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Doença periodontal grave em pacientes com e sem queixa de dor crônica crânio-facial: correlação dos aspectos clínicos com a análise quantitativa da substância P e do óxido nítrico do tecido gengival inflamado; Severe Periodontal Disease in patients with and without chronic complaint of craniofacial pain: correlation with clinical aspects with the quantitative analysis of substance P and nitric oxide of inflamed gingival tissue

Fabri, Gisele Maria Campos
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 13/12/2007 PT
Relevância na Pesquisa
46.56%
Objetivos: Avaliar a implicação da doença periodontal (DP) avançada, e da expressão da NOS e sP dos tecidos gengivais inflamados, na intensidade de dor e na qualidade de vida de pacientes com dor crônica crânio-facial. Casuística e Métodos: foram avaliados e tratados 20 pacientes com queixas de dores crônicas crânio-faciais e DP (Grupo de Estudo), comparativamente com 20 pacientes que tinham somente DP (Grupo Controle). Todos os pacientes receberam tratamento cirúrgico periodontal. A avaliação foi realizada pré e pós-tratamento periodontal (7, 30 e 180 dias). Instrumentos de avaliação: ficha clínica EDOF-HC, Escala Visual Analógica (EVA), questionário de dor McGill, Índices de Placa (IP), Sangramento (IS), Profundidade Clínica de Sondagem (PCS) e de Inserção (PCI); questionário de qualidade de vida WHOQOL-bref e análise imunohistoquímica para a expressão da óxido nítrico sintase (NOS) e da substância P do tecido gengival inflamado. A avaliação da dor foi realizada por investigador independente. Resultados: Os grupos apresentaram evolução clínica semelhante pelos parâmetros da DP: IP (p=0,0934), IS (p=0,8657), PCS (p=0,1728) e PCI (p=0,7406) nos três momentos avaliados. Houve redução da EVA no Grupo de Estudo aos 30 dias (p<0...

Disfunção temporomandibular e síndrome fibromiálgica: caracterização de amostra segundo critérios clínicos; Temporomandibular disorders and fibromyalgic syndrome: characterization of a sample according to clinical evaluation

Fujarra, Fábio José Condino
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 25/03/2008 PT
Relevância na Pesquisa
46.64%
Estudo transversal em que foram avaliados 48 doentes consecutivos (todas do gênero feminino) com diagnóstico de Síndrome Fibromiálgica (SFM). A idade média das doentes foi de 46,3 anos (±8,7, 23-59 anos). A avaliação clínica constou do questionário RDC/TMD e de avaliação em dor orofacial (EDOF-HC). Quanto à queixa principal, 26 doentes (54,2%) apresentaram dor na face, 18 (37,5%) dor na face associada a alguma queixa oral, uma (2,1%) teve queixa de estalidos na articulação temporomandibular, uma (2,1%) teve queixa exclusivamente oral e duas doentes (4,2%) não tiveram qualquer queixa. Em relação à presença de dor generalizada, as 48 doentes avaliadas tinham dores no corpo. A dor na face esteve presente em 44 doentes (91,7%). Quarenta e quatro doentes (91,7%) apresentaram cefaléia. Otalgia esteve presente em 19 doentes (39,6%). A dor na face se iniciou antes da dor no corpo em 17 doentes (38,6%), depois em 20 (45,5%), simultaneamente em seis doentes (13,6%) e uma doente (2,1%) não soube definir esta relação temporal. Os sintomas orofaciais melhoraram com o uso de medicação para tratamento da SFM em 24 doentes (54,5%), e três (6,8%) não souberam responder. Quanto à abertura bucal voluntária sem dor a média foi de 32...

Avaliação e tratamento de pacientes com dor facial atípica através da estimulação magnética transcraniana repetitiva; Assessment and treatment of patients with atypical facial pain patients that underwent repetitive transcranial magnetic stimulation

