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Cardiovascular risk factors associated with migraine among the elderly with a low income: The Sao Paulo Ageing & Health Study (SPAH)

BENSENOR, Isabela M.; GOULART, Alessandra C.; LOTUFO, Paulo A.; MENEZES, Paulo R.; SCAZUFCA, Marcia
Fonte: SAGE PUBLICATIONS LTD Publicador: SAGE PUBLICATIONS LTD
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
96.02%
Background: To investigate the association between cardiovascular risk-factor profile and migraine in the elderly, we evaluated a population sample of ageing men and women (65 years or more) living in a low-income area in the city of Sao Paulo, Brazil. Patients and Methods: We investigated migraine status and cardiovascular profile from a baseline of 1450 participants (65-102 years of age) of the Sao Paulo Ageing & Health Study (SPAH), a longitudinal population-based study with low-income elderly in Brazil. The following age and sex-adjusted cardiovascular risk factors were analyzed: blood pressure, pulse pressure, serum total and high-density lipoprotein cholesterol, body mass index, smoking, history of hypertension, diabetes and the 10-year risk of myocardial infarction or coronary heart disease death based on the Framingham Risk Score. Results: The overall prevalence of migraine was 11.4%, and it was 3 times more frequent among women than men (15.3% vs 5.4%; P < 0.0001). Migraineurs were younger than non-migraineurs (mean age 70.6 years vs 72.1 years; P = 0.001, respectively). There was no statistically significant difference regarding the cardiovascular risk-factor profile after adjustment for age and sex among migraineurs and non-migraineurs. Only a decrease in the risk of hypertension among women (OR 0.58; 95% CI 0.38-0.90; P = 0.01) was also observed even after adjustment for age. Conclusions: Overall...

Fatores de risco cardiovascular em adolescentes estudantes da rede pública municipal de ensino de Brodowski-SP; Cardiovascular risk factors in adolescents from public schools in the city of Brodowski-SP.

Gonçalves, Valdelice Maria
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 01/06/2012 PT
Relevância na Pesquisa
96.05%
Introdução: As alterações metabólicas associadas ao sistema cardiovascular, em especial a doença arterial coronariana (DAC) secundária à aterosclerose, constituem as principais causas de morbidade e mortalidade no mundo. De forma semelhante ao que ocorre em adultos, os fatores de risco cardiovascular estão presentes em crianças e adolescentes como a obesidade, a obesidade abdominal e a hipertensão arterial. Objetivo: Estudar a presença de algumas variáveis consideradas fatores de risco cardiovascular em adolescentes, matriculados em rede publica de ensino de Brodowski-SP. Metodologia: Foi realizado um estudo transversal com 668 escolares de 10 a 16 anos da rede pública municipal de ensino de Brodowski-SP. Dados de antropometria foram coletados (peso, altura e circunferência da cintura).Os adolescentes foram avaliados de acordo com seu estado nutricional segundo os escores IMC para a idade, a composição corporal foi avaliada pela bioimpedância, a pressão arterial foi avaliada por aparelho automático. Os dados foram analisados por meio do Teste Exato de Fisher e Regressão Logística (Odds Ratio Bruto e Ajustada). Resultados: A faixa etária predominante foi de 11 a 13 anos de idade. Os dados sobre sobrepeso e obesidade foram alarmantes e perfazem um total de 32...

Associação dos fatores de risco cardiovasculares com os tipos de demência em diabéticos; ASSOCIATION OF CARDIOVASCULAR RISK FACTORS WITH TYPES OF DEMENTIA IN DIABETIC PATIENTS

Degiovanni, Gabriel Carvalho
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 30/10/2013 PT
Relevância na Pesquisa
95.99%
O crescente aumento no número de idosos na população mundial aumenta a preocupação, pelos profissionais da saúde, com relação à prevenção e manejo de doenças associadas ao envelhecimento. A demência, uma das doenças mais comuns e mais devastadoras em idosos, incide em 4,6 milhões de casos em todo o mundo e manifesta-se em idosos acima de 65 anos e principalmente acima de 85 anos de idade. Os dois tipos mais comuns de demência é a doença de Alzheimer (DA), seguida da demência vascular (DV), as quais partilham muitas características comuns patológicas, sintomáticas e neuroquímicas. Entre os principais fatores de risco para demência estão a idade, baixa escolaridade, hipertensão (HAS), cardiopatias, dislipidemias (DLP), sobrepeso/obesidade, genética, tabagismo, etilismo, acidente vascular cerebral (AVC) e o diabetes. Diante da sobreposição de causas e fatores de risco para as demências mais comuns, a identificação das alterações cognitivas associada à identificação de doenças cardiovasculares, seria extremamente importante. A associação dos principais fatores de risco cardiovasculares (FRCV) com a idade e o tipo das demências foi avaliada neste estudo, em 2 grupos de idosos diabéticos com DA (n=47) e demência mista ou vascular (n=49). Os resultados foram obtidos pelo teste t-student...

