residues as a renewable source of food and biofuels. Lignocellulosic materials (LCMs) are a rich source of cellulose and hemicellulose. Hemicellulose is rich in xylan, a polysaccharide used to develop technology for producing alcohol, xylose, xylitol and xylo-oligosaccharides (XOSs). The XOSs are unusual oligosaccharides whose main constituent is xylose linked by β 1-4 bonds. The XOS applications described in this paper highlight that they are considered soluble dietary fibers that have prebiotic activity, favoring the improvement of bowel functions and immune function and having antimicrobial and other health benefits. These effects open a new perspective on potential applications for animal production and human consumption. The raw materials that are rich in hemicellulose include sugar cane bagasse, corncobs, rice husks, olive pits, barley straw, tobacco stalk, cotton stalk, sunflower stalk and wheat straw. The XOS-yielding treatments that have been studied include acid hydrolysis, alkaline hydrolysis, auto-hydrolysis and enzymatic hydrolysis, but the breaking of bonds present in these compounds is relatively difficult and costly, thus limiting the production of XOS. To obviate this limitation...

Assessing the potential health benefits of cycling in the city of Viana do Castelo.

Ribeiro, Paulo; Arsénio, Elisabete; Mendes, José F. G.
Fonte: European Transport Publicador: European Transport
Tipo: Conferência ou Objeto de Conferência
Publicado em //2012 ENG
Relevância na Pesquisa
55.93%
Mobility has an important impact on the overall functioning of cities and quality of life of citizens. On the other hand, motorized road traffic is associated with high levels of noise and air pollutant emissions along with congestion and other externalities, leading to considerable social and environmental costs and degradation of human health. Following the World Health Organization, physical inactivity is one of the leading risks in Europe, associated with nearly 1 million deaths per year . In Portugal around 69% of the adult population do not reach the minimum recommended level of physical activity and 31% were considered sufficiently and highly active. Therefore, more sustainable transport modes such as walking and cycling are envisaged.

Avaliação dos potenciais benefícios para a saúde associados à utilização regular de modos suaves de transporte : um caso de estudo na cidade de Viana do Castelo; Evaluation of potential health benefits associated with regular use of soft modes of transport : a case study in the city of Viana do Castelo

Lourenço, Rui Daniel Pereira
Fonte: Universidade do Minho Publicador: Universidade do Minho
Tipo: Trabalho de Conclusão de Curso
Publicado em //2013 POR
Relevância na Pesquisa
65.99%
Dissertação de mestrado integrado em Engenharia Civil (área de especialização em Perfil de Planeamento e Infraestrututas de Transporte); O automóvel tem sido nas últimas décadas o principal modo de transporte utilizado para realizar as deslocações diárias. Este fato é também, resultante do crescimento económico dos países, regiões e cidades, bem como do investimento centrado nas infraestruturas rodoviárias associado a taxas de motorização elevadas. Este cenário levou a que as cidades fossem projetadas em função do automóvel, pelo que grande parte do espaço público urbano está hoje dedicado à circulação e estacionamento dos veículos automóveis, com os inúmeros inconvenientes para a circulação de outros modos de transporte, designadamente de peões e ciclistas. A conceção de espaços públicos que não privilegiam as deslocações a pé ou de bicicleta, contribuem para aumento do sedentarismo e para um estilo de vida sem atividade física regular, constituindo um fator de risco para o desenvolvimento de diversas doenças crónicas como as doenças cardiovasculares, excesso de peso e obesidade, diabetes, cancro, saúde músculo-esquelética e bem-estar psicológico. Esta dissertação centra-se na temática da relação que existe entre a atividade física regular proporcionada pelos modos de transporte suaves e a saúde...

Improving the Health of Workers in Indoor Environments: Priority Research Needs for a National Occupational Research Agenda

Mendell, Mark J.; Fisk, William J.; Kreiss, Kathleen; Levin, Hal; Alexander, Darryl; Cain, William S.; Girman, John R.; Hines, Cynthia J.; Jensen, Paul A.; Milton, Donald K.; Rexroat, Larry P.; Wallingford, Kenneth M.
Fonte: © American Journal of Public Health 2002 Publicador: © American Journal of Public Health 2002
Tipo: Artigo de Revista Científica
Publicado em /09/2002 EN
Relevância na Pesquisa
55.92%
Indoor nonindustrial work environments were designated a priority research area through the nationwide stakeholder process that created the National Occupational Research Agenda. A multidisciplinary research team used member consensus and quantitative estimates, with extensive external review, to develop a specific research agenda. The team outlined the following priority research topics: building-influenced communicable respiratory infections, building-related asthma/allergic diseases, and nonspecific building-related symptoms; indoor environmental science; and methods for increasing implementation of healthful building practices. Available data suggest that improving building environments may result in health benefits for more than 15 million of the 89 million US indoor workers, with estimated economic benefits of $5 to $75 billion annually. Research on these topics, requiring new collaborations and resources, offers enormous potential health and economic returns.

