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Profile of three Brazilian birth cohort studies in Ribeirão Preto, SP and São Luís, MA

Cardoso, Viviane C.; Simões, V.M.F.; Barbieri, Marco Antonio; Silva, Alessandra Analu Moreira da; Bettiol, Heloisa; Alves, M.T.S.S.B.; Goldani, Marcelo Zubaran
Fonte: Universidade Federal do Rio Grande do Sul Publicador: Universidade Federal do Rio Grande do Sul
Tipo: Artigo de Revista Científica Formato: application/pdf
POR
Relevância na Pesquisa
56.02%
We describe three birth cohort studies, respectively carried out in 1978/79 and 1994 in Ribeirão Preto, a city located in the most developed region of Brazil, and in 1997/98 in São Luís, a city located in a less developed region. The objective of the present report was to describe the methods used in these three studies, presenting their history, methodological design, objectives, developments, and difficulties faced along 28 years of research. The first Ribeirão Preto study, initially perinatal, later encompassed questions regarding the repercussions of intrauterine development on future growth and chronic adult diseases. The subjects were evaluated at birth (N = 6827), at school age (N = 2861), at the time of recruitment for military service (N = 2048), and at 23/25 years of age (N = 2063). The study of the second cohort, which started in 1994 (N = 2846), permitted comparison of aspects of perinatal health between the two groups in the same region, such as birth weight, mortality and health care use. In 1997/98, a new birth cohort study was started in São Luís (N = 2443), capital of the State of Maranhão. The 1994 Ribeirão Preto cohort and the São Luís cohort are in the second phase of joint follow-up. These studies permit comparative temporal analyses in the same place (Ribeirão Preto 1978/79 and 1994) and comparisons of two contrasting populations regarding cultural...

Profile of three Brazilian birth cohort studies in Ribeirão Preto, SP and São Luís, MA

Cardoso,V.C.; Simões,V.M.F.; Barbieri,M.A.; Silva,A.A.M.; Bettiol,H.; Alves,M.T.S.S.B.; Goldani,M.Z.
Fonte: Associação Brasileira de Divulgação Científica Publicador: Associação Brasileira de Divulgação Científica
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/09/2007 EN
Relevância na Pesquisa
56.02%
We describe three birth cohort studies, respectively carried out in 1978/79 and 1994 in Ribeirão Preto, a city located in the most developed region of Brazil, and in 1997/98 in São Luís, a city located in a less developed region. The objective of the present report was to describe the methods used in these three studies, presenting their history, methodological design, objectives, developments, and difficulties faced along 28 years of research. The first Ribeirão Preto study, initially perinatal, later encompassed questions regarding the repercussions of intrauterine development on future growth and chronic adult diseases. The subjects were evaluated at birth (N = 6827), at school age (N = 2861), at the time of recruitment for military service (N = 2048), and at 23/25 years of age (N = 2063). The study of the second cohort, which started in 1994 (N = 2846), permitted comparison of aspects of perinatal health between the two groups in the same region, such as birth weight, mortality and health care use. In 1997/98, a new birth cohort study was started in São Luís (N = 2443), capital of the State of Maranhão. The 1994 Ribeirão Preto cohort and the São Luís cohort are in the second phase of joint follow-up. These studies permit comparative temporal analyses in the same place (Ribeirão Preto 1978/79 and 1994) and comparisons of two contrasting populations regarding cultural...

