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Implications of Extending the ADHD Age-of-Onset Criterion to Age 12: Results from a Prospectively Studied Birth Cohort

POLANCZYK, Guilherme; CASPI, Avshalom; HOUTS, Renate; KOLLINS, Scott H.; ROHDE, Luis Augusto; MOFFITT, Terrie E.
Fonte: LIPPINCOTT WILLIAMS & WILKINS Publicador: LIPPINCOTT WILLIAMS & WILKINS
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
36.06%
Objective: To evaluate whether including children with onset of symptoms between ages 7 and 12 years in the ADHD diagnostic category would: (a) increase the prevalence of the disorder at age 12, and (b) change the clinical and cognitive features, impairment profile, and risk factors for ADHD compared with findings in the literature based on the DSM-IV definition of the disorder. Method: A birth cohort of 2,232 British children was prospectively evaluated at ages 7 and 12 years for ADHD using information from mothers and teachers. The prevalence of diagnosed ADHD at age 12 was evaluated with and without the inclusion of individuals who met DSM-IV age-of-onset criterion through mothers` or teachers` reports of symptoms at age 7. Children with onset of ADHD symptoms before versus after age 7 were compared on their clinical and cognitive features, impairment profile, and risk factors for ADHD. Results: Extending the age-of-onset criterion to age 12 resulted in a negligible increase in ADHD prevalence by age 12 years of 0.1%. Children who first manifested ADHD symptoms between ages 7 and 12 did not present correlates or risk factors that were significantly different from children who manifested symptoms before age 7. Conclusions: Results from this prospective birth cohort might suggest that adults who are able to report symptom onset by age 12 also had symptoms by age 7...

Fatores sociodemográficos e proporção de crianças que deixam de ter baixo peso para idade, em programa governamental de distribuição de leite fortificado, nas idades de 6 a 23 meses; Sociodemographic factors and proportion of children who stop having low weight for age in program government distribution of fortified milk in ages 6-23 months.

Ortelan, Naiá
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 12/06/2013 PT
Relevância na Pesquisa
36.06%
INTRODUÇÃO: É importante que programas de intervenção nutricional sejam avaliados. Estudo anterior mostrou que o Projeto Vivaleite, programa de distribuição de leite fortificado no Estado de São Paulo, é efetivo quando se comparam as médias dos escores z do indicador de peso para idade (P/I) de crianças ainda fora do programa com as crianças no programa, na faixa etária de 6 a 23 meses, independentemente de variáveis sociodemográficas. OBJETIVO: Estudar a associação entre fatores sociodemográficos e a proporção de crianças que deixam de ter baixo P/I, nas idades de 6 a 23 meses, durante sua participação, no período de janeiro/2003 a setembro/2008, em programa governamental de distribuição de leite fortificado. MÉTODOS: Estudo de coorte prospectiva com dados de 327 crianças residentes no interior do Estado de São Paulo que ingressaram, aos seis meses de idade, com baixo P/I (escore z P/I <-2) no Vivaleite. Foram selecionadas as seguintes variáveis: a) Resposta: baixo P/I, indicadora da situação de baixo P/I (escore z P/I < -2) apresentado pela criança durante as pesagens após a criança ingressar no programa (dicotômica, sim=0|não=1); b) Explanatórias: aleitamento materno (não recebe=0|recebe=1)...

Evolução do desenvolvimento motor e cognitivo de pré-escolares nascidos pré-termo de muito baixo peso egressos do método canguru; Very low weight preterm infants cognitive and motor development at preschool age that were former patients FROM THE KANGAROO METHOD

