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Dietary glycemic load, glycemic index, and refined grains intake are associated with reduced β-cell function in prediabetic Japanese migrants; Associação entre carga glicêmica da dieta, índice glicêmico e consumo de cereais refinados e função reduzida das células-β em migrantes japoneses com pré-diabetes

SARTORELLI, Daniela Saes; FRANCO, Laércio Joel; DAMIÃO, Renata; GIMENO, Suely; CARDOSO, Marly Augusto; FERREIRA, Sandra Roberta Gouvea
Fonte: Sociedade Brasileira de Endocrinologia e Metabologia Publicador: Sociedade Brasileira de Endocrinologia e Metabologia
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
66.57%
OBJECTIVE: To investigate the association between carbohydrate intakes and β-cell function (HOMA-β) in Japanese-Brazilians with impaired glucose tolerance (IGT). METHODS: Dietary intakes were assessed by a validated food frequency questionnaire in a cross-sectional survey carried out in 2000. The associations between diet and HOMA-β were verified in 270 newly diagnosed IGT in multiple linear regression models. RESULTS: The mean (SD) age was 58 (11) years and the mean HOMA-β was 65 (47). The glycemic load was inversely associated with HOMA-β, β1 -0.140 (95%CI = -1.044; -0.078), p = 0.023. The inverse association was also observed for refined grains intakes: -0.186 (95%CI = -0.4862; -0.058), p = 0.012. After adjustments for body mass index, the glycemic index was inversely associated with HOMA-β: -0.1246 (95%CI = -2.2482, -0.0257), p < 0.001. CONCLUSIONS: These data suggested that dietary glycemic load, glycemic index, and refined grains intakes are associated with reduced β-cell function, and the quality of dietary carbohydrates may be relevant for maintaining β-cell function among individuals with IGT.; OBJETIVO: Investigar a associação entre o consumo de carboidratos e função das células-β (HOMA-β) em nipo-brasileiros portadores de tolerância à glicose diminuída (TGD). MÉTODOS: O consumo alimentar habitual foi avaliado por meio do questionário quantitativo de frequência alimentar previamente validado em estudo transversal conduzido em 2000. A associação entre dieta e HOMA-β foi verificada em 270 indivíduos portadores de TGD em modelos de regressão logística ajustados. RESULTADOS: A média (DP) de idade foi 58 (11) anos e do HOMA-β foi 65 (47). A carga glicêmica foi inversamente associada ao HOMA-β...

Effects of processing methods on amaranth starch digestibility and predicted glycemic index

CAPRILES, V. D.; COELHO, K. D.; GUERRA-MATIAS, A. C.; AREAS, J. A. G.
Fonte: BLACKWELL PUBLISHING Publicador: BLACKWELL PUBLISHING
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
66.45%
Amaranth has attracted a great deal of interest in recent decades due to its valuable nutritional, functional, and agricultural characteristics. Amaranth seeds can be cooked, popped, roasted, flaked, or extruded for consumption. This study compared the in vitro starch digestibility of processed amaranth seeds to that of white bread. Raw seeds yielded rapidly digestible starch content (RDS) of 30.7% db and predicted glycemic index (pGI) of 87.2, the lowest among the studied products. Cooked, extruded, and popped amaranth seeds had starch digestibility similar to that of white bread (92.4, 91.2, and 101.3, respectively), while flaked and roasted seeds generated a slightly increased glycemic response (106.0 and 105.8, respectively). Cooking and extrusion did not alter the RDS contents of the seeds. No significant differences were observed among popped, flaked, and roasted RDS contents (38.0%,46.3%, and 42.9%, respectively), which were all lower than RDS content of bread (51.1%). Amaranth seed is a high glycemic food most likely because of its small starch granule size, low resistant starch content (< 1%), and tendency to completely lose its crystalline and granular starch structure during those heat treatments.; FAPESP State of Sao Paulo Research Foundation

Índice glicêmico da dieta habitual e alteração da homeostase glicêmica em nipo-brasileiros de Bauru; Dietary glycemic index in relation to impaired glucose homeostasis disturbances in Japanese-Brazilians living in Bauru.

