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Assessment of flow in perforating arteries during intracranial aneurysm surgery using intraoperative near-infrared indocyanine green videoangiography

OLIVEIRA, Jean G. de; BECK, Juergen; SEIFERT, Volker; TEIXEIRA, Manoel J.; RAABE, Andreas
Fonte: LIPPINCOTT WILLIAMS & WILKINS Publicador: LIPPINCOTT WILLIAMS & WILKINS
Tipo: Artigo de Revista Científica
ENG
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OBJECTIVE: Perforating arteries are commonly involved during the surgical dissection and clipping of intracranial aneurysms. Occlusion of perforating arteries is responsible for ischemic infarction and poor outcome. The goal of this study is to describe the usefulness of near-infrared indocyanine green videoangiography (ICGA) for the intraoperative assessment of blood flow in perforating arteries that are visible in the surgical field during clipping of intracranial aneurysms. In addition, we analyzed the incidence of perforating vessels involved during the aneurysm surgery and the incidence of ischemic infarct caused by compromised small arteries. METHODS: Sixty patients with 64 aneurysms were surgically treated and prospectively included in this study. Intraoperative ICGA was performed using a surgical microscope (Carl Zeiss Co., Oberkochen, Germany) with integrated ICGA technology. The presence and involvement of perforating arteries were analyzed in the microsurgical field during surgical dissection and clip application. Assessment of vascular patency after clipping was also investigated. Only those small arteries that were not visible on preoperative digital subtraction angiography were considered for analysis. RESULTS: The ICGA was able to visualize flow in all patients in whom perforating vessels were found in the microscope field. Among 36 patients whose perforating vessels were visible on ICGA...

Uridine adenosine tetraphosphate-induced contraction is increased in renal but not pulmonary arteries from DOCA-salt hypertensive rats

MATSUMOTO, Takayuki; TOSTES, Rita C.; WEBB, R. Clinton
Fonte: AMER PHYSIOLOGICAL SOC Publicador: AMER PHYSIOLOGICAL SOC
Tipo: Artigo de Revista Científica
ENG
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Matsumoto T, Tostes RC, Webb RC. Uridine adenosine tetraphosphate-induced contraction is increased in renal but not pulmonary arteries from DOCA-salt hypertensive rats. Am J Physiol Heart Circ Physiol 301: H409-H417, 2011. First published May 6, 2011; doi:10.1152/ajpheart.00084.2011.-Uridine adenosine tetraphosphate (Up(4)A) was reported as a novel endothelium-derived contracting factor. Up(4)A contains both purine and pyrimidine moieties, which activate purinergic (P2)X and P2Y receptors. However, alterations in the vasoconstrictor responses to Up(4)A in hypertensive states remain unclear. The present study examined the effects of Up(4)A on contraction of isolated renal arteries (RA) and pulmonary arteries (PA) from DOCA-salt rats using isometric tension recording. RA from DOCA-salt rats exhibited increased contraction to Up(4)A versus arteries from control uninephrectomized rats in the absence and presence of N(G)-nitro-L-arginine (nitric oxide synthase inhibitor). On the other hand, the Up(4)A-induced contraction in PA was similar between the two groups. Up(4)A-induced contraction was inhibited by suramin (nonselective P2 antagonist) but not by diinosine pentaphosphate pentasodium salt hydrate (Ip5I; P2X(1) antagonist) in RA from both groups. Furthermore...

Impaired beta-adrenoceptor-induced relaxation in small mesenteric arteries from DOCA-salt hypertensive rats is due to reduced K-Ca channel activity

