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Aplicabilidade de tarefas de memória autobiográfica na investigação dos efeitos do envelhecimento; Applicability of autobiographical memory tasks on the investigation of the effects of aging

Regina, Ana Carolina Brocanello
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 09/05/2014 PT
Relevância na Pesquisa
47.11%
INTRODUÇÃO: A memória autobiográfica é um tipo de memória episódica, que abrange os aspectos perceptuais, afetivos e espaço-temporais de um evento. Tais aspectos são organizados em representações que compõem uma história pessoal, sendo portanto fundamentais para a formação da identidade. Esse tipo de lembrança é uma construção transitória e dinâmica gerada a partir de uma base de conhecimento subjacente e esta base é armazenada em diferentes níveis de especificidade de detalhes. Por possuir grande conteúdo episódico, que é dependente das regiões frontais e temporomediais, áreas cerebrais conhecidas por sofrerem alterações significativas com o avanço da idade, é um sistema de memória que parece apresentar declínio com o avanço da idade. O presente estudo procurou investigar a relação entre a memória autobiográfica e o envelhecimento em 57 voluntários saudáveis, que foram divididos em dois grupos: adultos jovens (18 a 50 anos) e adultos mais velhos (51 a 75 anos). METODOLOGIA: A investigação utilizou uma entrevista de memória autobiográfica constituída de 5 eventos públicos marcantes (flashbulb memories), 4 estímulos de valência (positiva e negativa) e 1 evento importante ocorrido no último ano. As entrevistas foram avaliadas e pontuadas de acordo com sistema de categorização dos detalhes relatados em episódicos e semânticos. Também foi usada uma bateria de testes neuropsicológicos composta por 7 testes agrupados em 5 domínios cognitivos destinados a avaliar respectivamente: velocidade de processamento da informação...

Adolescência: Ideação suicida, depressão, desesperança e memórias autobiográficas

Costa, Inês Alexandra Nabiça Cardoso da
Fonte: ISPA - Instituto Universitário das Ciências Psicológicas, Sociais e da Vida Publicador: ISPA - Instituto Universitário das Ciências Psicológicas, Sociais e da Vida
Tipo: Dissertação de Mestrado
Publicado em //2012 SPA
Relevância na Pesquisa
47.15%
Dissertação de Mestrado em Psicologia Clínica; O nosso estudo procurou perceber se a depressão, a desesperança e a ideação suicida estavam correlacionadas e se o tipo de recordação de memórias autobiográficas para as palavras família, amigos e escola, ao nível da especificidade, valência e categorias, influencia as primeiras três variáveis. Para tal, foi aplicada uma tarefa de memórias autobiográficas onde era pedido para recordar três memórias referentes às palavras família, escola e amigos, a Escala de auto-avaliação da Depressão (DSRS), a Escala da Desesperança de Beck (BHS) e o questionário da ideação suicida (QIS). Os resultados sugeriram que a ideação suicida, a depressão e a desesperança estão positiva e fortemente correlacionadas. Sugeriram ainda que a recordação das memórias autobiográficas referentes às palavras família e amigos não influenciaram a ideação suicida, a depressão nem a desesperança. Para a recordação das memórias autobiográficas referentes à palavra escola, foi possível verificar que a variável categoria tem apenas um efeito principal na depressão. Embora os resultados referentes à especificidade e valência das memórias autobiográficas para as palavras família...

Valência emocional das memórias autobiográficas e a personalidade : Emoção, personalidade e memórias autobiográficas

