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"Alterações na imunidade inespecifica subsequentes à indução de estresse agudo em indivíduos com fobia social e pessoas sem patologias psiquiátricas"; Alterations in inespecific immunity subsequent to the induction of acute stress in individuals with social phobia and persons without psychiatric disorders

Faustino, Alessandra Fernandes
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 18/04/2005 PT
Relevância na Pesquisa
45.98%
As interações entre o sistema nervoso central e os sistemas imune e endócrino são o objeto de estudo da psiconeuroimunologia. Protocolos de indução de estresse têm sido amplamente utilizados como métodos confiáveis de investigação da relação entre transtornos psiquiátricos, aspectos psicológicos, traços de personalidade, ansiedade e a resposta imune. O procedimento de simulação de falar em público (SFP) é um protocolo experimental validado que reconhecidamente é capaz de ativar o eixo hipotálamo-hipófise-adrenal (HPA) e produzir respostas de estresse em sujeitos humanos. Esse método foi utilizado para: 1) Comparar a reatividade imunológica de indivíduos com diagnóstico de fobia social com a de indivíduos sem qualquer diagnóstico psiquiátrico; 2) Investigar se ocorrem alterações imunes subseqüentes à exposição a um estressor agudo induzido em laboratório e 3) identificar e correlacionar parâmetros imunológicos com traços de personalidade, humor, níveis de ansiedade e medidas fisiológicas. Os traços de personalidade foram investigados por meio dos seguintes instrumentos: Inventário de Temperamento e Caráter (TCI), Escala de Afeto Positivo e Negativo (PANAS), Inventário de Ansiedade Traço (IDATE-T)...

Influência da resposta aguda de estresse no desempenho da memória de idosos saudáveis; Influence of acute stress response on memory performance of healthy elderly.

Santos, Aline Talita dos
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 19/04/2013 PT
Relevância na Pesquisa
55.95%
Vários estudos têm sugerido que o estresse pode ser um dos fatores relacionados com à grande variabilidade cognitiva observada em idosos. Esta associação se explica porque o cortisol, principal classe de hormônios do estresse em humanos, apresenta alta afinidade por receptores específicos localizados no hipocampo, amígdala e região pré-frontal, estruturas associadas ao aprendizado e à memória. Concentrações cronicamente elevadas de cortisol estão associadas à atrofia hipocampal e baixo desempenho cognitivo. Entretanto, o efeito do estresse agudo no desempenho da memória ainda se encontra inconclusivo em idosos. Isto é particularmente relevante, uma vez que, idosos com comprometimento cognitivo patológico apresentam concentração elevada de cortisol, que por sua vez, está associada com rápida progressão da doença. Assim, o objetivo do estudo foi analisar a relação entre desempenho da memória e resposta neuroendócrina e cardiovascular de estresse em idosos saudáveis. Foram selecionados aleatoriamente 100 idosos alfabetizados, predominantemente do sexo feminino, sem prejuízo cognitivo e funcional, moradores da cidade de São Paulo. A resposta neuroendócrina de estresse foi avaliada a partir concentração de cortisol salivar enquanto que a reação cardiovascular a partir da pressão arterial e frequência cardíaca antes...

Avaliação da sensibilidade nociceptiva e do comportamento emocional após estresse agudo e crônico em ratos com inflamação persistente nas ATMs e o possível envolvimento de receptores para CRF; Evaluation of acute and chronic stress in nociceptive sensibility and emotional behavior in rats with persistent inflammation of the temporomandibular joints the possible involvement of CRF receptors