Examining life-course influences on chronic disease: the Ribeirão Preto and São Luís birth cohort studies (Brazil)

Batty,G.D
Fonte: Associação Brasileira de Divulgação Científica Publicador: Associação Brasileira de Divulgação Científica
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/09/2007 EN
Relevância na Pesquisa
55.98%
More than any other low- and middle-income country, Brazil has the longest research tradition of establishing, maintaining and exploiting birth cohort studies. This research pedigree is highlighted in the present issue of the Brazilian Journal of Medical and Biological Research, which contains a series of twelve papers from the Ribeirão Preto and São Luis birth cohort studies from the Southeast and Northeast of Brazil, respectively. The topics covered in this raft of reports vary and include predictors of perinatal health and maternal risk factors, early life determinants of cardiovascular risk factors in childhood and adolescence, use of health services, and a description of dietary characteristics of young adults, amongst other topics. There is also a guide to the background, objectives, sampling and protocols employed across these studies, which, together with similar pieces published in past issues of the Brazilian Journal, serve as a very useful starting point, particularly for potential collaborators. In the fervent hope that further follow-up of these cohorts will take place - we provide our own justification for cohort maintenance and extension in this issue - future data collection could include: genetic material, atherosclerosis...

The Pelotas birth cohort study, Rio Grande do Sul, Brazil, 1982-2001

Victora,Cesar G.; Barros,Fernando C.; Lima,Rosângela C.; Behague,Dominique P.; Gonçalves,Helen; Horta,Bernardo L.; Gigante,Denise P.; Vaughan,J. Patrick
Fonte: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz Publicador: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/10/2003 EN
Relevância na Pesquisa
56.04%
Given the growing recognition of the importance of the life course approach for the determination of chronic diseases, birth cohort studies are becoming increasingly important. This paper describes the methods used in the 1982 Pelotas (Brazil) birth cohort study, one of the largest and longest studies of this type in developing countries. All 5,914 hospital births occurring in Pelotas in 1982 (over 99% of all deliveries) were studied prospectively. The main stages of the study took place in 1983, 1984, 1986, 1995, 1997, 2000, and 2001. More than two thousand variables are available for each subject who participated in all stages of the study. Recent phases of the study included the examination of 2,250 males when presenting for the army recruitment exam in 2000, the study of a 27% sample of men and women in 2001 through household visits, and the study of over 400 children born to the cohort women. Follow-up rates in the recent stages of the cohort were 78.9% for the army examination and 69.0% for the household visits. Ethnographic and oral health studies were conducted in sub-samples. Some recent results on blood pressure, adolescent pregnancy, and asthma are presented as examples of utilization of the data. Suggestions on lessons learned for other cohort studies are proposed.

Challenges in comparing the methods and findings of cohort studies of oral health: the Dunedin (New Zealand) and Pelotas (Brazil) studies

De Anselmo Peres, M.; Thomson, W.; Glazer De Anselmo Peres, K.; Horta, B.; Broadbent, J.; Poulton, R.
Fonte: Public Health Assoc Australia Inc Publicador: Public Health Assoc Australia Inc
Tipo: Artigo de Revista Científica
Publicado em //2011 EN
Relevância na Pesquisa
66.06%
OBJECTIVE: to systematically compare methods and some findings from two prospective cohort studies of oral health. METHODS: This paper describes and compares two such population-based birth cohort studies of younger adults: the Dunedin Multidisciplinary Health and Development Study (conducted in New Zealand); and the 1982 Pelotas Birth Cohort Study (conducted in Brazil). RESULTS: The two cohorts showed sociodemographic similarities and differences, with their gender mixes being similar, but their ethnic compositions differing markedly. There were some important similarities and differences in methods. Overall dental caries experience was higher among the Dunedin cohort. Each of the studies has examined the association between childhood-adulthood changes in socio-economic status and oral health in the mid-20s. Both studies observed the greatest disease experience among those who were of low SES in both childhood and adulthood, and the least among those who were of high SES in both childhood and adulthood. In each cohort, disease experience in the upwardly mobile and downwardly mobile groups lay between those two extremes. CONCLUSIONS AND IMPLICATIONS: There are important similarities and differences in both methods and findings. While the need for a degree of methodological convergence in future is noted...

