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Physiological assessment of head-out aquatic exercises in healthy subjects: a qualitative review

Barbosa, Tiago M.; Marinho, D.A.; Reis, V.M.; Silva, A.J.; Bragada, José A.
Fonte: Instituto Politécnico de Bragança Publicador: Instituto Politécnico de Bragança
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
36.05%
In the last decades head-out aquatic exercises became one of the most important physical activities within the health system. Massive research has been produced throughout these decades in order to better understand the role of head-out aquatic exercises in populations’ health. Such studies aimed to obtain comprehensive knowledge about the acute and chronic response of subjects performing head-out aquatic exercises. For that, it is assumed that chronic adaptations represent the accumulation of acute responses during each aquatic session. The purpose of this study was to describe the “state of the art” about physiological assessment of head-out aquatic exercises based on acute and chronic adaptations in healthy subjects based on a qualitative review. The main findings about acute response of head-out aquatic exercise according to water temperature, water depth, type of exercise, additional equipment used, body segments exercising and music cadence will be described. In what concerns chronic adaptations, the main results related to cardiovascular and metabolic adaptations, muscular strength, flexibility and body composition improvements will be reported.

Behavioral effects of acute stimulation of kappa-opioid receptors during lactation

TEODOROV, Elizabeth; TOMITA, Aline T.; BANON, Gabriela P. R.; GIL, Lara G.; BERNARDI, Maria M.; FELICIO, Luciano F.
Fonte: PERGAMON-ELSEVIER SCIENCE LTD Publicador: PERGAMON-ELSEVIER SCIENCE LTD
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
35.85%
The behavioral effects of the K-opioid receptor agonist U69593 were examined in lactating rats. On day 5 of lactation, animals were treated with 0.1 mg/kg of U69593 to determine whether it influences general activity and maternal latencies toward pups. Because little attention has been given to the possibility that pre-mating treatment with morphine may modulate the response to K-opioid receptor stimulation, another group of animals was submitted to the same acute challenge after abrupt withdrawal from repeated treatment with morphine sulfate during the pre-mating period (5 mg/kg on alternate days for a total of five doses). Acute F;opioid stimulation reduced total locomotion, rearing frequency, and time spent self-grooming and increased immobility duration. These K agonist effects were not observed in animals pretreated with morphine. Similarly, latencies to retrieve pups were longer only in animals pretreated with saline and challenged acutely with U69593. None of these effects were observed in morphine sulfate-pretreated animals. The present results suggest that pre-mating repeated exposure to morphine produces a tolerance-like effect on behavioral responses to low-dose K-opioid receptor stimulation in active reproductive females. (c) 2008 Elsevier Inc. All rights reserved.; CAPES; CNPq; CNPq Conselho Nacional de Desenvolvimento Cientifico e Tecnologico[119306/2004-2]; FAPESP Fundacao de Amparo a Pesquisa do Estado de Sao Paulo[2004/05557-4]

Physical exercise and pancreatic islets Acute and chronic actions on insulin secretion

Almeida, Felipe Natali; Proença, André Ricardo Gomes de; Chimin, Patricia; Marcal, Anderson C.; Lima, Fabio Bessa; Carvalho, Carla Roberta de Oliveira
Fonte: LANDES BIOSCIENCE; AUSTIN Publicador: LANDES BIOSCIENCE; AUSTIN
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
35.94%
Diabetes mellitus (DM) is a great public health problem, which attacks part of the world population, being characterized by an imbalance in body glucose homeostasis. Physical exercise is pointed as a protective agent and is also recommended to people with DM. As pancreatic islets present an important role in glucose homeostasis, we aim to study the role of physical exercise (chronic adaptations and acute responses) in pancreatic islets functionality in Wistar male rats. First, animals were divided into two groups: sedentary (S) and aerobic trained (T). At the end of 8 weeks, half of them (S and T) were submitted to an acute exercise session (exercise until exhaustion), being subdivided as acute sedentary (AS) and acute trained (AT). After the experimental period, periepididymal, retroperitoneal and subcutaneous fat pads, blood, soleus muscle and pancreatic islets were collected and prepared for further analysis. From the pancreatic islets, total insulin content, insulin secretion stimulated by glucose, leucine, arginine and carbachol were analyzed. Our results pointed that body adiposity and glucose homeostasis improved with chronic physical exercise. In addition, total insulin content was reduced in group AT, insulin secretion stimulated by glucose was reduced in trained groups (T and AT) and insulin secretion stimulated by carbachol was increased in group AT. There were no significant differences in insulin secretion stimulated by arginine and leucine. We identified a possible modulating action on insulin secretion...