Matsumoto, Takayuki; Szasz, Theodora; Tostes, Rita C.; Webb, R. Clinton
Fonte: ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD; LONDON Publicador: ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD; LONDON
Tipo: Artigo de Revista Científica
ENG
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beta-Adrenoceptor (beta-AR)-mediated relaxation plays an important role in the regulation of vascular tone. beta-AR-mediated vascular relaxation is reduced in various disease states and aging. We hypothesized that beta-AR-mediated vasodilatation is impaired in DOCA-salt hypertension due to alterations in the cAMP pathway. beta-AR-mediated relaxation was determined in small mesenteric arteries from DOCA-salt hypertensive and control uninephrectomized (Uni) rats. To exclude nitric oxide (NO) and cyclooxygenase (COX) pathways, relaxation responses were determined in the presence of L-NNA and indomethacin, NO synthase inhibitor and COX inhibitors, respectively. Isoprenaline (ISO)-induced relaxation was reduced in arteries from DOCA-salt compared to Uni rats. Protein kinase A (PKA) inhibitors (H89 or Rp-cAMPS) or adenylyl cyclase inhibitor (SQ22536) did not abolish the difference in ISO-induced relaxation between the groups. Forskolin (adenylyl cyclase activator)-induced relaxation was similar between the groups. The inhibition of IKCa/SKCa channels (TRAM-34 plus UCL1684) or BKCa channels (iberiotoxin) reduced ISO-induced relaxation only in Uni rats and abolished the relaxation differences between the groups. The expression of SKCa channel was decreased in DOCA-salt arteries. The expression of BKCa channel a subunit was increased whereas the expression of BKCa channel p subunit was decreased in DOCA-salt arteries. The expression of receptor for activated C kinase 1 (RACK1)...

Efeito do treinamento físico no remodelamento de grandes artérias em ratos normotensos e hipertensos.; Effect of exercise training in the remodeling of large arteries in spontaneously hypertensive and normotensive rats.

Jordão, Maria Tereza
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 11/09/2008 PT
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Investigamos os efeitos do treinamento físico (T) aeróbio sobre o possível remodelamento de grandes artérias de animais hipertensos (SHR) e normotensos (WKY). Os animais foram submetidos à T em esteira (50-60% da capacidade máxima, 1h/dia, 5dias/semana) ou mantidos sedentários (S) por 3 meses. Ao final dos protocolos, foram submetidos à canulação crônica para registros hemodinâmicos basais. A seguir foram anestesiados e perfundidos com salina e PFA 4% para análise histológica e com solução Karnovski para microscopia eletrônica de transmissão (MET). A aorta torácica e abdominal e as artérias carótida, renal e femoral foram retiradas e processadas para a técnica de Weigert/Hematoxilina e MET. Na análise morfométrica foram determinados os seguintes parâmetros: DI, DE, espessura de parede, razão média/luz e AST de todos os segmentos arteriais, enquanto que na análise estereológica quantificou-se a densidade numérica (QA), a densidade volume (VV) e a densidade de área (SV) do núcleo do músculo liso vascular e do componente elástico (total, lamelar e fibrilar). Nos SHRS (vs WHYS) a PAM e FC basais apresentavam-se elevados (172±1 mmHg e 386±9 bpm, respectivamente). TF foi igualmente eficaz em aumentar o ganho de capacidade física em ambos os grupos (+264±12 e +279±33 m)...

Avaliação do fluxo sanguíneo em artérias perfurantes durante a cirurgia de aneurismas  intracranianos através da video-angiografia intra-operatória utilizando indocianina verde; Assessment of blood flow in perforating arteries during intracranial aneurysm surgery with intraoperative videoangiography using indocyanine green

Oliveira, Jean Gonçalves de
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 22/01/2010 PT
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36.83%
Introdução. As artérias perfurantes comumente são evidenciadas durante a dissecção microcirúrgica para clipagem de aneurismas intracranianos. A oclusão de artérias perfurantes pode ser responsável por infarto encefálico isquêmico e resultados clínicos indesejáveis. O presente estudo objetiva descrever a utilidade da vídeo-angiografia intra-operatória com indocianina verde (VAIICG) na avaliação do fluxo sanguíneo em artérias perfurantes visibilizadas no campo microcirúrgico, durante a clipagem de aneurismas intracranianos. Secundariamente, foi analisada a incidência de artérias perfurantes envolvidas durante a cirurgia de aneurismas intracranianos, e a ocorrência de infarto encefálico isquêmico causado pelo comprometimento das artérias perfurantes. Método. Sessenta pacientes, com 64 aneurismas intracranianos foram tratados cirurgicamente, e prospectivamente incluídos neste estudo. A VAIICG intra-operatória foi realizada com o uso de microscópio neurocirúrgico (Carl Zeiss Co. Oberkochen, Germany) com a tecnologia VAIICG integrada. A presença e o envolvimento de artérias perfurantes foram analisados no campo microcirúrgico durante a dissecção cirúrgica, e durante a clipagem do aneurisma. A patência vascular após a clipagem também foi investigada. Apenas artérias pequenas que não foram visibilizadas nas imagens pré-operatórias de angiografia digital com subtração (ADS) foram consideradas para análise. Resultados. A VAIICG permitiu a visibilização do fluxo sanguíneo em todos os casos que apresentaram artérias perfurantes no campo microcirúrgico. Dentre 36 casos cujas artérias perfurantes estavam visíveis à VAIICG...