Effects on Outpatient and Emergency Mental Health Care of Strict Medicaid Early Periodic Screening, Diagnosis, and Treatment Enforcement

Snowden, Lonnie R.; Masland, Mary C.; Wallace, Neal T.; Evans-Cuellar, Allison
Fonte: American Public Health Association Publicador: American Public Health Association
Tipo: Artigo de Revista Científica
Publicado em /11/2007 EN
Relevância na Pesquisa
55.76%
We investigated enforcement of mental health benefits provided by California Medicaid’s Early Periodic Screening, Diagnosis, and Treatment (EPSDT) program. Enforcement, compelled by a consumer-driven lawsuit, resulted in an almost 4-fold funding increase over a 5-year period.

Does earmarked donor funding make it more or less likely that developing countries will allocate their resources towards programmes that yield the greatest health benefits?

Waddington, Catriona
Fonte: World Health Organization Publicador: World Health Organization
Tipo: Artigo de Revista Científica
Publicado em /09/2004 EN
Relevância na Pesquisa
55.87%
It should not be assumed that earmarked donor funding automatically increases the allocation of developing-country resources towards programmes that yield the greatest health benefits. Sometimes it does, sometimes it does not--how the funding is designed can influence this. This is true particularly in the longer term, once the earmarked funding has ended. Even in the short term, total funding does not necessarily increase because of fungibility (i.e. recipient governments adjust their spending to offset donor funding preferences). The author explores six problems with earmarked funding: the multiplicity of earmarked funds confuses the situation for decision-makers; earmarking works against the spirit of the sectorwide approach; from the national perspective, it makes sense not to double-fund activities; local ownership of an activity is often compromised; earmarking can lead governments to accept interventions which they cannot afford in the longer term; and earmarking can distort local resource allocation.

Putting the Whole Grain Puzzle Together: Health Benefits Associated with Whole Grains—Summary of American Society for Nutrition 2010 Satellite Symposium123

Jonnalagadda, Satya S.; Harnack, Lisa; Hai Liu, Rui; McKeown, Nicola; Seal, Chris; Liu, Simin; Fahey, George C.
Fonte: American Society for Nutrition Publicador: American Society for Nutrition
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
66.03%
The symposium “Putting the Whole Grain Puzzle Together: Health Benefits Associated with Whole Grains” sponsored by the ASN brought together researchers to review the evidence regarding the health benefits associated with whole grains. Current scientific evidence indicates that whole grains play an important role in lowering the risk of chronic diseases, such as coronary heart disease, diabetes, and cancer, and also contribute to body weight management and gastrointestinal health. The essential macro- and micronutrients, along with the phytonutrients present in whole grains, synergistically contribute to their beneficial effects. Current evidence lends credence to the recommendations to incorporate whole grain foods into a healthy diet and lifestyle program. The symposium also highlighted the need for further research to examine the role of whole grain foods in disease prevention and management to gain a better understanding of their mechanisms of action.

Beta-carotene: functions, health benefits, adverse effects and applications.

CARVALHO, L. M. J.; ORTIZ, D.-G.; RIBEIRO, E. M. G.; SMIDERLE, L.; PEREIRA, E. J.; CARVALHO, J. L. V.
Fonte: In: LEFEVRE, M. (Ed.). Beta-carotene: functions, health benefits and adverse effects. New York: Nova Biomedical, 2013. cap. 3, p. 59-79. Publicador: In: LEFEVRE, M. (Ed.). Beta-carotene: functions, health benefits and adverse effects. New York: Nova Biomedical, 2013. cap. 3, p. 59-79.
Tipo: Capítulo em livro técnico-científico (ALICE)
EN
Relevância na Pesquisa
55.94%
The purpose of this chapter is to review the main functions, benefits and possible adverse effects of beta-carotene on human health and its applications in food.; 2013

