Página 1 dos resultados de 2955 itens digitais encontrados em 0.018 segundos

Hydration and N-acetylcysteine in acute renal failure caused by iodinated contrast medium: an experiment with rats

PINTO, Carolina F.; WATANABE, Mirian; VATTIMO, Maria de Fatima F.
Fonte: WICHTIG EDITORE Publicador: WICHTIG EDITORE
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
96.15%
Background: The involvement of nephrotoxic agents in acute renal failure (ARF) has increased over the last few decades. Among the drugs associated with nephrotoxic ARF are the radiologic contrast media whose nephrotoxic effects have grown, following the increasing diagnostic use of these agents. Methods: We evaluated the effect of iodinated contrast (IC) medium, administered in combination, or not, with hyperhydration or N-acetylcysteine (NAC), on creatinine clearance, production of urinary peroxides and renal histology of rats. Adult Wistar rats treated for 5 days were divided into the following groups: control (saline, 3 ml/kg/day, intraperitoneally [i.p.]), IC (sodium iothalamate meglumine, 3 ml/kg/day i.p.), IC + water (12 mL water, orally + IC, 3 ml/kg/day i.p. after 1 hour), IC + NAC (NAC, 150 mg/kg/day, orally + IC, 3 ml/kg/day i.p. after 1 hour) and IC + water + NAC. Results: IC medium reduced renal function, with maintenance of urinary flow. Hyperhydration did not reduce the nephrotoxic effect of the IC agent, which was observed in the group IC + NAC. The combination of hyperhydration and NAC had no superior protective effect compared with NAC alone. An increase in urinary peroxides was observed in the IC group, with NAC or water or the combination of both reducing this parameter. Histopathologic analysis revealed no significant alterations. Conclusions: In summary...

Papel da heme-oxigenase na proteção pelas estatinas na insuficiência renal aguda isquêmica em ratos.; Role os heme-oxygenase in the protection of statin in ischemic acute renal failure in rats.

Shibuya, Claudia Akemi
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 31/07/2006 PT
Relevância na Pesquisa
96.14%
O inibidor de HMG redutase (estatina) pode ter papel protetor na função renal por estimulação da atividade de HO-1. Este estudo foi desenvolvido para avaliar se a associação desses dois agentes poderia induzir um efeito mais pronunciado sobre a função renal (FR) após insuficiência renal aguda isquêmica. A isquemia foi obtida por meio do clampeamento dos pedículos renais bilaterais por 30 minutos, seguida de reperfusão. Foram utilizados ratos wistar, machos, pesando entre 250-300g, distribuídos nos grupos: SHAM (controle, sem clampeamento renal); Isquemia; Estatina (animais que receberam 0,5 mg/kg, via oral, v.o., por 3 dias); Iquemia+Estatina; Hemin (indutor de HO-1, 1 mg/100g, i.p., 24h antes da cirurgia); Isquemia+Hemin; SnPP (inibidor de HO-1, 2µmol/kg i.p. 24h antes da cirurgia); Isquemia+SnPP; Estatina+Hemin; Isquemia+Estatina+Hemin; Estatina+SnPP; Isquemia+Estatina+SnPP. Foram avaliados a função renal (FR) (clearance de creatinina, método Jaffé), a excreção de peróxidos urinário (FOX-2), a osmolalidade urinária (osmômetro) e a imunohistoquímica para ED-1. Os resultados mostraram que a estatina otimizou a FR e reduziu a excreção de peróxidos urinários. A indução da HO-1 apresentou padrão similar ao descrito para estatina. A associação de estatina+Hemin induziu melhora de FR...