Treinamento físico e fatores de risco cardiovascular em homens de meia-idade; Physical training and cardiovascular risk factors in middle-aged

Giovana Vergínia de Souza
Fonte: Biblioteca Digital da Unicamp Publicador: Biblioteca Digital da Unicamp
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 10/09/2010 PT
Relevância na Pesquisa
96.01%
A inatividade física aliada ao envelhecimento é um dos principais fatores de risco para as doenças cardiovasculares (DCV). A associação do treinamento com pesos (TP) e aeróbio (TA), ou seja, o treinamento concorrente (TC) tem sido recomendado como prevenção destes fatores de risco cardiovascular. Desta forma o objetivo deste estudo foi comparar as respostas de três tipos de treinamento físico sobre circunferência de cintura (CC), perfil lipídico (HDL, LDL e TG), glicose plasmática, pressão arterial (PA), aptidão aeróbia e força muscular em homens não ativos de meia-idade. Os voluntários (n=50) foram subdivididos em quatro grupos, sendo: três grupos submetidos a 16 semanas de treinamento: aeróbio (TA, n =15), com pesos (TP, n=10) e concorrente (TC, n=13) e grupo controle (GC, n=12), o qual não realizou nenhum tipo de atividade física. Os principais achados deste estudo mostraram após os períodos de treinamento alterações importantes quanto a redução da CC nos grupos TA e TC; reduções no LDL para TP e TC e no triglicerídeos (TG) para todos os grupos treinamento; para o HDL ocorreu aumento apenas para o TA. Para as variáveis funcionais, ocorreram aumentos para o *VO2pico* para os grupos TA e TC, e aumentos na força máxima de membros superiores para TP e TC e dos membros inferiores para todos os grupos treinamento. Nossa hipótese de que o TC realizado com duração da sessão e frequencia semanal similar ao TA e ao TP resulte em respostas mais efetivas no controle dos fatores de risco de doenças cardiovasculares foi confirmada pelos presentes achados. Novas propostas de periodizações de treinamento concorrente ainda são necessárias...

Analysis of the Association Between Apolipoprotein E Polymorphism and Cardiovascular Risk Factors in an Elderly Population with Longevity

Schwanke,Carla Helena Augustin; Cruz,Ivana Beatrice Mânica da; Leal,Ney Furhmann; Scheibe,Rosane; Moriguchi,Yukio; Moriguchi,Emílio Hideyuki
Fonte: Sociedade Brasileira de Cardiologia - SBC Publicador: Sociedade Brasileira de Cardiologia - SBC
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/2002 EN
Relevância na Pesquisa
95.99%
OBJECTIVE: To establish the allelic and genotypic frequencies related to apolipoprotein E (ApoE) polymorphism and association of the genotypes with risk factors and cardiovascular morbidity in an elderly population with longevity. METHODS: We analyzed 70 elderly patients aged 80 years or more who were part of the Projeto Veranópolis. We used the gene amplification technique through the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and cleavage with the restriction enzyme Hha I to identify the ApoE genotypes. The most frequent genotypes were compared considering biological variables and cardiovascular risks and morbidity. RESULTS: The frequencies of the E2, E3, and E4 alleles were 0.05, 0.84, and 0.11, respectively, and of the genotypes were as follows: E3E3 (0.70), E3E4 (0.22), E2E3 (0.06), and E2E2 (0.02). Individuals with the E3E4 had a mean age greater than those with the E3E3. No association was observed between the genotypes and the variables analyzed, except for obesity, which was associated with the E3E3 genotype. Individuals with the E3E4 genotype had high levels of LDL-cholesterol and fibrinogen as compared with those with the E3E3 genotype. CONCLUSION: The results suggest that the E4E4 genotype may be associated with early mortality. A balance between the protective or neutral factors and the cardiovascular risk factors may occur among the individuals with different genotypes...