Marquezi, Ana Paula Ribeiro Novaes
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 01/08/2014 PT
Relevância na Pesquisa
46.08%
Condições músculo-esqueléticas como as desordens da articulação temporomandibular (ATM) são as principais causas de dor não odontogênica na região orofacial e incluem um grupo de condições usualmente acompanhadas de dor na região das ATMs e dos músculos mastigatórios, limitação da abertura bucal e dores de cabeça. Pacientes com desordens da articulação temporomandibular (DTM) também podem apresentar desordens relacionadas ao estresse caracterizadas por alterações somáticas e psicológicas como fadiga, distúrbios do sono, ansiedade e depressão. A causa exata das DTMs ainda não é completamente entendida, mas acredita-se que envolva fatores fisiológicos, comportamentais e ambientais. É possível que alguns sintomas de DTM e dor orofacial sejam apenas manifestações somáticas de estresse emocional. De fato, situações de estresse promovem uma série de mudanças fisiológicas e comportamentais que podem afetar os sistemas hormonais e de neurotransmissores. Estudos demonstraram que o CRF e seus receptores medeiam respostas comportamentais, endócrinas e autonômicas para o estresse, além de estar envolvidos em outras funções, como na modulação nociceptiva. O objetivo deste trabalho foi avaliar a nocicepção e o comportamento emocional em ratos com inflamação persistente nas ATMs...

Serum levels of brain-derived neurotrophic factor in acute and posttraumatic stress disorder : a case report study; Nível sérico do fator neurotrófico derivado do cérebro no transtorno de estresse agudo e no transtorno de estresse pós-traumatico : relato de casos

Hauck, Simone; Gomes, Fabiano; Silveira Júnior, Érico de Moura; Almeida, Ellen Alves de; Possa, Marianne A.; Ceitlin, Lucia Helena Freitas
Fonte: Universidade Federal do Rio Grande do Sul Publicador: Universidade Federal do Rio Grande do Sul
Tipo: Artigo de Revista Científica Formato: application/pdf
ENG
Relevância na Pesquisa
56.01%
Objetivo: O objetivo do estudo foi avaliar os níveis séricos do fator neurotrófico derivado do cérebro em um paciente com transtorno de estresse pós-traumático e em um paciente com transtorno de estresse agudo antes e após o tratamento, comparando esses níveis aos de controles saudáveis. Método: Os níveis do fator neurotrófico derivado do cérebro, a Escala Davidson de Trauma, o Inventário de Depressão de Beck, a Avaliação do Funcionamento Global e a Impressão Clínica Global foram medidos antes e após seis semanas de tratamento. Resultados: Os níveis de fator neurotrófico derivado do cérebro foram maiores nos pacientes, quando comparados aos controles, antes do tratamento. Depois de seis semanas houve redução dos sintomas e melhora do funcionamento nos dois casos. Ao mesmo tempo, houve redução dos níveis de fator neurotrófico derivado do cérebro, mesmo no caso 2, tratado exclusivamente com psicoterapia. Conclusões: Esses resultados sugerem que o fator neurotrófico derivado do cérebro está aumentado tanto no transtorno de estresse pós-traumático quanto no transtorno de estresse agudo, de forma oposta às alterações até então descritas nos transtornos do humor.; Objective: The aim of this study was to evaluate brain-derived neurotrophic factor levels in two patients...

Influência dos hormônios sexuais na analgesia induzida pelo estresse; Influence of sex hormones in stress-induced analgesia

Carlos Eduardo da Silva Nossa Tuma
Fonte: Biblioteca Digital da Unicamp Publicador: Biblioteca Digital da Unicamp
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 25/07/2011 PT
Relevância na Pesquisa
46%
As disfunções temporomandibulares compreendem um grupo variável de condições que resultam em dor articular e/ou muscular e contribuem para o desenvolvimento de dores crônicas, sendo mais prevalente em mulheres em relação aos homens, principalmente durante o período reprodutivo. Envolvem os músculos da mastigação e a articulação temporomandibular (ATM), sendo geralmente associadas a processos inflamatórios, havendo ainda a participação dos hormônios gonadais nestas disfunções. O teste da formalina na ATM é um modelo animal válido para estudos de disfunções temporomandibulares. Os objetivos desta pesquisa foram avaliar 1) o efeito do estresse agudo de 15 minutos, 30 minutos e 1 hora sobre as respostas comportamentais nociceptivas após o teste da formalina na ATM de ratas em fase de estro (baixos níveis de estrógeno) e proestro (altos níveis de estrógeno) e ratos e ratas castrados com ou sem tratamento hormonal (17ß-estradiol), 2) a participação do sistema opióide nas possíveis alterações nociceptivas induzidas por situações estressantes, e 3) a avaliação dos níveis sanguíneos de corticosterona e ansiedade após o estresse agudo. Os ratos foram castrados 60 dias após o nascimento, sendo o tratamento hormonal (17ß-estradiol sigma® - E0756 - 5 mg em óleo mineral; s.c.; 50µg/Kg/day; as nove horas da manhã) ou a administração do veículo (óleo mineral)...