High volume peritoneal dialysis for acute renal failure

Gabriel, Daniela Ponce; Ribeiro do Nascimento, Ginivaldo Victor; Caramori, Jacqueline Teixeira; Martim, Luis Cuadrado; Barretti, Pasqual; Balbi, Andre Luis
Fonte: Multimed Inc Publicador: Multimed Inc
Tipo: Artigo de Revista Científica Formato: 277-282
ENG
Relevância na Pesquisa
96.08%
Background. Peritoneal dialysis (PD) is still widely used for acute renal failure (ARF) in developing countries despite concerns about its inadequacy. Continuous PD has been evaluated in ARF by analyzing the resolution of metabolic abnormality and normalization of plasma pH, bicarbonate, and potassium.Methodology: A prospective study was performed on 30 ARF patients who were assigned to high-dose continuous PD (Kt/V = 0.65 per session) via a flexible catheter (Tenckhoff) and automated PD with a cycler. Fluid removal, pH and metabolic control, protein Loss, and patient outcome were evaluated.Results: Patients received 236 continuous PD sessions; 76% were admitted to ICUs. APACHE II score was 32.2 +/- 8.65. BUN concentrations stabilized after 3 sessions, creatinine after 4, and bicarbonate and pH after 2. Fluid removal was 2.1 +/- 0.62 L/day. Creatinine and urea clearances were 15.8 +/- 4.16 and 17.3 +/- 5.01 mL/minute respectively. Normalized creatinine clearance and urea Kt/V values were 110.6 +/- 22.5 L/week/1.73 m(2) body surface area and 3.8 +/- 0.6 respectively. Solute reduction index was 41% +/- 6.5% per session. Serum albumin values remained stable in spite of considerable protein tosses (median 21.7 g/day, interquartile range 9.1 - 29.8 g/day). Regarding ARF outcome...

Acute renal failure: Clinical outcome and causes of death

Barretti, Pasqual; Soares, Vitor Augusto
Fonte: Marcel Dekker Inc Publicador: Marcel Dekker Inc
Tipo: Artigo de Revista Científica Formato: 253-257
ENG
Relevância na Pesquisa
96.25%
Acute renal failure (ARF) is a frequent complication in hospitalized patients and is strongly related to increase in mortality. In order to analyze the clinical outcome and the prognostic factors in hospital-acquired ARF a prospective study was performed. Data from 200 patients with established ARF during the period of January 1987 through July 1990 were collected. The incidence of ARF was 4.9/1000 admissions. Renal ischemia (50%) and nephrotoxic drugs (21%) were the main etiologic factors. The histologic study done in 43 patients showed: acute tubular necrosis (53%), tubular hydropic degeneration (16%), glomerulopathies (16%), and other lesions (15%). Dialysis therapy was performed in 101 patients. The mortality rate was 46.5% and the most important causes of death were. sepsis (38%), respiratory failure (19%), and multiple organ failure (11%). Higher mortality was observed in oliguric patients (62.9%) than nonoliguric (34.5%) (p < 0.05) and in ischemic renal failure (56.7%) when compared to nephrotoxic renal failure (14.7%) (p < 0.05). As primary cause of death was not associated to the acute renal failure, conclude that acute renal failure is an important marker of the gravity of the underlying disease and not the cause of death.

Peritoneal dialysis in acute renal failure

Gabriel, Daniela Ponce; Nascimento, Ginivaldo Victor R.; Caramori, Jacqueline Teixeira; Martim, Luís Cuadrado; Barretti, Pasqual; Balbi, André Luís
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Revisão Formato: 451-456
ENG
Relevância na Pesquisa
96.13%
The definition of adequate dialysis in acute renal failure (ARF) is complex and involves the time of referral to dialysis, dose, and dialytic method. Nephrologist experience with a specific procedure and the availability of different dialysis modalities play an important role in these choices. There is no consensus in literature on the best method or ideal dialysis dose in ARF. Peritoneal dialysis (PD) is used less and less in ARF patients, and is being replaced by continuous venovenous therapies. However, it should not be discarded as a worthless therapeutic option for ARF patients. PD offers several advantages over hemodialysis, such as its technical simplicity, excellent cardiovascular tolerance, absence of an extracorporeal circuit, lack of bleeding risk, and low risk of hydro-electrolyte imbalance. PD also has some limitations, though: it needs an intact peritoneal cavity, carries risks of peritoneal infection and protein losses, and has an overall lower effectiveness. Because daily solute clearance is lower with PD than with daily HD, there have been concerns that PD cannot control uremia in ARF patients. Controversies exist concerning its use in patients with severe hypercatabolism; in these cases, daily hemodialysis or continuous venovenous therapy have been preferred. There is little literature on PD in ARF patients...