Assessment of cardiovascular risk factors in a rural community in the Brazilian state of Bahia

Matos,André Costa; Ladeia,Ana Marice
Fonte: Sociedade Brasileira de Cardiologia - SBC Publicador: Sociedade Brasileira de Cardiologia - SBC
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/09/2003 EN
Relevância na Pesquisa
96.01%
OBJECTIVE: To assess the frequency of cardiovascular risk factors in the rural community of Cavunge, in the Brazilian state of Bahia. METHODS: A cross-sectional study was carried out with 160 individuals (age > 19 years) randomly drawn from those listed in the population census of the Cavunge Project. The following parameters were studied: arterial hypertension, dyslipidemia, diabetes, obesity, smoking, waist-hip ratio (WHR), physical activity, and overall cardiovascular risk classified according to the Framingham score. The assessing parameters used were those established by the III Brazilian Consensus on Hypertension and the II Brazilian Consensus on Dyslipidemia. RESULTS: Of the randomly drawn individuals, 126 with a mean age of 46.6 + 19.7 years were included in the study, 43.7% of whom were males. The frequency of arterial hypertension was 36.5%; 20.4% of the individuals had cholesterol levels >240 mg/dL; 31.1% of the individuals had LDL-C levels > 130 mg/dL; 4% were diabetic; and 39.7% had a high-risk Framingham score. Abdominal obesity was observed in 41.3% of the population and in 57.7% of the females. High caloric-expenditure (HCE) physical activities were performed by 56.5% of the individuals. The HCE group had a greater frequency of normal triglyceride levels (63% vs 44%; P=0.05)...

Cardiovascular risk factors in a population of Brazilian schoolchildren

Rodrigues,A.N.; Moyses,M.R.; Bissoli,N.S.; Pires,J.G.P.; Abreu,G.R.
Fonte: Associação Brasileira de Divulgação Científica Publicador: Associação Brasileira de Divulgação Científica
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2006 EN
Relevância na Pesquisa
96%
Epidemiological and clinical evidence suggests that a judicious diet, regular physical activity and blood pressure (BP) monitoring must start in early childhood to minimize the impact of modifiable cardiovascular risk factors. This study was designed to evaluate BP and metabolic parameters of schoolchildren from Vitória, Espírito Santo State, Brazil, and correlate them with cardiovascular risk factors. The study was conducted on 380 students aged 10-14 years (177 boys, 203 girls) enrolled in public schools. Baseline measurements included body mass index, BP and heart rate. The students were submitted to exercise spirometry on a treadmill. VO2max was obtained from exercise testing to voluntary exhaustion. Fasting serum total cholesterol (TC), LDL-C, HDL-C, triglycerides (TG), and glucose were measured. Nine point nine percent of the boys and 11.7% of the girls were hypertensive or had pre-hypertensive levels. There was no significant correlation between VO2max and TC, LDL-C, or TG in prepubertal children, but a slight negative correlation was detected in post-pubertal boys for HDL-C and TG. In addition, children with hypertension (3.4%) or pre-hypertensive levels (6.6%) also had comorbidity for overweight and blood lipid abnormalities (14% for triglycerides...

Peroxiredoxin isoforms are associated with cardiovascular risk factors in type 2 diabetes mellitus

El Eter,E.; Al-Masri,A.A.
Fonte: Associação Brasileira de Divulgação Científica Publicador: Associação Brasileira de Divulgação Científica
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/05/2015 EN
Relevância na Pesquisa
96.04%
The production of oxygen free radicals in type 2 diabetes mellitus contributes to the development of complications, especially the cardiovascular-related ones. Peroxiredoxins (PRDXs) are antioxidant enzymes that combat oxidative stress. The aim of this study was to investigate the associations between the levels of PRDX isoforms (1, 2, 4, and 6) and cardiovascular risk factors in type 2 diabetes mellitus. Fifty-three patients with type 2 diabetes mellitus (28F/25M) and 25 healthy control subjects (7F/18M) were enrolled. We measured the plasma levels of each PRDX isoform and analyzed their correlations with cardiovascular risk factors. The plasma PRDX1, -2, -4, and -6 levels were higher in the diabetic patients than in the healthy control subjects. PRDX2 and -6 levels were negatively correlated with diastolic blood pressure, fasting blood sugar, and hemoglobin A1c. In contrast, PRDX1 levels were positively correlated with low-density lipoprotein and C-reactive protein levels. PRDX4 levels were negatively correlated with triglycerides. In conclusion, PRDX1, -2, -4, and -6 showed differential correlations with a variety of traditional cardiovascular risk factors. These results should encourage further research into the crosstalk between PRDX isoforms and cardiovascular risk factors.