Accuracy of single progesterone test to predict early pregnancy outcome in women with pain or bleeding: Meta-analysis of cohort studies

Verhaegen, J.; Gallos, I.; van Mello, N.; Abdel-Aziz, M.; Takwoingi, Y.; Harb, H.; Deeks, J.; Mol, B.; Coomarasamy, A.
Fonte: BMJ Publishing Group Publicador: BMJ Publishing Group
Tipo: Artigo de Revista Científica
Publicado em //2012 EN
Relevância na Pesquisa
66.01%
Objective To determine the accuracy with which a single progesterone measurement in early pregnancy discriminates between viable and non-viable pregnancy. Design Systematic review and meta-analysis of diagnostic accuracy studies. Data sources Medline, Embase, CINAHL, Web of Science, ProQuest, Conference Proceedings Citation Index, and the Cochrane Library from inception until April 2012, plus reference lists of relevant studies. Study selection Studies were selected on the basis of participants (women with spontaneous pregnancy of less than 14 weeks of gestation); test (single serum progesterone measurement); outcome (viable intrauterine pregnancy, miscarriage, or ectopic pregnancy) diagnosed on the basis of combinations of pregnancy test, ultrasound scan, laparoscopy, and histological examination; design (cohort studies of test accuracy); and sufficient data being reported. Results 26 cohort studies, including 9436 pregnant women, were included, consisting of 7 studies in women with symptoms and inconclusive ultrasound assessment and 19 studies in women with symptoms alone. Among women with symptoms and inconclusive ultrasound assessments, the progesterone test (5 studies with 1998 participants and cut-off values from 3.2 to 6 ng/mL) predicted a non-viable pregnancy with pooled sensitivity of 74.6% (95% confidence interval 50.6% to 89.4%)...

Kriminologische Verlaufs- und Kohortenforschungen - Eine Bibliographie; Birth Cohort and other Longitudinal Studies of Criminal Careers and Desistance in Criminology: A Comprehensive Bibliography

Kerner, Hans-Jürgen; Weitekamp, Elmar G. M.
Fonte: Universität Tübingen Publicador: Universität Tübingen
Tipo: Buch (Monographie)
DE_DE
Relevância na Pesquisa
55.94%
Diese Bibliographie ist aus einem Projekt über vergleichende kriminologische Verlaufuntersuchungen, insbesondere sog. Kohortenstudien entstanden. Sie ist der Orientierung nach genuin international ausgerichtet, versucht also Veröffentlichungen über empirische Studien sowie sonstige Texte zur Materie aus der ganzen Welt zu erfassen. Da ein Großteil des Forschungen in den USA, in England und in den Skandinavischen Staaten durchgeführt wurde und auf Englisch dokumentiert ist, aber auch aus Gründen unserer begrenzten linguistischen Ressourcen, dominieren freilich im Ergebnis englischsprachige Veröffentlichungen zur Materie; deutschsprachige Veröffentlichungen wurden möglichst vollständig zu erfassen versucht; sonstige fremdsprachige Publikationen unterliegen einer deutlich stärker selektiven Auswahl. Die jüngere kriminologische Diskussion über den Ausstieg aus einer kriminellen Karriere ist mit berücksichtigt, jedoch nicht mit dem Anspruch auf Vollständigkeit, da in dem jüngsten Werk von John Laub und Robert Sampson (2003) der Forschungsstand gut aufgearbeitet ist.; The nucleus of this bibliography was created as part of a comparative criminological research project on longitudinal studies of delinquency and crime, particularly on birth cohort studies. We updated and augmented the content considerably over the years until the end of the year 2003. The bibliography is basically international in its scope and orientation. Most of the studies on the subject matter...