Eficácia dos exercícios de adaptação do reflexo vestíbulo-ocular no tratamento da vertigem aguda; Efficacy of vestibulo-ocular reflex exercises in the treatment of acute vertigo

Venosa, Alessandra Ramos
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 03/08/2005 PT
Relevância na Pesquisa
26.07%
Introdução: Desde sua primeira descrição na década de 40 o espectro de aplicação da reabilitação vestibular vem crescendo, tornando-se opção de tratamento em disfunções vestibulares periféricas, incluindo as uni e bilaterais, e em doenças do sistema nervoso central. O presente estudo avalia a eficácia de exercícios que estimulam a adaptação do reflexo vestíbulo-ocular em indivíduos com quadro agudo de vertigem. Métodos: neste estudo clínico prospectivo foram avaliados indivíduos aleatoriamente alocados em um grupo de estudo, que realizou exercícios para adaptação do reflexo vestíbulo-ocular, e em um grupo controle, que realizou exercícios placebo. Os critérios de inclusão foram história de pelo menos um episódio de vertigem nos últimos cinco dias, idade acima de 18 anos, e alteração em pelo menos dois dos testes objetivos de equilíbrio (teste de Romberg, teste de Fukuda e "head-shaking" nistagmo) e/ou presença de nistagmo espontâneo. Os pacientes de ambos os grupos foram orientados a utilizar dimenidrato na dose máxima de 150 mg ao dia, divididas em três doses, podendo auto-regular a dose conforme a intensidade dos sintomas apresentados. Foram excluídos indivíduos que tivessem utilizado medicação com ação no sistema vestibular nos últimos sete dias...

Adaptation to different noninvasive ventilation masks in critically ill patients

Silva,Renata Matos da; Timenetsky,Karina Tavares; Neves,Renata Cristina Miranda; Shigemichi,Liane Hirano; Kanda,Sandra Sayuri; Maekawa,Carla; Silva,Eliezer; Eid,Raquel Afonso Caserta
Fonte: Sociedade Brasileira de Pneumologia e Tisiologia Publicador: Sociedade Brasileira de Pneumologia e Tisiologia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/08/2013 EN
Relevância na Pesquisa
26.15%
OBJECTIVE: To identify which noninvasive ventilation (NIV) masks are most commonly used and the problems related to the adaptation to such masks in critically ill patients admitted to a hospital in the city of São Paulo, Brazil. METHODS: An observational study involving patients ≥ 18 years of age admitted to intensive care units and submitted to NIV. The reason for NIV use, type of mask, NIV regimen, adaptation to the mask, and reasons for non-adaptation to the mask were investigated. RESULTS: We evaluated 245 patients, with a median age of 82 years. Acute respiratory failure was the most common reason for NIV use (in 71.3%). Total face masks were the most commonly used (in 74.7%), followed by full face masks and near-total face masks (in 24.5% and 0.8%, respectively). Intermittent NIV was used in 82.4% of the patients. Adequate adaptation to the mask was found in 76% of the patients. Masks had to be replaced by another type of mask in 24% of the patients. Adequate adaptation to total face masks and full face masks was found in 75.5% and 80.0% of the patients, respectively. Non-adaptation occurred in the 2 patients using near-total facial masks. The most common reason for non-adaptation was the shape of the face...