Does calcium intake affect cardiovascular risk factors and/or events?

Torres,Márcia Regina Simas Gonçalves; Sanjuliani,Antonio Felipe
Fonte: Faculdade de Medicina / USP Publicador: Faculdade de Medicina / USP
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/07/2012 EN
Relevância na Pesquisa
96.03%
Dietary intervention is an important approach in the prevention of cardiovascular disease. Over the last decade, some studies have suggested that a calcium-rich diet could help to control body weight, with anti-obesity effects. The potential mechanism underlying the impact of calcium on body fat has been investigated, but it is not fully understood. Recent evidence has also suggested that a calcium-rich diet could have beneficial effects on other cardiovascular risk factors, such as insulin resistance, dyslipidemia, hypertension and inflammatory states. In a series of studies, it was observed that a high intake of milk and/or dairy products (the main sources of dietary calcium) is associated with a reduction in the relative risk of cardiovascular disease. However, a few studies suggest that supplemental calcium (mainly calcium carbonate or citrate) may be associated with an increased risk of cardiovascular events. This review will discuss the available evidence regarding the relationship between calcium intake (dietary and supplemental) and different cardiovascular risk factors and/or events.

Cardiovascular risk factors in women who had hypertensive disorders late in pregnancy: a cohort study

Hermes, W.; Franx, A.; van Pampus, M.; Bloemenkamp, K.; Bots, M.; van der Post, J.; Porath, M.; Ponjee, G.; Tamsma, J.; Mol, B.; de Groot, C.
Fonte: Elsevier Publicador: Elsevier
Tipo: Artigo de Revista Científica
Publicado em //2013 EN
Relevância na Pesquisa
96%
OBJECTIVE: The purpose of this study was to determine cardiovascular risk factors in women with a history of hypertensive pregnancy disorders at term (HTP) 2.5 years after pregnancy. STUDY DESIGN: In a multicenter cohort study in The Netherlands from June 2008 through November 2010, cardiovascular risk factors were compared between women with a history of HTP (HTP cohort, n = 306) and women with a history of normotensive pregnancies at term (NTP cohort, n = 99). HTP women had participated in a randomized, longitudinal trial assessing the effectiveness of induction of labor in women with hypertensive pregnancy disorders at term. All women were assessed 2.5 years after pregnancy for blood pressure, anthropometrics, glucose, glycosylated hemoglobin, insulin, homeostatic model assessment score, total cholesterol, high-density lipoprotein cholesterol, triglycerides, high-sensitivity C-reactive protein, and microalbumin and metabolic syndrome. RESULTS: After a mean follow-up period of 2.5 years, hypertension (HTP, 34%; NTP, 1%; P < .001) and metabolic syndrome (HTP, 25%; NTP, 5%; P < .001) were more prevalent in HTP women compared with NTP women. HTP women had significantly higher systolic and diastolic blood pressure, higher body mass index...

Prevalence, geographic distribution, and geographic variability of major cardiovascular risk factors in Spain: pooled analysis of data from population-based epidemiological studies: the ERICE study