Contribution of cohort studies in the analysis of oral health in children and adolescents in Sobral, Ceará

Noro,Luiz Roberto Augusto; Roncalli,Angelo Giuseppe; Teixeira,Ana Karine Macedo
Fonte: Associação Brasileira de Saúde Coletiva Publicador: Associação Brasileira de Saúde Coletiva
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/09/2015 EN
Relevância na Pesquisa
55.95%
The main objective of this study was to identify the oral health status of the child population in a northeastern Brazilian municipality as a strategy to carry out subsequent longitudinal studies to investigate the main determinants of oral diseases in the specific age groups of teenagers and young adults. Epidemiological investigations and interviews were conducted in households by research teams. In the first study, a DMFT (decayed, missing, and filled teeth) score of 1.66 was found for 9-year-olds; although only 23% children aged between 5 and 6 years were caries-free, 32.7% had gingival bleeding and 9.5% were diagnosed with severe malocclusion problems. The second wave of the cohort indicated that the incidence of caries increased progressively according to age, from 1.60 in 12-year-old adolescents to 2.28 in those aged 15. Toothache in the past 6 months, maternal income and school meals, adjusted for the perception of need for treatment, maternal education, and dental visit at least once were the variables associated with high incidence of dental caries. Data collection for the third wave of the cohort is currently underway. Socioeconomic factors and access to health services were associated with the incidence of caries.

COSMIC (Cohort Studies of Memory in an International Consortium): An international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethnic and sociocultural groups

Sachdev, Perminder S; Lionicki, Darren M; Kochan, Nicole A; Crawford, John D; Rockwood, Kenneth; Xiao, Shifu; Li, Juan; Li, Xia; Brayne, Carol; Matthews, Fiona E; Stephan, Blossom C M; Lipton, Richard B; Katz, Mindy J; Ritchie, Karen; Carrière, Isabelle;
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Artigo de Revista Científica Formato: 8 pages
Relevância na Pesquisa
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BACKGROUND: A large number of longitudinal studies of population-based ageing cohorts are in progress internationally, but the insights from these studies into the risk and protective factors for cognitive ageing and conditions like mild cognitive impairment and dementia have been inconsistent. Some of the problems confounding this research can be reduced by harmonising and pooling data across studies. COSMIC (Cohort Studies of Memory in an International Consortium) aims to harmonise data from international cohort studies of cognitive ageing, in order to better understand the determinants of cognitive ageing and neurocognitive disorders. METHODS/DESIGN: Longitudinal studies of cognitive ageing and dementia with at least 500 individuals aged 60 years or over are eligible and invited to be members of COSMIC. There are currently 17 member studies, from regions that include Asia, Australia, Europe, and North America. A Research Steering Committee has been established, two meetings of study leaders held, and a website developed. The initial attempts at harmonising key variables like neuropsychological test scores are in progress. DISCUSSION: The challenges of international consortia like COSMIC include efficient communication among members...

COSMIC (Cohort Studies of Memory in an International Consortium): An international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethnic and sociocultural groups

Anstey, Kaarin J.; Sachdev, Perminder S.; Lipnicki, Darren M.; Kochan, Nicole A.; Crawford, John D.; Rockwood, Kenneth
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Artigo de Revista Científica Formato: 8 pages
Relevância na Pesquisa
66%
Background: A large number of longitudinal studies of population-based ageing cohorts are in progress internationally, but the insights from these studies into the risk and protective factors for cognitive ageing and conditions like mild cognitive impairment and dementia have been inconsistent. Some of the problems confounding this research can be reduced by harmonising and pooling data across studies. COSMIC (Cohort Studies of Memory in an International Consortium) aims to harmonise data from international cohort studies of cognitive ageing, in order to better understand the determinants of cognitive ageing and neurocognitive disorders. Methods/Design: Longitudinal studies of cognitive ageing and dementia with at least 500 individuals aged 60 years or over are eligible and invited to be members of COSMIC. There are currently 17 member studies, from regions that include Asia, Australia, Europe, and North America. A Research Steering Committee has been established, two meetings of study leaders held, and a website developed. The initial attempts at harmonising key variables like neuropsychological test scores are in progress. Discussion: The challenges of international consortia like COSMIC include efficient communication among members...