Visibilização de artérias coronárias epicárdicas em imagens ecocardiográficas tridimensionais com contraste de microbolhas; Visualization of the epicardial coronary arteries in microbubble contrasted tri-dimensional echocardiographic images

Lage, Danilo Meneses
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Tese de Doutorado Formato: application/pdf
Publicado em 01/10/2010 PT
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36.69%
Com os avanços tecnológicos das últimas décadas, a ecocardiografia surgiu como uma alternativa de diagnóstico por imagem de relativo baixo custo, que não faz uso de energia ionizante ou radioativa. Recentemente, o advento dos agentes de contraste por microbolhas e dos transdutores matriciais tornou possível a visualização tridimensional da anatomia das artérias coronárias. Neste projeto, é proposta a avaliação de métodos de segmentação capazes de visibilizar as artérias coronárias epicárdicas em Imagens de ecocardiografias tridimensionais com contraste de microbolhas. Esse é o primeiro passo para o desenvolvimento de ferramentas computacionais eficazes e eficientes na assistência não invasiva ao acompanhamento do quadro clínico de pacientes, do diagnóstico ao pós-operatório. Propõe-se, uma metodologia que facilite o acesso às coronárias a partir de imagens de ecocardiografia tridimensionais com aplicação de contraste por microbolhas. Dentre as metodologias estudadas, as técnicas baseadas na teoria Fuzzy Connectedness (FC) foram identificadas como as mais promissoras. Estudou-se, portanto, seis abordagens baseadas nessa teoria, três delas são descritas na literatura (Generalized FC GFC; Relative FC RFC; Dynamic Weighted FC DyWFC) e três proposições originais (Area of Search FC ASFC; Ultrasound-k FC USFC; Guided FC GuFC). Para avaliar a acurácia desses algoritmos...

Systematization, description and territory of the middle and rostral cerebral arteries in broad-snouted caimans (Caiman latirostris)

Almeida, Lygia Maria de; Campos, Rui
Fonte: Universidade Federal do Rio Grande do Sul Publicador: Universidade Federal do Rio Grande do Sul
Tipo: Artigo de Revista Científica Formato: application/pdf
ENG
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36.69%
Background: Information on the arterial vascularization of the broad-snouted caimans’ brain (Caiman latirostris), a specie from the Brazilian fauna, is inexistent and the literature consulted yielded only one description about the development of embryonic circulation and post-birth cerebrovascular alterations in the brain of three caymans. The objective of this study was to describe and systematize the cerebral arterial vascularization of this reptile, by providing a standard irrigation model with its major variations, in addition to determining its territorial vascular areas. Materials, Methods & Results: Thirty heads of male broad-snouted caimans (Caiman latirostris), with the neck segment, were used in the study. Additionally, two whole female and male specimens, with approximately 3 years of age and weighing between 8 to 10 Kg were also used. The animals were sacrificed according to routine slaughterhouse norms. The heads were sectioned at the third cervical vertebra level and the azygos carotid artery was cannulated. The arterial system was washed with 0.9% saline solution and filled with red-colored latex. The pieces were fixed in formaldehyde and the encephalon removed through a window made in the cranial vault, which was followed by removal of the dura mater and dissection of the arteries. The internal carotid arteries displayed an intercarotic anastomosis in the samples examined...