Gonçalves, Claudia Maria Ribeiro Martins
Fonte: Biblioteca Digitais de Teses e Dissertações da USP Publicador: Biblioteca Digitais de Teses e Dissertações da USP
Tipo: Dissertação de Mestrado Formato: application/pdf
Publicado em 18/03/2014 PT
Relevância na Pesquisa
36.07%
INTRODUÇÃO: O Método Canguru é um tipo de assistência neonatal que consiste no contato precoce pele a pele entre a mãe e o recém-nascido de baixo peso, de forma crescente e pelo tempo que ambos entenderem ser prazeroso e suficiente, permitindo dessa forma, uma maior participação dos pais no cuidado a seu recém-nascido, acompanhado de suporte assistencial, por uma equipe de saúde treinada adequadamente. Tem como premissa a interação dinâmica e continua entre fatores biomédicos e ambientais. OBJETIVO: Descrever a evolução do desenvolvimento motor e cognitivo de pré-escolares de muito baixo peso egressos do Método Canguru, que receberam leite humano durante o período de internação. MÉTODOS: Foram estudadas 54 crianças prematuras, no período de Janeiro de 2004 a Janeiro de 2011 que participaram do Método Canguru e acompanhadas no Ambulatório de Seguimento, até a idade pré-escolar. Essas crianças foram submetidas ao teste Denver II, com um ano e novamente na idade préescolar quando foi aplicada a Escala de Maturidade Mental Colúmbia. METODOLOGIA ESTATÍSTICA: As variáveis contínuas serão descritas através de suas médias e desvios-padrão. Aquelas com comportamento não paramétrico, serão descritas através da mediana e do intervalo inter-quartil. As variáveis categóricas serão descritas através de suas proporções e intervalos de confiança de 95%. Para descartar a hipótese de nulidade será utilizado o nível de corte de 5%. RESULTADOS: Na amostra houve predominância do sexo feminino de 65%...

Age-age correlation for early selection of rubber tree genotypes in São Paulo State, Brazil

de Souza Gonçalves, Paulo; Bortoletto, Nelson; Cardinal, Átila Bento Beleti; Gouvêa, Lígia Regina Lima; da Costa, Reginaldo Brito; de Moraes, Mário Luiz Teixeira
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Artigo de Revista Científica Formato: 758-764
ENG
Relevância na Pesquisa
36.08%
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); In a field trial involving 68 rubber tree (Hevea spp.) clones calculation of genotypic correlation coefficients revealed significant age-age correlation from age 1 to 6 (immature period) for girth A and for age 7 to 12 (mature period) for girth B and for age 7 to 12 (production of latex) for yield. Rank correlation coefficients between all immature ages of girth (girth A), all ages of mature girth (girth B) and all annual rubber production (yield) were significant for the three traits, with the coefficients decreasing with increasing age. Selection of the sets of best 30, 15, 10 and 5 clones from the available 68 clones at a given age was generally accompanied by a descending order of percentage success. It was suggested: (a) to have the best 30 clones of age 6, select the set of best 36 clones at age 2, (b) to have the best 15 clones of age 6, select the set of best 20 clones at age 3, (c) to have the best 5 clones of age 6, select the set of best 8 clones at age 4, and (d) to have the best 3 clones of age 6, select the set of best 3 clones at age 5. More than 80% of the targeted clones on girth A or girth B basis and more than 76.7% clones on yield basis were found to get selected at steps (a) through (d). For achieving early multiplication of the most productive clone for deployment...

Obsessive-compulsive disorder: Influence of age at onset on comorbidity patterns

de Mathis, Maria Alice; do Rosario, Maria Conceição; Diniz, Juliana Belo; Torres, Albina Rodrigues; Shavitt, Roseli Gedanki; Ferrão, Ygor Arzeno; Fossaluza, Victor; de Bragança Pereira, Carlos Alberto; Miguel, Eurípedes Constantino
Fonte: Universidade Estadual Paulista Publicador: Universidade Estadual Paulista
Tipo: Artigo de Revista Científica Formato: 187-194
ENG
Relevância na Pesquisa
36.05%
Purpose: This study investigates the influence of age at onset of OCS on psychiatric comorbidities, and tries to establish a cut-off point for age at onset. Methods: Three hundred and thirty OCD patients were consecutively recruited and interviewed using the following structured interviews: Yale-Brown Obsessive Compulsive Scale; Yale Global Tic Severity Scale and the Structured Clinical Interview for DSM-IV. Data were analyzed with regression and cluster analysis. Results: Lower age at onset was associated with a higher probability of having comorbidity with tic, anxiety, somatoform, eating and impulse-control disorders. Longer illness duration was associated with lower chance of having tics. Female gender was associated with anxiety, eating and impulse-control disorders. Tic disorders were associated with anxiety disorders and attention-deficit/hyperactivity disorder. No cut-off age at onset was found to clearly divide the sample in homogeneous subgroups. However, cluster analyses revealed that differences started to emerge at the age of 10 and were more pronounced at the age of 17, suggesting that these were the best cut-off points on this sample. Conclusions: Age at onset is associated with specific comorbidity patterns in OCD patients. More prominent differences are obtained when analyzing age at onset as an absolute value. © 2008 Elsevier Masson SAS. All rights reserved.