Methodological aspects of the 1993 Pelotas (Brazil) birth cohort study

Victora,Cesar Gomes; Araújo,Cora Luiza Pavin; Menezes,Ana Maria Batista; Hallal,Pedro Curi; Vieira,Maria de Fátima; Neutzling,Marilda Borges; Gonçalves,Helen; Valle,Neiva Cristina; Lima,Rosangela Costa; Anselmi,Luciana; Behague,Dominique; Gigante,Denis
Fonte: Faculdade de Saúde Pública da Universidade de São Paulo Publicador: Faculdade de Saúde Pública da Universidade de São Paulo
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/02/2006 EN
Relevância na Pesquisa
56.02%
This paper describes the main methodological aspects of a cohort study, with emphasis on its recent phases, which may be relevant to investigators planning to carry out similar studies. In 1993, a population based study was launched in Pelotas, Southern Brazil. All 5,249 newborns delivered in the city's hospitals were enrolled, and sub-samples were visited at the ages of one, three and six months and of one and four years. In 2004-5 it was possible to trace 87.5% of the cohort at the age of 10-12 years. Sub-studies are addressing issues related to oral health, psychological development and mental health, body composition, and ethnography. Birth cohort studies are essential for investigating the early determinants of adult disease and nutritional status, yet few such studies are available from low and middle-income countries where these determinants may differ from those documented in more developed settings.

Restless Legs Syndrome and All-Cause Mortality in Four Prospective Cohort Studies

Szentkirályi, András; Winter, Anke C; Schürks, Markus; Völzke, Henry; Hoffmann, Wolfgang; Buring, Julie Elizabeth; Gaziano, John Michael; Kurth, Tobias; Berger, Klaus
Fonte: BMJ Group Publicador: BMJ Group
Tipo: Artigo de Revista Científica
EN_US
Relevância na Pesquisa
55.95%
Objectives: To evaluate the association between restless legs syndrome (RLS) and all-cause mortality. Design: Four prospective cohort studies. Setting: The Dortmund Health Study (DHS) and the Study of Health in Pomerania (SHIP) from Germany. The Women's Health Study (WHS) and the Physicians’ Health Study (PHS) from the USA. Participants: In DHS: a random sample (n=1 299) from the population of Dortmund; in SHIP: a sample (n=4 291) from residents living in West Pomerania were drawn by multistage random sampling design; in WHS: female healthcare professionals (n=31 370); in PHS: male physicians (n=22 926) Main outcome measures: All-cause mortality. Results: The prevalence of RLS ranged between 7.4% and 11.9% at baseline. During follow-up (ranging between 6 and 11 years) RLS was not associated with increased risk of all-cause mortality in any of the four cohorts. The multivariable-adjusted HRs (95% CI) for all-cause mortality ranged from 0.21 (0.03 to 1.53) to 1.07 (0.93 to 1.23) across the four studies. The HRs for all-cause mortality did not differ according to gender. Conclusions: In these four independently conducted large prospective cohort studies from Germany and the USA, RLS did not increase the risk of all-cause mortality. These findings do not support the hypothesis that RLS is a risk factor for mortality of any cause.

Methods used in the 1982, 1993, and 2004 birth cohort studies from Pelotas, Rio Grande do Sul State, Brazil, and a description of the socioeconomic conditions of participants' families

Barros,Aluísio J. D.; Santos,Iná S.; Matijasevich,Alicia; Araújo,Cora L.; Gigante,Denise P.; Menezes,Ana M. B.; Horta,Bernardo L.; Tomasi,Elaine; Victora,Cesar G.; Barros,Fernando C.
Fonte: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz Publicador: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2008 EN
Relevância na Pesquisa
65.88%
Three birth cohorts are currently being followed in Pelotas, Southern Brazil, in order to assess changes in birth conditions, growth, development, morbidity, and infant mortality, as well as the influence of pre- and perinatal factors on the subsequent morbidity of participants in their adult lives. We provide a description of the methodology used for the cohort studies that began in 1982, 1993, and 2004 in Pelotas, and a description of the economic conditions of the families involved. For the three cohorts, similar strategies were used to recruit babies born to mothers living in the municipality's urban area. These included daily visits to maternity hospitals where births were identified, mothers interviewed, and newborns examined. Over this time frame, there has been a significant reduction in the number of births due to declining fertility rates amongst the target population. Salaries (measured as a multiple of the minimum wage) were stable across cohorts, but quality of life indicators - such as the availability of piped water, flushing toilets and refrigerators - showed clear improvements. Mothers' levels of education improved markedly. Important changes in the demographic profile of risk factors and health outcomes are being recorded by the Pelotas cohorts.