A systematic study of the brain base arteries in the rabbit (Oryctolagus cuniculus); Sistematização das artérias da base do encéfalo e suas fontes de suprimento sanguíneo em coelho da raça Nova Zelândia (Oryctolagus cuniculus)

Souza, Fernanda de; Campos, Rui
Fonte: Universidade Federal do Rio Grande do Sul Publicador: Universidade Federal do Rio Grande do Sul
Tipo: Artigo de Revista Científica Formato: application/pdf
ENG
Relevância na Pesquisa
36.74%
The brains of 30 New Zealand rabbits (Oryctolagus cuniculus) were injected with red stained latex. The arteries of the ventral surface of the brain were systematized on the right (R) and on the left (L) side with the respective percentage of appearance: the aortic arch emitted the braquicephalic trunk and the left subclavian artery (83.3%); or the braquicephalic trunk, the left common carotid artery and the left subclavian artery (16.7%). The braquicephalic trunk emitted the right and the left common carotid arteries and the right subclavian artery (83.3%); or the right common carotid artery and the right subclavian artery (16.7%). The common carotid arteries were divided into external and internal carotid arteries (96.7% on the R, 100% on the L.). The internal carotid artery to the R was present (96.7%) and absent (3.3%), and to the L, was present (100%). The rostral choroidal artery to the R was collateral branch of the rostral branch of the internal carotid artery (83.3%), collateral branch of caudal branch of the internal carotid artery (16.7%), and to the L was collateral branch of the rostral branch of the internal carotid artery (93.3%), collateral branch of the caudal branch of the internal carotid artery (6.7%). The middle cerebral artery to the R and to the L was single (80%) and double (20%). The rostral cerebral artery to the R had middle caliber (90%)...

Testicular arteries systematization based on different levels of scrotal configuration in caprines

Almeida, Mônica Marco de; Assis Neto, Antônio Chaves de; Penno, Alexandra Klindline; Conde Júnior, Airton Mendes; Menezes, Danilo Jose Ayres de; Pereira, Gabriel Ribas; Azevêdo, Laurita Martins de; Carvalho, Maria Acelina Martins de
Fonte: Universidade Federal de Santa Maria (UFSM) Publicador: Universidade Federal de Santa Maria (UFSM)
Tipo: Artigo de Revista Científica Formato: 1308-1312
ENG
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36.69%
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); O objetivo deste trabalho foi analisar a distribuição dos vasos arteriais nos testículos em caprinos com diferentes graus de divisão escrotal. A configuração escrotal foi classificada da seguinte forma: Grupo I: constituído por caprinos com escroto único, Grupo II: com escroto separado até a metade do testículo e Grupo III: com separação escrotal estendendo-se além da metade do testículos. As artérias foram injetadas e coradas com solução de acetado de vinil, sendo os orgãos (30 pares) submetidos à corrossão para obtenção dos moldes vasculares. As artérias testiculares emergem da aorta abdominal, com trajeto retilíneo, atravessam o canal inguinal, apresentam-se espiraladas e envolvidas parcialmente pelo plexo pampiniforme. Próximo à extremidade caudada do testículo, dividem-se mais freqüentemente nos ramos cranial e caudal, os quais emitem vasos colaterais, de onde emergem ramos penetrantes. Os testículos dos animais com nível intermediário de divisão escrotal (Grupo II) apresentam menor quantidade destes ramos, sendo os quadrantes mais povoados o ventrolateral e o dorsolateral. Conclui-se que a origem, o trajeto e a distribuição das artérias testiculares não apresentam variações relacionadas ao grau de divisão escrotal em caprinos.; The objective of this study was to describe the distribution of testicular arterial vessels in caprines with different degrees of scrotal division. Scrotal configurations were classified as follows; Group I: scrotum without bipartition; Group II: scrotum showing a ventral division until the middle of the testis; and...

Value of ultrasonographic contrast in duplex scanning of leg arteries - Comparison with conventional duplex scanning and arteriography

