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Can we derive occupation from enthesopathies? Lessons from the Coimbra Identified Skeletal Collection

Umbelino, Cláudia; Cunha, Eugénia
Fonte: Universidade de Coimbra. Departamento de Antropologia. CIAS Publicador: Universidade de Coimbra. Departamento de Antropologia. CIAS
Tipo: Conferência ou Objeto de Conferência
ENG
Relevância na Pesquisa
27.59%

The Coimbra Workshop in Musculoskeletal Stress Markers (MSM): an annotated review

Santos, Ana Luísa; Alves-Cardoso, Francisca; Assis, Sandra; Villotte, Sébastien
Fonte: Centro de Investigação em Antropologia e Saúde (CIAS) Publicador: Centro de Investigação em Antropologia e Saúde (CIAS)
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
17.59%
The Workshop in Musculoskeletal Stress Markers (MSM): limitations and achievements in the reconstruction of past activity patterns, was held at the University of Coimbra, in Portugal (2nd – 3rd July 2009). The chief goal of the organizing committee was to provide a productive environment where researchers could discuss the methodologies and terminology employed for the study of MSM as well as assessing how well these enthesopathies serve as markers of occupational stress. The Workshop was organized in three major sessions, each one introduced by a keynote lecture: (1) Methodological issues; (2) MSM studies of archaeological samples and Identified Skeletal Collections; and (3) The multifactorial etiology of enthesopathies. The meeting was concluded with a Plenary Session where two annotators discussed the presentations; this was followed by a general discussion and the formation of three working groups focused on the topics of Methods, Terminology, and Occupations. Details of the Workshop and the presentations presented are available for download at http://www.uc.pt/en/cia/msm/. A blog (http://coimbraworkshopmsm.blogspot. com/) was created to facilitate communications about individual experiences and to share knowledge among researchers in this field. We hope that this Workshop will help to standardize methodologies and terminology and promote the creation of a more integrated scientific approach to future studies of MSM.; A Universidade de Coimbra acolheu...

Enterramentos em fossa no distrito de Beja : práticas funerárias e estudo dos vestígios osteológicos da Pré-história recente

Pereira, Tânia Filipa da Eira
Fonte: Universidade de Coimbra Publicador: Universidade de Coimbra
Tipo: Dissertação de Mestrado
POR
Relevância na Pesquisa
16.88%
Os contextos funerários da Pré-história Recente do Alentejo têm vindo a ser estudados e debatidos com base nos novos dados que têm surgido devido aos trabalhos de Arqueologia de salvamento, principalmente relativos à grande quantidade de estruturas em negativo (fossas, hipogeus e fossos). O objectivo da presente dissertação é perceber mais acerca das comunidades que frequentaram os locais de enterramento, através do estudo dos mortos, dos seus vestígios osteológicos e das práticas funerárias. A amostra é composta pelos indivíduos exumados de estruturas em fossa de quatro sítios arqueológicos do distrito de Beja. São estes Monte do Vale do Ouro 2 (Ferreira do Alentejo), Ribeira de S. Domingos 1 (Brinches), Misericórdia 1 (Beringel) e Alto de Brinches 3 (São Salvador), datados do Calcolítico e da Idade do Bronze. A amostra óssea encontra-se amplamente afectada por factores tafonómicos como raízes, fungos, e concreções de calcário o que, na maior parte das vezes, dificultou o seu estudo. Algumas das estruturas contêm enterramentos múltiplos, enquanto outras evidenciam enterramentos individuais. A posição de inumação varia entre o decúbito lateral (esquerdo e direito), decúbito dorsal e decúbito ventral e as orientações de enterramento são diversas...

Nas cinzas jazem engendros da morte, reflexos de vidas de outrora : As cremações pré-históricas dos Perdigões

Pereira, Daniela
Fonte: Universidade de Coimbra Publicador: Universidade de Coimbra
Tipo: Dissertação de Mestrado
POR
Relevância na Pesquisa
16.88%
O presente estudo retrata a investigação feita sob uma amostra de ossos humanos cremados, exumados no recinto pré-histórico dos Perdigões -Reguengos de Monsaraz, Évora. A cronologia do material ósseo insere-o no período Calcolítico final. Os remanescentes analisados provêm de dois depósitos de inumação secundária (ambiente 1 e cista), situados no centro do recinto (sector Q), ainda não totalmente escavados. Os fragmentos humanos recolhidos (36742,64gr do ambiente 1 e 1856,76gr da cista) correspondem a um número mínimo de 90 indivíduos para o ambiente 1, 72 adultos e 18 não adultos, e 8 para a cista, 5 adultos e 3 não adultos. No âmbito da Antropologia funerária, a análise da coloração e do padrão de fratura presentes no osso permitiu a retirada de importantes conclusões sobre a prática funerária. A maioria dos remanescentes observados, adultos e não adultos, encontravase completamente calcinados, exibindo a cor branca. As temperaturas alcançadas durante a combustão terão sido elevadas (> 600º). O padrão de fratura registado indica que esta prática incluiu indivíduos em diferentes estados de decomposição. A fragmentação da amostra condicionou deveras o estudo paleodemográfico e patológico. A diagnose sexual testemunha um indivíduo do sexo masculino e um feminino. Entre as patologias e lesões possíveis de identificar destacam-se alteração de entese...