Maternal morbidity and near miss associated with maternal age: the innovative approach of the 2006 Brazilian demographic health survey

Oliveira Jr,Fernando Cesar de; Costa,Maria Laura; Cecatti,Jose Guilherme; Silva,Joao Luiz Pinto e; Surita,Fernanda Garanhani
Fonte: Faculdade de Medicina / USP Publicador: Faculdade de Medicina / USP
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/07/2013 EN
Relevância na Pesquisa
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OBJECTIVE: To study the prevalence of potentially life-threatening maternal conditions and near miss in Brazil according to maternal age. METHODS: A secondary analysis of the 2006 Brazilian demographic health survey database using a validated questionnaire to evaluate maternal morbidity with a focus on age extremes. The study included 5,025 women with at least 1 live birth in the 5-year reference period preceding their interviews. Three age range periods were used: 15-19 years (younger age), 20-34 years (control), and 35-49 years (advanced maternal age). According to a pragmatic definition, any woman reporting eclampsia, hysterectomy, blood transfusion, or admission to the intensive care unit during her pregnancy/childbirth was considered a near-miss case. The associations between age and severe maternal morbidity were further assessed. RESULTS: For the 6,833 reported pregnancies, 73.7% of the women were 20-34 years old, 17.9% were of advanced maternal age, and only 8.4% were of younger age. More than 22% of the women had at least one of the complications appraised, and blood transfusion, which was more prevalent among the controls, was the only variable with a significant difference among the age groups. The overall rate of maternal near miss was 21.1 per 1000 live births. There was a trend of higher maternal near miss with increasing age. The only significant risk factor identified for maternal near miss was a lower literacy level among older women. CONCLUSIONS: There is a trend towards worse results with increasing age. The investigation of the determinants of maternal near miss at the community level using an innovative approach through a demographic health survey is an example suggested for under-resourced settings.

The relationship between age-stereotypes and health locus of control across adult age-groups

Sargent-Cox, Kerry; Anstey, Kaarin J
Fonte: Taylor & Francis Publicador: Taylor & Francis
Tipo: Artigo de Revista Científica Formato: 30 pages
Relevância na Pesquisa
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OBJECTIVE: This study integrates healthy ageing and health psychology theories to explore the mechanisms underlying the relationship between health control expectancies and age-attitudes on the process of ageing well. Specifically, the aim of this study is to investigate the relationship between age-stereotypes and health locus of control. DESIGN: A population-based survey of 739 adults aged 20 to 97 years (mean=57.3 years, SD=13.66; 42% female) explored attitudes towards ageing and health attitudes. A path-analytical approach was used to investigate moderating effects of age and gender. RESULTS: Higher age-stereotype endorsement was associated with higher chance (β=2.91, p<.001) and powerful other (β=1.07, p=.012) health expectancies, after controlling for age, gender, education and self-rated health. Significant age and gender interactions were found to influence the relationship between age-stereotypes and internal health locus of control. CONCLUSION: Our findings suggest that the relationship between age-stereotypes and health locus of control dimensions must be considered within the context of age and gender. The findings point to the importance of targeting health promotion and interventions through addressing negative age-attitudes.