Ethanol as a Husehold Fuel in Madagascar : Health Benefits, Economic Assessment, and Review of African Lessons for Scaling-up; L'ethanol comme combustible domestique a Madagascar avantages relatifs a la sante, evaluation economique et revue des enseignements tires de l'experience africaine en vue d'une mise a l'echelle : rapport sommaire

World Bank
Fonte: Washington, DC Publicador: Washington, DC
Tipo: Economic & Sector Work :: Other Environmental Study; Economic & Sector Work
ENGLISH; EN_US
Relevância na Pesquisa
55.97%
This study was commissioned to analyse the cost efficiency and economic viability of an ethanol programme, for reducing disease, and protecting the forests in Madagascar. This information is also expected to be of interest regionally and internationally, given that the World Health Organization (WHO) estimates that there are nearly two million deaths per annum globally due to Household Air Pollution (HAP), representing 2.7 percent of the global burden of disease. Of these, nearly 400,000 deaths per annum due to HAP, are in sub-Saharan Africa. With only 20 percent of the world's population, Africa suffers a disproportionate share of around half of all deaths from pneumonia for children under five years, for which HAP is a major risk factor. This study investigates the potential of ethanol as a household fuel in Madagascar, focusing on three main components: health benefits, financial and economic assessment, and African lessons for scaling-up a program of support for ethanol as a household fuel.

The Health Benefits of Transport Projects : A Review of the World Bank Transport Sector Lending Portfolio

Freeman, Peter; Mathur, Kavita
Fonte: Washington, DC : World Bank Publicador: Washington, DC : World Bank
Tipo: Publications & Research :: Publication; Publications & Research :: Publication
ENGLISH; EN_US
Relevância na Pesquisa
56.13%
This paper reviews the contribution of the World Bank's transport lending portfolio to health outcomes, as background for the Independent Evaluation Group's (IEG) evaluation of the Bank's support for health, nutrition and population (HNP). Over the past decade (FY97-06), the World Bank committed nearly $28 billion to 229 new transport projects managed by the Transport Sector Board (TSB). Specifically, the paper reviews the extent to which these projects: cite potential health benefits or risks in design documents; include specific objectives with respect to improving health outcomes or mitigating health risks; propose environmental improvements that are likely to provide health benefits; target transport services, and both health and behavioral outcomes to the poor; and plans to collect evidence on changes in health outcomes as a result of transport interventions. For completed projects, it assesses the extent to which expected health benefits or objectives have been achieved. This review of health benefits in the transport lending portfolio over the past decade shows that in the majority of the cases the focus has been on improvements in road safety...

Investigating active transportation to and from school : identification of predictors and health benefits

Pabayo, Roman A.
Fonte: Université de Montréal Publicador: Université de Montréal
Tipo: Thèse ou Mémoire numérique / Electronic Thesis or Dissertation
EN
Relevância na Pesquisa
55.95%
Contexte : Les données probantes rapportées au cours des 20 dernières années indiquent un déclin important de la pratique d’activités physiques. Les chercheurs considèrent que la diminution de l’activité physique est un facteur clé de l’augmentation du surpoids et de l’obésité chez les enfants. Les transport actifs (TA), à savoir les modes de transport non motorisés tels la marche ou le vélo pour aller à l’école ou en revenir, pourraient constituer une opportunité de pratique d’activité physique. Objective : Cette thèse vise à identifier les déterminants individuels et écologiques du TA et d’en évaluer les retombées de santé possibles. Quatre études visant les objectifs suivants ont été réalisés: (1) Parmi un échantillon d’enfants et d’adolescents québécois, décrire la proportion d’enfants qui utilisent la marche, le transport en commun, le véhicule familial, l’autobus scolaire ou une combinaison de modes de déplacement pour se déplacer vers l’école. (2) Identifier les facteurs associés au TA pour se déplacer vers l’école parmi un échantillon d’enfants et d’adolescents québécois. (3) Parmi des échantillons de jeunes québécois et canadiens, identifier les déterminants individuels et écologiques du TA pour se déplacer vers l’école. (4) Examiner l’association entre le TA pour se déplacer vers l’école et les changements d’indice de masse corporelle (IMC) entre la maternelle et la 2e année du primaire. Méthodologie : Trois bases de données avec échantillonnage de type populationnel ont été utilisées pour répondre à ces objectifs de recherche...