Os sepultados de Jabuticabeira II, SC - insights e inferências sobre padrões fenotípicos, análise de modo de vida e organização social através de marcadores de estresse músculo-esqueletal; The buried people of Jabuticabeira II, SC - insights and inferences about phenotypic patterns, way of life analysis and social organization by musculo-skeletal markers

Abbas, Adam Reiad
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 17/04/2013 PT
Relevância na Pesquisa
16.88%
Os marcadores de estresse músculo-esqueletal (MSMs), assim denominados, surgem pela primeira vez em 1995 no trabalho pioneiro de Hawkey e Merbs. De lá pra cá, diversos estudos se prestaram a aprimorar o método desenvolvido pelos pesquisadores e, ainda, associar de maneira mais concreta os graus de desenvolvimento de enteses a atividades desenvolvidas ao longo da vida de um indivíduo. Sob tais circunstâncias, buscamos neste trabalho a verificação da implementação de uma metodologia de análise revisada, testada e aprimorada dos marcadores de estresse músculo-esqueletal e a possibilidade de correlação entre os graus de desenvolvimento das enteses estudadas com as possíveis atividades desenvolvidas pelos indivíduos analisados, provenientes do sambaqui costeiro catarinense Jabuticabeira II (JAB-II). A escolha pela análise dos remanescentes ósseos deste sítio decorreu da vasta informação disponível em relação aos mesmos e ao sítio em si, provindos de outros trabalhos desenvolvidos previamente. Assim, estudos de paleopatologia e arqueologia possibilitaram melhores interpretações dos resultados obtidos pelas análises de MSMs. Neste trabalho procuramos adaptar a metodologia desenvolvida por Mariotti (2004,2007) para amostras antigas (mais de 2000 anos atrás) e de baixa conservação. Além disso...

Rapidly progressive sacroiliitis in a patient with lymphocytic lymphoma.

Cohen, M R; Carrera, G E; Lundberg, J
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /03/1993 EN
Relevância na Pesquisa
16.88%
Rheumatological manifestations may develop as paraneoplastic syndromes in patients with malignancy. Sacroiliitis and spondyloarthropathy have not, however, been previously associated with cancer. The case is described of a patient with a stage IV diffuse well differentiated lymphocytic lymphoma who developed concomitant sacroiliitis and enthesopathies with rapid progression following the diagnosis of malignancy.

Fibrocartilage in tendons and ligaments — an adaptation to compressive load

BENJAMIN, M. ; RALPHS, J. R.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /11/1998 EN
Relevância na Pesquisa
16.88%
Where tendons and ligaments are subject to compression, they are frequently fibrocartilaginous. This occurs at 2 principal sites: where tendons (and sometimes ligaments) wrap around bony or fibrous pulleys, and in the region where they attach to bone, i.e. at their entheses. Wrap-around tendons are most characteristic of the limbs and are commonly wider at their point of bony contact so that the pressure is reduced. The most fibrocartilaginous tendons are heavily loaded and permanently bent around their pulleys. There is often pronounced interweaving of collagen fibres that prevents the tendons from splaying apart under compression. The fibrocartilage can be located within fascicles, or in endo- or epitenon (where it may protect blood vessels from compression or allow fascicles to slide). Fibrocartilage cells are commonly packed with intermediate filaments which could be involved in transducing mechanical load. The ECM often contains aggrecan which allows the tendon to imbibe water and withstand compression. Type II collagen may also be present, particularly in tendons that are heavily loaded. Fibrocartilage is a dynamic tissue that disappears when the tendons are rerouted surgically and can be maintained in vitro when discs of tendon are compressed. Finite element analyses provide a good correlation between its distribution and levels of compressive stress...