Three-dimensional scanning with dual-source computed tomography in patients with acute skeletal trauma

Yildirim,Duzgun; Tamam,Cuneyt; Gumus,Terman
Fonte: Faculdade de Medicina / USP Publicador: Faculdade de Medicina / USP
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2010 EN
Relevância na Pesquisa
35.89%
OBJECTIVE: The aim of this study was to compare the efficiency of multiplanar reformatted images and threedimensional images created after multidetector computed tomography examination in detecting acute posttraumatic osseous pathology of the skeletal system. METHOD: Between October 2006 and December 2008, 105 patients with a history of acute trauma were referred to our service. Patients were evaluated with multidetector computed tomography using multiplanary reconstructed images initially (R-I), and six months after this initial evaluation, three-dimensional images were assessed of each patient (R-II). Axial images were used for guiding as a reference Data obtained was recorded and graded according to importance levels of the pathologies. RESULTS: The R-II score was higher in the non-articular and highest in periartricular fractures of the extremities, and thoracic and pelvic cage injuries. For the spinal column, while R-I data was more significant In patients referred with polytrauma, R-II data, was more statistically significant, for short processing and adaptation time to acquiring immediate critical information. For all cases it was seen that three dimensional scans were more efficient in providing the orientation, within a short time. CONCLUSION: By dual source multidedector tomography systems trauma patients may be evaluated by multiplanary and three dimensionally reconstructed images. When used correctly...

Acute Functional Adaptation to Nephron Loss: Micropuncture Studies

Dirks, J.H.; Wong, N.L.M.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em //1978 EN
Relevância na Pesquisa
36.03%
The renal and proximal tubule response to contralateral kidney exclusion was studied in a variety of circumstances. Recollection micropuncture studies were performed to assess the response to contralateral kidney clamping in the normal or a remnant kidney of the dog. Acute clamping of the contralateral kidney for a normal and unilateral remnant kidney resulted in marked reduction in proximal TF/P inulin ratios in the experimental kidney reflecting a 15 percent reduction in fluid reabsorption. Mean fractional excretion of sodium, potassium and water increased significantly in remnant kidney dogs but no significant change was observed in normal dogs except for potassium excretion. The marked reduction in proximal reabsorption occurred as soon as 5-15 minutes after contralateral kidney clamping and was compensated by distal reabsorption. Acute obstruction of the contralateral ureter results in a similar markedly reduced proximal tubular reabsorption. The reduction in proximal reabsorption induced by contralateral clamping occurred in the presence of reduced perfusion pressure and volume expansion and to some extent with renal denervation. When prostaglandin E2 or acetycholine were infused prior to contralateral kidney clamping, proximal reabsorption remained at control levels and the contralateral clamping response was blocked. Similar blockade occurred after treatment with indomethacin. Acute reduction in nephron mass causes a marked depression of proximal tubular sodium and fluid absorption not obviously accounted for by hemodynamicphysical factors and humoral factors may be involved. The level of distal reabsorption to increased proximal delivery following contralateral clamping...

Genome-Wide Fitness and Expression Profiling Implicate Mga2 in Adaptation to Hydrogen Peroxide

Kelley, Ryan; Ideker, Trey
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
26.11%
Caloric restriction extends lifespan, an effect once thought to involve attenuation of reactive oxygen species (ROS) generated by aerobic metabolism. However, recent evidence suggests that caloric restriction may in fact raise ROS levels, which in turn provides protection from acute doses of oxidant through a process called adaptation. To shed light on the molecular mechanisms of adaptation, we designed a series of genome-wide deletion fitness and mRNA expression screens to identify genes involved in adaptation to hydrogen peroxide. Combined with known transcriptional interactions, the integrated data implicate Yap1 and Skn7 as central transcription factors of both the adaptive and acute oxidative responses. They also identify the transcription factors Mga2 and Rox1 as active exclusively in the adaptive response and show that Mga2 is essential for adaptation. These findings are striking because Mga2 and Rox1 have been thought to control the response to hypoxic, not oxidative, conditions. Expression profiling of mga2Δ and rox1Δ knockouts shows that these factors most strongly regulate targets in ergosterol, fatty-acid, and zinc metabolic pathways. Direct quantitation of ergosterol reveals that its basal concentration indeed depends on Mga2...