Natural history and familial relationships of infant spilling to 9 years of age

Martin, A.; Pratt, N.; Kennedy, J.; Ryan, P.; Ruffin, R.; Miles, H.; Marley, J.
Fonte: Amer Acad Pediatrics Publicador: Amer Acad Pediatrics
Tipo: Artigo de Revista Científica
Publicado em //2002 EN
Relevância na Pesquisa
36.07%
Objectives. To determine the natural history of infant spilling (regurgitation/vomiting) during the first 2 years of life and to determine the relationship between infant spilling and gastroesophageal reflux (GER) symptoms at 9 years of age. Methods. A prospective birth cohort was followed with daily symptom diaries during the first 2 years of life and reviewed at 9 years of age (range: 8–11 years). The prevalence of infant spilling during the first 2 years of life, the prevalence of GER symptoms between 8 and 11 years of age (mean age: 9.7 years), relative risk of infant spilling predisposing to GER symptoms at 9 years of age, and prevalence of maternal GER symptoms and relationship with infant spilling and GER at 9 years of age were measured. Results. A total of 693 children who represented 83% of an original sample of 836 children and were followed for 2 years from birth with daily symptom diaries were contacted at 9 (8–11) years of age. Spilling of most feeds each day was common in infancy and reached a peak prevalence of 41% between 3 and 4 months of age and thereafter declined to < 5% between 13 and 14 months of age. Infants with spilling on 90 days or more during the first 2 years of life (classified as frequent spilling) were more likely to have GER symptoms at 9 years of age. Children with frequent infant spilling...

Increasing the age of gilts at first boar contact improves the timing and synchrony of the pubertal response but does not affect potential litter size

Van Wettere, W.; Revell, D.; Mitchell, M.; Hughes, P.
Fonte: Elsevier Science BV Publicador: Elsevier Science BV
Tipo: Artigo de Revista Científica
Publicado em //2006 EN
Relevância na Pesquisa
36.06%
One hundred and ninety-two Large White/Landrace crossbred gilts were used in this study. The study was conducted in two blocks, with 16 gilts allocated to each of six treatments in each block. The treatments compared the effects on puberty attainment of commencing boar exposure at 161, 182 or 203 days of age, and the effect of first mating gilts at either the pubertal or second oestrus on ovulation rate and early embryo survival. Boar contact took place in a detection-mating area (DMA), and consisted of 20 min/day of full contact with a vasectomized boar greater than ten months of age. Gilts were artificially inseminated at the allocated oestrus, with the reproductive tracts collected at 22.8 ± 0.4 days after first mating (mean ± S.E.M.), and the numbers of corpora lutea and viable embryos recorded. The age at which gilts attained puberty increased with the age at which boar exposure commenced. Mean gilt ages at puberty were 179.5 ± 1.6, 191.7 ± 1.2 and 210.3 ± 0.9 days, respectively, when boar contact commenced at 161, 182 and 203 days of age, P < 0.01. Mean days-to-puberty was significantly shorter when boar contact began at 182 and 203 days of age compared to 161 days of age (10.4 ± 1.2 and 8.3 ± 0.9 days versus 18.9 ± 1.5 days...

Exploring the need to update lung age equations

Newbury, W.; Newbury, J.; Briggs, N.; Crockett, A.
Fonte: Strategic Medical Publishing Publicador: Strategic Medical Publishing
Tipo: Artigo de Revista Científica
Publicado em //2010 EN
Relevância na Pesquisa
36.06%
AIMS: A renewed interest in lung age is evidenced by recent smoking cessation publications. This research compares the original Morris lung age equations (1985) with contemporary Australian lung age equations. METHODS: Both lung age equations were applied to the spirometry results of two sub-groups (never-smokers n=340, and current smokers n=50) from an independent dataset. Means of both lung age estimates were compared to the mean of the chronological age of each group by paired Student’s t-test. RESULTS: The Morris lung age estimates were paradoxically lower (younger) than chronological age in both groups. The new Australian equation produced lung age estimates that were equivalent to chronological age in the never-smoker group and significantly higher (older) than chronological age in the current smoker group. CONCLUSIONS: These results strongly suggest that the Morris lung age equations are in need of review. The use of contemporary lung age equations may translate into greater success for smoking cessation programs. The new Australian equations seem to possess internal validity.; Wendy Newbury, Jonathan Newbury, Nancy Briggs and Alan Crockett

Patterns of telomere length change with age in aquatic vertebrates and the phylogenetic distribution of the pattern among jawed vertebrates.