Ramires, Ana Sofia Lopes
Fonte: Instituto Universitário de Ciências Psicológicas, Sociais e da Vida Publicador: Instituto Universitário de Ciências Psicológicas, Sociais e da Vida
Tipo: Dissertação de Mestrado
Publicado em //2014 POR
Relevância na Pesquisa
47.26%
Dissertação de mestrado apresentada ao ISPA - Instituto Superior; É muito vasta a literatura no campo das memórias autobiográficas. No entanto, o impacto da personalidade na evocação das memórias autobiográficas é ainda, pouco claro. O Objectivo desta investigação é avaliar se os domínios da personalidade vão influenciar a valência emocional das memórias autobiográficas evocadas. A metodologia prende-se com a aplicação de escalas clínicas como o BDI (Beck, 1974), o BSI (Canavarro, 1999), Inventário de Personalidade NEO-PI-R (McCrae & Costa, 1992) e Tarefa de Memórias Autobiográficas (Cáudio,2004), que visam a avaliação das memórias autobiográficas e determinam os domínios de personalidade que maior influencia têm no processo de evocação de memórias autobiográficas. Determina-se que, apesar de não serem significativos, os resultados apontam no sentido esperado e que existe uma tendência para uma maior evocação de memórias autobiográficas de valência emocional positiva do que negativa; As mulheres são tendencialmente mais rápidas no processo de evocação; Mulheres evocam maior número de memórias autobiográficas do que os homens; Quanto maiores os níveis de neuroticismo, maior o número de memórias autobiográficas de valência emocional negativa evocadas e por fim...

Hippocampal activation for autobiographical memories over the entire lifetime in healthy aged subjects: an fMRI study

Viard, Armelle; Piolino, Pascale; Desgranges, Beatrice; Chetelat, Gael; Lebreton, Karine; Landeau, Brigitte; Young, Alan; De La Sayette, Vincent; Eustache, Francis
Fonte: Oxford University Press Publicador: Oxford University Press
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
46.98%
We used functional MRI to determine the cerebral structures required during the recollection of episodic autobiographical memories according to five time-periods covering the whole lifespan to test the two concurring models of memory consolidation which propose either a temporary (standard model) or a permanent (multiple-trace model) role of the hippocampus in episodic memory retrieval. The experimental paradigm was specially designed to engage subjects (67.17 ± 5.22 years old) in the retrieval of episodic autobiographical memories, whatever the time-period, from personally relevant cues selected by questioning a family member. Moreover, the nature of the memories was checked at debriefing by means of behavioral measures to control the degree of episodicity. Behavioral data showed that recollected memories were characterized by specificity and details whatever their remoteness. Main neuroimaging data (SPM99) revealed the activation of a network including the left superior frontal gyri, bilateral precuneus/posterior cingulate and lingual gyri, left angular gyrus and left hippocampus, although the subtraction analyses detected subtle differences between certain time-periods. Small volume correction (SVC) centered on the hippocampus detected left hippocampal activation for all time-periods and additional right hippocampal activation for the intermediate periods. Further confirmation was provided by using a three-way ANOVA on BOLD values which revealed hippocampal activation...

New Episodic Learning Interferes with the Reconsolidation of Autobiographical Memories

Schwabe, Lars; Wolf, Oliver T.
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
Publicado em 21/10/2009 EN
Relevância na Pesquisa
46.86%
It is commonly assumed that, with time, an initially labile memory is transformed into a permanent one via a process of consolidation. Yet, recent evidence indicates that memories can return to a fragile state again when reactivated, requiring a period of reconsolidation. In the study described here, we found that participants who memorized a story immediately after they had recalled neutral and emotional experiences from their past were impaired in their memory for the neutral (but not for the emotional) experiences one week later. The effect of learning the story depended critically on the preceding reactivation of the autobiographical memories since learning without reactivation had no effect. These results suggest that new learning impedes the reconsolidation of neutral autobiographical memories.

