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Meningoencefalite necrotizante de cão Maltês; Necrotizing meningoencephalitis of Maltese dog

VIOLIN, Kalan Bastos; QUEIROZ, Nicolle Gilda Teixeira de; HOSOMI, Fernando Yutaka Moniwa; RAMOS, Adriano Tony; AMARAL, Helena Arantes do; KOGIKA, Márcia Mery; MACHADO, Gisele Fabrino; MAIORKA, Paulo César
Fonte: Universidade Federal de Santa Maria Publicador: Universidade Federal de Santa Maria
Tipo: Artigo de Revista Científica
POR
Relevância na Pesquisa
36.74%
A Meningoencefalite Necrotizante (MEN) é uma encefalopatia causada por uma disfunção inflamatória de característica necrotizante. O objetivo deste relato é descrever os aspectos clínicos e anatomopatológicos da Meningoencefalite Necrotizante (MEN) em um cão Maltês. A doença tem um caráter necrótico único e está relacionada intimamente à Encefalite do Cão Pug (ECP) devido a suas semelhanças, bem como à Leucoencefalite Necrotizante (LEN). Embora o primeiro relato de caso de ECP tenha mais de 15 anos e o primeiro relato de caso de MEN em Maltês tenha 11 anos, há muito a ser revelado sobre a etiologia e os mecanismos imunopatológicos da doença. Neste trabalho, relata-se o caso de um cão Maltês com sinais que foram compatíveis com a MEN. Foram detectadas nas imagens macroscópicas, cavitação cerebral, e na microscopia, perda de células do parênquima em certas regiões do córtex cerebral. A partir dessas descobertas descreve-se o primeiro caso de MEN em cão Maltês no Brasil.; The Necrotizing Meningoencephalitis (NME) is an encephalopathy caused by an inflammatory dysfunction with necrotic characterization. The aim of this report is to describe the anatomopathological features of the NME in a Maltese dog. The disease has a unique necrotic pattern and is closely related to Pug Dog Encephalitis (PDE) because of their similarity as well as to Necrotizing Leukoencephalitis (NLE). Although the first PDE report has more than 15 years and the first Maltese NME report has 11 years there is a lot to be unveiled about the etiologic and the immunopathologic mechanisms of the disease. Here we report one case of a Maltese dog with signs that were compatible with NME. The gross morphology pictures with the cerebral cavitation and the histological loss of parenchymal cells in some regions of the cerebral cortex were detected. Based on these findings...

Dog culling and replacement in an area endemic for visceral leishmaniasis in Brazil

NUNES, Caris Maroni; LIMA, Valeria Marcal Felix de; PAULA, Henrique Borges de; PERRI, Silvia Helena Venturoli; ANDRADE, Andrea Maria de; DIAS, Francisca Elda Ferreira; BURATTINI, Marcelo Nascimento
Fonte: ELSEVIER SCIENCE BV Publicador: ELSEVIER SCIENCE BV
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
36.84%
Measures employed to control visceral leishmaniasis in Brazil have focused on vector control by residual insecticide spraying and diagnosis of infection with elimination of positive dogs. We describe dog culling and replacement in a Brazilian endemic area (the Alvorada District, Aracatuba, SP) in order to better understand dog population dynamics when elimination of the dog reservoir is adopted as the main control measure. From August 2002 to July 2004, 60.9% of the estimated dog population for the area was culled with a mean age of 34 months old. The presence of anti-Leishmania sp. antibodies was recorded for only 26.7% of the euthanized canines. Replacement was observed in 38.8% of the cases, some of them by 2 or more dogs and in a mean time of 4 months. Dogs were replaced mostly by puppies of both sexes with a mean age of 6.8 months. From August 2002 to April 2005 we were able to follow-up 116 of these dogs, during a mean time of 8.7 months. Canine visceral leishmaniasis seropositivity by ELISA was observed in 42.2% of the followed dogs, 30.6% of which were already positive at the first evaluation. By the end of the follow-up period 37% of the dogs were submitted to euthanasia, with a mean age of 18.3 months. In the studied CVL endemic area of Brazil...