Sartorelli, Daniela Saes
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 26/04/2005 PT
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Objetivos. Investigar a associação entre consumo alimentar, índice glicêmico (IG) da dieta habitual com glicemia e insulinemia de jejum, resistência à insulina (HOMA R) e alteração da homeostase glicêmica (AHG: glicemia de jejum alterada - GJA, tolerância à glicose diminuída - TGD e diabetes mellitus tipo 2). Indivíduos e métodos. 1.054 nipo-brasileiros residentes em Bauru, ambos os sexos, 30 a 90 anos, primeira e segunda gerações, que participaram de inquérito transversal conduzido em 2000, sem diagnóstico prévio de AHG e/ou uso de hipoglicemiantes orais/insulina. Para avaliação da dieta habitual, utilizou-se questionário quantitativo de freqüência alimentar, previamente validado, com o auxílio do programa Dietsys versão 4.0. Os fatores dietéticos foram ajustados pelas calorias totais pelo método residual, após transformação logarítmica. As variáveis independentes foram inicialmente selecionadas segundo correlação de Pearson com glicemia e insulinemia de jejum ou HOMA R (variáveis dependentes contínuas) com valor de p<0,20. A associação entre nutrientes/ alimentos com as variáveis dependentes contínuas foi avaliada em modelos de regressão linear múltiplos. Modelos de regressão logística múltiplos foram utilizados para investigar a relação entre fatores dietéticos (tercis) com AHG...

Índice glicêmico e carga glicêmica de frutos brasileiros; Glycemic index and glycemic load of Brazilian fruits

Souza, Alessandra Gonçalves de
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 02/03/2005 PT
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Os carboidratos presentes nos alimentos são responsáveis por mais da metade do valor energético da alimentação do homem. Além do aporte energético, esse nutriente tem importante função na manutenção da glicose sanguínea e na integridade e funcionamento do trato gastrintestinal. Os produtos finais da digestão de carboidratos consistem, quase que exclusivamente, em glicose, frutose e galactose. Os carboidratos digeridos e absorvidos no intestino delgado provocam alterações na resposta glicêmica; essa elevação, ao longo do tempo, depende de fatores que interferem na velocidade de digestão e de difusão dos produtos de hidrólise no intestino delgado. Os carboidratos podem ser classificados de acordo com a glicemia pós prandial produzida. O índice glicêmico (IG) expressa de forma indireta, como cada alimento se comporta em termos de velocidade de digestão e absorção de seus carboidratos. A partir dos valores de IG dos alimentos pode-se calcular a carga glicêmica (CG), a qual inclui tanto a quantidade como a qualidade dos carboidratos ingeridos. O presente estudo teve como objetivo avaliar o IG e a CG de cinco frutos nacionais em indivíduos saudáveis. Em cada ensaio foram elaboradas as curvas glicêmicas produzidas após a ingestão de porções contento exatamente 25g ou 50g de carboidrato disponível dos seguintes frutos: abacaxi pérola (Ananas comosus); amora silvestre (Rubus rosaefoluis); morango oso grande (Fragaria ananassa Duch) e bananas (Musa spp.) mysore e nanica. A partir da relação entre a área abaixo da curva glicêmica dos alimentos teste e a área do pão (controle) foi calculado o IG. A CG foi calculada para cada fruto de acordo com o seu IG e a quantidade de alimento consumida habitualmente pela população. Tanto o cerne quanto a polpa de abacaxi apresentaram alto IG. A banana nanica apresentou IG médio e os demais frutos...

Papel do índice glicêmico e da carga glicêmica na prevenção e no controle metabólico de pacientes com diabetes melito tipo 2; Glycemic index and glycemic load in the prevention and treatment of type 2 diabetes mellitus