Differential Neural Activity during Search of Specific and General Autobiographical Memories elicited by Musical Cues

Ford, Jaclyn Hennessey; Addis, Donna Rose; Giovanello, Kelly S.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
47.14%
Previous neuroimaging studies that have examined autobiographical memory specificity have utilized retrieval cues associated with prior searches of the event, potentially changing the retrieval processes being investigated. In the current study, musical cues were used to naturally elicit memories from multiple levels of specificity (i.e., lifetime period, general event, and event-specific). Sixteen young adults participated in a neuroimaging study in which they retrieved autobiographical memories associated with musical cues. These musical cues led to the retrieval of highly emotional memories that had low levels of prior retrieval. Retrieval of all autobiographical memory levels was associated with activity in regions in the autobiographical memory network, specifically the ventromedial prefrontal cortex, posterior cingulate, and right medial temporal lobe. Owing to the use of music, memories from varying levels of specificity were retrieved, allowing for comparison of event memory and abstract personal knowledge, as well as comparison of specific and general event memory. Dorsolateral and dorsomedial prefrontal regions were engaged during event retrieval relative to personal knowledge retrieval, and retrieval of specific event memories was associated with increased activity in the bilateral medial temporal lobe and dorsomedial prefrontal cortex relative to retrieval of general event memories. These results suggest that the initial search processes for memories of different specificity levels preferentially engage different components of the autobiographical memory network. The potential underlying causes of these neural differences are discussed.

Are Autobiographical Memories Inherently Social? Evidence from an fMRI Study

Wilbers, Linda; Deuker, Lorena; Fell, Juergen; Axmacher, Nikolai
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
Publicado em 21/09/2012 EN
Relevância na Pesquisa
47.19%
The story of our lifetime – our narrative self – is constructed from our autobiographical memories. A central claim of social psychology is that this narrative self is inherently social: When we construct our lives, we do so in a real or imagined interaction. This predicts that self-referential processes which are involved in recall of autobiographical memories overlap with processes involved in social interactions. Indeed, previous functional MRI studies indicate that regions in the medial prefrontal cortex (mPFC) are activated during autobiographical memory recall and virtual communication. However, no fMRI study has investigated recall of autobiographical memories in a real-life interaction. We developed a novel paradigm in which participants overtly reported self-related and other-related memories to an experimenter, whose non-verbal reactions were being filmed and online displayed to the participants in the scanner. We found that recall of autobiographical vs. non-autobiographical memories was associated with activation of the mPFC, as was recall in the social as compared to a non-social control condition; however, both contrasts involved different non-overlapping regions within the mPFC. These results indicate that self-referential processes involved in autobiographical memory recall are different from processes supporting social interactions...

Detecting representations of recent and remote autobiographical memories in vmPFC and hippocampus

Bonnici, Heidi M.; Chadwick, Martin J.; Lutti, Antoine; Hassabis, Demis; Weiskopf, Nikolaus; Maguire, Eleanor A.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em 21/11/2012 EN
Relevância na Pesquisa
47.2%
How autobiographical memories are represented in the human brain and whether this changes with time are questions central to memory neuroscience. Two regions in particular have been consistently implicated, the ventromedial prefrontal cortex (vmPFC) and the hippocampus, although their precise contributions are still contested. The key question in this debate, when reduced to its simplest form, concerns where information about specific autobiographical memories is located. Here we availed ourselves of the opportunity afforded by multi-voxel pattern analysis (MVPA) to provide an alternative to conventional neuropsychological and fMRI approaches, by detecting representations of individual autobiographical memories in patterns of fMRI activity. We examined whether information about specific recent (two weeks old) and remote (ten years old) autobiographical memories was represented in vmPFC and hippocampus, and other medial temporal and neocortical regions. vmPFC contained information about recent and remote autobiographical memories, although remote memories were more readily detected there, indicating that consolidation or a change of some kind had occurred. Information about both types of memory was also present in the hippocampus, suggesting it plays a role in the retrieval of vivid autobiographical memories regardless of remoteness. Interestingly...