A method for simultaneous detection and identification of Brazilian dog- and vampire bat-related rabies virus by reverse transcription loop-mediated isothermal amplification assay

SAITOU, Yasumasa; KOBAYASHI, Yuki; HIRANO, Shinji; MOCHIZUKI, Nobuyuki; ITOU, Takuya; ITO, Fumio H.; SAKAI, Takeo
Fonte: ELSEVIER SCIENCE BV Publicador: ELSEVIER SCIENCE BV
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
36.74%
At present, the sporadic occurrence of human rabies in Brazil can be attributed primarily to dog- and vampire bat-related rabies viruses. Reverse transcription loop-mediated isothermal amplification (RT-LAMP) was employed as a simultaneous detection method for both rabies field variants within 60 min. Vampire bat-related rabies viruses could be distinguished from dog variants by digesting amplicons of the RT-LAMP reaction using the restriction enzyme Alwl. Amplification and digestion could both be completed within 120 min after RNA extraction. In addition, the RI-LAMP assay also detected rabies virus in isolates from Brazilian frugivorous bats and Ugandan dog, bovine and goat samples. In contrast, there were false negative results from several Brazilian insectivorous bats and all of Chinese dog, pig, and bovine samples using the RI-LAMP assay. This study showed that the RT-LAMP assay is effective for the rapid detection of rabies virus isolates from the primary reservoir in Brazil. Further improvements are necessary so that the RT-LAMP assay can be employed for the universal detection of genetic variants of rabies virus in the field. (C) 2010 Elsevier B.V. All rights reserved.; Kurozumi Medical Foundation; Ministry of Education, Culture...

A dog at the keyboard: using arbitrary signs to communicate requests

ROSSI, Alexandre Pongracz; ADES, Cesar
Fonte: SPRINGER HEIDELBERG Publicador: SPRINGER HEIDELBERG
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
36.74%
As a consequence of domestication, dogs have a special readiness for communication with humans. We here investigate whether a dog might be able to acquire and consistently produce a set of arbitrary signs in her communication with humans, as was demonstrated in ""linguistic"" individuals of several species. A female mongrel dog was submitted to a training schedule in which, after basic command training and after acquiring the verbal labels of rewarding objects or activities, she learned to ask for such objects or activities by selecting lexigrams and pressing keys on a keyboard. Systematic records taken during spontaneous interaction with one of the experimenters showed that lexigrams were used in an appropriate, intentional way, in accordance with the immediate motivational context. The dog only utilized the keyboard in the experimenter`s presence and gazed to him more frequently after key pressing than before, an indication that lexigram use did have communicative content. Results suggest that dogs may be able to learn a conventional system of signs associated to specific objects and activities, functionally analogous to spontaneous soliciting behaviors and point to the potential fruitfulness of the keyboard/lexigram procedure for studying dog communication and cognition. This is the first report to systematically analyze the learning of arbitrary sign production in dogs.

Demographic characterization of supervised dog and cat populations in Sao Paulo city, Brazil

Canatto, B. D.; Silva, E. A.; Bernardi, F.; Mendes, M. C. N. C.; Paranhos, N. T.; Dias, R. A.
Fonte: ARQUIVO BRASILEIRO MEDICINA VETERINARIA ZOOTECNIA; MINAS GERAIS Publicador: ARQUIVO BRASILEIRO MEDICINA VETERINARIA ZOOTECNIA; MINAS GERAIS
Tipo: Artigo de Revista Científica
POR
Relevância na Pesquisa
36.74%
This study aimed to estimate the owned dog and cat populations of Sao Paulo city using a complex sample with random selection in two stages. In each administrative district, six census sectors and 20 households in each sampled sector were visited from September 2006 to September 2009, totalizing 11,272 interviews. The human: dog ratio was 4.34 and the human: cat ratio was 19.33. The dog population was 2,507,401 and the cat population, 562,965. The dog population was composted of 52.7% males, while among the cat population it was 45.1%. The proportion of sterilized females (23.4% among dogs and 46.1% among cats) was higher than males (11.4% among dogs and 31.5% among cats). The mean age of dogs was 4.99 years, and for cats, 3.53 years. The proportion of restricted (without access to the street) dogs, 64.4%, was higher than restricted cats, 42.5%. The average number of animals/household was 1.60 for dogs and 1.69 for cats. The animal ownership is associated with cultural factors, therefore the characterization of canine and feline population is essential to implement an adequate animal population management program and zoonosis control.