Giannini, M.; Rollo, H. A.; Yoshida, W. B.; Lastoria, S.; Moura, R.; Maffei, FHD
Fonte: Edizioni Minerva Medica Publicador: Edizioni Minerva Medica
Tipo: Artigo de Revista Científica Formato: 263-269
ENG
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Aim. Duplex scanning has been used in the evaluation of the aorta and proximal arteries of the lower extremities, but has limitations in evaluating the arteries of the leg. The utilization of ultrasonographic contrast (USC) may be helpful in improving the quality of the image in these arteries. The objective of the present study was to verify whether the USC increases the diagnostic accuracy of patency of the leg arteries and if it diminishes the time needed to perform duplex scanning.Methods. Twenty patients with critical ischemia (20 lower extremities) were examined by standard duplex scanning, duplex scanning with contrast and digital subtraction arteriography (DSA). The 3 arteries of the leg were divided into 3 segments, for a total of 9 segments per limb. Each segment was evaluated for patency in order to compare the 3 diagnostic methods. Comparison was made between standard duplex scanning and duplex scanning with contrast in terms of quality of the color-coded Doppler signal and of the spectral curve, and also of the time to perform the exams.Results. Duplex scanning with contrast was similar to arteriography in relation to patency diagnosis (p>0.3) and even superior in some of the segments. Standard duplex scanning was inferior to arteriography and to duplex scanning with contrast (p<0.001). There were improvements of 70% in intensity of the color-coded Doppler signal and 76% in the spectral curve after the utilization of contrast. The time necessary to perform the examinations was 23.7 minutes for standard duplex scanning and 16.9 minutes for duplex scanning with contrast (p<0.001).Conclusion. The use of ultrasonographic contrast increased the accuracy of the diagnosis of patency of leg arteries and diminished the time necessary for the execution of duplex scanning.

Study on Cranial and Caudal Mesenteric Arteries in Opossum (Didelphis albiventris)

de Carvalho Pinto e Silva, Jose Ricardo; Fernandes Boaro Martins, Marcia Regina; Guazzelli Filho, Joffre
Fonte: Soc Chilena Anatomia Publicador: Soc Chilena Anatomia
Tipo: Artigo de Revista Científica Formato: 635-637
ENG
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The objective of this study is to describe the cranial and caudal mesenteric arteries in 10 opossuns after Neoprene latex injection. The cranial mesenteric artery arises from the abdominal aorta, caudally to the celiac trunk, originating the caudal duodenal pancreatic artery, middle and right colic, jejunal and ileocecocolic arteries. The caudal mesenteric artery arises from the aorta, cranially to the external iliac arteries, originating the cranial rectal and left colic arteries.

Immunohistochemical identification of plasma protein deposits in the wall of lenticulostriate arteries in patients with long-standing hypertension, with and without lipohyalinosis

Andrade,Magda Rocha; Pittella,José Eymard Homem
Fonte: Academia Brasileira de Neurologia - ABNEURO Publicador: Academia Brasileira de Neurologia - ABNEURO
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/03/2009 EN
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PURPOSE: To investigate, through an immunohistochemical method, whether there is deposition of plasma proteins in the wall of lenticulostriate, cortical and leptomeningeal arteries of hypertensive patients, with and without lipohyalinosis. METHOD: Forty patients with essential hypertension were selected at random, 20 with lipohyalinosis in the lenticulostriate arteries (HH group) and 20 without lipohyalinosis (H group), matched with 20 normotensive controls (C group). RESULTS: Plasma protein deposits were identified in eight patients (40%) in the C group, in 15 patients (75%) in the H group, and in all 20 patients (100%) in the HH group, the difference being significant for the H group and highly significant for the HH group, as compared with the C group. In all groups, the distribution of plasma protein deposits, subendothelial in normal arteries, and diffuse, irregular in the wall of arteries with lipohyalinosis, was more frequent in the lenticulostriate arteries of the putamen. CONCLUSION: Deposition of plasma proteins in the lenticulostriate arteries seems to be relatively frequent in normotensive individuals, starting in middle age. Such process appears to be intensified by hypertension, especially in individuals with lipohyalinosis.

Correlation between total nitrite/nitrate concentrations and monoamine oxidase (types A and B) and semicarbazide-sensitive amine oxidase enzymatic activities in human mesenteric arteries from non-diabetic and type 2 diabetic patients