Izzo, Christopher
Fonte: Universidade de Adelaide Publicador: Universidade de Adelaide
Tipo: Tese de Doutorado
Publicado em //2010
Relevância na Pesquisa
36.09%
Telomeres, the protective caps at the ends of all vertebrate chromosomes, naturally undergo changes in length. These changes in telomere lengths may be a “molecular clock” by providing a counting mechanism of DNA replication events. In populations of jawed vertebrates (gnathostomes), telomere length has been shown to change with age; and thus measurements of telomere lengths may provide a novel means of determining the ages of free-living animals. Determinations of the age structure of populations of aquatic vertebrates (teleosts, chondrichthyans and marine mammals) are vital for sustainable management and conservation efforts. Yet, the commonly applied increment based ageing techniques are limited by the subjectivity of increment patterning and destructive sampling. I aimed to assess the application of telomere length as an age determinate for populations of aquatic vertebrates and to evaluate the biological implications and evolutionary origins of this trait amongst the gnathostomes. Telomere length change with age was investigated in an exemplar chondrichthyan, teleost and marine mammal species, to determine whether aquatic gnathostomes share the general pattern of declining telomeres with age, as found in terrestrial mammals. Chapter Two provides the first assessment of telomere length change with age in a chondrichthyan species...

Mitochondrial SIRT3 and its target glutamate dehydrogenase are altered in follicular cells of women with reduced ovarian reserve or advanced maternal age.

Pacella-Ince, Leanne; Zander-Fox, Deirdre Linda; Lane, Michelle
Fonte: Oxford University Press Publicador: Oxford University Press
Tipo: Artigo de Revista Científica
Publicado em //2014
Relevância na Pesquisa
36.06%
STUDY QUESTION Is the activity of sirtuin 3 (SIRT3) altered in granulosa and cumulus cells from young women with reduced ovarian reserve or women of advanced maternal age? SUMMARY ANSWER SIRT3 mRNA and active protein in granulosa and cumulus cells were decreased in women with reduced ovarian reserve and advanced maternal age. WHAT IS KNOWN ALREADY Young women with reduced ovarian reserve or women of advanced maternal age have reduced oocyte viability, possibly due to altered granulosa and cumulus cell metabolism. The mitochondrial SIRT3 protein may be implicated in these processes as it is able to sense the metabolic state of the cell and alter mitochondrial protein function post-translationally. STUDY DESIGN, SIZE, DURATION This is a prospective cohort study, in which women (n = 72) undergoing routine IVF/ICSI were recruited and allocated to one of three cohorts based on age and ovarian reserve (as assessed by serum anti-Mullerian hormone level). Women were classified as young (≤35 years) or of advanced maternal age (≥40 years). PARTICIPANTS/MATERIALS, SETTING, METHODS Granulosa and cumulus cells were collected. SIRT3 mRNA and protein levels and protein activity was analysed in granulosa and cumulus cells via quantitative PCR...

Quantitative analyses of long-run human capital development: age heaping as an indicator for numeracy; Quantitative Analyse langfristiger Humankapitalentwicklung: Age Heaping als Indikator für numerische Fähigkeiten

Crayen, Dorothee
Fonte: Universidade de Tubinga Publicador: Universidade de Tubinga
Tipo: Dissertação
EN
Relevância na Pesquisa
36.11%
For researchers studying the economic development of nations, the availability of human capital data is crucial. Economists making efforts to examine the impact of human resources on economic development before the end of World War II often face massive problems. Methods of collecting data, i.e., registration systems, population censuses or surveys did neither acquire sufficiently detailed data nor was the recorded data standardized in any consistent form and little attention was paid to direct information about a population’s level of education. For early time spans, more than any other data, demographic records are available. This thesis proposes to use irregularities in the reporting of age to estimate the people’s level of education. Single year age data, which enables researchers to depict a population’s detailed age structure, almost always exhibits irregularities in the form of heaped data, i.e., the age distribution does not run smoothly but exhibits sharp jumps and clustering at certain ages. This phenomenon is attributed to age heaping, a term which describes people’s ignorance to their age or people’s tendency to round their ages off. To a varying degree, age heaping exists in nearly all historical age statistics when people were asked for their age (as opposed to age records that were calculated from birth certificates or alike). By measuring the degree of age heaping one is able to derive a simple proxy for human capital covering a greater number of countries and regions as well as earlier periods than for instance signature ability rates. Being a proxy of numerical comprehension and diligence when responding to age questions...