Serum levels of brain-derived neurotrophic factor in acute and posttraumatic stress disorder: a case report study

Hauck,Simone; Gomes,Fabiano; Silveira Júnior,Érico de Moura; Almeida,Ellen; Possa,Marianne; Ceitlin,Lúcia Helena Freitas
Fonte: Associação Brasileira de Psiquiatria - ABP Publicador: Associação Brasileira de Psiquiatria - ABP
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/03/2009 EN
Relevância na Pesquisa
56.06%
OBJECTIVE: The aim of this study was to evaluate brain-derived neurotrophic factor levels in two patients, one with posttraumatic stress disorder and one with acute stress disorder, before and after treatment, and to compare those levels to those of healthy controls. METHOD: Brain-derived neurotrophic factor level, Davidson Trauma Scale, Beck Depression Inventory, Global Assessment of Functioning, and Clinical Global Impression were assessed before and after 6 weeks of treatment. RESULTS: Brain-derived neurotrophic factor levels were higher in patients than in matched controls before treatment. After 6 weeks, there was a reduction in symptoms and an improvement in functioning in both cases. At the same time, brain-derived neurotrophic factor levels decreased after treatment, even in case 2, treated with psychotherapy only. CONCLUSIONS: These results suggest that serum levels of brain-derived neurotrophic factor, as opposed to what has been described in mood disorders, are increased in posttraumatic stress disorder as well as in acute stress disorder.

Hippocampal long-term depression mediates acute stress-induced spatial memory retrieval impairment

Wong, Tak Pan; Howland, John G.; Robillard, Julie M.; Ge, Yuan; Yu, Wayne; Titterness, Andrea K.; Brebner, Karen; Liu, Lidong; Weinberg, Joanne; Christie, Brian R.; Phillips, Anthony G.; Wang, Yu Tian
Fonte: National Academy of Sciences Publicador: National Academy of Sciences
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
45.96%
Acute stress impairs memory retrieval and facilitates the induction of long-term depression (LTD) in the hippocampal CA1 region of the adult rodent brain. However, whether such alterations in synaptic plasticity cause the behavioral effects of stress is not known. Here, we report that two selective inhibitors of the induction or expression of stress-enabled, N-methyl-d-aspartate receptor-dependent hippocampal LTD also block spatial memory retrieval impairments caused by acute stress. Additionally, we demonstrate that facilitating the induction of hippocampal LTD in vivo by blockade of glutamate transport mimics the behavioral effects of acute stress by impairing spatial memory retrieval. Thus, the present study demonstrates that hippocampal LTD is both necessary and sufficient to cause acute stress-induced impairment of spatial memory retrieval and provides a new perspective from which to consider the nature of cognitive deficits in disorders whose symptoms are aggravated by stress.

Acute stress induces down-regulation of large-conductance Ca2+-activated potassium channels in the lateral amygdala

Guo, Yan-yan; Liu, Shui-bing; Cui, Guang-Bin; Ma, Lan; Feng, Bin; Xing, Jiang-hao; Yang, Qi; Li, Xiao-qiang; Wu, Yu-mei; Xiong, Li-ze; Zhang, Weiqi; Zhao, Ming-gao
Fonte: Blackwell Science Inc Publicador: Blackwell Science Inc
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
45.95%
Large-conductance Ca2+-activated potassium channels (BKCa) are highly expressed in the lateral amygdala (LA), which is closely involved in assigning stress disorders, but data on their role in the neuronal circuits of stress disorders are limited. In the present study, a significant reduction in BKCa channel expression in the amygdala of mice accompanied anxiety-like behaviour induced by acute stress. Whole-cell patch-clamp recordings from LA neurons of the anxious animals revealed a pronounced reduction in the fast after-hyperpolarization (fAHP) of action potentials mediated by BKCa channels that led to hyperexcitability of the LA neurons. Activation of BKCa channels in the LA reversed stress-induced anxiety-like behaviour after stress. Furthermore, down-regulated BKCa channels notably increased the evoked NMDA receptor-mediated excitatory postsynaptic potentials at the thalamo-LA synapses. These data demonstrate, for the first time, that restraint stress-induced anxiety-like behaviour could at least partly be explained by alterations in the functional BKCa channels in the LA.