Silva, Flávia Moraes; Steemburgo, Thais; Azevedo, Mirela Jobim de; Mello, Vanessa Derenji Ferreira de
Fonte: Universidade Federal do Rio Grande do Sul Publicador: Universidade Federal do Rio Grande do Sul
Tipo: Artigo de Revista Científica Formato: application/pdf
POR
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O controle glicêmico intensificado pode prevenir e/ou retardar o aparecimento das complicações crônicas do diabetes melito (DM). O carboidrato da dieta é o principal determinante da glicemia pós-prandial, sendo o índice glicêmico (IG) e a carga glicêmica úteis para prever a resposta glicêmica aos alimentos. O objetivo deste manuscrito foi revisar criticamente o papel das dietas de baixo IG na prevenção e controle metabólico do diabetes melito tipo 2 (DMT2). O risco para desenvolvimento de DMT2 com dietas de alto IG variou de 1,21 a 1,59. A redução de 12 a 32 unidades no IG da dieta diminuiu em 0,39 a 0,50 pontos percentuais a HbA1c. Os efeitos dessas dietas no perfil lipídico e peso corporal no DMT2 permanecem controversos. Em conclusão, as evidências atuais indicam que a incorporação do IG no planejamento dietético de pacientes com DMT2 contribui para a melhora do controle glicêmico.; The tight glycemic control can prevent and/or delay the development of chronic complications of diabetes mellitus (DM). Dietary carbohydrates are the main determinant of postprandial blood glucose and glycemic index (GI) and glycemic load are used to predict blood glucose response to foods. The aim of this paper was to critically review the role of low GI diets in type 2 diabetes mellitus (T2DM) prevention and metabolic control. The risk for development of T2DM with high GI diets ranged from 1.21 to 1.59.The reduction from 12-32 units in the GI of diets decreased 0.39-0.50% in HbA1c values. However...

Diet compounds, glycemic index and obesity-related cardiac effects

Diniz, Yeda S.; Burneiko, Regina M.; Seiva, Fabio R. F.; Almeida, Flávia Queiroga Aranha de; Galhardi, Cristiano Machado; Novelli Filho, Jose Luiz V. B.; Mani, Fernanda; Novelli, Ethel L. B.
Fonte: Elsevier B.V. Publicador: Elsevier B.V.
Tipo: Artigo de Revista Científica Formato: 92-99
ENG
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Background: Diet compounds may influence obesity-related cardiac oxidative stress and metabolic sifting. Carbohydrate-rich diet may be disadvantageous from fat-rich diet to cardiac tissue and glycemic index rather than lipid profile may predict the obesity-related cardiac effects.Materials and methods: Male Wistar rats were divided into three groups (n=8/group): (C) receiving standard chow (3.0 kcal/g); (CRD) receiving carbohydrate-rich diet (4.0 kcal/g), and (FRD) receiving fat-rich diet (4.0 kcal/g). Rats were sacrificed after the oral glucose tolerance test (OGTT) at 60 days of dietary treatments. Lipid profile and oxidative stress parameters were determined in serum. Myocardial samples were used to determine oxidative stress, metabolic enzymes, glycogen and triacylglycerol.Results: FRD rats showed higher final body weight and body mass index than CRD and C. Serum cholesterol and low-density lipoprotein were higher in FRD than in CRD, while triacylglycerol and oxidized low-density lipoprotein cholesterol were higher in CRD than in FRD. CRD rats had the highest myocardial lipid hydroperoxide and diminished superoxide dismutase and catalase activities. Myocardial glycogen was lower and triacylglycerol was higher in CRD than in C and FRD rats. Although FRD rats had depressed myocardial-reducing power...

Dietary glycemic load, glycemic index, and refined grains intake are associated with reduced β-cell function in prediabetic Japanese migrants

Sartorelli,Daniela Saes; Franco,Laércio Joel; Damião,Renata; Gimeno,Suely; Cardoso,Marly Augusto; Ferreira,Sandra Roberta Gouvea
Fonte: Sociedade Brasileira de Endocrinologia e Metabologia Publicador: Sociedade Brasileira de Endocrinologia e Metabologia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/2009 EN
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66.57%
OBJECTIVE: To investigate the association between carbohydrate intakes and β-cell function (HOMA-β) in Japanese-Brazilians with impaired glucose tolerance (IGT). METHODS: Dietary intakes were assessed by a validated food frequency questionnaire in a cross-sectional survey carried out in 2000. The associations between diet and HOMA-β were verified in 270 newly diagnosed IGT in multiple linear regression models. RESULTS: The mean (SD) age was 58 (11) years and the mean HOMA-β was 65 (47). The glycemic load was inversely associated with HOMA-β, β1 -0.140 (95%CI = -1.044; -0.078), p = 0.023. The inverse association was also observed for refined grains intakes: -0.186 (95%CI = -0.4862; -0.058), p = 0.012. After adjustments for body mass index, the glycemic index was inversely associated with HOMA-β: -0.1246 (95%CI = -2.2482, -0.0257), p < 0.001. CONCLUSIONS: These data suggested that dietary glycemic load, glycemic index, and refined grains intakes are associated with reduced β-cell function, and the quality of dietary carbohydrates may be relevant for maintaining β-cell function among individuals with IGT.