Assessing the health benefits of air pollution reduction for children.

Wong, Eva Y; Gohlke, Julia; Griffith, William C; Farrow, Scott; Faustman, Elaine M
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /02/2004 EN
Relevância na Pesquisa
46.16%
Benefit-cost analyses of environmental regulations are increasingly mandated in the United States. Evaluations of criteria air pollutants have focused on benefits and costs associated with adverse health effects. Children are significantly affected by the health benefits of improved air quality, yet key environmental health policy analyses have not previously focused specifically on children's effects. In this article we present a "meta-analysis" approach to child-specific health impacts derived from the U.S. Clean Air Act (CAA). On the basis of data from existing studies, reductions in criteria air pollutants predicted to occur by 2010 because of CAA regulations are estimated to produce the following impacts: 200 fewer expected cases of postneonatal mortality; 10,000 fewer asthma hospitalizations in children 1-16 years old, with estimated benefits ranging from 20 million U.S. dollars to 46 million U.S. dollars (1990 U.S. dollars); 40,000 fewer emergency department visits in children 1-16 years old, with estimated benefits ranging from 1.3 million U.S. dollars to 5.8 million U.S. dollars; 20 million school absences avoided by children 6-11 years old, with estimated benefits of 0.7-1.8 billion U.S. dollars; and 10,000 fewer infants of low birth weight...

Flavonoids in Food and Their Health Benefits

Yao, Liu H.; Jiang, Y. M.; Shi, J.; Tomás Barberán, Francisco; Datta, Nivedita; Singanusong, Riantong; Chen, S. S.
Fonte: Springer Publicador: Springer
Tipo: Artículo Formato: 259768 bytes; application/pdf
ENG
Relevância na Pesquisa
55.94%
10 pages, 2 tables, 2 figures.-- Printed version published July 2004.; There has been increasing interest in the research of flavonoids from dietary sources, due to growing evidence of the versatile health benefits of flavonoids through epidemiological studies. As occurrence of flavonoids is directly associated with human daily dietary intake of antioxidants, it is important to evaluate flavonoid sources in food. Fruits and vegetables are the main dietary sources of flavonoids for humans, along with tea and wine. However, there is still difficulty in accurately measuring the daily intake of flavonoids because of the complexity of existence of flavonoids from various food sources, the diversity of dietary culture, and the occurrence of a large amount of flavonoids itself in nature. Nevertheless, research on the health aspects of flavonoids for humans is expanding rapidly. Many flavonoids are shown to have antioxidative activity, free-radical scavenging capacity, coronary heart disease prevention, and anticancer activity, while some flavonoids exhibit potential for anti–human immunodeficiency virus functions. As such research progresses, further achievements will undoubtedly lead to a new era of flavonoids in either foods or pharmaceutical supplements. Accordingly...

Contrasts in active transport behaviour across four countries: How do they translate into public health benefits?

G?tschi, Thomas; Tainio, Marko; Maizlish, Neil; Schwanen, Tim; Goodman, Anna; Woodcock, James
Fonte: Elsevier Publicador: Elsevier
Tipo: Article; published version
EN
Relevância na Pesquisa
56.04%
This is the final version of the article. It first appeared from Elsevier via http://dx.doi.org/10.1016/j.ypmed.2015.02.009; Objective: Countries and regions vary substantially in transport related physical activity that people gain from walking and cycling and in how this varies by age and gender. This study aims to quantify the population health impacts of differences between four settings. Method: The Integrated Transport and Health Model (ITHIM) was used to estimate health impacts from changes to physical activity that would arise if adults in urban areas in England and Wales adopted travel patterns of Switzerland, the Netherlands, and California.The model was parameterised with data from travel surveys from each setting and estimated using Monte Carlo simulation. Two types of scenarios were created, one in which the total travel time budget was assumed to be fixed and one where total travel times varied. Results: Substantial population health benefits would accrue if people in England and Wales gained as much transport related physical activity as people in Switzerland or the Netherlands, whilst smaller but still considerable harms would occur if active travel fell to the level seen in California. The benefits from achieving the travel patterns of the high cycling Netherlands or high walking Switzerland were similar. Conclusion: Differences between high income countries in how people travel have important implications for population health.; The work was undertaken under the auspices of the Centre for Diet and Activity Research (CEDAR)...