The Episodicity of Verbal Reports of Personally Significant Autobiographical Memories: Vividness Correlates with Narrative Text Quality More than with Detailedness or Memory Specificity

Habermas, Tilmann; Diel, Verena
Fonte: Frontiers Media S.A. Publicador: Frontiers Media S.A.
Tipo: Artigo de Revista Científica
Publicado em 19/08/2013 EN
Relevância na Pesquisa
46.95%
How can we tell from a memory report whether a memory is episodic or not? Vividness is required by many definitions, whereas detailedness, memory specificity, and narrative text type are competing definitions of episodicity used in research. We explored their correlations with vividness in personally significant autobiographical memories to provide evidence to support their relative claim to define episodic memories. In addition, we explored differences between different memory types and text types as well as between memories with different valences. We asked a lifespan sample (N = 168) of 8-, 12-, 16-, 20-, 40-, and 65-year-olds of both genders (N = 27, 29, 27, 27, 28, 30) to provide brief oral life narratives. These were segmented into thematic memory units. Detailedness of person, place, and time did not correlate with each other or either vividness, memory specificity, or narrative text type. Narrative text type, in contrast, correlated both with vividness and memory specificity, suggesting narrative text type as a good criterion of episodicity. Emotionality turned out to be an even better predictor of vividness. Also, differences between narrative, chronicle, and argument text types and between specific versus more extended and atemporal memories were explored as well as differences between positive...

Dysphoric students show higher use of the observer perspective in their retrieval of positive versus negative autobiographical memories

Nelis, Sabine; Debeer, Elise; Holmes, Emily A.; Raes, Filip
Fonte: Taylor & Francis Publicador: Taylor & Francis
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
47.01%
Autobiographical memories are retrieved as images from either a field perspective or an observer perspective. The observer perspective is thought to dull emotion. Positive affect is blunted in depressed mood. Consequently, are positive events recalled from an observer perspective in depressed mood? We investigated the relationship between memory vantage perspective and depressive symptoms in a student sample. Participants completed the Autobiographical Memory Test (AMT; Williams & Broadbent, 1986) and assessed the perspective accompanying each memory. The Beck Depression Inventory-II (BDI-II; Beck, Steer, & Brown, 1996) and the Responses to Positive Affect questionnaire (RPA; Feldman, Joormann, & Johnson, 2008) were administered. The results showed a small positive association between depressive symptoms and the use of an observer perspective for positive autobiographical memories, but not for negative memories. Furthermore, comparing a subgroup with clinically significant symptom levels (dysphoric students) with non-dysphoric individuals revealed that dysphoric students used an observer perspective more for positive memories compared with negative memories. This was not the case for non-dysphoric students. The observer perspective in dysphorics was associated with a dampening cognitive style in response to positive experiences.

Retrieval of Recent Autobiographical Memories is Associated with Slow-Wave Sleep in Early AD

Rauchs, Géraldine; Piolino, Pascale; Bertran, Françoise; de La Sayette, Vincent; Viader, Fausto; Eustache, Francis; Desgranges, Béatrice
Fonte: Frontiers Media S.A. Publicador: Frontiers Media S.A.
Tipo: Artigo de Revista Científica
Publicado em 18/09/2013 EN
Relevância na Pesquisa
47.08%
Autobiographical memory is commonly impaired in Alzheimer’s disease (AD). However, little is known about the very recent past which is though highly important in daily life adaptation. In addition, the impact of sleep disturbances, also frequently reported in AD, on the consolidation, and retrieval of autobiographical memories remains to be assessed. Using an adaptation of the TEMPau task, we investigated the neural substrates of autobiographical memory for recent events and the potential relationship with sleep in 14 patients with mild AD. On day 1, autobiographical memory was explored across three periods: remote (18–30 years), the last 2 years and the last month. After testing, sleep was recorded using polysomnography. The next day, AD patients benefited a resting-state 18FDG-PET scan and a second exploration of autobiographical memory, focusing on the very recent past (today and yesterday). Total recall and episodic recall scores were obtained. In addition, for all events recalled, Remember responses justified by specific factual, spatial, and temporal details were measured using the Remember/Know paradigm. Retrieval of autobiographical memories was impaired in AD, but recall of young adulthood and very recent events was relatively better compared to the two intermediate periods. Recall of recent events (experienced the day and the day preceding the assessment) was correlated with brain glucose consumption in the precuneus and retrosplenial cortex...