A Idade do Bronze na bacia do Rio Ave (Noroeste de Portugal); The Bronze Age in the River Ave’s basin (Northwest of Portugal)

Sampaio, Hugo Aluai
Fonte: Universidade do Minho Publicador: Universidade do Minho
Tipo: Tese de Doutorado
Publicado em 19/09/2014 POR
Relevância na Pesquisa
36.07%
Tese de doutoramento em Arqueologia (área de especialização em Arqueologia da Paisagem e do Povoamento); Esta tese tem como principal objetivo aumentar o conhecimento sobre a Idade do Bronze da bacia do rio Ave, no Noroeste de Portugal. Através da articulação sincrónica e diacrónica dos dados nos seus contextos físico e cultural e à luz de novas premissas teóricas estudou-se este período de uma forma holística. Tal visa interpretar o modo como as comunidades se estruturaram no meio onde estavam imersas ou incorporadas e como interagiram com ele. Privilegiando a contextualização dos dados, nomeadamente os diferentes lugares construídos e frequentados pelas populações da Idade do Bronze, o estudo foi direcionado segundo três eixos temáticas, a saber: o povoamento, os contextos e as práticas funerárias e a metalurgia e as deposições metálicas. Foram, também, interpretados certos lugares “naturais”, cujas materialidades arqueológicas denunciavam ampla diacronia de frequência, traduzindo a sua importância na estruturação e na perceção do espaço por parte das populações da Idade do Bronze. No que respeita ao povoamento, apesar da ausência de dados para o Bronze Inicial, o Bronze Médio pauta-se pela ocupação multivariada do espaço. Prevalecem os sítios abrigados...

How Age-Friendly Are Kingston's Suburban Streets? A Comparative Case Study Analysis of Kingston, Ontario

Thibault, Jenna
Fonte: Quens University Publicador: Quens University
Tipo: Outros
EN
Relevância na Pesquisa
36.07%
Overview: There is a growing need to develop age-friendly communities to meet the challenges seniors face as they age (Cerda and Bernier, 2013). By the year 2050, the population will be comprised of a greater proportion of older people (aged 60 and over) than children (aged 0 to 14) for the first time in human history (Plouffe and Kalache, 2010). The World Health Organization (WHO) is trying to encourage cities to become more age-friendly and has identified eight key themes, relating to a city’s structures, environment, services and policies, which are conducive to a community that promotes active aging (WHO, 2007a). Although active aging is a complex concept and extends beyond solely ensuring that seniors remain physically active, designing neighbourhoods that promote mobility is critical since many seniors want to “age in place” (Smith, 2009). Seniors that experience fewer limitations on their mobility maintain a stronger sense of independence and control over their lives (Hodge, 2008). Since 2012, the City of Kingston has been engaged in the process of becoming classified as an age-friendly city (City of Kingston, 2012). The City’s commitment to this initiative provided the rationale for conducting age-friendly research in Kingston. Specifically...

