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Avaliação da atividade antimicrobiana, citotóxica e capacidade sequestradora de radicais livres de extratos brutos do Cocos nucifera Linn; Evaluation of antimicrobial and cytotoxicity activity and free radical scavenging capacity of crude extracts of cocos nucifera Linn

Figueira, Cristiane do Nascimento Tavares
Fonte: Universidade Federal de Alagoas; Brasil; Programa de Pós-Graduação em Enfermagem; UFAL Publicador: Universidade Federal de Alagoas; Brasil; Programa de Pós-Graduação em Enfermagem; UFAL
Tipo: Dissertação
POR
Relevância na Pesquisa
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Cocos nucifera Linn is a tropical palm tree whose fruit is used for alimentary, cosmetics, handmade and medicinal purposes. However the research from other parts of this species is incipient. The researchs about therapeutic activities from plants used by population is encouraged by the Health World Organisation and, in Brazil, fomented by 10 thousand vegetable species cataloged and only 10% evaluated with respect to their biological activities and safety. The resolution No. 197/1997 of the Federal Council of Nursing endorses the use of plants in the practice of nursing care and linked to the need for alternatives against microbial multirresistance and oxidative diseases which are problems contemporaries of humanity. This preclinical experimental research was performed at the Master’s Program in Nursing at the Federal University of Alagoas in order to investigate the antimicrobial activity and cytotoxicity and free radical scavenging capacity of crude ethanol extracts of the leaves, stem and stalk's husk of Cocos nucifera L. (coconut palm) in vitro. It was evaluated the extract's antimicrobial activities against the Gram positive bacteria: S. aureus and Gram negative: E. coli and P. aeruginosa and C. albicans fungus by Àgar diffusion methods and identification of the Minimum Inhibitory Concentrations by microdilution. It was performed cytotoxicity assay in J774 lineage cells by MTT [3 - (4...