Gabriel, Rafael; Alonso, Margarita; Segura Fragoso, Antonio; Tormo, María José; Artigao, Luis M.; Banegas Banegas, José Ramón; Brotons, Carlos; Elosua, Roberto; Fernández-Cruz, Antonio; Muñiz, Javier; Reviriego, Blanca; Rigo, Fernando
Fonte: Elsevier Publicador: Elsevier
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
96.08%
[Abstract] Introduction and objectives. To determine the prevalence and geographic distribution of major cardiovascular risk factors in the Spanish population. To investigate whether geographic variability exists. Methods. Data were pooled from eight cross-sectional epidemiologic studies carried out in Spain between 1992 and 2001 whose methodological quality satisfied predefined criteria. Individual data were reassessed and analyzed by age group (20-44 years, 45-64 years, and [.greaterequal] 65 years), sex, and geographic area. The study population included 19 729 individuals. Mean values and unadjusted and adjusted prevalence rates were derived for various risk factors. Results. The most common cardiovascular risk factors in the Spanish population were, in descending order: hypercholesterolemia (ie, total cholesterol >200 mg/dL) in46.7%, hypertension in 37.6%, smoking in 32.2%, obesity in 22.8%, and diabetes mellitus in 6.2%. The mean values for blood pressure, body mass index, high-density lipoprotein cholesterol, and glycemia varied considerably with age, sex, and geographic area. The highest levels of cardiovascular risk factors were observed in Mediterranean and south-eastern areas of the country and the lowest, in northern...

Longitudinal displacement of the carotid wall and cardiovascular risk factors: associations with aging, adiposity, blood pressure and periodontal disease independent of cross-sectional distensibility and intima-media thickness

Zahnd, G.; Vray, D.; Seruslat, A.; Alibay, D.; Bartold, P.; Brown, A.; Durand, M.; Jamieson, L.; Kapellas, K.; Maple-Brown, L.; O'Dea, K.; Moulin, P.; Celermajer, D.; Skilton, M.
Fonte: Elsevier Science Inc Publicador: Elsevier Science Inc
Tipo: Artigo de Revista Científica
Publicado em //2012 EN
Relevância na Pesquisa
96.07%
The recently discovered longitudinal displacement of the common carotid arterial wall (i.e., the motion along the same plane as the blood flow), may be associated with incident cardiovascular events and represents a novel and relevant clinical information. At present, there have only been a few studies that have been conducted to investigate this longitudinal movement. We propose here a method to assess noninvasively the wall bi-dimensional (two-dimensional [2-D], cross-sectional and longitudinal) motion and present an original approach that combines a robust speckle tracking scheme to guidance by minimal path contours segmentation. Our method is well suited to large clinical population studies as it does not necessitate strong imaging prerequisites. The aim of this study is to describe the association between the longitudinal displacement of the carotid arterial wall and cardiovascular risk factors, among which periodontal disease. Some 126 Indigenous Australians with periodontal disease, an emerging risk factor, and 27 healthy age- and sex-matched non-indigenous control subjects had high-resolution ultrasound scans of the common carotid artery. Carotid intima-media thickness and arterial wall 2-D motion were then assessed using our method in ultrasound B-mode sequences. Carotid longitudinal displacement was markedly lower in the periodontal disease group than the control group (geometric mean (IQR): 0.15 mm (0.13) vs. 0.42 mm (0.30)...

Induction of labour or expectant monitoring in hypertensive pregnancy disorders at term: do women's postpartum cardiovascular risk factors differ between the two strategies?

Hermes, W.; Koopmans, C.; van Pampus, M.; Franx, A.; Bloemenkamp, K.; van der Post, J.; Porath, M.; Tamsma, J.; Mol, B.; de Groot, C.
Fonte: Elsevier Science Ireland Publicador: Elsevier Science Ireland
Tipo: Artigo de Revista Científica
Publicado em //2013 EN
Relevância na Pesquisa
96.03%
OBJECTIVE: Cardiovascular disease (CVD) is the leading cause of death in women in the western world. Several studies have described the association between hypertensive pregnancy disorders and CVD in later life. Our aim was to compare postpartum cardiovascular risk factors in women who had a shorter and women who had a longer exposure to endothelial activation during their term hypertensive pregnancy. STUDY DESIGN: We studied a subsample of women with pregnancy-induced hypertension or mild preeclampsia at term, who had participated in the randomized HYPITAT trial comparing induction of labour (IOL cohort) (n=110) or expectant monitoring (EM cohort) (n = 91). We assessed, 2.5 years postpartum, cardiovascular risk factors, i.e. blood pressure, anthropometrics, glucose, HbA1C, insulin, HOMA score, total cholesterol, HDL cholesterol, triglycerides, high sensitive CRP, micro-albumin and metabolic syndrome, and compared these risk factors between the induction and expectant groups. RESULTS: The mean time from randomization to delivery was 3.3 days in the induction group and 10.3 days in the expectant group (p<.001), generating a difference in exposure of 7 days. After a mean follow-up period of 2.5 years, the prevalence of hypertension (IOL 34%; EM 37%...