Hemoperitoneum in a Dog with Hepatic Splenosis

Pavarini, Saulo Petinatti; Oliveira, Eduardo Conceição de; Santos, Adriana da Silva; Sonne, Luciana; Raymundo, Djeison Lutier; Juffo, Gregory Duarte; Bezerra Junior, Pedro Soares; Driemeier, David
Fonte: Universidade Federal do Rio Grande do Sul Publicador: Universidade Federal do Rio Grande do Sul
Tipo: Artigo de Revista Científica Formato: application/pdf
POR
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36.74%
Background: Ectopic splenic tissue results from the autotransplantation and seeding of splenic tissue, often secondary to splenic trauma or splenectomy. Splenic implantations occur mostly as nodules within the peritoneal cavity and constitute an incidental finding at necropsy, surgery, or imaging investigations. This report addresses a case of hemoperitoneum associated with hepatic splenosis in a dog that became ill several years after splenic trauma. Case: A 9-year-old castrated female Dachshund was presented to the veterinary assistance due to an acute onset of abdominal pain and distension. After recovering from a severe trauma caused by a car accident about five years previously, the dog remained apparently normal. Upon admission the dog also showed anorexia, oliguria (dark yellow urine), increased pulse rate, tachypnea, and hypothermy (37.1ºC). Palpation revealed abdominal distension attributed to large amounts of peritoneal fluid and a large multinodular mass detected in the left side of the abdomen. While white cell and platelet counts were within the normal range, hematocrit (26 to 24%) and erythrocyte counts (3.08 to 2.84 x 106/mL), and hemoglobin content (8.1 to 7.8 g/ dL) decreased as indicated within 36 h after admission. Plasmatic levels of alanine transaminase (ALT-12.1U/L) and creatinine (1.04 mg/dL) were consistent with normal canine patterns. Abdominocentesis revealed a non-clotting and reddish effusion with density of 1.032 and numerous nucleated cells (neutrophils 61%...

Prevalence of dog intestinal parasites and risk perception of zoonotic infection by dog owners in São Paulo State, Brazil

Katagiri, S.; Oliveira-Sequeira, T. C. G.
Fonte: Blackwell Publishing Publicador: Blackwell Publishing
Tipo: Artigo de Revista Científica Formato: 406-413
ENG
Relevância na Pesquisa
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Coprological examination was used to estimate the prevalence of gastrointestinal parasites in stray and domiciled dogs from Botucatu, São Paulo State, Brazil. Risk factors for dog infection were assessed in relation to demographic, husbandry and management data. The dog owners completed a questionnaire survey on some aspects of dog parasitism such as parasite species, mechanisms of infection, awareness of zoonotic diseases and history of anthelmintic usage. Parasites were found in the faeces of 138 dogs, with an overall prevalence of 54.3%. Dogs harbouring one parasite were more common (31.4%) than those harbouring two (18.5%), three (3.2%) or four (1.2%). The following parasites and their respective frequencies were detected: Ancylostoma (37.8%), Giardia (16.9%), Toxocara canis (8.7%), Trichuris vulpis (7.1%), Dipylidium caninum (2.4%), Isospora (3.5%), Cryptosporidium (3.1%) and Sarcocystis (2.7%). Stray dogs were found more likely to be poliparasitized (P < 0.01) and presented higher prevalence of Ancylostoma, T. canis and Giardia (P < 0.01) than domiciled ones. Toxocara canis was detected more frequently in dogs with < 6 months of age (P < 0.05) and no effect of sex or breed could be observed (P > 0.05). Except for Ancylostoma...