Diffuse idiopathic skeletal hyperostosis in ancient clergymen

Verlaan, J. J.; Oner, F. C. ; Maat, G. J. R.
Fonte: Springer-Verlag Publicador: Springer-Verlag
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
17.96%
Diffuse idiopathic skeletal hyperostosis (DISH) is a common but often unrecognized systemic disorder observed mainly in the elderly. DISH is diagnosed when the anterior longitudinal ligament of the spine is ossified on at least four contiguous spinal levels or when multiple peripheral enthesopathies are present. The etiology of DISH is unknown but previous studies have shown a strong association with obesity and insulin-independent diabetes mellitus. DISH can lead to back pain, dysphagia, myelopathy, musculoskeletal impairment and grossly unstable spine fractures after minor trauma. In archeological studies a high prevalence of DISH has been demonstrated in ancient clergymen. The present study describes the pathological changes of human remains excavated from the abbey court (Pandhof) in the city of Maastricht, The Netherlands. Human remains of 51 individuals buried between 275 and 1795 ce were excavated and examined. The remains were investigated according to a standardized physical anthropological report and individuals demonstrating ossification of spinal ligaments and/or multiple peripheral enthesopathies were included in the study group. The authors reviewed all available material and after reaching consensus, each abnormality found was given a diagnosis and subsequently recorded. After examination...

Nonarticular Rheumatism

Atkinson, Martin H.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /02/1981 EN
Relevância na Pesquisa
16.88%
Nonarticular rheumatism refers to a group of conditions characterized by musculoskeletal aches and pains which do not arise from joints. A number of different entities are considered under this definition. They are classified either as generalized conditions which include polymyalgia rheumatica, fibrositis and aches and pains NYD, or localized conditions which include the enthesopathies: tendonitis, epicondylitis and fasciitis, tenosynovitis and bursitis. The treatment of most of these conditions is expectant, because they tend to be self-limiting and improve despite therapeutic interventions. The exception is polymyalgia rheumatica, which requires low dose steroids for a varying period of time—sometimes years.

Diffuse idiopathic skeletal hyperostosis in the Medici, Grand Dukes of Florence (XVI century)

Giuffra, Valentina; Giusiani, Sara; Fornaciari, Antonio; Villari, Natale; Vitiello, Angelica; Fornaciari, Gino
Fonte: Springer-Verlag Publicador: Springer-Verlag
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
16.88%
Diffuse idiopathic skeletal hyperostosis (DISH) is a common systemic disorder characterised by the ossification of the anterior longitudinal spinal ligament involving at least three contiguous vertebrae and by diffuse extraspinal enthesopathies. The condition is associated with the male sex and with advanced age; its aetiology is uncertain, but seems to be related to obesity and diabetes. The most recent studies in archaeological series demonstrated a relation between high social status and the incidence of DISH. The present study examines two cases of DISH found amongst the members of the Medici family buried in the Basilica of San Lorenzo in Florence. The skeletons of the Grand Dukes Cosimo I (1519–1574) and his son Ferdinand I (1549–1609) showed the typical features of the condition. This result is related to the obesity of the Grand Dukes, attested by the written and artistic sources, and to the protein-based alimentation demonstrated by a paleonutritional study, thus furnishing further evidence to the significance of DISH as a life style.

Long-Term Clinical Outcome and Carrier Phenotype in Autosomal Recessive Hypophosphatemia Caused by a Novel DMP1 Mutation

Mäkitie, Outi; Pereira, Renata C; Kaitila, Ilkka; Turan, Serap; Bastepe, Murat; Laine, Tero; Kröger, Heikki; Cole, William G; Jüppner, Harald
Fonte: Wiley Subscription Services, Inc., A Wiley Company Publicador: Wiley Subscription Services, Inc., A Wiley Company
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
16.88%
Homozygous inactivating mutations in DMP1 (dentin matrix protein 1), the gene encoding a noncollagenous bone matrix protein expressed in osteoblasts and osteocytes, cause autosomal recessive hypophosphatemia (ARHP). Herein we describe a family with ARHP owing to a novel homozygous DMP1 mutation and provide a detailed description of the associated skeletal dysplasia and carrier phenotype. The two adult patients with ARHP, a 78-year-old man and his 66-year-old sister, have suffered from bone pain and lower extremity varus deformities since early childhood. With increasing age, both patients developed severe joint pain, contractures, and complete immobilization of the spine. Radiographs showed short and deformed long bones, significant cranial hyperostosis, enthesopathies, and calcifications of the paraspinal ligaments. Biochemistries were consistent with hypophosphatemia owing to renal phosphate wasting; markers of bone turnover and serum fibroblast growth factor 23 (FGF-23) levels were increased significantly. Nucleotide sequence analysis of DMP1 revealed a novel homozygous mutation at the splice acceptor junction of exon 6 (IVS5-1G > A). Two heterozygous carriers of the mutation also showed mild hypophosphatemia, and bone biopsy in one of these individuals showed focal areas of osteomalacia. In bone...