Participação de mastocitos na lesão renal induzida por isquemia/reperfusão; Role of mast cells in ischemic acute renal failure

Felipe Caetano Beraldo
Fonte: Biblioteca Digital da Unicamp Publicador: Biblioteca Digital da Unicamp
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 30/08/2007 PT
Relevância na Pesquisa
96.22%
A lesão renal causada pela isquemia é a principal causa de insuficiência renal aguda [IRA] em rins nativos e transplantados. A fisiopatologia da IRA induzida por isquemia/reperfusão [I/R] envolve alterações na hemodinâmica renal, lesão de células endoteliais e tubulares e os processos inflamatórios, que resultam na ativação e lesão de células endoteliais, aumento da adesão entre células endoteliais e leucócitos, migração de leucócitos para o tecido afetado e comprometimento microvascular. Dentre as células inflamatórias envolvidas no modelo I/R, estudos demonstram a participação de macrófagos e leucócitos. Os mastócitos, apesar de participarem ativamente do processo de fibrose intersticial renal, são pouco estudados neste modelo. Estudos anteriores demonstraram que a presença de mastócitos em transplantes renais humanos com necrose tubular aguda [NTA] apresentou correlação com o desenvolvimento de fibrose intersticial. Assim, o presente estudo tem como hipótese que a presença de mastócitos no modelo de I/R seria um fator de risco para o desenvolvimento de nefropatia crônica. Para tanto, animais [ratos Wistar machos] foram submetidos ao procedimento clássico de isquemia/reperfusão e sacrificados a períodos variáveis de 0 a 14 dias. Ao final de cada período foram analisadas a função renal [creatinina sérica]...

Técnicas Dialíticas na Insuficiência Renal Aguda; Dialysis Therapy in Acute Renal Failure

Rocha, S.; Aguilar, A.; Mota, C.; Faria, M. S.; Costa, T.; Carvalho, C.; Marcelino, F.; Mota, C.; Rocha, P.; Pereira, E.; Duarte, C.
Fonte: Centro Hospitalar do Porto Publicador: Centro Hospitalar do Porto
Tipo: Artigo de Revista Científica
Publicado em //2006 POR
Relevância na Pesquisa
96.12%
RESUMO A insuficiência renal aguda (IRA) é uma situação rara em idade pediátrica, podendo surgir aliada a variadas condições clínicas. Quando as medidas de suporte não são suficientes para o controlo da IRA, torna-se necessário o início de terapêutica de substituição da função renal. Objectivo: Analisar as indicações e complicações dos diferentes métodos de diálise aguda nos doentes internados na Unidade de Cuidados Intensivos e/ou no Serviço de Nefrologia Pediátrica do Hospital Maria Pia. Doentes e métodos: Foi efectuado um estudo retrospectivo dos doentes com IRA que necessitaram de tratamento substitutivo da função renal entre Janeiro de 1990 e Dezembro de 2004. Analisaram-se aspectos clínicos e laboratoriais, indicações e complicações do procedimento dialítico e evolução dos doentes. Foi analisado também, o número anual de doentes tratados com diálise aguda no Hospital. Resultados. O estudo incluiu 29 crianças com idades comprendidas entre 1 e 15 anos, dos quais onze (37,9%) tinham menos de 12 meses de idade (6 recém nascidos). A sépsis foi a condição subjacente à IRA em 11 (37,9%) doentes, sendo predominante no grupo de recém nascidos. O síndrome hemolítico urémico foi a etiologia de IRA em 10 (34...