Pet Ownership and Health in Older Adults: Findings from a Survey of 2551 Community Based Australians Aged 60- 64

Parslow, Ruth; Jorm, Anthony F; Christensen, Helen; Rodgers, Bryan; Jacomb, Trish
Fonte: S Karger AG Publicador: S Karger AG
Tipo: Artigo de Revista Científica
Relevância na Pesquisa
56.1%
Background: It is commonly assumed that owning a pet provides older residents in the community with health benefits including improved physical health and psychological well-being. It has also been reported that pet owners are lower on neuroticism and higher on extraversion compared with those without pets. However, findings of research on this topic have been mixed with a number of researchers reporting that, for older people, there is little or no health benefit associated with pet ownership. Objective: To identify health benefits associated with pet ownership and pet caring responsibilities in a large sample of older community-based residents. Methods: Using survey information provided by 2,551 individuals aged between 60 and 64 years, we compared the sociodemographic attributes, mental and physical health measures, and personality traits of pet owners and nonowners. For 78.8% of these participants, we were also able to compare the health services used, based on information obtained from the national insurer on the number of general practitioner (GP) visits they made over a 12-month period. Results: Compared with non-owners, those with pets reported more depressive symptoms while female pet owners who were married also had poorer physical health. We found that caring for a pet was associated with negative health outcomes including more symptoms of depression...

Estimating the health and economic benefits associated with reducing air pollution in the Barcelona metropolitan area (Spain)

Pérez,Laura; Sunyer,Jordi; Künzli,Nino
Fonte: Gaceta Sanitaria Publicador: Gaceta Sanitaria
Tipo: info:eu-repo/semantics/article; journal article; info:eu-repo/semantics/publishedVersion Formato: text/html; application/pdf
Publicado em 01/08/2009 ENG
Relevância na Pesquisa
46.15%
Objectives: To estimate the health and economic benefits that would result from two scenarios of improved air quality in 57 municipalities of the metropolitan area of Barcelona. Methods: We used attributable fractions and life tables to quantify the benefits for selected health outcomes, based on published concentration-response functions and economic unit values. The mean weighted concentration of PM10 for the study population was estimated through concentration surface maps developed by the local government. Results: The annual mean health benefits of reducing the mean PM10 exposure estimated for the population in the study area (50µg/m³) to the annual mean value recommended by the World Health Organization (20µg/m³) were estimated to be 3,500 fewer deaths (representing an average increase in life expectancy of 14 months), 1,800 fewer hospitalizations for cardio-respiratory diseases, 5,100 fewer cases of chronic bronchitis among adults, 31,100 fewer cases of acute bronchitis among children, and 54,000 fewer asthma attacks among children and adults. The mean total monetary benefits were estimated to be 6,400 million euros per year. Reducing PM10 to comply with the current European Union regulatory annual mean level (40µg/m³) would yield approximately one third of these benefits. Conclusions: This study shows that reducing air pollution in the metropolitan area of Barcelona would result in substantial health and economic benefits. The benefits are probably underestimated due to the assumptions made in this study. Assessment of the health impact of local air pollution is a useful tool in public health.

WHO Framework Convention on Tobacco Control: a global ‘‘good’’ for public health

Taylor,Allyn L.; Bettcher,Douglas W.
Fonte: World Health Organization Publicador: World Health Organization
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/07/2000 EN
Relevância na Pesquisa
55.83%
Although the application of legal instruments to international health issues - relative to other areas of international concern - is still at a rudimentary stage of development, the transnational health impacts of globalization provide a rationale for the codification and implementation of global norms to deal with shared problems. The experience of promulgating international agreements in other areas closely related to international health - the environment, for example - demonstrates how evidence-based international agreements can effectively address a range of problems that cross national boundaries. The framework convention-protocol approach is a legally binding, incremental approach to international law-making that has frequently been employed to deal with environmental threats, and is now being adapted to serve purely public health ends. Experience with the recently initiated WHO Framework Convention on Tobacco Control provides a case study of how transnational public health problems can be addressed by an international legal approach. Scientific evidence in public health and economics has provided the foundation for the elaboration of this evidence-based strategy. The present tobacco epidemic poses a range of transnational challenges that are best addressed through coordinated action. In this article...