Heel pain due to psoriatic arthritis in a 50 year old recreational male athlete: case report

Yedon, Dominique Forand; Howitt, Scott
Fonte: Canadian Chiropractic Association Publicador: Canadian Chiropractic Association
Tipo: Artigo de Revista Científica
Publicado em /12/2011 EN
Relevância na Pesquisa
16.88%
Heel pain is a common presentation in a sports injury practice, with a list of common differentials including achilles tendinopathy and retrocalcaneal bursitis. However, seronegative arthritis can also cause enthesopathies that produce heel pain and should be considered in a differential diagnosis list. In this case, a 50 year old recreationally active male presented with non-traumatic insidious heel pain and without history of any skin conditions or any other symptoms of seronegative spondyloarthritis. Clinical suspicion led to laboratory testing and radiographs/bone scan which yielded the diagnosis of psoriatic arthritis.

The tibialis posterior tendon

Lhoste-Trouilloud, A.
Fonte: Elsevier Publicador: Elsevier
Tipo: Artigo de Revista Científica
Publicado em 09/03/2012 EN
Relevância na Pesquisa
16.88%
The tibialis posterior tendon is the largest and anteriormost tendon in the medial ankle. It produces plantar flexion and supination of the ankle and stabilizes the plantar vault. Sonographic assessment of this tendon is done with high-frequency, linear-array transducers; an optimal examination requires transverse retromalleolar, longitudinal retromalleolar, and distal longitudinal scans, as well as dynamic studies. Disorders of the posterior tibial tendon include chronic tendinopathy with progressive rupture, tenosynovitis, acute rupture, dislocation and instability, enthesopathies. The most common lesion is a progressive “chewing gum” lesion that develops in a setting of chronic tendinopathy; it is usually seen in overweight women over 50 years of age with valgus flat feet. Medial ankle pain must also be carefully investigated, and the presence of instability assessed with dynamic maneuvers (forced inversion, or dorsiflexion) of the foot. Sonography plays an important role in the investigation of disorders involving the posterior tibial tendon.

Where tendons and ligaments meet bone: attachment sites (‘entheses’) in relation to exercise and/or mechanical load

Benjamin, M; Toumi, H; Ralphs, J R; Bydder, G; Best, T M; Milz, S
Fonte: Blackwell Science Inc Publicador: Blackwell Science Inc
Tipo: Artigo de Revista Científica
Publicado em /04/2006 EN
Relevância na Pesquisa
18.34%
Entheses (insertion sites, osteotendinous junctions, osteoligamentous junctions) are sites of stress concentration at the region where tendons and ligaments attach to bone. Consequently, they are commonly subject to overuse injuries (enthesopathies) that are well documented in a number of sports. In this review, we focus on the structure–function correlations of entheses on both the hard and the soft tissue sides of the junction. Particular attention is paid to mechanical factors that influence form and function and thus to exploring the relationship between entheses and exercise. The molecular parameters indicative of adaptation to mechanical stress are evaluated, and the basis on which entheses are classified is explained. The application of the ‘enthesis organ’ concept (a collection of tissues adjacent to the enthesis itself, which jointly serve the common function of stress dissipation) to understanding enthesopathies is considered and novel roles of adipose tissue at entheses are reviewed. A distinction is made between different locations of fat at entheses, and possible functions include space-filling and proprioception. The basic anchorage role of entheses is considered in detail and comparisons are explored between entheses and other biological ‘anchorage’ sites. The ability of entheses for self-repair is emphasized and a range of enthesopathies common in sport are reviewed (e.g. tennis elbow...

An important Norwegian contribution to the study of the bursae of the upper and lower extremities

Musil, Vladimir; Selnes, Christoffer V; Falck, Aleksander T; Sandve, Lars; Shekarchi, Siamek; O'Donnell, Bruce; Kachlik, David
Fonte: Informa Healthcare Publicador: Informa Healthcare
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
16.88%
We present a critical analysis of the monograph of A.S.D. Synnestvedt (1869) “En anatomisk beskrivelse af de paa over- og underestremiteterne forekommende Bursae mucosae”. The analysis was completed using anatomical information from the historically oldest publications dealing with the bursae of the extremities: Albinus (1734), Monro (1788), Rosenmüller (1799). We are of the opinion that Synnestvedt's publication is important, not only historically but also as a source of information for recent medical practitioners. Synnestvedt's monograph has a wealth of literary citations, unambiguous opinions of seasoned anatomists regarding the structure and function of the synovial membrane, and detailed descriptions of dissections he performed on fetal and adult cadavers. The information in this publication may enhance the diagnosis of bursopathies and enthesopathies of the extremities.