Hemorrhagic syndrome and Acute renal failure in a pregnant woman after contact with Lonomia caterpillars: a case report

FAN,Hui Wen; CARDOSO,João Luiz C.; OLMOS,Rodrigo Díaz; ALMEIDA,Flávia Jacqueline; VIANA,Rosana Porto; MARTINEZ,Ana Paula Pinto
Fonte: Instituto de Medicina Tropical Publicador: Instituto de Medicina Tropical
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/03/1998 EN
Relevância na Pesquisa
96.11%
A case of a 37-week pregnant woman who developed a hemorrhagic syndrome and acute renal failure after contact with Lonomia caterpillars is reported. The accident also initiated labour and the patient gave birth to an alive child. Some pathophysiological aspects of the genital bleeding and of the acute renal failure are discussed.

Acute renal failure after massive honeybee stings

Daher,Elizabeth De Francesco; Silva Junior,Geraldo Bezerra da; Bezerra,Glaydcianne Pinheiro; Pontes,Lícia Borges; Martins,Alice Maria Costa; Guimarães,José Ambrósio
Fonte: Instituto de Medicina Tropical Publicador: Instituto de Medicina Tropical
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2003 EN
Relevância na Pesquisa
96.18%
Two clinical cases of patients who survived after numerous attacks of Africanized bees (600 and 1500 bee stings, respectively) are reported. Clinical manifestation was characterized by diffuse and widespread edema, a burning sensation in the skin, headache, weakness, dizziness, generalized paresthesia, somnolence and hypotension. Acute renal failure developed and was attributed to hypotension, intravascular hemolysis, myoglobinuria due to rhabdomyolysis and probably to direct toxic effect of the massive quantity of injected venom. They were treated with antihistaminic, corticosteroids and fluid infusion. One of them had severe acute renal failure and dialysis was required. No clinical complication was observed during hospital stay and complete renal function recovery was observed in both patients. In conclusion, acute renal failure after bee stings is probably due to pigment nephropathy associated with hypovolemia. Early recognition of this syndrome is crucial to the successful management of these patients.

Contribution of CD4+ T cells to the early mechanisms of ischemia- reperfusion injury in a mouse model of acute renal failure

Pinheiro,H.S.; Camara,N.O.S.; Noronha,I.L.; Maugeri,I.L.; Franco,M.F.; Medina,J.O.A.P.; Pacheco-Silva,A.
Fonte: Associação Brasileira de Divulgação Científica Publicador: Associação Brasileira de Divulgação Científica
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/04/2007 EN
Relevância na Pesquisa
96.13%
Renal ischemia-reperfusion (IR) injury is the major cause of acute renal failure in native and transplanted kidneys. Mononuclear leukocytes have been reported in renal tissue as part of the innate and adaptive responses triggered by IR. We investigated the participation of CD4+ T lymphocytes in the pathogenesis of renal IR injury. Male mice (C57BL/6, 8 to 12 weeks old) were submitted to 45 min of ischemia by renal pedicle clamping followed by reperfusion. We evaluated the role of CD4+ T cells using a monoclonal depleting antibody against CD4 (GK1.5, 50 µ, ip), and class II-major histocompatibility complex molecule knockout mice. Both CD4-depleted groups showed a marked improvement in renal function compared to the ischemic group, despite the fact that GK1.5 mAb treatment promoted a profound CD4 depletion (to less than 5% compared to normal controls) only within the first 24 h after IR. CD4-depleted groups presented a significant improvement in 5-day survival (84 vs 80 vs 39%; antibody treated, knockout mice and non-depleted groups, respectively) and also a significant reduction in the tubular necrosis area with an early tubular regeneration pattern. The peak of CD4-positive cell infiltration occurred on day 2, coinciding with the high expression of ßC mRNA and increased urea levels. CD4 depletion did not alter the CD11b infiltrate or the IFN-g and granzyme-B mRNA expression in renal tissue. These data indicate that a CD4+ subset of T lymphocytes may be implicated as key mediators of very early inflammatory responses after renal IR injury and that targeting CD4+ T lymphocytes may yield novel therapies.