Constrained Pattern of Viral Evolution in Acute and Early HCV Infection Limits Viral Plasticity

Pfafferott, Katja; Gaudieri, Silvana; Ulsenheimer, Axel; James, Ian; Heeg, Malte; Nolan, David; John, Mina; Rauch, Andri; Mallal, Simon; Lucas, Andrew; Klenerman, Paul; Diepolder, Helmut M.; Lucas, Michaela
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
Publicado em 08/02/2011 EN
Relevância na Pesquisa
26.1%
Cellular immune responses during acute Hepatitis C virus (HCV) and HIV infection are a known correlate of infection outcome. Viral adaptation to these responses via mutation(s) within CD8+ T-cell epitopes allows these viruses to subvert host immune control. This study examined HCV evolution in 21 HCV genotype 1-infected subjects to characterise the level of viral adaptation during acute and early HCV infection. Of the total mutations observed 25% were within described CD8+ T-cell epitopes or at viral adaptation sites. Most mutations were maintained into the chronic phase of HCV infection (75%). The lack of reversion of adaptations and high proportion of silent substitutions suggests that HCV has structural and functional limitations that constrain evolution. These results were compared to the pattern of viral evolution observed in 98 subjects during a similar phase in HIV infection from a previous study. In contrast to HCV, evolution during acute HIV infection is marked by high levels of amino acid change relative to silent substitutions, including a higher proportion of adaptations, likely reflecting strong and continued CD8+ T-cell pressure combined with greater plasticity of the virus. Understanding viral escape dynamics for these two viruses is important for effective T cell vaccine design.

Oxidative Stress Adaptation with Acute, Chronic and Repeated Stress

Pickering, Andrew M.; Vojtovich, Lesya; Tower, John; Davies, Kelvin J. A.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
EN
Relevância na Pesquisa
26.18%
Oxidative stress adaptation or hormesis is an important mechanism by which cells and organisms respond to, and cope with, environmental and physiological shifts in the level of oxidative stress. Most studies of oxidative stress adaption have been limited to adaptation induced by acute stress. In contrast, many if not most environmental and physiological stresses are either repeated or chronic. In this study we find that both cultured mammalian cells, and the fruit fly Drosophila melanogaster, are capable of adapting to chronic or repeated stress by up-regulating protective systems, such as their proteasomal proteolytic capacity to remove oxidized proteins. Repeated stress adaptation resulted in significant extension of adaptive responses. Repeated stresses must occur at sufficiently long intervals, however (12 hours or more for MEF cells and 7 days or more for flies), for adaptation to be successful, and the level of both repeated and chronic stress must be lower than is optimal for adaptation to acute stress. Regrettably, regimens of adaptation to both repeated and chronic stress that were successful for short-term survival in Drosophila, nevertheless also caused significant reductions in lifespan for the flies. Thus, although both repeated and chronic stress can be tolerated...

Influência do hipoestrogenismo por ooforectomia na adaptação antioxidante em ratas wistar exercitadas regularmente

Marcedo, Ulisvaldo Brunno de Oliveira
Fonte: Universidade Federal do Rio Grande do Norte; BR; UFRN; Programa de Pós-Graduação em Ciências Farmacêuticas; Bioanálises e Medicamentos Publicador: Universidade Federal do Rio Grande do Norte; BR; UFRN; Programa de Pós-Graduação em Ciências Farmacêuticas; Bioanálises e Medicamentos
Tipo: Dissertação Formato: application/pdf
POR
Relevância na Pesquisa
26.08%
Post-menopause is a period of women s life cycle that is characterized by estrogen depletion and therefore increasing cardiovascular diseases, neurodegenerative disorders, urogenital atrophy, osteoporosis, hot flushes and sexual discomfort incidences. Estrogen is a hormone with comfirmed antioxidant action and its depletion is related to oxidative stress instalation and damaging various important biomolecules. Regular physical activity has been identified as a factor involved in reducing women s post-menopausal complications in addition to improving antioxidant defense by reducing the oxidative damage and consequently improving life s quality in this part of the population. This study aims to evaluate the influence of hypoestrogenism in antioxidant adaptation due to regular exercise, by determining reduced glutathione (GSH) and Thiobarbituric Acid Reactive Substances (SRAT) concentrations and antioxidant enzymes glutathione peroxidase (GPx), Superoxide Dismutase (SOD) and Catalase (CAT) activities in blood, brain and liver of rats. To achieve this goal we used 50 Wistar rats, weighing 180-250g which were divided into two groups, control - GC (25) and ooforectomized - GO (25). Each group was subdivided into five subgroups: Not-trained - S (5)...