Health benefits of reduced patient cost sharing in Japan

Nishi,Akihiro; McWilliams,J Michael; Noguchi,Haruko; Hashimoto,Hideki; Tamiya,Nanako; Kawachi,Ichiro
Fonte: World Health Organization Publicador: World Health Organization
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/2012 EN
Relevância na Pesquisa
55.97%
OBJECTIVE: To assess the effect on out-of-pocket medical spending and physical and mental health of Japan's reduction in health-care cost sharing from 30% to 10% when people turn 70 years of age. METHODS: Study data came from a 2007 nationally-representative cross-sectional survey of 10 293 adults aged 64 to 75 years. Physical health was assessed using a 16-point scale based on self-reported data on general health, mobility, self-care, activities of daily living and pain. Mental health was assessed using a 24-point scale based on the Kessler-6 instrument for nonspecific psychological distress. The effect of reduced cost sharing was estimated using a regression discontinuity design. FINDINGS: For adults aged 70 to 75 years whose income made them ineligible for reduced cost sharing, neither out-of-pocket spending nor health outcomes differed from the values expected on the basis of the trend observed in 64- to 69-year-olds. However, for eligible adults aged 70 to 75 years, out-of-pocket spending was significantly lower (P < 0.001) and mental health was significantly better (P < 0.001) than expected. These differences emerged abruptly at the age of 70 years. Moreover, the mental health benefits were similar in individuals who were and were not using health-care services (P = 0.502 for interaction). The improvement in physical health after the age of 70 years in adults eligible for reduced cost-sharing tended to be greater than in non-eligible adults (P = 0.084). CONCLUSION: Reduced cost sharing was associated with lower out-of-pocket medical spending and improved mental health in older Japanese adults.

Does earmarked donor funding make it more or less likely that developing countries will allocate their resources towards programmes that yield the greatest health benefits?

Waddington,Catriona
Fonte: World Health Organization Publicador: World Health Organization
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/09/2004 EN
Relevância na Pesquisa
65.93%
It should not be assumed that earmarked donor funding automatically increases the allocation of developing-country resources towards programmes that yield the greatest health benefits. Sometimes it does, sometimes it does not - how the funding is designed can influence this. This is true particularly in the longer term, once the earmarked funding has ended. Even in the short term, total funding does not necessarily increase because of fungibility (i.e. recipient governments adjust their spending to offset donor funding preferences). The author explores six problems with earmarked funding: the multiplicity of earmarked funds confuses the situation for decision-makers; earmarking works against the spirit of the sectorwide approach; from the national perspective, it makes sense not to double-fund activities; local ownership of an activity is often compromised; earmarking can lead governments to accept interventions which they cannot afford in the longer term; and earmarking can distort local resource allocation.

Estimating the health and economic benefits associated with reducing air pollution in the Barcelona metropolitan area (Spain)

Pérez,Laura; Sunyer,Jordi; Künzli,Nino
Fonte: Ediciones Doyma, S.L. Publicador: Ediciones Doyma, S.L.
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/08/2009 EN
Relevância na Pesquisa
46.15%
Objectives: To estimate the health and economic benefits that would result from two scenarios of improved air quality in 57 municipalities of the metropolitan area of Barcelona. Methods: We used attributable fractions and life tables to quantify the benefits for selected health outcomes, based on published concentration-response functions and economic unit values. The mean weighted concentration of PM10 for the study population was estimated through concentration surface maps developed by the local government. Results: The annual mean health benefits of reducing the mean PM10 exposure estimated for the population in the study area (50µg/m³) to the annual mean value recommended by the World Health Organization (20µg/m³) were estimated to be 3,500 fewer deaths (representing an average increase in life expectancy of 14 months), 1,800 fewer hospitalizations for cardio-respiratory diseases, 5,100 fewer cases of chronic bronchitis among adults, 31,100 fewer cases of acute bronchitis among children, and 54,000 fewer asthma attacks among children and adults. The mean total monetary benefits were estimated to be 6,400 million euros per year. Reducing PM10 to comply with the current European Union regulatory annual mean level (40µg/m³) would yield approximately one third of these benefits. Conclusions: This study shows that reducing air pollution in the metropolitan area of Barcelona would result in substantial health and economic benefits. The benefits are probably underestimated due to the assumptions made in this study. Assessment of the health impact of local air pollution is a useful tool in public health.