Nunes,S.F.; Figueiredo,I.V.; Pereira,J.S.; Lopes,M.C.; Caramona,M.M.
Fonte: Associação Brasileira de Divulgação Científica Publicador: Associação Brasileira de Divulgação Científica
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2012 EN
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The aim of this study was to determine the correlation between total nitrite/nitrate concentrations (NOx) and the kinetic parameters of monoamine oxidase enzymes (MAO-A and MAO-B) and semicarbazide-sensitive amine oxidase (SSAO) in human mesenteric arteries. Arteries were from non-diabetic and type 2 diabetic patients with sigmoid or rectum carcinoma for whom surgery was the first option and who were not exposed to neo-adjuvant therapy. Segments of human inferior mesenteric arteries from non-diabetic (61.1 ± 8.9 years old, 7 males and 5 females, N = 12) and type 2 diabetic patients (65.8 ± 6.2 years old, 8 males and 4 females, N = 12) were used to determine NOx concentrations and the kinetic parameters of MAO-A, MAO-B and SSAO by the Griess reaction and by radiochemical assay, respectively. The NOx concentrations in arteries from diabetic patients did not differ significantly from those of the non-diabetic group (10.28 ± 4.61 vs 10.71 ± 4.32 nmol/mg protein, respectively). In the non-diabetic group, there was a positive correlation between NOx concentrations and MAO-B parameters: Km (r = 0.612, P = 0.034) and Vmax (r = 0.593, P = 0.042), and a negative correlation with the SSAO parameters: Km (r = -0.625, P = 0.029) and Vmax (r = -0.754...

Early outcomes of laparoscopic donor nephrectomy with multiple renal arteries

Meyer,Fernando; Nichele,Sandro A.; Adamy,Ari; Santos,Luiz Sergio; Machado,Christiano
Fonte: Sociedade Brasileira de Urologia Publicador: Sociedade Brasileira de Urologia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/08/2012 EN
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PURPOSE: We evaluated our experience with laparoscopic donor nephrectomy in patients with multiple renal arteries, comparing operative outcomes and early graft function with patients with a single renal artery. MATERIALS AND METHODS: From January 2003 to February 2009, 130 patients underwent laparoscopic donor nephrectomy at our institution, 108 (83%) with a single renal artery and 22 (17%) with multiple arteries. Donor and recipient outcomes for single artery and multiple arteries allografts were compared. RESULTS: The LDN operative time was similar between the single artery and multiple arteries groups (162 vs 163 min, respectively, p = 0.87). Allografts with multiple arteries had significantly longer warm ischemia time (3.9 vs 4.9 min, p = 0.05) and cold ischemia time (72 vs 94 min, p < 0.001) than those with single artery. The conversion rate was similar between single and multiple arteries groups (6% vs 4.5%, respectively, p = 0.7). Multiple arteries grafts had a non statistically significant higher rate of poor graft function when compared to single artery grafts (23% vs 12%, respectively, p = 0.18). Five patients in the single artery group (4.6%) and one patient in the multiple arteries group (4.5%) needed dialysis during the first postoperative week. Overall...

Surgical complications after renal transplantation in grafts with multiple arteries

Mazzucchi,Eduardo; Souza,Auro A.; Nahas,Willian C.; Antonopoulos,Ioannis M.; Piovesan,Affonso C.; Arap,Sami
Fonte: Sociedade Brasileira de Urologia Publicador: Sociedade Brasileira de Urologia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/04/2005 EN
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INTRODUCTION: Renal transplantation with multiple arteries appears, in literature, associated to a major index of surgical complications. This study compared the surgical complications and short-term outcome renal transplants with multiple arteries and single artery grafts. MATERIALS AND METHODS: The data of 64 renal transplants with multiple arteries performed between January 1995 and December 1999 were compared to the ones of 292 transplants with single renal artery. The aspects analyzed were number of arteries of the graft, donor type, vascular reconstruction technique, the occurrence of surgical complications, the incidence of delayed graft function, graft function 1 month after transplantation, graft loss and the patients' deaths. RESULTS: The incidence of surgical complications in grafts with multiple arteries and single renal artery was respectively: vascular - 3.1% and 3.1%; urological - 6.3% and 2.7% and other surgical complications - 15.6% and 10.6%, respectively. The incidence of lymphoceles was 3.1% in grafts with a single artery and 12.5% in grafts with more than 1 artery (p = 0.0015). The incidence of delayed graft function in grafts with multiple arteries and with a single renal artery was respectively 35.1 and 29.1% (p = 0.295). Mean serum creatinine at the 30th postoperative day was 2.46 and 1.81 in grafts with multiple and with 1 artery...