The value of comparing health outcomes in cohort studies: An example of self-rated health in seven studies including 79 653 participants

Anstey, Kaarin; Butterworth, Peter; Windsor, Timothy; Burns, Richard; Sargent-Cox, Kerry; Von Sanden, Chwee Chwee; Christensen, Helen; Booth, Heather; Simons, Leon; Byles, Julie; Gibson, Richard; Luszcz, Mary A; Shaw, Jonathan E; Broe, Gerald; Browning, C
Fonte: Blackwell Publishing Ltd Publicador: Blackwell Publishing Ltd
Tipo: Artigo de Revista Científica
Relevância na Pesquisa
65.97%
Objective: To demonstrate the value of comparing data from multiple cohort studies using the example of self-rated health (SRH). Methods: Seven Australian cohort studies including comparable data on SRH were identified. Comparisons of the distributions of

Q-Coh : a tool to screen the methodological quality of cohort studies in systematic reviews and meta-analyses

Jarde, Alexander; Losilla Vidal, Josep Maria; Vives Brosa, Jaume; Rodrigo Giménez, María F.
Fonte: Universidade Autônoma de Barcelona Publicador: Universidade Autônoma de Barcelona
Tipo: Artigo de Revista Científica Formato: application/pdf
Publicado em //2013 ENG
Relevância na Pesquisa
66.01%
The evaluation of the methodological quality of primary studies in a systematic review is a key process to enhance the likelihood of achieving valid results. When considering non-randomized designs as cohort studies, this process becomes even more critical, since these designs are more susceptible to bias than randomized controlled trials are. Taking this into account, a tool, named Q-Coh, was designed with the aim to screen the methodological quality of the primary studies with a cohort design priming specificity over sensitivity in a reasonable application time. After applying it to 21 prospective cohort studies by three raters, all domains had a moderate to good agreement, with all except one of them having statistically significant kappa values. Despite there is no gold standard for the methodological quality, arguments supporting its validity are given. Future research should assess the psychometric properties of Q-Coh in the context of real meta-analyses, evaluate the influence of the raters’ substantive and methodological expertise on these properties, and explore different ways of including the domains-based ratings of the quality provided by Q-Coh into meta-analyses; La valoración de la calidad metodológica de estudios primarios en una revisión sistemática es un proceso clave para mejorar la validez de los resultados. Al considerar diseños no aleatorizados como los estudios de cohortes...

Aspectos metodológicos da coorte de nascimentos de 1993 em Pelotas, RS; Methodological aspects of the 1993 Pelotas (Brazil) birth cohort study