Galhardoni, Ricardo
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 30/10/2014 PT
Relevância na Pesquisa
66.53%
Dor facial atípica (DFA) é uma condição álgica crônica destacada pela etiopatogenia ainda desconhecida e pela característica rebelde aos tratamentos vigentes. O objetivo deste estudo é avaliar o limiar e padrões de excitabilidade cortical de doentes com DFA através de Estimulação Magnética Transcraniana (EMT) e compará-los a controles saudáveis, além de avaliar a eficácia terapêutica da EMT repetitiva (EMTr) ativa em doentes com DFA comparados à EMTr placebo. Durante o período de março de 2010 a dezembro de 2013 foram avaliados 29 doentes com DFA - os quais preencheram os critérios segundo a classificação proposta pela Associação Internacional de Cefaleia (2004) - e 28 controles saudáveis. A avaliação foi iniciada com a investigação da excitabilidade cortical bilateral. Em seguida, os doentes foram aleatorizados em dois grupos (ativo e placebo) para o tratamento com EMTr sobre o córtex motor primário na área de representação da face, esquematizado da seguinte forma: cinco sessões consecutivas para a fase de indução, e uma sessão semanal (pelo período de oito semanas) para a de manutenção; frequência excitatória de 10Hz; 80% do limiar motor de repouso; e 3000 pulsos no total por sessão. Os doentes foram avaliados quanto às características dolorosas no momento basal...

Sleep bruxism: Clinical aspects and characteristics in patients with and without chronic orofacial pain

Camparis, Cinara Maria; Siqueira, J. T T
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Artigo de Revista Científica Formato: 188-193
ENG
Relevância na Pesquisa
56.34%
Objective. Evaluation of long-standing sleep bruxism (SB) patients. Study Design. Descriptive study. Results. One hundred subjects with SB (80 women and 20 men, mean age: 36.1±11.3 years) were evaluated according to the RDC/TMD and a pain questionnaire (EDOF-HC). The patients were divided into 2 groups: Group A-without (30.0%) and Group B-with orofacial pain (70.0%). AM stiffness: 36.4% in Group A and 88.6% in Group B; mean pain duration: 6.92 years; mean intensity of pain: 4.33 (VAS); quality of pain: tightness/pressure (84,3%); 95.7% of Group B had myofascial pain. Depression and somatization levels were different between the groups (p = 0.001). Higher frequency of depression was found with body pain or presence of comorbidities. Conclusion. The data presented in this study showed statistical differences between long-standing bruxism without and with chronic facial pain; the two questionnaires allowed interaction between the chief complaint and the clinical findings; depression levels increased with pain in several regions of the body. © 2006 Elsevier Inc. All rights reserved.

Facial pain associated with fibromyalgia can be marked by abnormal neuromuscular control: A cross-sectional study

Gui, Maísa Soares; Pedroni, Cristiane Rodrigues; Aquino, Luana M. Martins; Pimentel, Marcele Jardim; Alves, Marcelo Correa; Rossini, Sueli; Reimão, Rubens; Berzin, Fausto; Marques, Amélia Pasqual; Rizzatti-Barbosa, Célia Marisa
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Artigo de Revista Científica Formato: 1092-1101
ENG
Relevância na Pesquisa
66.54%
Background. Temporomandibular disorder (TMD) development in fibromyalgia syndrome (FMS) is not yet fully understood, but altered neuromuscular control in FMS may play a role in triggering TMD. Objective. The purpose of this study was to verify the association between neuromuscular control and chronic facial pain in groups of patients with FMS and TMD. Design. A cross-sectional study was conducted. Methods. This study involved an analysis of facial pain and electromyographic activity of the masticatory muscles in patients with FMS (n=27) and TMD (n=28). All participants were evaluated according to Research Diagnostic Criteria for Temporomandibular Disorders and surface electromyography (SEMG). Myoelectric signal calculations were performed using the root mean square and median frequency of signals. Results. The data revealed premature interruption of masticatory muscle contraction in both patient groups, but a significant correlation also was found between higher median frequency values and increased facial pain. This correlation probably was related to FMS because it was not found in patients with TMD only. Facial pain and increased SEMG activity during mandibular rest also were positively correlated. Limitations. Temporal conclusions cannot be drawn from the study. Also...

Estudo da dor facial e da atividade eletromiográfica de músculos mastigatórios em portadores de fibromialgia e distúrbios do sono, com diagnóstico de disfunção temporomandibular; Facial pain evaluation and electromyography activity of masticatory muscles in fibromyalgia and sleep disorders patients with diagnosis of temporomandibular disorder