Acute Stress Induces Selective Alterations in Cost/Benefit Decision-Making

Shafiei, Naghmeh; Gray, Megan; Viau, Victor; Floresco, Stan B
Fonte: Nature Publishing Group Publicador: Nature Publishing Group
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
45.97%
Acute stress can exert beneficial or detrimental effects on different forms of cognition. In the present study, we assessed the effects of acute restraint stress on different forms of cost/benefit decision-making, and some of the hormonal and neurochemical mechanisms that may underlie these effects. Effort-based decision-making was assessed where rats chose between a low effort/reward (1 press=2 pellets) or high effort/reward option (4 pellets), with the effort requirement increasing over 4 blocks of trials (2, 5, 10, and 20 lever presses). Restraint stress for 1 h decreased preference for the more costly reward and induced longer choice latencies. Control experiments revealed that the effects on decision-making were not mediated by general reductions in motivation or preference for larger rewards. In contrast, acute stress did not affect delay-discounting, when rats chose between a small/immediate vs larger/delayed reward. The effects of stress on decision-making were not mimicked by treatment with physiological doses of corticosterone (1–3 mg/kg). Blockade of dopamine receptors with flupenthixol (0.25 mg/kg) before restraint did not attenuate stress-induced effects on effort-related choice, but abolished effects on choice latencies. These data suggest that acute stress interferes somewhat selectively with cost/benefit evaluations concerning effort costs. These effects do not appear to be mediated solely by enhanced glucocorticoid activity...

Fear extinction deficits following acute stress associate with increased spine density and dendritic retraction in basolateral amygdala neurons

Maroun, Mouna; Ioannides, Pericles J.; Bergman, Krista L.; Kavushansky, Alexandra; Holmes, Andrew; Wellman, Cara L.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
45.95%
Stress-sensitive psychopathologies such as post-traumatic stress disorder are characterized by deficits in fear extinction and dysfunction of corticolimbic circuits mediating extinction. Chronic stress facilitates fear conditioning, impairs extinction, and produces dendritic proliferation in the basolateral amygdala (BLA), a critical site of plasticity for extinction. Acute stress impairs extinction, alters plasticity in the medial prefrontal cortex-to-BLA circuit, and causes dendritic retraction in the medial prefrontal cortex. Here, we examined extinction learning and basolateral amygdala pyramidal neuron morphology in adult male rats following a single elevated platform stress. Acute stress impaired extinction acquisition and memory, and produced dendritic retraction and increased mushroom spine density in basolateral amygdala neurons in the right hemisphere. Unexpectedly, irrespective of stress, rats that underwent fear and extinction testing showed basolateral amygdala dendritic retraction and altered spine density relative to non-conditioned rats, particularly in the left hemisphere. Thus, extinction deficits produced by acute stress are associated with increased spine density and dendritic retraction in basolateral amygdala pyramidal neurons. Furthermore...