Hypertension and clustering of cardiovascular risk factors in a community in Southeast Brazil: the Bambuí Health and Ageing Study

Barreto,Sandhi Maria; Passos,Valéria Maria Azeredo; Firmo,Josélia Oliveira Araújo; Guerra,Henrique Leonardo; Vidigal,Pedro Guatimosim; Lima-Costa,Maria Fernanda Furtado
Fonte: Sociedade Brasileira de Cardiologia - SBC Publicador: Sociedade Brasileira de Cardiologia - SBC
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2001 EN
Relevância na Pesquisa
95.96%
OBJECTIVE - A population-based prospective study was analysed to: a) determine the prevalence of hypertension; b) investigate the clustering of other cardiovascular risk factors and c) verify whether older differed from younger adults in the pattern of clustering. METHODS - The data comprised a representative sample of the population of Bambuí, Brazil. Multiple logistic regression was used to investigate the independent association between hypertension and selected factors. RESULTS - A total of 820 younger adults (82.5%) and 1494 older adults (85.9%) participated in this study. The overall prevalence of hypertension was 24.8% (SE=1.4 %), being higher in women (26.9±1.5%) than in men (22.0± 1.7%) (p=0.033). Hypertension was positively and significantly associated with physical inactivity, overweight, hypercholesterolemia hyperglycemia and hypertriglyceridemia. The coexistence of hypertension with 4 or more of these risk factors occurred 6 times more than expected by chance, after adjusting for age and sex (OR=6.3; 95%CI: 3.4-11.9). The pattern of risk factor clustering in hypertensive individuals differed with age. CONCLUSION - Our results reinforce the need to increase detection and treatment of hypertension and to approach patients' global risk profiles.

Cardiovascular risk factors in outpatients with bipolar disorder: a report from the Brazilian Research Network in Bipolar Disorder

Gomes,Fabiano A.; Almeida,Karla M.; Magalhães,Pedro V.; Caetano,Sheila C.; Kauer-Sant'Anna,Márcia; Lafer,Beny; Kapczinski,Flávio
Fonte: Associação Brasileira de Psiquiatria - ABP Publicador: Associação Brasileira de Psiquiatria - ABP
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/2013 EN
Relevância na Pesquisa
96.03%
Objective: Bipolar disorder (BD) is associated with significant morbidity and mortality due to comorbid general medical conditions, particularly cardiovascular disease. This study is the first report of the Brazilian Research Network in Bipolar Disorder (BRN-BD) that aims to evaluate the prevalence and clinical correlates of cardiovascular risk factors among Brazilian patients with BD. Methods: A cross-sectional study of 159 patients with DSM-IV BD, 18 years or older, consecutively recruited from the Bipolar Research Program (PROMAN) in São Paulo and the Bipolar Disorder Program (PROTAHBI) in Porto Alegre. Clinical, demographic, anthropometric, and metabolic variables were systematically assessed. Results: High rates of smoking (27%), physical inactivity (64.9%), alcohol use disorders (20.8%), elevated fasting glucose (26.4%), diabetes (13.2%), hypertension (38.4%), hypertriglyceridemia (25.8%), low HDL-cholesterol (27.7%), general (38.4%) and abdominal obesity (59.1%) were found in the sample. Male patients were more likely to have alcohol use disorders, diabetes, and hypertriglyceridemia, whereas female patients showed higher prevalence of abdominal obesity. Variables such as medication use pattern, alcohol use disorder, and physical activity were associated with selected cardiovascular risk factors in the multivariable analysis. Conclusion: This report of the BRN-BD provides new data regarding prevalence rates and associated cardiovascular risk factors in Brazilian outpatients with BD. There is a need for increasing both awareness and recognition about metabolic and cardiovascular diseases in this patient population.

Does calcium intake affect cardiovascular risk factors and/or events?