Maísa Soares Gui
Fonte: Biblioteca Digital da Unicamp Publicador: Biblioteca Digital da Unicamp
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 25/03/2011 PT
Relevância na Pesquisa
46.65%
A prevalência e a coexistência das Disfunções Temporomandibulares (DTM) na Síndrome Fibromiálgica (SFM) têm sido frequentemente estudadas na literatura, no entanto os estudos que correlacionem as duas condições de dor crônica e a eletromiografia são escassos. Além disso, os distúrbios do sono representam um fator perpetuador da dor na SFM. Desse modo realizou-se uma revisão bibliográfica buscando conhecer a relação entre os distúrbios do sono e os sintomas da fibromialgia e sua importância na avaliação dos fibromiálgicos por meio de levantamento bibliográfico do período de 1990-2009. A literatura demonstrou uma alta prevalência de distúrbios do sono em pacientes portadores de fibromialgia e uma relevante relação entre as anormalidades no padrão do sono e o sintoma da dor crônica. Assim, com o objetivo de avaliar a dor, a qualidade do sono e de vida e a atividade eletromiográfica de músculos mastigatórios, bem como a presença de DTM em portadoras da SFM, caracterizando a dor facial destes pacientes, foi realizado primeiramente um estudo piloto a fim de refinar a metodologia e averiguar as hipóteses formuladas, no qual dez mulheres portadoras de SFM participaram, e concluímos preliminarmente que há associação entre o aumento da dor facial e o aumento da atividade elétrica de músculos mastigatórios na SFM...

Estudo de fatores de cronicidade das disfunções temporomandibulares; Study of temporomandibular disorders chronicity factors

Maisa Soares Gui Demase
Fonte: Biblioteca Digital da Unicamp Publicador: Biblioteca Digital da Unicamp
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 09/09/2014 PT
Relevância na Pesquisa
46.63%
A dor persistente relacionada às disfunções temporomandibulares (DTM) é reconhecida como a terceira condição de dor crônica mais prevalente em todo o mundo. Todavia, os fatores envolvidos na transição da fase aguda para a fase crônica ainda permanecem incertos. Além disso, há subgrupos de pacientes com DTM que são refratários ao tratamento. Um modelo heurístico de influências causais desta disfunção propôs que dois principais fenótipos intermediários: sofrimento psicológico e de amplificação da dor (hiperalgesia e alodinia), contribuiriam para o aparecimento e persistência das DTM. Além disso, no atendimento ao paciente crônico com DTM é difícil determinar especificamente o que pode ou não estar relacionado à dor para cada paciente individualmente. O conhecimento dos fatores persistentes e abordagens de tratamento que enfatizem a sua flexibilidade e que satisfaçam as necessidades individuais destes pacientes podem representar uma nova direção na pesquisa para o tratamento da dor crônica associada à DTM. Desse modo, o objetivo deste trabalho foi investigar fatores (de sofrimento psicológico e de amplificação da dor) relacionados ao processo de cronificação da dor facial nas DTM. Para tanto, após o levantamento bibliográfico elaborado no primeiro artigo...

Findings of jaw function and pain in temporomandibular disorder associated to localized and widespread pain = : Achados de função mandibular e dor na disfunção temporomandibular associada à dor localizada e generalizada; Achados de função mandibular e dor na disfunção temporomandibular associada à dor localizada e generalizada

Marta Cristina da Silva Gama
Fonte: Biblioteca Digital da Unicamp Publicador: Biblioteca Digital da Unicamp
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 24/11/2014 PT
Relevância na Pesquisa
56.64%
A Disfunção Temporomandibular (DTM) é uma condição de dor músculo-esquelética heterogênea. Recentemente, tem sido sugerida a distinção entre disfunção temporomandibular com dor localizada ou generalizada. O presente estudo teve como objetivo revisar o conhecimento atual sobre os achados clínicos relativos a avaliação funcional da mandíbula em pacientes com DTM, e avaliar a função mandibular e as características de dor facial entre subgrupos de pacientes com DTM, os quais foram classificados de acordo com a presença de dor localizada (DL) ou de dor generalizada (DG). Foram realizados dois estudos transversais e uma revisão da literatura. O questionário autoaplicável e os procedimentos de exame clínico do RDC / TMD foram aplicados em populações do Brasil (BR) e dos Estados Unidos da América (EUA). Os participantes foram classificados como controles sem queixas de DTM (BR=37, EUA=2,700), pacientes com DTM/DL (BR=43, EUA=463) e pacientes com DTM/DG (BR=33, EUA=569). Estes três grupos foram comparados em relação a cada medida de interesse, as quais foram obtidas a partir da avaliação clínica da dor facial e da função mandibular e de perguntas de auto-relato sobre dor facial, limitação funcional e hábitos parafuncionais. Além do exame clínico facial...