Collagen XVIII/endostatin expression in experimental endotoxemic acute renal failure

Cichy,M.C.; Rocha,F.G.G.; Tristão,V.R.; Pessoa,E.A.; Cenedeze,M.A.; Nürmberg Junior,R.; Schor,N.; Bellini,M.H.
Fonte: Associação Brasileira de Divulgação Científica Publicador: Associação Brasileira de Divulgação Científica
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2009 EN
Relevância na Pesquisa
96.09%
Acute renal failure (ARF) is a frequent complication of Gram-negative sepsis, with a high risk of mortality. Lipopolysaccharide (LPS)-induced ARF is associated with hemodynamic changes that are strongly influenced by the overproduction of nitric oxide (NO) through the cytokine-mediated up-regulation of inducible NO synthase. LPS-induced reductions in systemic vascular resistance paradoxically culminate in renal vasoconstriction. Collagen XVIII is an important component of the extracellular matrix expressed in basement membranes. Its degradation by matrix metalloproteases, cathepsins and elastases results in the formation of endostatin, claimed to have antiangiogenic activity and to be a prominent vasorelaxing agent. We evaluated the expression of endostatin/collagen XVIII in an endotoxemic ARF model. ARF was induced in C57BL/6 mice by intraperitoneal injection of LPS (10 mg/kg) followed by sacrifice 4 and 12 h later. Kidney tissue was the source of RNA and protein and the subject of histological analysis. As early as 4 h after LPS administration, blood urea, creatinine and NO levels were significantly increased compared to control. Endostatin/collagen XVIII mRNA levels were 0.71 times lower than sham-inoculated mice 4 h after LPS inoculation...

Acute pancreatitis and acute renal failure following multiple hornet stings

Sharma,N.; Balamurugeshan,P. K.; Sharma,A.
Fonte: Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP Publicador: Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/04/2006 EN
Relevância na Pesquisa
96.14%
Hymenoptera is a class of insects that sting in order to subdue their prey. Humans coming into accidental contact with these insects results in stings that may cause from mild local reaction like weal formation around the sting site to severe systemic reactions such as intravascular hemolysis, acute renal failure, pulmonary edema, cerebral edema, and rarely pancreatitis. We report here the clinical course of a patient who developed concurrent acute pancreatitis and pigment-induced acute renal failure after multiple hornet stings.

Renal Biopsy Findings in Acute Renal Failure in the Cohort of Patients in the Spanish Registry of Glomerulonephritis

López-Gómez, Juan M.; Rivera, Francisco;
Fonte: American Society of Nephrology Publicador: American Society of Nephrology
Tipo: Artigo de Revista Científica
Publicado em /05/2008 EN
Relevância na Pesquisa
96.16%
Background and objectives: Renal biopsy in acute renal failure of unknown origin provides irreplaceable information for diagnosis, treatment, and prognosis. This study analyzed the frequency and clinicopathologic correlations of renal native biopsied acute renal failure in Spain during the period 1994 through 2006.

Prävention der Kontrastmittelnephrophatie durch Ubiquinon (Coenzym Q10) bzw. durch die Kombination Ubiquinon/ Theophyllin bei Patienten mit eingeschränkter Nierenfunktion und Volumenüberladung; Prevention of Contrast Media Induced Acute Renal Failure in Patients with Impaired Renal Function by Ubiquinon (Coenzyme Q10) resp. the Combination of Ubiquinon and Theophylline