Torres, Márcia Regina Simas Gonçalves; Sanjuliani, Antonio Felipe
Fonte: Universidade de São Paulo. Faculdade de Medicina Publicador: Universidade de São Paulo. Faculdade de Medicina
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; Formato: application/pdf
Publicado em 01/07/2012 ENG
Relevância na Pesquisa
96.03%
Dietary intervention is an important approach in the prevention of cardiovascular disease. Over the last decade, some studies have suggested that a calcium-rich diet could help to control body weight, with anti-obesity effects. The potential mechanism underlying the impact of calcium on body fat has been investigated, but it is not fully understood. Recent evidence has also suggested that a calcium-rich diet could have beneficial effects on other cardiovascular risk factors, such as insulin resistance, dyslipidemia, hypertension and inflammatory states. In a series of studies, it was observed that a high intake of milk and/or dairy products (the main sources of dietary calcium) is associated with a reduction in the relative risk of cardiovascular disease. However, a few studies suggest that supplemental calcium (mainly calcium carbonate or citrate) may be associated with an increased risk of cardiovascular events. This review will discuss the available evidence regarding the relationship between calcium intake (dietary and supplemental) and different cardiovascular risk factors and/or events.

Fatores de risco cardiovascular, declínio cognitivo e alterações cerebrais detectadas através de técnicas de neuroimagem; Cognitive decline, cardiovascular risk factors, and neuroimaging abnormalities

Alves, Tânia Corrêa de Toledo Ferraz; Wajngarten, Mauricio; Busatto Filho, Geraldo
Fonte: Universidade de São Paulo. Faculdade de Medicina. Instituto de Psiquiatria Publicador: Universidade de São Paulo. Faculdade de Medicina. Instituto de Psiquiatria
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; Formato: application/pdf
Publicado em 01/06/2005 POR
Relevância na Pesquisa
96.09%
Diversos estudos têm demonstrado associação entre fatores de risco cardiovascular e desenvolvimento de declínio cognitivo. Também há evidências do aumento das taxas de morbimortalidade em pacientes com doenças cardiovasculares e déficit cognitivo. Dentre os fatores de risco cardiovascular, hipertensão arterial e insuficiência cardíaca apresentaram forte associação com a presença de déficit cognitivo, entretanto os mecanismos cerebrais subjacentes não foram totalmente esclarecidos. Nos pacientes cardiopatas, o prejuízo cognitivo se dá principalmente nos aspectos de memória (fixação e aprendizado) e processamento das informações. Nesse artigo, revisa-se os achados de neuroimagem observados em amostras de pacientes com fatores de risco cardiovascular com declínio cognitivo, incluindo achados regionais de anormalidades volumétricas, hiperintensidade de substância branca, acidentes vasculares silenciosos, infartos lacunares e déficits funcionais na perfusão cerebral global (associada à redução do débito cardíaco) e perfusão cerebral regional. Discute-se, também, as implicações destes achados para a fisiopatologia do declínio cognitivo e suas aplicações clínicas. Finalmente, aborda-se o potencial de utilização de novas técnicas de imagem em estudos futuros na avaliação das alterações estruturais e funcionais associadas a fatores de riscos vasculares em amostras de base populacional.; Several research studies have shown associations between cardiovascular risk factors and the development of cognitive decline. There is also evidence of an increased rate of morbidity and mortality in subjects with cardiovascular diseases with concomitant cognitive decline. Congestive heart failure and hypertension...

Circulating adipocytokines in morbid obese patients, relation with cardiovascular risk factors and anthropometric parameters

de Luis,D. A.; González Sagrado,M.; Conde,R.; Aller,R.; Izaola,O.; Castro,M.ª J.
Fonte: Nutrición Hospitalaria Publicador: Nutrición Hospitalaria
Tipo: info:eu-repo/semantics/article; journal article; info:eu-repo/semantics/publishedVersion Formato: text/html; application/pdf
Publicado em 01/02/2011 ENG
Relevância na Pesquisa
95.99%
Background: Obesity and insulin resistance are associated with cardiovascular risk factors, including adipocytokines. The aim of the present study was to explore the relation of circulating adipocytokines with cardiovascular risk and anthropometric parameters in morbid obese patients. Subjects: A population of 65 morbid obese patients was analyzed in a prospective way. A biochemical, anthropometric and dietary evaluation was realized. Results: In the multivariate analysis with resistin as dependent variable, the BMI remained in the model (F = 16.6; p < 0.05), with an increase of 0.23 (CI 95%: 0.06-0.41) ng/ml with each point of BMI. In a second model with adiponectin as dependent variable, the age remained in the model (F = 4.46; p < 0.05), with an increase of 3.62 (CI 95%: 0.05-7.21) ng/ml with each year. In the third model with interleukin 6 as dependent variable, the HOMA, CRP and weight remained in the model (F = 8.8; p < 0.01), with an increase of 0.26 (CI 95%: 0.05-0.47) pg/ml with each point of HOMA, an increase of 0.43 (CI 95%: 0.10-0.76) pg/ml with each 1 mg/dl of CRP and an increase of 0.13 (CI 95%: 0.05-0.21) pg/ml with each kg of weight. In the fourth model with TNF-alpha as dependent variable, resistin, IL-6 and weight remained in the model (F = 5.2; p < 0.01)...