Victora, Cesar Gomes; Araújo, Cora Luiza Pavin; Menezes, Ana Maria Batista; Hallal, Pedro Curi; Vieira, Maria de Fátima; Neutzling, Marilda Borges; Gonçalves, Helen; Valle, Neiva Cristina; Lima, Rosangela Costa; Anselmi, Luciana; Behague, Dominique; Gi
Fonte: Universidade de São Paulo. Faculdade de Saúde Pública Publicador: Universidade de São Paulo. Faculdade de Saúde Pública
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; ; Formato: application/pdf
Publicado em 01/02/2006 ENG
Relevância na Pesquisa
56.02%
Descrever aspectos metodológicos do estudo da coorte de crianças que podem ser relevantes para pesquisadores que estejam planejando investigações semelhantes. Em 1993, uma coorte de base populacional foi recrutada em Pelotas, RS. Os 5.249 recém-nascidos nos hospitais da cidade foram acompanhados com um, três e seis meses, e com um e quatro anos de idade. Subestudos estão sendo realizados sobre saúde bucal, desenvolvimento psicológico e saúde mental, composição corporal e aspectos etnográficos. Em 2004-5 foi possível entrevistar 87,5% da coorte inicial, com a idade de 10-12 anos. Estudos de coortes de nascimentos são essenciais para investigar os determinantes precoces da morbidade e estado nutricional de adultos. No entanto, há poucos estudos com esta metodologia em países de renda média e baixa, e alguns dos determinantes da situação de saúde podem ser distintos daqueles observados em países ricos.; This paper describes the main methodological aspects of a cohort study, with emphasis on its recent phases, which may be relevant to investigators planning to carry out similar studies. In 1993, a population based study was launched in Pelotas, Southern Brazil. All 5,249 newborns delivered in the city's hospitals were enrolled...

Metodologia do estudo da coorte de nascimentos de 1982 a 2004-5, Pelotas, RS; Metodologia de estudio de la cohorte de nacimientos de 1982 a 2004-5, Pelotas, Sur de Brasil; Methodology of the Pelotas birth cohort study from 1982 to 2004-5, Southern Brazil

Barros, Fernando C; Victora, Cesar G; Horta, Bernardo L; Gigante, Denise P
Fonte: Universidade de São Paulo. Faculdade de Saúde Pública Publicador: Universidade de São Paulo. Faculdade de Saúde Pública
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; ; Formato: application/pdf; application/pdf
Publicado em 01/12/2008 POR; ENG
Relevância na Pesquisa
56.04%
OBJETIVO: Descrever os métodos utilizados no estudo longitudinal e acompanhamento das crianças nascidas em Pelotas (RS) em 1982. MÉTODOS: A coorte foi iniciada com um inquérito de saúde perinatal de todas as 6.011 crianças nascidas nas maternidades de Pelotas em 1982. As 5.914 crianças nascidas vivas foram incluídas nos estudos de acompanhamento. Até 2004-5 foram realizados oito acompanhamentos, com a aplicação de questionários às mães e/ou aos membros da coorte, conforme a faixa etária. Exames antropométricos e clínicos foram realizados nas visitas. Os participantes da coorte são descritos conforme variáveis demográficas, socioeconômicas e de saúde colhidas nos primeiros acompanhamentos, que são utilizadas como variáveis de exposição. RESULTADOS: A maior parte dos jovens da coorte foram acompanhados durante 23 anos de vida e distintas visitas. Os acompanhamentos que obtiveram maior êxito foram aqueles precedidos por um censo da cidade. Com este método foram localizados 87,2% em 1984 (idade média de 19 meses), 84,1% em 2006 (média 43 meses), e 77,4% em 2004-5 (média 23 anos). CONCLUSÕES: Estudos de coorte de nascimentos podem ser realizados com sucesso em países em desenvolvimento, e a metodologia empregada nesses estudos de ciclo vital permite estudar a influência de exposições precoces sobre a determinação das doenças da vida adulta.; OBJETIVO: Describir los métodos utilizados en el estudio longitudinal y acompañamiento de los niños nacidos en Pelotas (Sur de Brasil) en 1982. MÉTODOS: La cohorte fue iniciada con una investigación de salud perinatal de todos los 6.011 niños nacidos en las maternidades de Pelotas en 1982. Los 5.914 niños nacidos vivos fueron incluidos en los estudios de acompañamiento. Hasta 2004-5 fueron realizados ocho acompañamientos...