Teuber, Sven Alexander
Fonte: Universidade de Tubinga Publicador: Universidade de Tubinga
Tipo: Dissertação
DE_DE
Relevância na Pesquisa
96.26%
In verschiedenen Studien konnte gezeigt werden, dass die Hydratation eine Möglichkeit zur Prävention der Kontrastmittelnephropathie (KMN) bei Patienten mit bereits eingeschränkter Nierenfunktion darstellt. Doch bisher konnte sich leider noch keine Strategie zur Vermeidung von kontrastmittelinduzierten Nierenschäden bei Patienten durchsetzen, bei denen eine ausreichende Prähydratation aufgrund von Volumenüberladung (Herzinsuffizienz, nephrotisches Syndrom etc.) nicht möglich ist. Der Adenosinantagonist Theophyllin und das Antioxidanz Ubiquinon (Q10) zeigen bei dieser Fragestellung vielleicht einen Weg auf. Im Rahmen des Studienprotokolls wurden 30 Patienten (68,37 + 9,550 Jahre; 5w/ 25m) mit einem mittleren Serumkreatinin von 1,697+ 0,4327 mg/dl und einer Volumenüberladung verursacht durch u.a. eine Herzinsuffizienz, die eine Kontrastmitteluntersuchung mit mindestens 80ml niedrig-osmolarem Kontrastmittel (Iopromid/Iohexol) im Rahmen einer CT-Untersuchung oder Angiographie erhielten, untersucht. Die Patienten wurden in zwei Gruppen randomisiert: Gruppe 1 erhielt 300 mg Ubiquinon (120 Tropfen) täglich verteilt auf 3 Dosen à 40 Tropfen, erstmals ca. 4 Std. vor der geplanten Untersuchung (Tag 0) und bis 2 Tage danach (Tag 2) und zusätzlich 30 bis 60 Minuten vor der geplanten Untersuchung (Tag 0) 5 mg/kg KG Theophyllin intravenös als Kurzinfusion über ca. 30 Minuten; Gruppe 2 erhielt 300 mg Ubiquinon (120 Tropfen) täglich verteilt auf 3 Dosen à 40 Tropfen...

Evaluation of penicillin therapy in patients with leptospirosis and acute renal failure

DAHER,Elizabeth de Francesco; NOGUEIRA,Charlys Barbosa
Fonte: Instituto de Medicina Tropical Publicador: Instituto de Medicina Tropical
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2000 EN
Relevância na Pesquisa
96.08%
The effectiveness of specific antibiotic treatment in severe leptospirosis is still under debate. As part of a prospective study designed to evaluate renal function recovery after leptospirosis acute renal failure (ARF) (ARF was defined as Pcr > or = 1.5 mg/dL), the clinical evolutions of 16 treated patients (T) were compared to those of 18 untreated patients (nT). Treatment or non-treatment was the option of each patient's attending infectologist. The penicillin treatment was always with 6 million IU/day for 8 days. No difference was found between the two groups in terms of age, gender, number of days from onset of symptoms to hospital admission, or results of laboratory tests performed upon admission and during hospitalization, but proteinuria was higher in the treated group. There were no significant difference in the other parameters employed to evaluate patients' clinical evolution as: length of hospital stay, days of fever, days to normalization of renal function, days to total bilirubins normalized or reached 1/3 of maximum value and days to normalization of platelet counts. Dialytic treatment indication and mortality were similar between group T and nT. In conclusion, penicillin therapy did not provide better clinical outcome in patients with leptospirosis and ARF.

Incidence, risk factors and prognostic factors of acute renal failure in patients admitted to an intensive care unit

Mataloun,S.E.; Machado,F.R.; Senna,A.P.R.; Guimarães,H.P.; Amaral,J.L.G.
Fonte: Associação Brasileira de Divulgação Científica Publicador: Associação Brasileira de Divulgação Científica
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/10/2006 EN
Relevância na Pesquisa
96.13%
The objective of the present study was to assess the incidence, risk factors and outcome of patients who develop acute renal failure (ARF) in intensive care units. In this prospective observational study, 221 patients with a 48-h minimum stay, 18-year-old minimum age and absence of overt acute or chronic renal failure were included. Exclusion criteria were organ donors and renal transplantation patients. ARF was defined as a creatinine level above 1.5 mg/dL. Statistics were performed using Pearsons' chi2 test, Student t-test, and Wilcoxon test. Multivariate analysis was run using all variables with P < 0.1 in the univariate analysis. ARF developed in 19.0% of the patients, with 76.19% resulting in death. Main risk factors (univariate analysis) were: higher intra-operative hydration and bleeding, higher death risk by APACHE II score, logist organ dysfunction system on the first day, mechanical ventilation, shock due to systemic inflammatory response syndrome (SIRS)/sepsis, noradrenaline use, and plasma creatinine and urea levels on admission. Heart rate on admission (OR = 1.023 (1.002-1.044)), male gender (OR = 4.275 (1.340-13642)), shock due to SIRS/sepsis (OR = 8.590 (2.710-27.229)), higher intra-operative hydration (OR = 1.002 (1.000-1004))...