Evaluation of the in vitro glycemic index of a fiber-rich extruded breakfast cereal produced with organic passion fruit fiber and corn flour

Leoro,Maria Gabriela Vernaza; Clerici,Maria Teresa Pedrosa Silva; Chang,Yoon Kil; Steel,Caroline Joy
Fonte: Sociedade Brasileira de Ciência e Tecnologia de Alimentos Publicador: Sociedade Brasileira de Ciência e Tecnologia de Alimentos
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2010 EN
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66.34%
The aim of this study was to determine the influence of process parameters and Passion Fruit Fiber (PFF) addition on the Glycemic Index (GI) of an extruded breakfast cereal. A 2³ Central Composite Rotational Design (CCRD) was used, with the following independent variables: raw material moisture content (18-28%), 2nd and 3rd barrel zone temperatures (120-160 ºC), and PFF (0-30%). Raw materials (organic corn flour and organic PFF) were characterized as to their proximate composition, particle size, and in vitro GI. The extrudates were characterized as to their in vitro GI. The Response Surface Methodology (RSM) and Principal Component Analysis (PCA) were used to analyze the results. Corn flour and PFF presented 8.55 and 7.63% protein, 2.61 and 0.60% fat, 0.52 and 6.17% ash, 78.77 and 78.86% carbohydrates (3 and 64% total dietary fiber), respectively. The corn flour particle size distribution was homogeneous, while PFF presented a heterogeneous particle size distribution. Corn flour and PFF presented values of GI of 48 and 45, respectively. When using RSM, no effect of the variables was observed in the GI of the extrudates (average value of 48.41), but PCA showed that the GI tended to be lower when processing at lower temperatures (<128 ºC) and at higher temperatures (>158 ºC). When compared to white bread...

Effect of glycemic index on satiety and body weight

Alfenas,Rita de Cássia Gonçalves; Paiva,Enauê
Fonte: Pontifícia Universidade Católica de Campinas Publicador: Pontifícia Universidade Católica de Campinas
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/04/2007 EN
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Despite extensive study, the practical significance of the glycemic index of food is still debatable. The purpose of this review paper was to evaluate the effect of glycemic index on food intake and body weight based on the analysis of published studies about this topic. According to some authors, ingestion of high glycemic index diets tends to enhance appetite and promote positive energy balance. The increase of appetite associated with the ingestion of these diets is attributed to an especially sharp early post-prandial rise of blood glucose followed by a marked release of insulin and subsequent rebound relative hypoglycemia and low levels of blood fatty acids, suggesting the difficulty that the body has to access its stored metabolic fuels. Short-term investigations have generally demonstrated that ingestion of low glycemic index foods results in greater satiety and lower energy intake than high glycemic index foods. However, less is known about the importance of glycemic index to energy balance and weight control associated with chronic ingestion of foods differing in glycemic index. Carefully designed long-term studies are required to assess the efficacy of glycemic index in the treatment and prevention of obesity in humans.