Differential Effects of Arousal in Positive and Negative Autobiographical Memories

Ford, Jaclyn Hennessey; Addis, Donna Rose; Giovanello, Kelly S.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
46.99%
Autobiographical memories are characterized by a range of emotions and emotional reactions. Recent research has demonstrated that differences in emotional valence (positive v. negative emotion) and arousal (the degree of emotional intensity) differentially influence the retrieved memory narrative. Although the mnemonic effects of valence and arousal have both been heavily studied, it is currently unclear whether the effects of emotional arousal are equivalent for positive and negative autobiographical events. In the current study, multilevel models were used to examine differential effects emotional valence and arousal on the richness of autobiographical memory retrieval both between and within subjects. Thirty-four young adults were asked to retrieve personal autobiographical memories associated with popular musical cues and to rate the valence, arousal, and richness of these events. The multilevel analyses identified independent influences of valence and intensity upon retrieval characteristics at the within and between subject levels. In addition, the within subject interactions between valence and arousal highlighted differential effects of arousal for positive and negative memories. These findings have important implications for future studies of emotion and memory...

Suppression-Induced Reduction in the Specificity of Autobiographical Memories

Stephens, Elizabeth; Braid, Amy; Hertel, Paula T.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /04/2013 EN
Relevância na Pesquisa
46.97%
To extend its relevance to everyday forgetting, we applied the think/no-think (TNT) suppression method devised by Anderson and Green (2001) to autobiographical memories. Dysphoric and nondysphoric participants first generated autobiographical memories and corresponding titles to neutral and emotionally positive or negative cues. During the TNT phase, participants repeatedly practiced responding to some cues with their associated titles and avoiding thoughts about titles and memories associated with other cues. Later, they were asked to report memories associated with all cues, including baseline cues not presented during the TNT phase. Results revealed impaired recall, as measured by reductions in specificity, for suppressed memories relative to baseline memories. Also, regardless of TNT instructions, memories of dysphoric students who had received negative cues became less specific and less negative than they were at the outset.

Representations of recent and remote autobiographical memories in hippocampal subfields

Bonnici, Heidi M; Chadwick, Martin J; Maguire, Eleanor A
Fonte: BlackWell Publishing Ltd Publicador: BlackWell Publishing Ltd
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
47.06%
The hippocampus has long been implicated in supporting autobiographical memories, but little is known about how they are instantiated in hippocampal subfields. Using high-resolution functional magnetic resonance imaging (fMRI) combined with multivoxel pattern analysis we found that it was possible to detect representations of specific autobiographical memories in individual hippocampal subfields. Moreover, while subfields in the anterior hippocampus contained information about both recent (2 weeks old) and remote (10 years old) autobiographical memories, posterior CA3 and DG only contained information about the remote memories. Thus, the hippocampal subfields are differentially involved in the representation of recent and remote autobiographical memories during vivid recall. © 2013 The Authors. Hippocampus Published by Wiley Periodicals, Inc.

Life review with older women: an intervention to reduce depression and improve autobiographical memory

Gonçalves, Daniela C.; Albuquerque, Pedro Barbas; Paúl, Constança
Fonte: Editrice Kurtis Publicador: Editrice Kurtis
Tipo: Artigo de Revista Científica
Publicado em //2009 ENG
Relevância na Pesquisa
46.96%
Background and aims: As life expectancy rises worldwide and the population grows older, psychopathology in older adults becomes a significant public health concern and intervention methods acquire renewed importance. The aim of the present study was to assess the efficacy of Life Review as an intervention strategy in working with older women with depressive symptoms, specifically through promotion of the specificity of autobiographical memories. Methods: Twenty-two participants were randomly assigned to experimental or control conditions. Intervention consisted of four individual sessions of Life Review, structured along 14 questions aimed at prompting autobiographical memory specificity. Participants in the control condition did not receive intervention. Results: Results indicated a significant change in the experimental group, appearing as the reduction of depressive symptoms (t(20)=3.58, p<0.05) and an increase in life satisfaction (t(20)=-3.83, p<0.05), as well as a significant increase in the specificity (t(20)=-3.46, p<0.05) and positivity (t(20)=-4.23, p<0.05) of autobiographical memories. All variables reached high effect sizes, with an effect size of r=0.64 regarding depressive symptoms. Conclusions: Results suggest that Life Review is a valuable tool for use with older adults...