Insuficiência renal aguda secundária à síndrome compartimental abdominal: relato de quatro casos e revisão da literatura; Acute renal failure due to abdominal compartment syndrome: report on four cases and literature review

Cleva, Roberto de; Silva, Fabiano Pinheiro da; Zilberstein, Bruno; Machado, David J B
Fonte: Universidade de São Paulo. Faculdade de Medicina Publicador: Universidade de São Paulo. Faculdade de Medicina
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; ; Formato: application/pdf
Publicado em 01/08/2001 ENG
Relevância na Pesquisa
96.12%
Descrevemos quatro casos de síndrome compartimental abdominal complicadas por insuficiência renal aguda e prontamente revertidas por diferentes métodos de descompressão abdominal. Caso 1: paciente obesa de 57 anos no pós-operatório de correção de hérnia incisional gigante com pressão intra-abdominal de 24 mm Hg. Após sedação e curarização, a PIA caiu para 15 mm Hg. Caso 2: paciente de 73 anos com abdômem agudo inflamatório submetida à laparotomia exploradora quando foi diagnosticado pneumoperitôneo hipertensivo. Durante a cirurgia houve melhora da diurese. Caso 3: paciente de 18 anos submetido a hepactetomia apresentou coagulopatia e sangramento hepático necessitando tamponamento com compressas, evoluindo com oligúria e PIA de 22 mm Hg. Na reoperação, após remoção das compressas houve melhora importante do fluxo urinário. Caso 4: paciente de 46 anos com cirrose hepática foi admitido após correção de hérnia incisional com pressão intra-abdominal de 16 mm Hg. Após paracentese, a pressão intra-abdominal caiu para 11 mm Hg.; We report on 4 cases of abdominal compartment syndrome complicated by acute renal failure that were promptly reversed by different abdominal decompression methods. Case 1: A 57-year-old obese woman in the post-operative period after giant incisional hernia correction with an intra-abdominal pressure of 24 mm Hg. She was sedated and curarized...

Insuficiência renal aguda após numerosas picadas de abelhas; Acute renal failure after massive honeybee stings

Daher, Elizabeth De Francesco; Silva Junior, Geraldo Bezerra da; Bezerra, Glaydcianne Pinheiro; Pontes, Lícia Borges; Martins, Alice Maria Costa; Guimarães, José Ambrósio
Fonte: Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo Publicador: Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; ; Formato: application/pdf
Publicado em 01/01/2003 ENG
Relevância na Pesquisa
96.22%
Foram relatados dois casos clínicos de pacientes que sobreviveram a ataques maciços de abelhas africanizadas (600 e 1500 picadas). As reações caracterizaram-se por edema difuso e generalizado, sensação de queimação na pele, cefaléia, fraqueza, parestesia generalizada, sonolência e hipotensão. A insuficiência renal aguda desenvolveu-se, tendo sido atribuída à hipotensão, hemólise intravascular, mioglobinúria devido à rabdomiólise e provavelmente ao efeito tóxico direto da grande quantidade de veneno injetada. Os pacientes foram tratados com agentes anti-histamínicos, corticosteróides e reposição hídrica. Um paciente apresentou quadro grave de insuficiência renal aguda necessitando de tratamento dialítico. Nenhuma complicação clínica foi observada durante a internação e ambos evoluíram bem com recuperação completa da função renal. Assim, a insuficiência renal aguda após picadas de abelhas ocorre provavelmente devido a nefropatia por pigmentos associada à hipovolemia. O rápido reconhecimento desta síndrome é crucial para o sucesso terapêutico destes pacientes.; Two clinical cases of patients who survived after numerous attacks of Africanized bees (600 and 1500 bee stings, respectively) are reported. Clinical manifestation was characterized by diffuse and widespread edema...