Use of the glycemic index in nutrition education

Cândido,Flávia Galvão; Pereira,Elisângela Vitoriano; Alfenas,Rita de Cássia Gonçalves
Fonte: Pontifícia Universidade Católica de Campinas Publicador: Pontifícia Universidade Católica de Campinas
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/02/2013 EN
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Recently, the lack of studies providing practical guidance for the use of the glycemic index has been indicated as the cause of its little use in nutrition education. The aim of this study is to give instructions on the use of the glycemic index as a tool to be used in nutrition education to estimulate the consumption of low glycemic index foods. Studies published over the past 12 years, in addition to classic studies on this topic, found in the databases MedLine, ScienceDirect, SciELO and Lilacs exploring the importance of the glycemic index and the factors that affect the glycemic index were selected for this article. The preparation of lists grouping foods according to their glycemic index should be based on information found in tables and specific web sites. This is an interesting strategy that must be very carefully conducted, considering the eating habits of the assisted people. To reduce the postprandial blood glucose response, high glycemic index foods should be consumed in association with the following foods: high protein and low fat foods, good quality oils and unprocessed foods with high fiber content. Caffeine should also be avoided. The glycemic index should be considered as an additional carbohydrate-selection tool, which should be part of a nutritionally balanced diet capable of promoting and/or maintaining body weight and health.

Glycemic index: effect of food storage under low temperature

Carreira,Marina Cassab; Lajolo,Franco Maria; Menezes,Elizabete Wenzel de
Fonte: Instituto de Tecnologia do Paraná - Tecpar Publicador: Instituto de Tecnologia do Paraná - Tecpar
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/08/2004 EN
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This study was carried out to evaluate the influence of food storage under low temperature (-20ºC) and the resistant starch formation, both on the glycemic index (GI). The GI of only cooked and cooked and stored foods under -20ºC for 30 days was evaluated in short-term tests with humans. Significant increase on the RS content was evidenced for all the stored foods. The food storage resulted in a significant decrease on the GI of beans and chick-peas; the GI of pasta remained the same and the GI of corn meal increased. Thus, the RS formation showed reduced influence on the glycemic index. The storage of starchy foods under low temperature can collaborate to the RS intake but its effect on the GI will depend on the characteristics of the carbohydrates of each food.

Effect of glycemic index on obesity control

Pereira,Elisângela Vitoriano; Costa,Jorge de Assis; Alfenas,Rita de Cássia Gonçalves
Fonte: Sociedade Brasileira de Endocrinologia e Metabologia Publicador: Sociedade Brasileira de Endocrinologia e Metabologia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/2015 EN
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Objective Evaluate the effect of glycemic index (GI) on biochemical parameters, food intake, energy metabolism, anthropometric measures and body composition in overweight subjects.Materials and methods Simple blind study, in which nineteen subjects were randomly assigned to consume in the laboratory two daily low GI (n = 10) or high GI (n = 9) meals, for forty-five consecutive days. Habitual food intake was assessed at baseline. Food intake, anthropometric measures and body composition were assessed at each 15 days. Energy metabolism and biochemical parameters were evaluated at baseline and the end of the study.Results Low GI meals increased fat oxidation, and reduced waist circumference and HOMA-IR, while high GI meals increased daily dietary fiber and energy intake compared to baseline. There was a higher reduction on waist circumference and body fat, and a higher increase on postprandial fat oxidation in response to the LGI meals than after high GI meals. High GI meals increased fasting respiratory coefficient compared to baseline and low GI meals.Conclusion The results of the present study showed that the consumption of two daily low GI meals for forty-five consecutive days has a positive effect on obesity control, whereas, the consumption of high GI meals result has the opposite effect. Arch Endocrinol Metab. 2015;59(3):245-51

An extruded breakfast cereal made from a high amylose barley cultivar has a low glycemic index and lower plasma insulin response than one made from a standard barley

King, R.; Noakes, M.; Bird, A.; Morell, M.; Topping, D.
Fonte: Academic Press Ltd Elsevier Science Ltd Publicador: Academic Press Ltd Elsevier Science Ltd
Tipo: Artigo de Revista Científica
Publicado em //2008 EN
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Himalaya 292 is a novel hull-less barley cultivar with lower total starch content, a higher proportion of amylose and a substantially higher content of soluble and insoluble fibre. The high fibre content suggests that the grain may have potential as an ingredient in health promoting foods. In this study, 29 healthy volunteers consumed extruded whole grain breakfast cereal made from Himalaya 292 (123 g) or a commercial hull-less barley (cv Torrens) (76 g) each supplying 50 g carbohydrate. Glycemic indices were 77 ± 13 (SEM) and 50 ± 9 for Torrens and Himalaya 292 breakfast cereals respectively (P = 0.004). On this basis, the Himalaya 292 cereal is a low glycemic index food. The glycemic load (the product of glycemic index and the available carbohydrate content of a 60 g serve divided by 100) of the new cultivar was 10.1 ± 1.8 compared to 25.3 ± 4.3 for the Torrens breakfast cereal (P < 0.001). The plasma insulin response to the test meal was 26% lower for Himalaya 292 than for Torrens (P = 0.023). The data confirm that Himalaya 292 may be of value in foods designed to assist in the prevention and management of diabetes.; R.A. King, M. Noakes, A.R. Bird, M.K. Morell and D.L. Topping; Copyright © 2008 Elsevier Ltd All rights reserved.