Posttraumatic stress disorder: A model of the longitudinal course and the role of risk factors

McFarlane, A.
Fonte: Physicians Postgraduate Press Publicador: Physicians Postgraduate Press
Tipo: Artigo de Revista Científica
Publicado em //2000 EN
Relevância na Pesquisa
55.91%
Posttraumatic stress disorder (PTSD) differs from other anxiety disorders in that experience of a traumatic event is necessary for the onset of the disorder. The condition runs a longitudinal course, involving a series of transitional states, with progressive modification occurring with time. Notably, only a small percentage of people that experience trauma will develop PTSD. Risk factors, such as prior trauma, prior psychiatric history, family psychiatric history, peritraumatic dissociation, acute stress symptoms, the nature of the biological response, and autonomic hyperarousal, need to be considered when setting up models to predict the course of the condition. These risk factors influence vulnerability to the onset of PTSD and its spontaneous remission. In the majority of cases, PTSD is accompanied by another condition, such as major depression, an anxiety disorder, or substance abuse. This comorbidity can also complicate the course of the disorder and raises questions about the role of PTSD in other psychiatric conditions. This article reviews what is known about the emergence of PTSD following exposure to a traumatic event using data from clinical studies.

Endokrinologische Korrelate der akuten Belastungssymptomatik nach Unfalltrauma; Endocrinological correlation of acute stress reaction after physical trauma

Dahler, Dominik Philemon
Fonte: Universidade de Tubinga Publicador: Universidade de Tubinga
Tipo: Dissertação
DE_DE
Relevância na Pesquisa
65.97%
In zahlreichen Studien wurde belegt, dass traumatische Ereignisse zu psychischen Störungen führen können. Bei der Klärung der physiologischen Ätiologie dieser Störungsbilder kommt der Hypothalamus-Hypophysen-Nebennierenrinden-Achse besondere Bedeutung zu. In der vorgelegten Studie sollte überprüft werden, ob ein Zusammenhang zwischen der Ausbildung einer akuten psychischen Belastungsreaktion und der Sekretion von Katecholoaminen und Kortisol auch nach Unfällen mit moderater Verletzungsschwere zu beobachten ist. Bei 50 in die Studie eingeschlossenen Patienten wurde daher beginnend innerhalb der ersten 24 Stunden nach dem Unfallereignis eine psychologische und endokrinologische Untersuchung durchgeführt. Als psychologische Messinstrumente wurden standardisierte Fragebögen (ASDS, PDEQ) eingesetzt. Sowohl die Katecholaminsekretion als auch die Kortisolsekretion wurden im 24 Stunden-Sammelurin bestimmt Zusätzlich wurden an zwei aufeinanderfolgenden Tagen Tagesprofile der Speichelkortisolkonzentrationen erhoben. Das Kollektiv umfasste 40 Männer und zehn Frauen im Alter zwischen 18 und 67 Jahren. Die Verletzungsschwere lag im Mittel bei 5,64. Die Auswertung der psychologischen Daten ergab, dass bei sechs Patienten anhand der für den ASDS geltenden Cut-off-Werte die Diagnose einer akuten Belastungsreaktion gestellt werden konnte. Die Messung des Zusammenhangs zwischen psychischer Belastungsreaktion und endokrinologischen Daten erfolgte nach Einteilung des Kollektivs anhand des ASDS-Scores in drei demographisch vergleichbare Gruppen mit niedriger...

Estrés y variaciones en la fuerza muscular isométrica en el adulto sano. Estudio piloto

Lucas Quiroz, Andy Javier
Fonte: Universidade de Alcalá Publicador: Universidade de Alcalá
Tipo: info:eu-repo/semantics/bachelorThesis; info:eu-repo/semantics/acceptedVersion Formato: application/pdf
SPA
Relevância na Pesquisa
55.89%
Trabajo Fin de Grado (TFG); Introducción : En fisioterapia, tratar la pérdida de fuerza secundaria a una lesión o patología se considera un pilar importante dentro de la profesión. Es por ello que a ctualmente se está profundizando en el estudi o de nuevos factores que influyen en la fuerza muscular, entre ellos la exposición a estímulos que producen estrés en el individuo. En este Trabajo F in de G rado se pret ende comprobar que el estrés agudo influye y/o modifica algunos parámetros de la c ontracción muscular isométrica, de la misma forma que ocurre en la Kinesiología Aplicada que trabaja con estímulos estresantes y con el test muscular como herramienta. Objetivo : Comprobar las variaciones de la fuerza y el tiempo de mantenimiento en una co ntracción muscular isométrica en el adulto sano, ante la exposición inmediata de las Imágenes Afectivas del Sistema Internacional. Sujetos, m aterial y métodos : Estudio analítico, experimental y prospectivo. Estudio piloto con una muestra compuesta por 52 s ujetos sanos y con un nivel de estrés dentro de la normalidad, organizada en dos grupos: Grupo I (n=24 hombres) y Grupo II (n=28 mujeres) con una edad comprendida entre los 18 y 25 años. Se les realiza tres pruebas de fuerza isométrica mientras visualizan una imagen en cada prueba (en una de ellas la imagen era estresante) y se mide el pico de fuerza (F1...