The Pelotas birth cohort study, Rio Grande do Sul, Brazil, 1982-2001

Victora,Cesar G.; Barros,Fernando C.; Lima,Rosângela C.; Behague,Dominique P.; Gonçalves,Helen; Horta,Bernardo L.; Gigante,Denise P.; Vaughan,J. Patrick
Fonte: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz Publicador: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/10/2003 EN
Relevância na Pesquisa
56.04%
Given the growing recognition of the importance of the life course approach for the determination of chronic diseases, birth cohort studies are becoming increasingly important. This paper describes the methods used in the 1982 Pelotas (Brazil) birth cohort study, one of the largest and longest studies of this type in developing countries. All 5,914 hospital births occurring in Pelotas in 1982 (over 99% of all deliveries) were studied prospectively. The main stages of the study took place in 1983, 1984, 1986, 1995, 1997, 2000, and 2001. More than two thousand variables are available for each subject who participated in all stages of the study. Recent phases of the study included the examination of 2,250 males when presenting for the army recruitment exam in 2000, the study of a 27% sample of men and women in 2001 through household visits, and the study of over 400 children born to the cohort women. Follow-up rates in the recent stages of the cohort were 78.9% for the army examination and 69.0% for the household visits. Ethnographic and oral health studies were conducted in sub-samples. Some recent results on blood pressure, adolescent pregnancy, and asthma are presented as examples of utilization of the data. Suggestions on lessons learned for other cohort studies are proposed.

Methodological aspects of the 1993 Pelotas (Brazil) birth cohort study

Victora,Cesar Gomes; Araújo,Cora Luiza Pavin; Menezes,Ana Maria Batista; Hallal,Pedro Curi; Vieira,Maria de Fátima; Neutzling,Marilda Borges; Gonçalves,Helen; Valle,Neiva Cristina; Lima,Rosangela Costa; Anselmi,Luciana; Behague,Dominique; Gigante,Denis
Fonte: Faculdade de Saúde Pública da Universidade de São Paulo Publicador: Faculdade de Saúde Pública da Universidade de São Paulo
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/02/2006 EN
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This paper describes the main methodological aspects of a cohort study, with emphasis on its recent phases, which may be relevant to investigators planning to carry out similar studies. In 1993, a population based study was launched in Pelotas, Southern Brazil. All 5,249 newborns delivered in the city's hospitals were enrolled, and sub-samples were visited at the ages of one, three and six months and of one and four years. In 2004-5 it was possible to trace 87.5% of the cohort at the age of 10-12 years. Sub-studies are addressing issues related to oral health, psychological development and mental health, body composition, and ethnography. Birth cohort studies are essential for investigating the early determinants of adult disease and nutritional status, yet few such studies are available from low and middle-income countries where these determinants may differ from those documented in more developed settings.

Methods used in the 1982, 1993, and 2004 birth cohort studies from Pelotas, Rio Grande do Sul State, Brazil, and a description of the socioeconomic conditions of participants' families

Barros,Aluísio J. D.; Santos,Iná S.; Matijasevich,Alicia; Araújo,Cora L.; Gigante,Denise P.; Menezes,Ana M. B.; Horta,Bernardo L.; Tomasi,Elaine; Victora,Cesar G.; Barros,Fernando C.
Fonte: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz Publicador: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2008 EN
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Three birth cohorts are currently being followed in Pelotas, Southern Brazil, in order to assess changes in birth conditions, growth, development, morbidity, and infant mortality, as well as the influence of pre- and perinatal factors on the subsequent morbidity of participants in their adult lives. We provide a description of the methodology used for the cohort studies that began in 1982, 1993, and 2004 in Pelotas, and a description of the economic conditions of the families involved. For the three cohorts, similar strategies were used to recruit babies born to mothers living in the municipality's urban area. These included daily visits to maternity hospitals where births were identified, mothers interviewed, and newborns examined. Over this time frame, there has been a significant reduction in the number of births due to declining fertility rates amongst the target population. Salaries (measured as a multiple of the minimum wage) were stable across cohorts, but quality of life indicators - such as the availability of piped water, flushing toilets and refrigerators - showed clear improvements. Mothers' levels of education improved markedly. Important changes in the demographic profile of risk factors and health outcomes are being recorded by the Pelotas cohorts.