A systematic study of the brain base arteries in the rabbit (Oryctolagus cuniculus)

Souza,Fernanda de; Campos,Rui
Fonte: Colégio Brasileiro de Patologia Animal - CBPA; Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA) Publicador: Colégio Brasileiro de Patologia Animal - CBPA; Empresa Brasileira de Pesquisa Agropecuária (EMBRAPA)
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/2013 EN
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36.74%
The brains of 30 New Zealand rabbits (Oryctolagus cuniculus) were injected with red stained latex. The arteries of the ventral surface of the brain were systematized on the right (R) and on the left (L) side with the respective percentage of appearance: the aortic arch emitted the braquicephalic trunk and the left subclavian artery (83.3%); or the braquicephalic trunk, the left common carotid artery and the left subclavian artery (16.7%). The braquicephalic trunk emitted the right and the left common carotid arteries and the right subclavian artery (83.3%); or the right common carotid artery and the right subclavian artery (16.7%). The common carotid arteries were divided into external and internal carotid arteries (96.7% on the R, 100% on the L.). The internal carotid artery to the R was present (96.7%) and absent (3.3%), and to the L, was present (100%). The rostral choroidal artery to the R was collateral branch of the rostral branch of the internal carotid artery (83.3%), collateral branch of caudal branch of the internal carotid artery (16.7%), and to the L was collateral branch of the rostral branch of the internal carotid artery (93.3%), collateral branch of the caudal branch of the internal carotid artery (6.7%). The middle cerebral artery to the R and to the L was single (80%) and double (20%). The rostral cerebral artery to the R had middle caliber (90%)...

Statins and selective inhibition of Rho kinase protect small conductance calcium-activated potassium channel function (KCa2.3) in cerebral arteries

McNeish, Alister J.; Jiménez Altayó, Francesc; Cottrell, Graeme S.; Garland, Christopher J.
Fonte: Universidade Autônoma de Barcelona Publicador: Universidade Autônoma de Barcelona
Tipo: Artigo de Revista Científica Formato: application/pdf
Publicado em //2012 ENG
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Background: In rat middle cerebral and mesenteric arteries the KCa2.3 component of endothelium-dependent hyperpolarization (EDH) is lost following stimulation of thromboxane (TP) receptors, an effect that may contribute to the endothelial dysfunction associated with cardiovascular disease. In cerebral arteries, KCa2.3 loss is associated with NO synthase inhibition, but is restored if TP receptors are blocked. The Rho/Rho kinase pathway is central for TP signalling and statins indirectly inhibit this pathway. The possibility that Rho kinase inhibition and statins sustain KCa2.3 hyperpolarization was investigated in rat middle cerebral arteries (MCA). Methods: MCAs were mounted in a wire myograph. The PAR2 agonist, SLIGRL was used to stimulate EDH responses, assessed by simultaneous measurement of smooth muscle membrane potential and tension. TP expression was assessed with rt-PCR and immunofluorescence. Results: Immunofluorescence detected TP in the endothelial cell layer of MCA. Vasoconstriction to the TP agonist, U46619 was reduced by Rho kinase inhibition. TP receptor stimulation lead to loss of KCa2.3 mediated hyperpolarization, an effect that was reversed by Rho kinase inhibitors or simvastatin. KCa2.3 activity was lost in L-NAME-treated arteries...

Artérias da base do encéfalo de eqüinos. Sistema occipito-basilar; Encephalon basis' arteries in horses. Occipito-basilar system

Campos, Aglai; Prada, Irvênia Luiza de Santis; Santos Junior, Ivaldo dos; Santos, Djenane dos
Fonte: Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia Publicador: Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; ; ; Formato: application/pdf
Publicado em 01/01/2003 POR
Relevância na Pesquisa
36.77%
Foram dissecadas 24 peças correspondentes a eqüinos da raça Puro Sangue Inglês, injetadas com Neoprene latex 650 corado e fixadas em formol a 25%. As artérias da base do encéfalo estudadas estão na dependência de duas grandes fontes representadas, uma delas pelas artérias occipitais direita e esquerda (sistema occipito-basilar) e, a outra, pelas artérias carótidas internas direita e esquerda (sistema carótico). A artéria basilar resulta da convergência das artérias occipitais direita e esquerda (95,8%), na região limítrofe entre medula espinhal e bulbo e termina dividindo-se, em correspondência à porção caudal dos pedúnculos cerebrais - com a ocorrência de variável número de tractos anastomóticos dispostos em rede - em dois bem definidos ramos terminais, assim considerados até a origem, em cada antímero, da artéria cerebral caudal. Observam-se ainda tractos anastomóticos relacionados à origem (37,5%) e ao percurso (20,8%) da artéria basilar, durante o qual ela emite numerosos colaterais, em ambos os antímeros, dos quais destacam-se as artérias cerebelar caudal (100%), carótico-basilar (54,2%), labiríntica (12,5% diretamente ou 62,5% indiretamente, como ramo da artéria cerebelar caudal) e artéria cerebelar rostral (100%). Os colaterais da artéria basilar com ela estabelecem...