Treating adults with acute stress disorder and post-traumatic stress disorder in general practice: a clinical update

Forbes, D.; Creamer, M.; Phelps, A.; Couineau, A.L.; Cooper, J.; Bryant, R.; McFarlane, A.; Devilly, G.; Matthews, L.; Raphael, B.
Fonte: Australasian Med Publ Co Ltd Publicador: Australasian Med Publ Co Ltd
Tipo: Artigo de Revista Científica
Publicado em //2007 EN
Relevância na Pesquisa
75.98%
General practitioners have an important role to play in helping patients after exposure to severe psychological trauma. In the immediate aftermath of trauma, GPs should offer "psychological first aid", which includes monitoring of the patient's mental state, providing general emotional support and information, and encouraging the active use of social support networks, and self-care strategies. Drug treatments should be avoided as a preventive intervention after traumatic exposure; they may be used cautiously in cases of extreme distress that persists. Adults with acute stress disorder (ASD) and post-traumatic stress disorder (PTSD) should be provided with trauma-focused cognitive behaviour therapy (CBT). Eye movement desensitisation and reprocessing (EMDR) in addition to in-vivo exposure (confronting avoided situations, people or places in a graded and systematic manner) may also be provided for PTSD. Drug treatments should not normally replace trauma-focused psychological therapy as a first-line treatment for adults with PTSD. If medication is considered for treating PTSD in adults, selective serotonin reuptake inhibitor antidepressants are the first choice. Other new generation antidepressants and older tricyclic antidepressants should be considered as second-line pharmacological options. Monoamine oxidase inhibitors may be considered by mental health specialists for use in people with treatment-resistant symptoms.; David Forbes...

A multisite study of the capacity of acute stress disorder diagnosis to predict posttraumatic stress disorder

Bryant, R.; Creamer, M.; O'Donnell, M.; Silove, D.; McFarlane, A.
Fonte: Physicians Postgraduate Press Publicador: Physicians Postgraduate Press
Tipo: Artigo de Revista Científica
Publicado em //2008 EN
Relevância na Pesquisa
76.05%
OBJECTIVE: Previous studies investigating the relationship between acute stress disorder (ASD) and posttraumatic stress disorder (PTSD) have reported mixed findings and have been flawed by small sample sizes and single sites. This study addresses these limitations by conducting a large-scale and multisite study to evaluate the extent to which ASD predicts subsequent PTSD. METHOD: Between April 2004 and April 2005, patients admitted consecutively to 4 major trauma hospitals across Australia (N = 597) were randomly selected and assessed for ASD (DSM-IV criteria) during hospital admission (within 1 month of trauma exposure) and were subsequently reassessed for PTSD 3 months after the initial assessment (N = 507). RESULTS: Thirty-three patients (6%) met criteria for ASD, and 49 patients (10%) met criteria for PTSD at the 3-month follow-up assessment. Fifteen patients (45%) diagnosed with ASD and 34 patients (7%) not diagnosed with ASD subsequently met criteria for PTSD. The positive predictive power of PTSD criteria in the acute phase (0.60) was a better predictor of chronic PTSD than the positive predictive power of ASD (0.46). CONCLUSIONS: The majority of people who develop PTSD do not initially meet criteria for ASD. These data challenge the proposition that the ASD diagnosis is an adequate tool to predict chronic PTSD.; http://www.psychiatrist.com/abstracts/abstracts.asp?abstract=200806/060806.htm; Richard A. Bryant...