Percutaneous radiofrequency rhizotomy and neurovascular decompression of the trigeminal nerve for the treatment of facial pain

Teixeira,Manoel J.; Siqueira,Silvia R.D.T.; Almeida,Gilberto M.
Fonte: Academia Brasileira de Neurologia - ABNEURO Publicador: Academia Brasileira de Neurologia - ABNEURO
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2006 EN
Relevância na Pesquisa
66.56%
OBJECTIVE: To determine the outcomes of 354 radiofrequency rhizotomies and 21 neurovascular decompressions performed as treatment for 367 facial pain patients (290 idiopathic trigeminal neuralgia, 52 symptomatic trigeminal neuralgia, 16 atypical facial pain, 9 post-herpetic neuralgia). METHOD: Clinical findings and surgery success rate were considered for evaluation. A scale of success rate was determined to classify patients, which considered pain relief and functional/sensorial deficits. RESULTS: Radiofrequency rhizotomy was performed in 273 patients with idiopathic trigeminal neuralgia and in all other patients, except for trigeminal neuropathy; neurovascular decompression was performed in 18 idiopathic trigeminal neuralgia patients; 100% idiopathic trigeminal neuralgia, 96.2% symptomatic trigeminal neuralgia, 37.5% atypical facial pain and 88.9% post-herpetic neuralgia had pain relief. CONCLUSION: Both techniques for idiopathic trigeminal neuralgia are usefull. Radiofrequency rhizotomy was also efficient to treat symptomatic facial pain, and post-herpetic facial pain, but is not a good technique for atypical facial pain.

Diferential diagnosis in atypical facial pain: a clinical study

Nóbrega,José Cláudio Marinho; Siqueira,Silvia Regina Dowgan Tesseroli de; Siqueira,José Tadeu Tesseroli de; Teixeira,Manoel Jacobsen
Fonte: Academia Brasileira de Neurologia - ABNEURO Publicador: Academia Brasileira de Neurologia - ABNEURO
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/2007 EN
Relevância na Pesquisa
66.5%
OBJETIVE: To evaluate a sample of patients with atypical facial pain (AFP) in comparison to patients with symptomatic facial pain (SFP). METHOD: 41 patients with previous diagnostic of AFP were submitted to a standardized evaluation protocol, by a multidisciplinary pain team. RESULTS: 21 (51.2%) were considered AFP and 20 (48.8%) (SFP) received the following diagnosis: 8 (40.0%) had temporomandibular disorders (TMD); 3 (15.0%) had TMD associated to systemic disease (fibromyalgia, systemic erythematosus lupus); 4 (20.0%) had neuropathy after ear, nose and throat (ENT) surgery for petroclival tumor; 2 (10.0%) had Wallenberg syndrome; 1 (5.0%) had intracranial tumor; 1 (5.0%) had oral cancer (epidermoid carcinoma), and 1 (5.0%) had burning mouth syndrome (BMS) associated to fibromyalgia. Spontaneous descriptors of pain were not different between AFP and SFP groups (p=0.82). Allodynia was frequent in SFP (p=0.05) and emotion was the triggering factor most prevalent in AFP (p=0.06). AFP patients had more traumatic events previously to pain (p=0.001). CONCLUSION: AFP patients had more: a) traumatic events previously to pain onset, and b) emotions as a triggering factor for pain. These data support the need of trained health professionals in multidisciplinary groups for the accurate diagnosis and treatment of these patients.

Quantitative sensory testing in trigeminal traumatic neuropathic pain and persistent idiopathic facial pain

Siqueira,Silvia R. D. T. de; Siviero,Mariana; Alvarez,Fábio K.; Teixeira,Manoel J.; Siqueira,José T. T. de
Fonte: Academia Brasileira de Neurologia - ABNEURO Publicador: Academia Brasileira de Neurologia - ABNEURO
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/03/2013 EN
Relevância na Pesquisa
66.46%
The objective of this article was to investigate, with a systematic protocol of quantitative sensory testing, patients with persistent idiopathic facial pain (PIFP) and others with trigeminal traumatic neuropathic pain (TTN) compared to controls. Thirty patients with PIFP, 19 with TTN, and 30 controls were evaluated on subjective numbness and dysesthesia and with a systematic protocol of quantitative sensory testing for thermal evaluation (cold and warm), mechanical detection (touch and pinpricks for mechanical pain), superficial pain thresholds, and corneal reflex. We found that PIFP and TTN had numbness and dysesthesia higher than controls (p<0.001 and p=0.003), and that in both of them mechanical pain by pinpricks detection was abnormal intra and extra orally at the mandibular branch (p<0.001). Cold, warm, and tactile detections and pain thresholds were similar among the groups. Corneal reflex was abnormal in TTN (p=0.005). This study supports neuropathic mechanisms involving pain processing in PIFP and that the criterion on absence of sensorial variations in PIFP should be revised.