Avaliação do tratamento com penicilina em pacientes com leptospirose e insuficiência renal aguda; Evaluation of penicillin therapy in patients with leptospirosis and acute renal failure

DAHER, Elizabeth de Francesco; NOGUEIRA, Charlys Barbosa
Fonte: Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo Publicador: Universidade de São Paulo. Instituto de Medicina Tropical de São Paulo
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; ; Formato: application/pdf
Publicado em 01/12/2000 ENG
Relevância na Pesquisa
96.12%
A eficácia da antibioticoterapia no tratamento da leptospirose humana tem sido motivo de discussão. Como parte de um trabalho prospectivo para avaliar a recuperação da função renal após a insuficiência renal aguda (IRA) da leptospirose (IRA definida como Pcr >; ou = 1,5 mg/dL), comparou-se a evolução clínica durante a internação de 16 pacientes, com leptospirose grave, tratados (T) com 18 não tratados (nT). O tratamento com ou sem penicilina foi opção de cada infectologista responsável pelo paciente. Quando tratados, foi administrado penicilina 6 milhões de U/dia por 8 dias. Os parâmetros analisados como idade, sexo, tempo do início dos sintomas à admissão, exames laboratoriais da admissão e internação não foram significativamente diferentes nos dois grupos, exceto pela proteinúria que foi significativamente mais elevada no grupo T. A recuperação clínica da doença avaliada pelo tempo: de internação, de febre, para função renal e níveis de plaquetas normalizarem e para os níveis de bilirrubinas totais caírem a 1/3 do valor máximo ou normalizar não foram diferentes no grupo tratado e não tratado. A indicação do tratamento dialítico e a mortalidade também não foram diferentes nos dois grupos. Conclui-se que na leptospirose com IRA o tratamento com penicilina não mudou o curso da doença.; The effectiveness of specific antibiotic treatment in severe leptospirosis is still under debate. As part of a prospective study designed to evaluate renal function recovery after leptospirosis acute renal failure (ARF) (ARF was defined as Pcr >; or = 1.5 mg/dL)...

Guidelines for specialized nutritional and metabolic support in the critically-ill patient: Update. Consensus SEMICYUC-SENPE: Acute renal failure

López Martínez,J.; Sánchez-Izquierdo Riera,J. A.; Jiménez Jiménez,F. J.
Fonte: Nutrición Hospitalaria Publicador: Nutrición Hospitalaria
Tipo: info:eu-repo/semantics/article; journal article; info:eu-repo/semantics/publishedVersion Formato: text/html; application/pdf
Publicado em 01/11/2011 ENG
Relevância na Pesquisa
96.14%
Nutritional support in acute renal failure must take into account the patient's catabolism and the treatment of the renal failure. Hypermetabolic failure is common in these patients, requiring continuous renal replacement therapy or daily hemodialysis. In patients with normal catabolism (urea nitrogen below 10 g/day) and preserved diuresis, conservative treatment can be attempted. In these patients, relatively hypoproteic nutritional support is essential, using proteins with high biological value and limiting fluid and electrolyte intake according to the patient's individual requirements. Micronutrient intake should be adjusted, the only buffering agent used being bicarbonate. Limitations on fluid, electrolyte and nitrogen intake no longer apply when extrarenal clearance techniques are used but intake of these substances should be modified according to the type of clearance. Depending on their hemofiltration flow, continuous renal replacement systems require high daily nitrogen intake, which can sometimes reach 2.5 g protein/kg. The amount of volume replacement can induce energy overload and therefore the use of glucose-free replacement fluids and glucosefree dialysis or a glucose concentration of 1 g/L, with bicarbonate as a buffer...