Dog culling and replacement in an area endemic for visceral leishmaniasis in Brazil

Nunes, Caris Maroni; Felix de Lima, Valeria Marcal; de Paula, Henrique Borges; Venturoli Perri, Silvia Helena; de Andrade, Andrea Maria; Ferreira Dias, Francisca Elda; Burattini, Marcelo Nascimento
Fonte: Elsevier B.V. Publicador: Elsevier B.V.
Tipo: Artigo de Revista Científica Formato: 19-23
ENG
Relevância na Pesquisa
36.84%
Measures employed to control visceral leishmaniasis in Brazil have focused on vector control by residual insecticide spraying and diagnosis of infection with elimination of positive dogs. We describe dog culling and replacement in a Brazilian endemic area (the Alvorada District, Aracatuba, SP) in order to better understand dog population dynamics when elimination of the dog reservoir is adopted as the main control measure. From August 2002 to July 2004, 60.9% of the estimated dog population for the area was culled with a mean age of 34 months old. The presence of anti-Leishmania sp. antibodies was recorded for only 26.7% of the euthanized canines. Replacement was observed in 38.8% of the cases, some of them by 2 or more dogs and in a mean time of 4 months. Dogs were replaced mostly by puppies of both sexes with a mean age of 6.8 months. From August 2002 to April 2005 we were able to follow-up 116 of these dogs, during a mean time of 8.7 months. Canine visceral leishmaniasis seropositivity by ELISA was observed in 42.2% of the followed dogs, 30.6% of which were already positive at the first evaluation. By the end of the follow-up period 37% of the dogs were submitted to euthanasia, with a mean age of 18.3 months. In the studied CVL endemic area of Brazil...

Occurrence and expression of p53 suppressor gene and c-Myc oncogene in dog eyelid tumors

Lopes, Rodrigo Antonio; Cardoso, Tereza Cristina; Luvizotto, Maria Cecília Rui; de Andrade, Alexandre Lima
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Artigo de Revista Científica Formato: 69-75
ENG
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Purpose: To detect the occurrence and expression of the suppressor gene p53 and of the oncogene c-Myc in eyelid tumors of dogs using the PCR, RT-PCR, PCR-ELISA and RT-PCR-ELISA techniques. These genes have not been described in dog eyelid tumors before. Methods: Nine samples of eyelid or third eyelid epithelial tumors were obtained from the archives of the Department of Veterinary Pathology. Tumor diagnosis was confirmed by evaluation of hematoxylin-eosin stained sections, and immunohistochemistry for cytokeratin AE1/AE3 and vimentin V9. A canine mammary tumor was used for positive control. Agarose gel electrophoresis, PCR-ELISA and RT-PCR-ELISA were used to detect p53 and c-Myc genes. Results: The occurrence of p53 was detected in most of the eyelid tumors and third eyelid tumors studied (88.8%, n = 8) and was expressed in 75% of the positive samples, as indicated by ELISA. The c-Myc gene was found in 77.7% (n = 7) of the samples and was expressed in eight samples. Conclusions: Eyelid and third eyelid tumors of dogs express both the p53 and the c-Myc genes as shown by PCR and RT-PCR. However, PCR ELISA and RT-PCR ELISA were more efficient in assessing occurrence and expression of these genes because they identified amplified products that were not detected by agarose gel electrophoresis. © 2010 American College of Veterinary Ophthalmologists.

Case report: Disseminated Mycobacterium tuberculosis infection in a dog

Martinho, Anna Paula Vitirito; Franco, Marília Masello Junqueira; Ribeiro, Márcio Garcia; Perrotti, Isabella Belletti Mutt; Mangia, Simone Henriques; Megid, Jane; Vulcano, Luiz Carlos; Lara, Gustavo Henrique Batista; Santos, Adolfo Carlos Barreto; Leite
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Artigo de Revista Científica Formato: 596-600
ENG
Relevância na Pesquisa
36.78%
An uncommon disseminated Mycobacterium tuberculosis infection is described in a 12-year-old female dog presenting with fever, dyspnea, cough, weight loss, lymphadenopathy, melena, epistaxis, and emesis. The dog had a history of close contact with its owner, who died of pulmonary tuberculosis. Radiographic examination revealed diffuse radio-opaque images in both lung lobes, diffuse visible masses in abdominal organs, and hilar and mesenteric lymphadenopathy. Bronchial washing samples and feces were negative for acid-fast organisms. Polymerase chain reaction (PCR)-based species identification of bronchial washing samples, feces, and urine revealed M. tuberculosis using PCR-restriction enzyme pattern analysis-PRA. Because of public health concerns, which were worsened by the physical condition of the dog, euthanasia of the animal was recommended. Rough and tough colonies suggestive of M. tuberculosis were observed after microbiological culture of lung, liver, spleen, heart, and lymph node fragments in Löwenstein-Jensen and Stonebrink media. The PRA analysis enabled diagnosis of M. tuberculosis strains isolated from organs. Copyright © 2013 by The American Society of Tropical Medicine and Hygiene.