A confirmatory factor analysis of the Acute Stress Disorder Interview

Brooks, R.; Silove, D.; Bryant, R.; O'Donnell, M.; Creamer, M.; McFarlane, A.
Fonte: Kluwer Academic/Plenum Publ Publicador: Kluwer Academic/Plenum Publ
Tipo: Artigo de Revista Científica
Publicado em //2008 EN
Relevância na Pesquisa
76.09%
Acute stress disorder (ASD) was introduced in 1994 to describe posttraumatic stress reactions that occur in the initial month after trauma exposure. Although it comprises the distinct symptom clusters of dissociation, reexperiencing, avoidance, and arousal, there have been no confirmatory factor analyses of the construct. In this study, 587 individuals admitted to five major hospitals after traumatic injury were administered the Acute Stress Disorder Interview. Forty-four participants met criteria for ASD. Confirmatory factor analysis based on the four symptom clusters described the Acute Stress Disorder Interview responses. These data provide the first confirmatory factor analysis of the ASD symptoms, and are discussed in terms of the 4-factor models repeatedly found in samples of chronic posttraumatic stress disorder.; Robert Brooks and Derrick Silove; Richard Bryant; Meaghan O’Donnell and Mark Creamer; Alexander McFarlane; Published in Journal of Traumatic Stress, 2008; 21 (3):352-355 at www.interscience.wiley.com Copyright © 2008 International Society for Traumatic Stress Studies.

The capacity of acute stress disorder to predict posttraumatic psychiatric disorders

Bryant, R.; Creamer, M.; O'Donnell, M.; Silove, D.; McFarlane, A.
Fonte: Pergamon-Elsevier Science Ltd Publicador: Pergamon-Elsevier Science Ltd
Tipo: Artigo de Revista Científica
Publicado em //2012 EN
Relevância na Pesquisa
76.04%
BACKGROUND: One rationale for establishing the acute stress disorder diagnosis was to identify recently trauma-exposed people who may develop later posttraumatic stress disorder (PTSD). This study conducted a multi-site assessment of the extent to which ASD predicts subsequent PTSD, and also major depressive disorder, panic disorder, agoraphobia, social phobia, specific phobia, generalized anxiety disorder, and substance use disorder, 12 months after trauma. METHOD: Consecutive admissions to 5 major trauma hospitals across Australia (N = 1084) were assessed during hospital admission and within one month of trauma exposure and subsequently re-assessed for psychiatric disorder 12 months after the initial assessment (N = 859). RESULTS: Whereas 120 (10%) patients met criteria for ASD in the initial month after trauma, 83 (10%) met criteria for PTSD, and 268 (31%) had any psychiatric disorder at 12 months. In terms of those diagnosed with ASD, 28 (36%) subsequently met criteria for PTSD and 50 (65%) subsequently developed any psychiatric disorder. CONCLUSIONS: Whereas the majority of people with ASD subsequently develop a psychiatric disorder, most people with a disorder at 12 months do not initially display ASD.; Richard A. Bryant...

Symptomatology and psychopathology of mental health problems after disaster

Foa, E.; Stein, D.; McFarlane, A.
Fonte: Physicians Postgraduate Press Publicador: Physicians Postgraduate Press
Tipo: Artigo de Revista Científica
Publicado em //2006 EN
Relevância na Pesquisa
45.95%
A variety of reactions are observed after a major trauma. In the majority of cases these resolve without any long-term consequences. In a significant proportion of individuals, however, recovery may be impaired, leading to long-term pathological disturbances. The most common of these is post-traumatic stress disorder (PTSD), which is characterized by symptoms of reexperiencing the trauma, avoidance and numbing, and hyperarousal. A range of other disorders may also be seen after trauma, and there is considerable overlap between PTSD symptoms and several other psychiatric conditions. Risk factors for PTSD include severe exposure to the trauma, female sex, low socioeconomic status, and a history of psychiatric illness. Although PTSD may resolve in the majority of cases, in some cases risk factors outweigh protective factors, and symptoms may persist for many years. PTSD often coexists with other psychiatric disorders, such as depression, anxiety disorders, and substance abuse, and with physical (somatization) symptoms. There is growing evidence that PTSD does not merely represent a normal response to stress, but rather is mediated by specific neurobiological dysfunctions.; http://www.psychiatrist.com/abstracts/abstracts.asp?abstract=2006s02/s020602.htm; Edna B. Foa...