Glycemic index, glycemic load and endometrial cancer risk: results from the Australian National Endometrial Cancer study and an updated systematic review and meta-analysis

Nagle, C.M.; Olsen, C.M.; Ibiebele, T.I.; Spurdle, A.B.; Webb, P.M.; Australian National Endometrial Cancer Study Group; Australian Ovarian Cancer Study Group
Fonte: Springer-Verlag Publicador: Springer-Verlag
Tipo: Artigo de Revista Científica
Publicado em //2013 EN
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Purpose: The relationship between habitual consumption of foods with a high glycemic index (GI) and/or a diet with a high glycemic load (GL) and risk of endometrial cancer is uncertain, and relatively few studies have investigated these associations. The objectives of this study were to examine the association between GI/GL and risk of endometrial cancer using data from an Australian population-based case–control study and systematically review all the available evidence to quantify the magnitude of the association using meta-analysis. Methods: The case–control study included 1,290 women aged 18–79 years with newly diagnosed, histologically confirmed endometrial cancer and 1,436 population controls. Controls were selected to match the expected Australian state of residence and age distribution (in 5-year bands) of cases. For the systematic review, relevant studies were identified by searching PubMed and Embase databases through to July 2011. Random-effects models were used to calculate the summary risk estimates, overall and dose–response. Results: In our case–control study, we observed a modest positive association between high dietary GI (OR 1.43, 95 % CI 1.11–1.83) and risk of endometrial cancer, but no association with high dietary GL (OR 1.15...

Marcador in vitro da resposta glicêmica dos alimentos como ferramenta de auxílio à prescrição e avaliação de dietas; In vitro indicator of the glycemic response to foods as a tool for diet prescriptions and evaluation

CAPRILES, Vanessa Dias; GUERRA-MATIAS, Andréa Carvalheiro; ARÊAS, José Alfredo Gomes
Fonte: Pontifícia Universidade Católica de Campinas Publicador: Pontifícia Universidade Católica de Campinas
Tipo: Artigo de Revista Científica
POR
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As dietas de baixo índice glicêmico e baixa carga glicêmica têm sido associadas à redução do risco de doenças crônicas. Por esse motivo há um interesse crescente na sua aplicação para avaliação e orientação nutricional. No entanto, existem limitações quanto ao uso de dados publicados de índice glicêmico e carga glicêmica, pela variedade e formas de processamento dos alimentos vegetais existentes. Devido à dificuldade de realização de ensaios in vivo, uma vez que são custosos, trabalhosos, invasivos e necessitam de período considerável de experimentação, foram desenvolvidas metodologias in vitro que, a partir da velocidade de digestão dos carboidratos, permitem estimar o índice glicêmico dos alimentos de forma prática, simples e econômica. O presente trabalho apresenta o uso de um marcador in vitro, o índice de hidrólise, na estimativa do índice glicêmico e da carga glicêmica, o método mais empregado por pesquisadores brasileiros, visando à sua aplicação por profissionais da área de Nutrição. Os cálculos e as interpretações para estimativa do Índice glicêmico e da carga glicêmica são apresentados por meio de um exemplo prático com alguns alimentos brasileiros e com o grão de amaranto submetido a diferentes processamentos. Na ausência de dados referentes à resposta glicêmica do alimento de interesse...