Neighborhood and postal worker characteristics associated with dog bites in postal workers of the Brazilian National Postal Service in Curitiba

Oliveira,Eduardo Alexandre de; Manosso,Rose Maria; Braune,Gisela; Marcenovicz,Priscila Cavalheiro; Kuritza,Leandro Nagae; Ventura,Henrique Larsen Brunow; Paploski,Igor Adolfo Dexheimer; Kikuti,Mariana; Biondo,Alexander Welker
Fonte: ABRASCO - Associação Brasileira de Saúde Coletiva Publicador: ABRASCO - Associação Brasileira de Saúde Coletiva
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/05/2013 EN
Relevância na Pesquisa
36.74%
Dog bites are the third most common cause of absenteeism among postal workers of the Brazilian National Postal Service in Southern Brazil, with an average off-work time of approximately two days for each biting episode. The objective of this study was to evaluate the neighborhood characteristics involving dog bites that occurred during work time in postal workers, its impact on work and consequent preventive alternatives. A descriptive and analytical cross-sectional study was designed for all Curitiba postal workers. Data were descriptively analyzed and the hypothesis of correlation between median monthly income, population density and occurrence of dog bites was tested. A total of 34.9% of the postal workers answered the questionnaire and 64.6% of them had been bitten while working. The odds of bites occurring in a neighborhood increase by 1.035 times for every increase in one unit in the population density and decrease by 0.998 times for every increase of US$ 1.00 in the neighborhood median monthly income of the head of the family. The occurrence of dog bites among postal workers in Curitiba is related to income and population density and prevention strategies should address mailbox position and adequate fencing to provide protection for postal workers.

Hotspots of mutation and breakage in dog and human chromosomes

Webber, Caleb; Ponting, Chris P.
Fonte: Cold Spring Harbor Laboratory Press Publicador: Cold Spring Harbor Laboratory Press
Tipo: Artigo de Revista Científica
Publicado em /12/2005 EN
Relevância na Pesquisa
36.81%
Sequencing of the dog genome allows an investigation of the location-dependent evolutionary processes that occurred since the common ancestor of primates and carnivores, ∼95 million years ago. We investigated variations in G+C nucleotide fraction and synonymous nucleotide substitution rates (Ks) across dog and human genomes. Our results show that dog genes located either in subtelomeric and pericentromeric regions, or in short synteny blocks, possess significantly elevated G+C fraction and Ks values. Human subtelomeric, but not pericentromeric, genes also exhibit these elevations. We then examined 1.048 Gb of human sequence that is likely not to have been located near a primate telomere at any time since the common ancestor of dog and human. We observed that regions of highest G+C or Ks (“hotspots”; median sizes of 0.5 or 1.3 Mb, respectively) within this sequence were preferentially segregated to dog subtelomeres and pericentromeres during the rearrangements that eventually gave rise to the extant canine karyotype. Our data cannot be accounted for solely on the basis of gradually elevating G+C fractions in subtelomeric regions as a consequence of biased gene conversion. Rather, we propose that high G+C sequences are found preferentially within dog subtelomeres as a direct consequence of chromosomal fission occurring more frequently within regions elevated in G+C.