A comparison of the capacity of DSM-IV and DSM-5 acute stress disorder definitions to predict posttraumatic stress disorder and related disorders

Bryant, R.A.; Creamer, M.; O'Donnell, M.; Silove, D.; McFarlane, A.C.; Forbes, D.
Fonte: Physicians Postgraduate Press Publicador: Physicians Postgraduate Press
Tipo: Artigo de Revista Científica
Publicado em //2015 EN
Relevância na Pesquisa
76.11%
OBJECTIVE: This study addresses the extent to which DSM-IV and DSM-5 definitions of acute stress disorder (ASD) predict subsequent posttraumatic stress disorder (PTSD) and related psychiatric disorders following trauma. METHOD: Patients with randomized admissions to 5 hospitals across Australia (N = 596) were assessed in hospital and reassessed for PTSD at 3 (n = 508), 12 (n = 426), 24 (n = 439), and 72 (n = 314) months using the Clinician-Administered PTSD Scale; DSM-IV definition of PTSD was used at each assessment, and DSM-5 definition was used at 72 months. The Mini-International Neuropsychiatric Interview (MINI) was used at each assessment to assess anxiety, mood, and substance use disorders. RESULTS: Forty-five patients (8%) met DSM-IV criteria, and 80 patients (14%) met DSM-5 criteria for ASD. PTSD was diagnosed in 93 patients (9%) at 3, 82 patients (10%) at 12, 100 patients (12%) at 24, and 26 patients (8%) at 72 months; 19 patients (6%) met DSM-5 criteria for PTSD at 72 months. Comparable proportions of those diagnosed with ASD developed PTSD using DSM-IV (3 months = 46%, 12 months = 39%, 24 months = 32%, and 72 months = 25%) and DSM-5 (43%, 42%, 33%, and 24%) ASD definitions. Sensitivity was improved for DSM-5 relative to DSM-IV for depression (0.18 vs 0.30)...

Transtornos de estrés agudo y postraumático; Acute and Post-traumatic Stress Disorder; Transtornos de estresse agudo e pós-traumático

Serafim, Paula Maria; Mello, Marcelo Feijó de
Fonte: Universidade de São Paulo. Escola de Enfermagem de Ribeirão Preto Publicador: Universidade de São Paulo. Escola de Enfermagem de Ribeirão Preto
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; Formato: application/pdf
Publicado em 01/11/2010 POR
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Acute and post-traumatic stress disorders are two conditions caused specifically by violence. These are severe disorders, with deep biological, psychological and social effects. The Program to assist in and study violence (PROVE) was created in 2004. As of May 2009 the assistance changed to a multidisciplinary approach. A total 1,445 cases were seen between that date and November 2009, and new patients were included, 76 adults and 27 children. The most common traumatic events were hold-ups and kidnapping (adults) and murder of a relative and sexual abuse (children). The multidisciplinary system is effective with high adherence (87%/6 months).; Os transtornos de estresse agudo e de estresse pós-traumático são duas condições específicas causadas pela violência. São quadros graves, com repercussões biológicas, psicológicas e sociais profundas. Foi criado programa para atender e estudar a violência (Prove), em 2004. A partir de maio de 2009, houve mudança do atendimento que passou a ser multidisciplinar. Foram realizados 1.445 atendimentos dessa data até novembro de 2009 e incluídos 76 novos pacientes adultos e 27 crianças. Os eventos traumáticos mais frequentes foram assalto e sequestro (adultos) e assassinato de um familiar e abuso sexual (crianças). O sistema multidisciplinar é efetivo e apresenta alta adesão (87%/6 meses).; Los transtornos de estrés agudo y de estrés postraumático son dos condiciones específicas causadas por la violencia. Son cuadros graves...