Contribution to the study of the origin and ramification of the cranial and caudal mesenteric arteries in Zebu foetuses; Contribuição ao estudo da origem e ramificação das artérias mesentéricas cranial e caudal, em fetos de bovinos azebuados

Silva, Frederico Ozanam Carneiro e; Peduti Neto, José; Bombonato, Pedro Primo
Fonte: Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia Publicador: Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; Formato: application/pdf
Publicado em 15/03/1985 POR
Relevância na Pesquisa
36.74%
Foram estudados 30 fetos de bovinos azebuados (15 machose 15 fêmeas), injetados com solução de Neoprene latex 450 e fixados em solução de formol a 10,0%, tendo-se verificado que a artéria mesentérica cranial origina-se da artéria aorta abdominal, caudalmente à artéria celíaca ou em tronco comum com esta, emitindo a ses peculiares. Para a artéria mesentérica caudal notou-se sua origem sempre da artéria aorta abdominal, próximo aos seus ramos terminais, emitindo comumente a artéria cólica esquerda cranialmente e continuando-se como artéria retal cranial.; Reminding that the anatomical data in bovines usually regard european breeds (Bos taurus) we preposed to study now the pattern of the mesenteric arteries in zebu cattle (Bos indicus). Thuswe have dissected 30 foetuses (15 males and 15 females) which were injected with Neoprene latex 450 and fixed in formol solution(10%). The results obtained permit the following conclusions: 1) the cranial mesenteric artery arises from the abdominal aorta artery just after the colic artery or in common trunk with this and give up the following branches: adrenal artery, diaphagmatic artery, artery to the adjacent connective tissue, pancreatic artery, caudal pancreatic duodenal artery...

Contribuição ao estudo da ramificação das artérias mesentéricas cranial e caudal em saguis (Callithrix jacchus); Contribution to the study o f the branching of the cranial and caudal mesenterics arteries in marmosets (Callithrix jacchus)

Albuquerque, José Fernando Gomes de; Fernandes Filho, Antonio; Borelli, Vicente
Fonte: Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia Publicador: Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; Formato: application/pdf
Publicado em 15/03/1976 POR
Relevância na Pesquisa
36.83%
Mediante dissecção, a origem, ramificação e destino das aa. mesentéricas cranial e caudal de 20 saguis (10 machos e 10 fêmeas), previamente injetados com, Neoprene Latex “650”, chegou-se às seguintes conclusões: 1) Em 10 preparações (50,0% ± 11,2), a a. mesentérica cranial fornece, inicialmente, a a. cólica média seguida de tronco de origem das aa. jejunais e ileocecocólica. 2) Em 5 casos (25,0% ± 6,7), a a. mesentérica cranial cede apenas as aa. jejunais e a a. ileocecocólica. 3) Em 2 peças (10,0% ± 6,7), a a. mesentérica cranial dá origem somente às aa. jejunais e ileocecal. 4) Em 2 animais (10,0% ± 6,7), da a. mesentérica cranial emergem, por ordem, as aa. jejunais e tronco comum constituído pelas aa. cólica média e ileocecocólica. 5) Em 1 observação (5,0% ± 4,9), da. a. mesentérica cranial partem, primeiramente, a a. cólica média e a seguir, dois troncos formados, respectivamente, pelas aa. cecal e cólica direita e pelas aa. jejunais e ileal. 6) Em todas as dissecções (100,0%), da a. mesentérica caudal nascem as aa. cólica esquerda e hemorroidal cranial.; The origin, branching and distribution of the cranial and caudal mesenterics arteries were studied in 20 marmosets (Callithrix jacchus)...