Endoscopic sinus surgery in individuals with facial pain due to chronic maxillary sinusitis ? a functional controlled study

Sanges,Giuseppe; Gamerra,Mario; Sorrentino,Gerardo; Luca,Roberto De; Merone,Maddalena; Feleppa,Michele; Bigal,Marcelo Eduardo
Fonte: Academia Brasileira de Neurologia - ABNEURO Publicador: Academia Brasileira de Neurologia - ABNEURO
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/08/2014 EN
Relevância na Pesquisa
66.31%
Objective: To measure the intra-sinus pressure and the maxillary sinus functional efficiency (MSFE) in individuals with chronic facial pain after conservative or conventional endoscopic maxillary surgery, as well as in controls. Method: Sinus manometry was performed 5 times during inhalation. Results: The resemblance of pressure values comparing those treated with minimally invasive surgery and controls was remarkable, while traditional surgery significantly decreased intrasinusal pressures. The MSFE was 100% in the three tested times for controls, close to that in those submitted to minimally invasive surgery (98.3%, 98.8%, and 98.0%) and significantly impaired after conventional surgery (48.8%, 52.1%, 48.5 %, p<0.01). All patients submitted to minimally invasive surgery remained pain-free after three months of surgery, relative to 46.7% of the submitted to conventional surgery (p<0.05). Conclusion: Minimally invasive sinus surgery is associated with functionality of the chambers that resemble what is found in normal individuals.

Facial pain of cardiac origin: a case report

Franco,Ana Carolina de Oliveira; Siqueira,José Tadeu Tesseroli de; Mansur,Alfredo José
Fonte: Associação Paulista de Medicina - APM Publicador: Associação Paulista de Medicina - APM
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2006 EN
Relevância na Pesquisa
66.46%
CONTEXT: Cardiac pain may radiate to the face and lead patients to seek dental care. Dentists may contribute towards the diagnosing of ischemic heart disease and thus refer patients for cardiological evaluation. CASE REPORT: A 50-year-old female patient was referred to a dentist for evaluation of a suspected temporomandibular disorder after repeated visits to medical emergency departments due to excruciating facial and left temporal pain associated with exertion. The pain would start in the chest and radiate to the neck, face and left temporal region. The patient’s chief complaint was the facial pain; hence, she sought dental care. The dental examination revealed an edentulous upper jaw and partially edentulous lower jaw with full upper prosthetic set of teeth and decreased vertical dimension. X-ray of facial bones did not reveal any bone abnormalities. A diagnosis of temporomandibular disorder was made. However, she was referred for cardiological evaluation, since her pain was starting in the chest and because she had a past medical history of surgical treatment for coronary artery disease. A diagnosis of angina pectoris was made, the therapeutic regimen was optimized and her angina was brought under control.

Quality of life in temporomandibular disorder patients with localized and widespread pain

Gui,Maísa Soares; Pimentel,Marcele Jardim; Gama,Marta Cristina da Silva; Ambrosano,Glaucia Maria Bovi; Barbosa,Célia Marisa Rizzatti
Fonte: Faculdade de Odontologia de Piracicaba - UNICAMP Publicador: Faculdade de Odontologia de Piracicaba - UNICAMP
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/09/2014 EN
Relevância na Pesquisa
56.3%
AIM: To compare temporomandibular (TMD) subgroups classified according to the presence of localized pain (LP) or widespread pain (WP) in order to assess the quality of life domains and verify which components affect most the functional capacity of facial pain patients. METHODS: A cross-sectional study was conducted and the Short Form-36 Health Survey was applied in order to assess quality of life. Thirty-nine TMD/WP patients, 37 TMD/LP patients and 40 subjects free of TMD complaints were evaluated. RESULTS: TMD/WP patients differed significantly from healthy controls in all SF-36 components and TMD/LP patients ranked between them. It was also observed that patients with bodily pain and TMD with WP are respectively, 4.16 and 49.42 times more likely to have low functional capacity. CONCLUSIONS: Functional capacity in TMD subgroups was only affected by the presence of bodily pain and WP. These patients feature high chance of low functional capacity. Furthermore, TMD patients with localized and widespread pain share role-emotional impairments.