Growth patterns in early childhood and the onset of menarche before age twelve

Martínez,Jeovany; Araújo,Cora; Horta,Bernardo Lessa; Gigante,Denise Petrucci
Fonte: Faculdade de Saúde Pública da Universidade de São Paulo Publicador: Faculdade de Saúde Pública da Universidade de São Paulo
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/04/2010 EN
Relevância na Pesquisa
36.08%
OBJECTIVE: To examine the relationship between growth patterns in early childhood and the onset of menarche before age 12. METHODS: The study included 2,083 women from a birth cohort study conducted in the city of Pelotas, Southern Brazil, starting in 1982. Anthropometric, behavioral, and pregnancy-related variables were collected through home interviews. Statistical analyses were performed using Pearson's chi-square and chi-square test for linear trends. A multivariable analysis was carried out using Poisson regression based on a hierarchical model. RESULTS: Mean age of menarche was 12.4 years old and the prevalence of menarche before age 12 was 24.3%. Higher weight-for-age, height-for-age, and weight-for-height z-scores at 19.4 and 43.1 months of age were associated with linear tendencies of increased prevalence and relative risks of the onset of menarche before age 12. Girls who experienced rapid growth in weight-for-age z-score from birth to 19.4 months of age and in weight-for-age or height-for-age z-scores from 19.4 to 43.1 months of age also showed higher risk of menarche before age 12. Higher risk was seen when rapid growth in weight-for-age z-score was seen during these age intervals and the highest risk was found among those in the first tertile of Williams' curve at birth. Rapid growth in weight-for-height z-score was not associated with menarche before age 12. CONCLUSIONS: Menarche is affected by nutritional status and growth patterns during early childhood. Preventing overweight and obesity during early childhood and keeping a "normal" growth pattern seem crucial for the prevention of health conditions during adulthood.

Risk factors of age-related macular degeneration in Argentina

Nano,María Eugenia; Lansingh,Van Charles; Pighin,María Soledad; Zarate,Natalia; Nano,Hugo; Carter,Marissa Janine; Furtado,João Marcello; Nano,Clelia Crespo; Vernengo,Luciana Fiocca; Luna,José Domingo; Eckert,Kristen Allison
Fonte: Conselho Brasileiro de Oftalmologia Publicador: Conselho Brasileiro de Oftalmologia
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/04/2013 EN
Relevância na Pesquisa
36.06%
PURPOSES: To assess the risk factors of age-related macular degeneration in Argentina using a case-control study. METHODS: Surveys were used for subjects' antioxidant intake, age/gender, race, body mass index, hypertension, diabetes (and type of treatment), smoking, sunlight exposure, red meat consumption, fish consumption, presence of age-related macular degeneration and family history of age-related macular degeneration. Main effects models for logistic regression and ordinal logistic regression were used to analyze the results. RESULTS: There were 175 cases and 175 controls with a mean age of 75.4 years and 75.5 years, respectively, of whom 236 (67.4%) were female. Of the cases with age-related macular degeneration, 159 (45.4%) had age-related macular degeneration in their left eyes, 154 (44.0%) in their right eyes, and 138 (39.4%) in both eyes. Of the cases with age-related macular degeneration in their left eyes, 47.8% had the dry type, 40.3% had the wet type, and the type was unknown for 11.9%. The comparable figures for right eyes were: 51.9%, 34.4%, and 13.7%, respectively. The main effects model was dominated by higher sunlight exposure (OR [odds ratio]: 3.3) and a family history of age-related macular degeneration (OR: 4.3). Other factors included hypertension (OR: 2.1)...

Confronting the Status Quo: Raising the Age of Juvenile Jurisdiction in North Carolina

Kaplan, David
Fonte: Universidade Duke Publicador: Universidade Duke
Tipo: Masters' project
Publicado em 03/05/2012 EN_US
Relevância na Pesquisa
36.1%
POLICY QUESTION (p.1) How can the case for increasing juvenile-status age in North Carolina be presented most effectively in the political arena? I. INTRODUCTION (p.1) North Carolina is one of two states (the other being New York) that end juvenile jurisdiction at age sixteen. This means that all sixteen and seventeen-year olds are processed as adults in the criminal justice system. Trying and sentencing youth as adults in the criminal system has serious and broad consequences for the offenders, their families, the criminal justice systems, and society at large. Youth in adult facilities are more prone to abuse; are less likely to receive health treatment and educational services; are more likely to join gangs and engage in violent behavior, and are more likely to recidivate. Further, adult convictions hinder access to employment and educational opportunities—two key sources that reduce the tendency to engage in criminal behavior. II. HISTORICAL DEVELOPMENT (p.4) The age of juvenile court jurisdiction in North Carolina is an old and contentious issue with much at stake. North Carolina set the maximum age of juvenile jurisdiction at age sixteen in 1919, over 90 years ago. The juvenile-status age has been looked at a number of times; however...