Lipid profile and cardiovascular risk factors among first-year Brazilian university students in São Paulo

Costa Silva Zemdegs,J.; Barreto Corsi,L.; Castro Coelho,L. De; Duarte Pimentel,G.; Toyomi Hirai,A.; Sachs,A.
Fonte: Nutrición Hospitalaria Publicador: Nutrición Hospitalaria
Tipo: info:eu-repo/semantics/article; journal article; info:eu-repo/semantics/publishedVersion Formato: text/html; application/pdf
Publicado em 01/06/2011 ENG
Relevância na Pesquisa
96.04%
Background/aims: The surveillance of cardiovascular risk factors has been recommended worldwide. The current study is aimed to estimate the prevalence of cardiovascular risk factors among first-year students from a public university in the city of Sao Paulo, Brazil. Methods: A cross-sectional study of 56 first-year students, of both genders, was performed. Information about demographic characteristics, family history of chronic diseases, smoking, and physical activity was obtained by means of a standardised questionnaire. Anthropometrical parameters (BMI, waist circumference, body fat percentage), metabolic parameters (glycaemia, serum lipid profile), and dietary data (total energy intake, percentage of total energy from macronutrients, cholesterol and dietary fiber) were assessed. Results: The risk of cardiovascular diseases was characterised by family history of cardiovascular diseases (44.6%), smoking (10.7%), physical inactivity (35.7%), borderline high total cholesterol and LDL-c levels (16.1% and 5.4, respectively), decreased HDL-c levels (8.9%), increased triglyceride levels (8.9%), and overweight and obesity (17.8% and 7.1%, respectively). The diet of the students was inadequate: it was high in fat and protein, and low in carbohydrate and dietary fibre. Conclusions: The prevalence of risk factors for cardiovascular diseases in young adults draws attention to the need to adopt preventive plans in the university setting.

Double blind randomized clinical trial controlled by placebo with a FOS enriched cookie on saciety and cardiovascular risk factors in obese patients

Luis,D. A. de; Fuente,B. de la; Izaola,O.; Aller,R.; Gutiérrez,S.; Morillo,María
Fonte: Nutrición Hospitalaria Publicador: Nutrición Hospitalaria
Tipo: info:eu-repo/semantics/article; journal article; info:eu-repo/semantics/publishedVersion Formato: text/html; application/pdf
Publicado em 01/02/2013 ENG
Relevância na Pesquisa
96%
Introduction: It is essential to determine which snack foods are most affective for appetite control. The objective of the current study was to assess the responses of two different cookies on satiety and cardiovascular risk factors. Material and Methods: 38 patients were randomized: group I (FOS enriched cookie, n=19) and group II (control cookie, n=19). Previous and after 1 month , the subjects rated their feelings of satiety/hunger with a test meal of 5 cookies. Results: After the test meal, the basal area under curve of the first hunger/satiety score was higher with satiety cookie than with control cookie, the data after 1 month of treatment was higher with satiety cookie than with control cookie, too. The score was higher than the fasting level for 20 minutes with satiety cookie and for 40 minutes with the same cookie, too. In satiety group, these scores (20 min and 40 min) were higher than control group before and after 1 month of treatment. The results were in the same way with the 100 mm 5-point visual satiety scale. Cardiovascular risk factors and dietary intake remained unchanged after dietary intervention. Conclusion: A FOS enriched cookie produced greater ratings of satiety than a control cookie, without effects on cardiovascular risk factors or dietary intakes.