The high glycemic index diet was an independent predictor to explain changes in agouti-related protein in obese adolescents

Molin Netto,Bárbara Dal; Landi Masquio,Deborah Cristina; Munhoz da Silveira Campos,Raquel; Lima Sanches,Priscila de; Campos Corgosinho,Flavia; Tock,Lian; Missae Oyama,Lila; Túlio de Mello,Marco; Tufik,Sergio; Dâmaso,Ana Raimunda
Fonte: Nutrición Hospitalaria Publicador: Nutrición Hospitalaria
Tipo: info:eu-repo/semantics/article; journal article; info:eu-repo/semantics/publishedVersion Formato: text/html; application/pdf
Publicado em 01/02/2014 ENG
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66.44%
The high glycemic index diet was an independent predictor to explain changes in agouti-related protein in obese adolescents. Background & Aims: The role of diet glycemic index (GI) in the control of orexigenic and anorexigenic factors of the energy balance is still not clear. The present study aimed to assess whether the habitual diet, according to different GI foods, exerts influence on regulation of energy balance markers and the effects of interdisciplinary intervention in obese adolescents. Methods: A total of 55 obese adolescents, aged from 14 to 19 years, were submited to one year of interdisciplinary therapy and were divided in two groups, according to the predominant dietary pattern of food intake: high-GI group (H-GI; n = 29) and moderate/low-GI group (M/L-GI; n = 26). Results: The concentration of orexigenic factor AgRP (p < 0.01), visceral fat (p=0.04) and visceral/subcutaneous ratio (p = 0.03) were higher in the group of H-GI when compared with M/L-GI group. Moreover, the habitual consumption of H-GI foods was an independent predictor to explain changes in AgRP concentrations. After one year of interdisciplinary therapy, the adolescents presented significant reductions in body weight, total body fat (%), visceral and subcutaneous fat and HOMA-IR...

Effect of the glycemic index on lipid oxidation and body composition

Lopes da Silva,M.ª V.; de Càssia Gonçalves Alfenas,R.
Fonte: Nutrición Hospitalaria Publicador: Nutrición Hospitalaria
Tipo: info:eu-repo/semantics/article; journal article; info:eu-repo/semantics/publishedVersion Formato: text/html; application/pdf
Publicado em 01/02/2011 ENG
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Several studies have been conducted to evaluate the effects of the consumption of the slowly absorbed carbohydrates in a low glycemic index (GI) diet on fat oxidation, in order to obtain dietetic treatment that can favor the achievement of an adequate body composition. Therefore, the purpose of this study was to analyze studies in which the role of low GI diets on body composition, with emphasis on fat oxidation. An internet search for articles, in English or Portuguese, published since 1995, was conducted using the following key words: glycemic index, glycemic load, glycaemic index, glycaemic load, body fat, body composition, fat oxidation. Papers that described animals or humans clinical trials were selected. Data were collected from Web of Science, Science Direct, Pubmed. It was verified that the results of the majority of the analyzed studies indicated that low GI diets lead to a lower insulin response, increasing body fat oxidation. These results indicate that the consumption of low GI diet can be an important strategy to be used for the prevention and control of obesity and chronic diseases associated to it.

Glycemic acute changes in type 2 diabetics caused by low and high glycemic index diets

Gonçalves Reis,C. E.; Dullius,J.
Fonte: Nutrición Hospitalaria Publicador: Nutrición Hospitalaria
Tipo: info:eu-repo/semantics/article; journal article; info:eu-repo/semantics/publishedVersion Formato: text/html; application/pdf
Publicado em 01/06/2011 ENG
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Introduction: Low-glycemic index diets may improve the glycemic control in type 2 diabetes but the debate over their effectiveness continues. Objectives: To test the effects of low-glycemic index diets on acute glycemic control (2 days) by measuring capillary blood glucose in patients with type 2 diabetes. Methods: This was a crossover randomized clinical trial with 12 type 2 diabetics which were randomly divided into 2 groups and targeted the following draft diets for low and high glycemic index (LGI and HGI) for 2 consecutive days in 2 consecutive weeks. Group 1 followed an LGI diet in week 1 and an HGI diet in week 2, group 2 adopted the contrary. They were oriented to maintain medication and lifestyle and to follow the recommendations. Measurements were made of glycemia capillaries in 2 days (fasting, before lunch, post-prandial lunch and before dinner) and one last in fasting on day 3. A food record during the days and the counting of carbohydrates meals was made. The software SigmaStat (version 2.03) was used, with a statistical significance criterion of p < 0.05. Results and discussion: The amount of carbohydrates ingested by the LGI group was lower (p < 0.01), showing that the adoption of this diet reduces the intake of carbohydrates...