The Neural Architecture of Music-Evoked Autobiographical Memories

Janata, Petr
Fonte: Oxford University Press Publicador: Oxford University Press
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
47.1%
The medial prefrontal cortex (MPFC) is regarded as a region of the brain that supports self-referential processes, including the integration of sensory information with self-knowledge and the retrieval of autobiographical information. I used functional magnetic resonance imaging and a novel procedure for eliciting autobiographical memories with excerpts of popular music dating to one's extended childhood to test the hypothesis that music and autobiographical memories are integrated in the MPFC. Dorsal regions of the MPFC (Brodmann area 8/9) were shown to respond parametrically to the degree of autobiographical salience experienced over the course of individual 30 s excerpts. Moreover, the dorsal MPFC also responded on a second, faster timescale corresponding to the signature movements of the musical excerpts through tonal space. These results suggest that the dorsal MPFC associates music and memories when we experience emotionally salient episodic memories that are triggered by familiar songs from our personal past. MPFC acted in concert with lateral prefrontal and posterior cortices both in terms of tonality tracking and overall responsiveness to familiar and autobiographically salient songs. These findings extend the results of previous autobiographical memory research by demonstrating the spontaneous activation of an autobiographical memory network in a naturalistic task with low retrieval demands.

Age-related alterations of brain network underlying the retrieval of emotional autobiographical memories: an fMRI study using independent component analysis

Ge, Ruiyang; Fu, Yan; Wang, Dahua; Yao, Li; Long, Zhiying
Fonte: Frontiers Media S.A. Publicador: Frontiers Media S.A.
Tipo: Artigo de Revista Científica
Publicado em 14/08/2014 EN
Relevância na Pesquisa
46.93%
Normal aging has been shown to modulate the neural underpinnings of autobiographical memory and emotion processing. Moreover, previous researches have suggested that aging produces a “positivity effect” in autobiographical memory. Although a few imaging studies have investigated the neural mechanism of the positivity effect, the neural substrates underlying the positivity effect in emotional autobiographical memory is unclear. To understand the age-related neural changes in emotional autobiographical memory that underlie the positivity effect, the present functional magnetic resonance imaging (fMRI) study used the independent component analysis (ICA) method to compare brain networks in younger and older adults as they retrieved positive and negative autobiographical events. Compared to their younger counterparts, older adults reported relatively higher positive feelings when retrieving emotional autobiographical events. Imaging data indicated an age-related reversal within the ventromedial prefrontal/anterior cingulate cortex (VMPFC/ACC) and the left amygdala of the brain networks that were engaged in the retrieval of autobiographical events with different valence. The retrieval of negative events compared to positive events induced stronger activity in the VMPFC/ACC and weaker activity in the amygdala for the older adults...

Different Temporal Patterns of Specific and General Autobiographical Memories across the Lifespan in Alzheimer's Disease

Philippi, Nathalie; Rousseau, François; Noblet, Vincent; Botzung, Anne; Després, Olivier; Cretin, Benjamin; Kremer, Stéphane; Blanc, Frédéric; Manning, Liliann
Fonte: Hindawi Publishing Corporation Publicador: Hindawi Publishing Corporation
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
46.88%
We compared specific (i.e., associated with a unique time and space) and general (i.e., extended or repeated events) autobiographical memories (AbM) in Alzheimer's disease (AD). The comparison aims at investigating the relationship between these two components of AbM across the lifespan and the volume of cerebral regions of interest within the temporal lobe. We hypothesized that the ability to elicit specific memories would correlate with hippocampal volume, whereas evoking general memories would be related to lateral temporal lobe. AbM was assessed using the modified Crovitz test in 18 patients with early AD and 18 matched controls. The proportions of total memories—supposed to reflect the ability to produce general memories—and specific memories retrieved were compared between AD patients and controls. Correlations to MRI volumes of temporal cortex were tested. We found different temporal patterns for specific and general memories in AD patients, with (i) relatively spared general memories, according to a temporal gradient that preserved remote memories, predominantly associated with right lateral temporal cortex volume. (ii) Conversely, the retrieval of specific AbMs was impaired for all life periods and correlated with bilateral hippocampal volumes. Our results highlight a shift from an initially episodic to a semantic nature of AbMs during AD...