Immunohistochemical evaluation of intermediate filament nestin in dog hair follicles

Mercati, F.; Pascucci, L.; Gargiulo, A.M.; Dall’Aglio, C.; Ceccarelli, P.
Fonte: Murcia : F. Hernández Publicador: Murcia : F. Hernández
Tipo: Artigo de Revista Científica Formato: application/pdf
ENG
Relevância na Pesquisa
36.74%
Hair follicles (HFs) are self-renewing structures that reconstitute themselves through the hair cycle. They maintain reservoirs of stem cells (SC) that are thought to reside in the bulge area, a region localized in the lowermost permanent portion of HFs. In mice and humans, HF bulge cells express nestin and present stem features as pluripotency. Nestin is a class VI intermediate filament protein; it was first described as a specific marker of CNS stem cells, but recent studies suggest that it may represent a more general stem cell marker (Wiese et al., 2004; Hoffman, 2006). Bulge cell characteristics have mainly been studied in mice and humans, but recently, a bulge-like region was identified also in dog HFs (Pascucci et al., 2006). In this work we investigate the presence and localization of nestin in dog HFs with the aim of evaluating its expression and to correlate it with the location of the bulge-like region. Immunostaining of skin samples collected from healthy dogs was performed by using a rabbit anti-nestin polyclonal antibody. The presence of a population of immunoreactive cells was revealed in the hair follicle middle region, at the arrector pili muscle insertion level. An immunohistochemical signal was detected only in primary hair follicles throughout the hair cycle. These observations led us to conclude that nestin positive cells are located in the bulge-like region of dog HFs and strengthen our hypothesis regarding the correlation between this region and the dog HF stem compartment.

Gastrointestinal parasite risk in dog parks in the Lisbon area

Ferreira, Ana Maria Nogueira
Fonte: Universidade de Lisboa. Faculdade de Medicina Veterinária Publicador: Universidade de Lisboa. Faculdade de Medicina Veterinária
Tipo: Dissertação de Mestrado
Publicado em 28/07/2015 ENG
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Dissertação de Mestrado Integrado em Medicina Veterinária; Dog parks may pose a risk for the transmission of parasitic zoonotic agents via the faeces and soil contact. This is the first study to investigate gastrointestinal infections in park-attending dogs in Lisbon. The research was carried out under the frame of a field study including both parasitological and a survey approach. 369 faecal and 18 soil samples were collected from three dog parks in the Lisbon area and analysed for parasite eggs. 102 questionnaires were filled. The overall prevalence for positive faecal samples was 33%. Ancylostomatidae represent 17%, Cryptosporidium spp. 12%, Giardia spp. 11%, Toxascaris leonina and Cystoisospora spp. 1% each, Toxocara spp. 0.5% and Sarcocystis spp. 0.3%. From soil samples, 28% were contaminated with only Ancylostomatidae eggs. In the last 12 months 94% of the dogs were observed by a veterinarian. 90% were dewormed in the previous six months, from which 28% at least four times a year. Additionally, 26% of the dogs share the house with at least one dog, 50% visit the park daily, and 75% were always allowed to be off-leash. Also, 1% was fed with raw meat. Despite 94% of the owner’s claimed faecal collection of their pets, it was common to see 10-20 faecal samples on the environment of every dog space on sampling days. Regarding the pet-owner relationship...

Neutron activation analysis for assessing chemical composition of dry dog foods

Elias, Camila; Fernandes, Elisabete Aparecida De Nadai; Bacchi, Marcio Arruda
Fonte: SPRINGER; DORDRECHT Publicador: SPRINGER; DORDRECHT
Tipo: Artigo de Revista Científica
ENG
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Brazil holds the second largest population of domestic dogs in the world, with 33 million dogs, only behind the United States. The annual consumption of dog food in the country is 1.75 million tons, corresponding to the World's sixth in trade turnover. Dog food is supposed to be a complete and balanced diet, formulated with high quality ingredients. All nutrients and minerals required for an adequate nutrition of dogs are added to the formulation to ensure longevity and welfare. In this context, the present study aimed at assessing the chemical composition of dry dog foods commercialized in Brazil. Thirty-four samples were acquired in the local market of Piracicaba and analyzed by instrumental neutron activation analysis (INAA) to determine the elements As, Br, Ca, Co, Cr, Cs, Fe, K, La, Na, Rb, Sb, Sc, Se, U, and Zn. In general, the concentrations of Ca, Fe, K, Na, and Zn complied with the values required by the Association of American Feed Control Officials (AAFCO). To evaluate the safety of dog food commercialized in Brazil, further investigation is necessary to better understand the presence of toxic elements found in this study, i.e. Sb and U. INAA was useful for the screening analysis of different types and brands of dry dog foods for the determination of both essential and toxic elements.; State of Sao Paulo Research Foundation (FAPESP); State of Sao Paulo Research Foundation-FAPESP [10/52425-7]