Influence of the glycemic index and glycemic load of the diet in the glycemic control of diabetic children and teenagers

Queiroz,K. C.; Novato Silva,I.; de Cássia Gonçalves Alfenas,R.
Fonte: Nutrición Hospitalaria Publicador: Nutrición Hospitalaria
Tipo: info:eu-repo/semantics/article; journal article; info:eu-repo/semantics/publishedVersion Formato: text/html; application/pdf
Publicado em 01/04/2012 ENG
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Objective: Evaluate the influence of the glycemic index (GI) and glycemic load (GL) of the diet in the glycemic control of children and teenagers with type 1 diabetes mellitus (DM1). Methods: A total of 146 subjects, aged 7-19 years, monitored at the Division of Pediatric Endocrinology at the HC/UFMG participated in the study. The consumed diet was evaluated using a quantitative food frequency questionnaire previously validated and tested in a pilotproject. The GI of the participant´s diet was estimated according to the equation described by Wolever and Jenkins (1986). The GL was estimated using the equation proposed by Foster-Powell et al. (2002). The glycemic control was classified as good, intermediate or poor according to the average of two HbA1c values obtained six months prior to the dietary evaluation date. Results: Subjects that had good glycemic control consumed diets with significantly (Tukey test, p = 0.000) lower GI/GL (54.8 ± 2.7/118.3 ± 29.8) than the ones with intermediate (60.1 ± 3.8/142.5 ± 27.3) and poor (60.3 ± 4.1/153.7 ± 40.7) glycemic control. The diet consumed by 75.5% of diabetics with good glycemic control was classified as medium GL, suggesting that the consumption of medium GL diet may favor an adequate glycemic control. The low GI diet consumed by these participants also presented higher protein content...

Design and methods of the GLYNDIET study: assessing the role of glycemic index on weight loss and metabolic risk markers

Juanola-Falgarona,Martí; Ibarrola-Jurado,Núria; Salas-Salvadó,Jordi; Rabassa-Soler,Antoni; Bulló,Monica
Fonte: Nutrición Hospitalaria Publicador: Nutrición Hospitalaria
Tipo: info:eu-repo/semantics/article; journal article; info:eu-repo/semantics/publishedVersion Formato: text/html; application/pdf
Publicado em 01/04/2013 ENG
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Background: Glycemic index and/or glycemic load have been explored as an alternative for the prevention and/or management of obesity, cardiovascular disease, type 2 diabetes mellitus, and cancer. Objective: The purpose of the manuscript is to describe the design and methods used in the GLYNDIET Project, a study designed to simultaneously address the questions related to the exactly role of low glycaemic index carbohydrates has on weight loss. Methods: This study was designed as a 6-months randomized, parallel, controlled clinical trial aiming to evaluate the effect of the dietary glycemic index on weight-loss, satiety, glucose and insulin metabolism, lipid profile, inflammation and other emergent metabolic risk markers. Eligible subjects were community-dwelling men and women aged between 30 and 60 years, with a body mass index between 27 and 35 kg/m². Subjects were randomly assigned to three different dietary intervention groups (low glycemic index diet, high glycemic index diet or low-fat diet), that were isocaloric, and did not differ in the amount of dietary fibre. Monthly, study subjects were scheduled for control visits where anthropometry, blood pressure, dietary habits, satiety and physical activity were assessed. Blood, urine and subcutaneous adipose tissue samples were collected at baseline and at the end of the study to further molecular and biochemical measurements. Discussion: The GLYNDIET study was designed to determine if there is a greater effectiveness of a carbohydrate restricted diet with low glycemic index compared to an isocaloric diet with carbohydrates of high glycemic index or low-fat diet on weight loss in middle long-term.