Par??metros Metab??licos e Ruminais de Ovelhas Induzidas ?? Acidose Ruminal Sub-Cl??nica, Suplementadas com Probi??tico, Monensina e Sel??nio Levedura; Ruminal and metabolic parameters of sheep induced to sub-acute ruminal acidosis and fed with probiotic, monensin and selenium yeast

SCHWEGLER, Elizabeth
Fonte: Universidade Federal de Pelotas; Veterin??ria; Programa de P??s-Gradua????o em Veterin??ria; UFPel; BR Publicador: Universidade Federal de Pelotas; Veterin??ria; Programa de P??s-Gradua????o em Veterin??ria; UFPel; BR
Tipo: Dissertação Formato: application/pdf
POR
Relevância na Pesquisa
36.03%
The aim of this study was to observe the efficiency of probiotics, monensin and selenium yeast fed to sheep induced to sub-acute ruminal acidosis (SARA) on the maintenance of normal ruminal and metabolic parameters. Thirty six sheep that averaged 12 months old and 31 ?? 8 kg of body weight were used. The sheep were kept in a confinement system, receiving a diet based on tifton hay (Cynodon sp.) and concentrate. The sheep were divided in six groups, each one containing six animals. The treatments were: CO group, control, receiving the diet without any supplement; CS, with the addition of 1.5 g/animal/day of Sel-Plex?? (selenium yeast); CM, with the addition of 11 ppm/kg of diet dry matter (DM) of monensin; CSM, with the addition of 11 ppm/kg of diet DM of monensin and 1.5 g/animal/day of Sel-Plex??; CY, with the addition of 3 g/animal/day of Yea-Sacc?? (probiotic Saccharomyces cerevisiae); CSY, with the addition 3 g/animal/day of Yea-Sacc?? and 1.5 g/animal/day of Sel-Plex??. The sheep receive this diet for 21 days before the start of the experiment. After the adaptation period the sheep were submitted to 2 days of fasting, receiving just the supplement and water ad libitum. After this, the sheep were submitted to 4 days of induced SARA...

Two Adaptation Mechanisms Regulate Cellular Migration in Dictyostelium discouideum

Rodriguez, Marbelys
Fonte: FIU Digital Commons Publicador: FIU Digital Commons
Tipo: Artigo de Revista Científica Formato: application/pdf
Relevância na Pesquisa
36.04%
Dictyostelium discoideum is a simple model widely used to study many cellular functions, including differentiation, gene regulation, cellular trafficking and directional migration. Adaptation mechanisms are essential in the regulation of these cellular processes. The misregulation of adaptation components often results in persistent activation of signaling pathways and aberrant cellular responses. Studying adaptation mechanisms regulating cellular migration will be crucial in the treatment of many pathological conditions in which motility plays a central role, such as tumor metastasis and acute inflammation. I will describe two adaptation mechanisms regulating directional migration in Dictyostelium cells. The Extracellular signal Regulated Kinase 2 (ERK2) plays an essential role in Dictyostelium cellular migration. ERK2 stimulates intracellular cAMP accumulation in chemotaxing cells. Aberrant ERK2 regulation results in aberrant cAMP levels and defective directional migration. The MAP Phosphatase with Leucine-rich repeats (MPL1) is crucial for ERK2 adaptation. Cells lacking, MPL1 (mpl1- cells) displayed higher pre-stimulus and persistent post-stimulus ERK2 phosphorylation, defective cAMP production and reduced cellular migration. Reintroduction of a full length Mpl1 into mpl1- cells restored aggregation...

Food security implications of failure of autonomous crop adaptation to extreme flood events: a case study in Bangladesh

Younus, M.A.; Bedford, R.; Morad, M.
Fonte: Bangladesh Unnayan Parishad Publicador: Bangladesh Unnayan Parishad
Tipo: Artigo de Revista Científica
Publicado em //2007 EN
Relevância na Pesquisa
35.89%
Climate change has significant implications for flooding in Bangladesh. As a consequence, millions of farmers of Bangladesh have experienced three great floods in 1988, 1995 and 1998 and have demonstrated resilience to flooding in the form of autonomous crop adaptations. However, the severity of events has meant that, where these adaptations have collapsed, millions of marginal farmers have become vulnerable, and faced acute shortage of the prime crop aman. The cumulative effects of food shortage pose obvious threats to food security, and as a consequence, human security in Bangladesh is also at threat. Farmers have employed a wide range of in-built, routine and tactical adjustments in the endeavour to revive some crop production during the huge floods. The multiple peak flows of the 1998 flood compromised most of these adjustments, and it was one of the most destructive flood events for the farmers in Islampur (a case study area) could recall for 50 or more years. An important finding was that the success of autonomous adjustment strategies is very much influenced by the nature of the flood event in terms of timing to encounter the onset of flooding, the depth of the flood waters, the duration (time flood waters stayed on the crop lands)...