Brain structural, functional, and cognitive correlates of recent versus remote autobiographical memories in amnestic Mild Cognitive Impairment

Tomadesso, Clémence; Perrotin, Audrey; Mutlu, Justine; Mézenge, Florence; Landeau, Brigitte; Egret, Stéphanie; de la Sayette, Vincent; Jonin, Pierre-Yves; Eustache, Francis; Desgranges, Béatrice; Chételat, Gaël
Fonte: Elsevier Publicador: Elsevier
Tipo: Artigo de Revista Científica
Publicado em 28/05/2015 EN
Relevância na Pesquisa
47.1%
Deficits in autobiographical memory appear earlier for recent than for remote life periods over the course of Alzheimer's disease (AD). The present study aims to further our understanding of this graded effect by investigating the cognitive and neural substrates of recent versus remote autobiographical memories in patients with amnestic Mild Cognitive Impairment (aMCI) thanks to an autobiographical fluency task. 20 aMCI patients and 25 Healthy elderly Controls (HC) underwent neuropsychological tests assessing remote (20-to-30 years old) and recent (the ten last years) autobiographical memory as well as episodic and semantic memory, executive function and global cognition. All patients also had a structural MRI and an FDG-PET scan. Correlations were assessed between each autobiographical memory score and the other tests as well as grey matter volume and metabolism. Within the aMCI, performances for the remote period correlated with personal semantic memory and episodic memory retrieval whereas performances for the recent period only correlated with episodic memory retrieval. Neuroimaging analyses revealed significant correlations between performances for the remote period and temporal pole and temporo-parietal cortex volumes and anterior cingulate gyrus metabolism...

Relação entre ansiedade, vinculação e relações interpessoais na evocação de memórias autobiográficas : A influência da ansiedade na evocação de memórias autobiográficas

Neto, Joana da Luz
Fonte: Instituto Universitário de Ciências Psicológicas, Sociais e da Vida Publicador: Instituto Universitário de Ciências Psicológicas, Sociais e da Vida
Tipo: Dissertação de Mestrado
Publicado em //2015 POR
Relevância na Pesquisa
47.19%
Dissertação de Mestrado apresentada ao ISPA - Instituto Universitário; A área das memórias autobiográficas, associada à ansiedade, é recente na literatura científica. O objetivo desta investigação foi estudar a influência dos níveis de ansiedade na evocação de memórias autobiográficas. A amostra foi constituída por 60 participantes com ausência de patologia (38 do género feminino e 22 do género masculino), em que a sua maioria eram estudantes universitários. Os participantes preencheram o Inventário de Depressão de Beck, o Inventário de Estado-Traço de Ansiedade, a Escala de Vinculação do Adulto, o Inventário de Problemas Interpessoais e realizaram a Tarefa de Memórias Autobiográficas. Observou-se que quando a ansiedade traço aumenta, são evocadas menos memórias autobiográficas de valência emocional positiva e menos memórias autobiográficas de estrutura categórica. Numa análise mais fina, verificou-se um aumento na evocação de memórias autobiográficas de estrutura alargadas nos participantes do género masculino com o aumento da ansiedade estado e ansiedade traço. Em geral, independentemente dos níveis de ansiedade, a amostra evocou mais memórias autobiográficas de valência emocional negativa.; ABSTRACT: The area of autobiographical memories...