Temporomandibular disorder pain improvement with acupuncture: preliminary longitudinal descriptive study

Camargo,Bruna Angeleli Bueno de; Grillo,Cássia Maria; Sousa,Maria da Luz Rosário de
Fonte: Sociedade Brasileira para o Estudo da Dor Publicador: Sociedade Brasileira para o Estudo da Dor
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/09/2014 EN
Relevância na Pesquisa
56.32%
BACKGROUND AND OBJECTIVES: Acupuncture is a therapeutic method widely used to manage pain. Temporomandibular disorders have symptoms such as facial pain, pain in temporomandibular region and in masticatory muscles. This study aimed at describing the results obtained in temporomandibular disorder pain intensity improvement in patients treated in a public service with a minimum number of three acupuncture sessions. METHODS: This is a descriptive study with patients with temporomandibular disorders treated in the Dentistry Specialties Center I of the city of Piracicaba (SP) in the period from September 2010 to October 2011. Sample was made up of 31 patients of both genders, aged between 14 and 68 years. Pain was measured by the visual analog scale (VAS), called initial VAS (pre-treatment) and final VAS (post-treatment), respectively in the beginning and end of the acupuncture session. Each patient was submitted to three 20-minute sessions, once a week. RESULTS: Pain was absent (VAS=0) in 67.7% of patients who had pain intensity improvement with iVAS in the first session higher (6.10±2.64) than fVAS in the third session (1.16±1.98). CONCLUSION: With a minimum of three weekly acupuncture sessions it was possible to control temporomandibular disorder pain regardless of the level of initial pain. Its use could contribute to enhance the treatment of such patients in the public service for being a low cost and easy to apply therapy.

Monoamines in the brain cerebrospinal fluid of facial pain patients.

Bouckoms, A. J.; Sweet, W. H.; Poletti, C.; Lavori, P.; Carr, D.; Matson, W.; Gamache, P.; Aronin, N.
Fonte: American Dental Society of Anesthesiology Publicador: American Dental Society of Anesthesiology
Tipo: Artigo de Revista Científica
Publicado em //1992 EN
Relevância na Pesquisa
46.5%
The purpose of the study was to assay monoamines in cerebrospinal fluid (CSF) obtained from the trigeminal cistern of 64 patients with intractable facial pain. The CSF was analyzed for homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA), and 3-methoxy-4-hydroxyphenylglycol (MHPG), end-product markers of activity for the dopamine, serotonin, and norepinephrine systems, respectively. HVA averaged 121 ng/mL in these facial pain patients, compared to 150 to 550 ng/mL in 10 studies of ventricular brain CSF in assorted psychiatric and pain patients. 5-HIAA averaged 29 to ng/mL in our facial pain patients compared to 60 to 120 ng/mL in nine studies of ventricular brain CSF in assorted psychiatric and neurological patients. Trigeminal cistern CSF MHPG averaged 9 ng/mL, similar to the range of 13 studies of lumbar CSF of assorted psychiatric and pain diagnoses. These results indicate that (1) the electrochemical detection method provides a unique way of accurately measuring nanogram concentrations of multiple monoamines in a little as 0.25 mL of CSF; (2) trigeminal cistern and posterior fossa brain CSF monoamine metabolites reflect a different profile of dopaminergic and serotonergic functioning in these facial pain patients from that previously reported with lumbar CSF measurements of other patients; and (3) trigeminal sensory ganglion or brain dopamine and serotonin systems may be concomitantly dysfunctional in intractable facial pain.

Neurologic Aspects of Chronic Facial Pain

Maciewicz, Raymond
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em //1990 EN
Relevância na Pesquisa
56.31%
Chronic facial pain can result from neuropathic changes associated with deafferentation. The pattern of deep afferent convergence on trigeminal cells may also relate to the pathophysiology of chronic facial pain disorders.