A confirmatory factor analysis of the Acute Stress Disorder Interview

Brooks, R.; Silove, D.; Bryant, R.; O'Donnell, M.; Creamer, M.; McFarlane, A.
Fonte: Kluwer Academic/Plenum Publ Publicador: Kluwer Academic/Plenum Publ
Tipo: Artigo de Revista Científica
Publicado em //2008 EN
Relevância na Pesquisa
35.91%
Acute stress disorder (ASD) was introduced in 1994 to describe posttraumatic stress reactions that occur in the initial month after trauma exposure. Although it comprises the distinct symptom clusters of dissociation, reexperiencing, avoidance, and arousal, there have been no confirmatory factor analyses of the construct. In this study, 587 individuals admitted to five major hospitals after traumatic injury were administered the Acute Stress Disorder Interview. Forty-four participants met criteria for ASD. Confirmatory factor analysis based on the four symptom clusters described the Acute Stress Disorder Interview responses. These data provide the first confirmatory factor analysis of the ASD symptoms, and are discussed in terms of the 4-factor models repeatedly found in samples of chronic posttraumatic stress disorder.; Robert Brooks and Derrick Silove; Richard Bryant; Meaghan O’Donnell and Mark Creamer; Alexander McFarlane; Published in Journal of Traumatic Stress, 2008; 21 (3):352-355 at www.interscience.wiley.com Copyright © 2008 International Society for Traumatic Stress Studies.

Aortic wall properties and baroreceptor behaviour at normal arterial pressure and in acute hypertensive resetting in dogs.

Coleridge, H M; Coleridge, J C; Poore, E R; Roberts, A M; Schultz, H D
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /05/1984 EN
Relevância na Pesquisa
26.13%
In order to throw light on the mechanism of acute hypertensive baroreceptor resetting, we examined the relationship between aortic baroreceptor firing and aortic wall properties in anaesthetized dogs as pressure was varied in a number of ways. We recorded baroreceptor impulses from the left aortic nerve, and measured aortic pressure with a catheter-tip transducer and external aortic diameter with ultrasonic transit-time transducers. Narrow anticlockwise hysteresis loops were evident in the pressure-diameter relationship of the upper thoracic aorta, both during the rapid pulsatile pressure changes of the cardiac cycle and during the slow excursions of mean pressure imposed for construction of baroreceptor pressure--response curves. In contrast to the 'phase-lag' response of diameter to pressure, the baroreceptor response was 'phaselead' in character, decreasing when stress-induced creep occurred in the aortic wall. When the mean arterial pressure set-point was increased from 100 to 125 mmHg for 20 min, the hysteresis loops relating mean diameter to mean pressure in the range 60-200 mmHg were displaced along the diameter axis in the direction of wall creep. A reduction in the baroreceptor response to pressure (i.e. resetting) always accompanied this displacement. Administration of ouabain (25-35 micrograms/kg) had no consistent effect on baroreceptor resetting. It has been suggested that acute baroreceptor resetting is akin to adaptation. To investigate the possibility that the two processes are accompanied by similar changes in aortic wall properties...

Acute response and chronic stimulus for cardiac structural and functional adaptation in a professional boxer

Oxborough, David; George, Keith; Utomi, Victor; Lord, Rachel; Morton, James; Jones, Nigel; Somauroo, John
Fonte: Oxford University Press Publicador: Oxford University Press
Tipo: Artigo de Revista Científica
Publicado em 27/06/2014 EN
Relevância na Pesquisa
26.13%
The individual response to acute and chronic changes in cardiac structure and function to intense exercise training is not fully understood and therefore evidence in this setting may help to improve the timing and interpretation of pre-participation cardiac screening. The following case report highlights an acute increase in right ventricular (RV) size and a reduction in left ventricular (LV) basal radial function with concomitant increase at the mid-level in response to a week's increase in training volume in a professional boxer. These adaptations settle by the second week; however, chronic physiological adaptation occurs over a 12-week period. Electrocardiographic findings demonstrate an acute lateral T-wave inversion at 1 week, which revert to baseline for the duration of training. It appears that a change in training intensity and volume generates an acute response within the RV that acts as a stimulus for chronic adaptation in this professional boxer.