Prótese total articulada de joelho utilizada no tratamento de osteossarcoma apendicular em cão; Total articulated prosthesis for treatment of apendicular osteosarcoma in a dog

FERRIGNO, Cássio Ricardo Auada; CAMPOS, Andressa Gianotti; STOPIGLIA, Ângelo João; FANTONI, Denise Tabacchi
Fonte: Universidade Federal de Santa Maria Publicador: Universidade Federal de Santa Maria
Tipo: Artigo de Revista Científica
POR
Relevância na Pesquisa
36.78%
O objetivo do trabalho foi reportar o planejamento cirúrgico, a técnica operatória, a instrumentação e os resultados da substituição completa do terço médio distal do fêmur, do platô tibial e da articulação do joelho por prótese em um cão acometido por osteossarcoma no fêmur esquerdo. A prótese foi confeccionada em aço, apresentando três componentes articulados, mantendo o movimento semelhante à articulação do joelho. As porções femorais e tibiais da prótese foram cimentadas aos respectivos ossos, após ostectomia do fêmur e do platô tibial. O animal foi submetido a seis sessões de quimioterapia, com doxorrubicina e carboplatina, intercaladas mensalmente, objetivando inibir o crescimento de possíveis metástases pulmonares. Durante os seis primeiros dias, o animal apresentou neuropraxia e impotência funcional do membro. Aos 10 dias, o cão iniciou leve apoio e aos 30 dias já utilizava o membro pélvico de forma mais efetiva, porém, o ângulo de extensão da articulação foi reduzido de 150° a 100° devido à contratura muscular e à fibrose na região da fossa poplítea. Após um ano de observação, não houve melhora do ângulo de extensão do joelho, porém, o animal fazia uso do membro com claudicação. Aos 425 dias de pós-operatório...

The presence of a high-Km hexokinase activity in dog, but not in boar, sperm.

Fernández Novell, Josep M.; Ballester, Joan; Medrano, Antonio; Otaegui Goya, Pedro José; Rigau i Mas, Teresa; Guinovart, Joan J.; Rodríguez Gil, Joan Enric
Fonte: Universidade Autônoma de Barcelona Publicador: Universidade Autônoma de Barcelona
Tipo: Artigo de Revista Científica Formato: application/pdf
Publicado em //2004 ENG
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36.84%
The presence of a high-Km hexokinase activity was tested in both dog and boar spermatozoa. Hexokinase kinetics from dog extracts showed the presence of a specific activity (dog-sperm glucokinase-like protein, DSGLP), in the range of glucose concentrations of 4–10 mM, whereas boar sperm did not show any DSGLP activity. Furthermore, dog-sperm cells, but not those of boar, showed the presence of a protein which specifically reacted against a rat-liver anti-glucokinase antibody. This protein also had a molecular weight equal to that observed in rat-liver extracts, suggesting a close similarity between both the proteins. This glucokinase-like protein was distributed in the peri- and post-acrosomal zones of the head, and the midpiece and principal piece of tail of dog spermatozoa. These results indicate that dog spermatozoa have functional high-Km hexokinase activity, which could contribute to a very fine regulation of their hexose metabolism. This strict regulation could ultimately be very important in optimizing dog-sperm function along its life-time.