Risk factors for onset of chronic oro-facial pain – Results of the North Cheshire oro-facial pain prospective population study

Aggarwal, Vishal R.; Macfarlane, Gary J.; Farragher, Tracey M.; McBeth, John
Fonte: Elsevier/North-Holland Publicador: Elsevier/North-Holland
Tipo: Artigo de Revista Científica
Publicado em /05/2010 EN
Relevância na Pesquisa
46.59%
Due to the cross-sectional nature of previous studies, whether mechanical factors predict the onset of Chronic oro-facial pain remains unclear. Aims of the current study were to test the hypotheses that self-reported mechanical factors would predict onset of Chronic oro-facial pain and that any observed relationship would be independent of the confounding effects of psychosocial factors and reporting of other unexplained symptoms. About 1735 subjects who had completed a baseline questionnaire were assessed at 2 year follow-up for the presence of Chronic oro-facial pain, psychosocial factors (anxiety and depression, illness behaviour, life stressors and reporting of somatic symptoms), mechanical dysfunction (facial trauma, grinding, phantom bite and missing teeth) and reporting of other unexplained symptoms (chronic widespread pain, irritable bowel syndrome and chronic fatigue). About 1329 subjects returned completed questionnaires (adjusted response rate 87%). About 56 (5%) reported new episodes of Chronic oro-facial pain at follow-up. Univariate analyses showed that age, gender, reporting of other unexplained symptoms, psychosocial factors and two self-report mechanical factors predicted the onset of Chronic oro-facial pain. However multivariate analysis showed that mechanical factors did not independently predict onset. The strongest predictors were health anxiety (Relative Risk (RR) 2.8...

Clinical study of patients with persistent orofacial pain

Siqueira,José Tadeu Tesseroli de; Lin,Hui  Ching; Nasri,Cibele; Siqueira,Silvia Regina Dowgan Tesseroli de; Teixeira,Manoel Jacobsen; Heir,Gary; Valle,Luís Biela S.
Fonte: Academia Brasileira de Neurologia - ABNEURO Publicador: Academia Brasileira de Neurologia - ABNEURO
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2004 EN
Relevância na Pesquisa
56.41%
OBJETIVE: To evaluate a sample of patients with persistent facial pain unresponsive to prior treatments. METHODS: Hospital records of 26 patients with persistent facial pain were reviewed (20 female and 6 male). RESULTS: Patients were classified into three groups according to their presenting symptoms: a)Group I, eight patients (30.7%) with severe, diffuse pain at the face, teeth or head; b)Group II, eight patients (30.7%) with chronic non-myofascial pain and; c)Group III, ten patients with chronic myofascial pain (38.4%). We find 11 different diagnoses among the 26 patients: pulpitis(7), leukemia(1), oropharyngeal tumor(1), atypical odontalgia(1), Eagle's syndrome(1), trigeminal neuralgia(4), continuous neuralgia(1), temporomandibular disorders (9), fibromyalgia (2), tension-type headache(1), conversion hysteria(2). After the treatment program all patients had a six-month follow-up period with pain relief, except the patient with tumor. CONCLUSION: The wide variability of orofacial pain diagnosis (benign to life-threatening diseases) indicates the necessity to reevaluate patients presenting recurrent pain that is refractory to the usual treatments.

Quality of life in temporomandibular disorder patients with localized and widespread pain

Gui, Maísa Soares; Pimentel, Marcele Jardim; Gama, Marta Cristina da Silva; Ambrosano, Glaucia Maria Bovi; Barbosa, Célia Marisa Rizzatti
Fonte: UNICAMP/FOP Publicador: UNICAMP/FOP
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ;
Publicado em 30/12/2010 POR
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56.3%
Aim: To compare temporomandibular (TMD) subgroups classified according to the presence of localized pain (LP) or widespread pain (WP) in order to assess the quality of life domains and verify which components affect most the functional capacity of facial pain patients. Methods: A cross-sectional study was conducted and the Short Form-36 Health Survey was applied in order to assess quality of life. Thirty-nine TMD/WP patients, 37 TMD/LP patients and 40 subjects free of TMD complaints were evaluated. Results: TMD/WP patients differed significantly from healthy controls in all SF-36 components and TMD/LP patients ranked between them. It was also observed that patients with bodily pain and TMD with WP are respectively, 4.16 and 49.42 times more likely to have low functional capacity. Conclusions: Functional capacity in TMD subgroups was only affected by the presence of bodily pain and WP. These patients feature high chance of low functional capacity. Furthermore, TMD patients with localized and widespread pain share roleemotional impairments.