Three-dimensional scanning with dual-source computed tomography in patients with acute skeletal trauma

Yildirim, Duzgun; Tamam, Cuneyt; Gumus, Terman
Fonte: Universidade de São Paulo. Faculdade de Medicina Publicador: Universidade de São Paulo. Faculdade de Medicina
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; ; ; Formato: application/pdf
Publicado em 01/01/2010 ENG
Relevância na Pesquisa
35.89%
OBJECTIVE: The aim of this study was to compare the efficiency of multiplanar reformatted images and threedimensional images created after multidetector computed tomography examination in detecting acute posttraumatic osseous pathology of the skeletal system. METHOD: Between October 2006 and December 2008, 105 patients with a history of acute trauma were referred to our service. Patients were evaluated with multidetector computed tomography using multiplanary reconstructed images initially (R-I), and six months after this initial evaluation, three-dimensional images were assessed of each patient (R-II). Axial images were used for guiding as a reference Data obtained was recorded and graded according to importance levels of the pathologies. RESULTS: The R-II score was higher in the non-articular and highest in periartricular fractures of the extremities, and thoracic and pelvic cage injuries. For the spinal column, while R-I data was more significant In patients referred with polytrauma, R-II data, was more statistically significant, for short processing and adaptation time to acquiring immediate critical information. For all cases it was seen that three dimensional scans were more efficient in providing the orientation, within a short time. CONCLUSION: By dual source multidedector tomography systems trauma patients may be evaluated by multiplanary and three dimensionally reconstructed images. When used correctly...

Molecular Mechanisms Underlying Adaptation to PAHs in Fundulus heteroclitus

Clark, Bryan
Fonte: Universidade Duke Publicador: Universidade Duke
Tipo: Dissertação
Publicado em //2010
Relevância na Pesquisa
36.11%

Chronic exposure to toxicant mixtures is a serious threat to environmental and human health. It is especially important to understand the effects of these exposures for contaminants, such as polycyclic aromatic hydrocarbons (PAHs), which are toxic, ubiquitous, and increasingly prevalent. Furthermore, estuarine systems are of particular concern, as they are highly impacted by a wide variety of pollutants; fish there are often exposed to some of the highest levels of contaminants of any vertebrate populations, along with other stressors such as fluctuations in water level, dissolved oxygen, and temperature. A population of Fundulus heteroclitus (the Atlantic killifish or mummichog, hereafter referred to as killifish) inhabits a Superfund site heavily contaminated with a mixture of PAHs from former creosote operations; they have developed resistance to the acute toxicity and teratogenic effects caused by the mixture of PAHs in sediment from the site. The primary goal of this dissertation was to better understand the mechanism(s) by which Elizabeth River killifish resist the developmental toxicity of a complex mixture of PAHs and to investigate the tradeoffs associated with this resistance. Because the aryl hydrocarbon receptor (AHR) pathway plays an important role in mediating the effects of PAHs...

Mental and social health during and after acute emergencies: emerging consensus?

van Ommeren,Mark; Saxena,Shekhar; Saraceno,Benedetto
Fonte: World Health Organization Publicador: World Health Organization
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2005 EN
Relevância na Pesquisa
35.79%
Mental health care programmes during and after acute emergencies in resource-poor countries have been considered controversial. There is no agreement on the public health value of the post-traumatic stress disorder concept and no agreement on the appropriateness of vertical (separate) trauma-focused services. A range of social and mental health intervention strategies and principles seem, however, to have the broad support of expert opinion. Despite continuing debate, there is emerging agreement on what entails good public health practice in respect of mental health. In terms of early interventions, this agreement is exemplified by the recent inclusion of a "mental and social aspects of health" standard in the Sphere handbook's revision on minimal standards in disaster response. This affirmation of emerging agreement is important and should give clear messages to health planners.