Digital dog shelter application

Bzdick, Taryn
Fonte: Rochester Instituto de Tecnologia Publicador: Rochester Instituto de Tecnologia
Tipo: Tese de Doutorado
EN_US
Relevância na Pesquisa
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Pet overpopulation has been a major issue for a long time. Hundreds of thousands of dogs are in shelters all over the country who desperately need homes. When looking up these dogs on shelter web sites it is common to find a small blurb and a low quality photograph in a poorly designed environment about a dog in need of a home. Most of the time these postings are not informative enough to help the potential owner make an educated decision in choosing the right dog for them. Dogs in these shelters would have significantly higher chances of being adopted if they had a stronger web presence than what they currently have. The purpose of this project is to find a way to make dogs up for adoption more appealing, interactive and geared toward a more accurate fit for the potential owner by means of developing a digital shelter dog adoption center. This method would be best used for dogs that have a more difficult time finding a home, such as older dogs, dogs of a specific breed and size, physically or mentally handicapped dogs, or dogs with other special needs.

A review of facial injuries due to dog bites

Abuabara,Allan
Fonte: Medicina Oral, Patología Oral y Cirugía Bucal (Internet) Publicador: Medicina Oral, Patología Oral y Cirugía Bucal (Internet)
Tipo: info:eu-repo/semantics/article; journal article; info:eu-repo/semantics/publishedVersion Formato: text/html; application/pdf
Publicado em 01/07/2006 ENG
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Bite injuries to the head and neck region can result in facial disfigurement with distressing physical and psychological consequences. This article reviewed the causes and management of facial bite wounds due to dog bites. A PUBMED search of the National Library of Medicine from 1995 to December 2005 was conducted. Keywords used in the search were ‘facial wound’, ‘bite wound’, ‘dog bite’. The results showed that the risk factors for dog attacks include: school-aged children, male, households with dogs, male dogs and certain breeds (german shepherds, bull terriers, blue/red heelers, dobermans and rottwellers). Early management of such complex injuries usually guarantees satisfactory outcome. Most of the cases involve a known dog (friends, neighbors) and family pet. Although animal bites are not the most accounted children injuries, deaths may a result of these attacks. Antibiotic therapy is indicated for infected bite wounds and fresh wounds considered at risk for infection, such as extremely large wounds, large hematoma, and cat bites, that appear be more infected than dog bites. Tetanus immunization status and the risk of rabies infection should be routinely addressed in bite wound management. Prevention strategies should be considered for preventing dog bites.

Patterns of occurrence and abundance in colony complexes of the mexican prairie dog (Cynomys mexicanus) in productive and unproductive grasslands

Yeaton,Richard I.; Flores-Flores,José L.
Fonte: Instituto de Ecología A.C. Publicador: Instituto de Ecología A.C.
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2006 EN
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The Mexican prairie dog lives in a small (500-600 km²) area of northeastern Mexico. The species is listed as endangered due to habitat fragmentation from recent large-scale agricultural development in the northern part of its limited geographical range and from shrub encroachment in the south. In this work we aim to study the role of Mexican prairie dog in the ecology of grasslands in the southern Chihuahuan Desert. Most of the species' colonies, particularly in the far south of its range, occur today in short grasslands that grow on low productivity, gypsum-derived soils where the rate of such shrub encroachment is reduced. A survey of the region surrounding these southern colonies indicated that this has not always been the case as evidence of the species' occurrence on more productive alluvial soils in the past is apparent. Biomass production and seasonal prairie dog densities were measured on these low productivity soils in the south of its range and on richer and deeper alluvial soils to the north. Total biomass production was seven times greater and densities were three-and-one-half times greater on the deeper alluvial soils. Adult seasonal densities were not significantly different within a soil type during the period monitored while juvenile densities increased significantly in the summer censuses due to the birth of young. The similar seasonal densities at each site suggest that the Mexican prairie dog is resource limited. An inferential study of the development of one isolated colony on the more productive alluvial soils in the north of the species' range showed lower prairie dog densities in the center of the colony and at the edge of the colony in the zone of recent expansion than in the area peripheral to the center. Vegetation coverage was too scarce in the center of the colony to quantify. The areas peripheral to the center and in the zone of expansion were reduced in coverage of grasses and sedges in comparison to the unutilized surrounding grassland while the palatable grass...