Padrões de crescimento na infância precoce e ocorrência de menarca antes de doze anos de idade; Patrones de crecimiento en la infancia precoz y ocurrencia de menarca antes de doce años de edad; Growth patterns in early childhood and the onset of menarche before age twelve

Martínez, Jeovany; Araújo, Cora; Horta, Bernardo Lessa; Gigante, Denise Petrucci
Fonte: Universidade de São Paulo. Faculdade de Saúde Pública Publicador: Universidade de São Paulo. Faculdade de Saúde Pública
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; ; Formato: application/pdf
Publicado em 01/04/2010 ENG
Relevância na Pesquisa
36.08%
OBJETIVO: Avaliar a relação entre padrões de crescimento na infância precoce e ocorrência de menarca antes de 12 anos de idade. MÉTODOS: O estudo incluiu 2.083 mulheres do estudo de coorte de nascidos em Pelotas, RS, de 1982. Variáveis antropométricas, comportamentais e relacionadas à gestação foram coletadas por meio de entrevistas domiciliares. As análises estatísticas empregadas foram o qui-quadrado de Pearson e qui-quadrado para tendência linear. Além disso, análise multivariável foi realizada usando a regressão de Poisson, seguindo um modelo hierárquico. RESULTADOS: A média de idade da menarca foi de 12,4 anos e a prevalência de menarca antes dos 12 anos foi de 24,3%. Maiores valores de escores Z nos índices peso/idade, altura/idade e peso/altura aos 19,4 e 43,1 meses corresponderam a maiores riscos de apresentar menarca antes dos 12 anos. Esse risco foi sistematicamente maior na idade de 43,1 meses. Meninas que experimentaram rápido crescimento em escore Z de peso/idade entre o nascimento e 19,4 meses ou em escore Z de peso/idade ou altura/idade entre 19,4 e 43,1 meses, mostraram os maiores riscos. O risco de menarca antes dos 12 anos foi mais elevado quando o crescimento rápido em escore Z de peso/idade ocorreu em ambos os períodos; e ainda maior entre as meninas do primeiro tercil da curva de Williams. Crescimento rápido em escore Z de peso/altura não esteve associado com menarca antes dos 12 anos. CONCLUSÕES: A idade da menarca mostrou-se influenciada pelo estado nutricional e padrões de crescimento durante a infância precoce. Assim...

Growth patterns in early childhood and the onset of menarche before age twelve

Martínez,Jeovany; Araújo,Cora; Horta,Bernardo Lessa; Gigante,Denise Petrucci
Fonte: Faculdade de Saúde Pública da Universidade de São Paulo Publicador: Faculdade de Saúde Pública da Universidade de São Paulo
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/04/2010 EN
Relevância na Pesquisa
36.08%
OBJECTIVE: To examine the relationship between growth patterns in early childhood and the onset of menarche before age 12. METHODS: The study included 2,083 women from a birth cohort study conducted in the city of Pelotas, Southern Brazil, starting in 1982. Anthropometric, behavioral, and pregnancy-related variables were collected through home interviews. Statistical analyses were performed using Pearson's chi-square and chi-square test for linear trends. A multivariable analysis was carried out using Poisson regression based on a hierarchical model. RESULTS: Mean age of menarche was 12.4 years old and the prevalence of menarche before age 12 was 24.3%. Higher weight-for-age, height-for-age, and weight-for-height z-scores at 19.4 and 43.1 months of age were associated with linear tendencies of increased prevalence and relative risks of the onset of menarche before age 12. Girls who experienced rapid growth in weight-for-age z-score from birth to 19.4 months of age and in weight-for-age or height-for-age z-scores from 19.4 to 43.1 months of age also showed higher risk of menarche before age 12. Higher risk was seen when rapid growth in weight-for-age z-score was seen during these age intervals and the highest risk was found among those in the first tertile of Williams' curve at birth. Rapid growth in weight-for-height z-score was not associated with menarche before age 12. CONCLUSIONS: Menarche is affected by nutritional status and growth patterns during early childhood. Preventing overweight and obesity during early childhood and keeping a "normal" growth pattern seem crucial for the prevention of health conditions during adulthood.