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Head-Centered Orientation Strategies in Animate Vision

Ballard, Dana Harry ; Grosso, Enrico
Fonte: University of Rochester. Computer Science Department. Publicador: University of Rochester. Computer Science Department.
Tipo: Relatório
ENG
Relevância na Pesquisa
36.35%
This paper is about orienting, that is, establishing and maintaining a spatial relation between a motorized pair of cameras (the eye-head system) and a static or a moving object tracked over time. Motivated by physiological evidence, the paper proposes a simple set of vision-based strategies aimed to perform head, eyes and body movements in a complex environment. Fixation is shown to be an essential feature in visual servoing, and it is used to decouple control on head rotational degrees of freedom, making possible a metric-less approach to the orientation problem. A running implementation of these strategies, using a binocular camera system mounted on a PUMA 700, demonstrates the effectiveness of the approach.

Investigating the effects of arousal state on cognitive performance in individuals with and without mild head injury

St. Cyr-Baker, Julie.
Fonte: Brock University Publicador: Brock University
Tipo: Electronic Thesis or Dissertation
ENG
Relevância na Pesquisa
36.35%
We examined the cognitive and emotional sequelae following mild head injury (MHI; e.g., concussion) in high-functioning individuals and whether persons with MHI pre~ent, both physiologically and via self-report, in a manner different from (i.e., underaroused) that of persons who have no history of head injury. We also investigated the effect arousal state ~as on the cognitive performance of this population. Using a quasiexperimental research design (N = 91), we examined changes in attention, working memory, and cognitive flexibility (subtests ofthe WAIS-III, 1997,WMS-III, 1997, & DKEFS, 2002) as a function of manipulated arousal (i.e., induced psychosocial stress/activation; reduced activation/relaxation). In addition to self-reported arousal and state anxiety (State-Trait Anxiety Inventory; Speilberger, 1983a) measures, physiological indices of arousal state (i.e., electrodermal responsivity, heart rate, and respiration activity) were recorded (via Polygraph Professional Suite, 2008) across a 2.5 hour interval while completing various cognitive tasks. Students also completed the Post-concussive Symptom Checklist (Gouvier et aI., 1992). The results demonstrate that university students who report a history ofMHI (i.e....

Diffuse neuronal perikaryon amyloid precursor protein immunoreactivity in a focal head impact model

Van Den Heuvel, C.; Lewis, S.; Wong, M.; Manavis, J.; Finnie, J.; Blumbergs, P.; Jones, N.; Reilly, P.
Fonte: SPRINGER-VERLAG WIEN Publicador: SPRINGER-VERLAG WIEN
Tipo: Artigo de Revista Científica
Publicado em //1998 EN
Relevância na Pesquisa
36.35%
Amyloid precursor protein (APP) has been shown to accumulate in traumatically injured axons as early as 1 hour after injury. This accumulation may be due to interruption of fast axoplasmic transport and/or upregulation of APP synthesis. The aim of this study was to examine the neuronal cell body response to head impact using APP immunostaining in a focal non-missile head impact model. Ten anaesthetised and ventilated 2 year old Merino ewes were subjected to graded impact in the left temporal region by captive bolt. 2 hours after impact the brain was perfused fixed with formaldehyde. The tissue was mounted in paraffin, sectioned and stained with a monoclonal antibody to APP and standard H&E stain. APP positivity was semi-quantitated using a modification of our previously described sector scoring system [1]. Widespread neuronal APP positivity was found in the cerebral hemispheres and brain stem distant from the site of focal injury in all 10 animals. The most prominent APP positivity was found in the nerve cell bodies of the impacted left cerebral hemisphere. APP positive neurons were also found within regions which were structurally normal when stained with H&E. These results demonstrate diffuse neuronal perikaryon APP immunoreactivity following a focal head impact injury. The expression of APP within the neuronal cell body may be due to upregulation of APP synthesis or alterations in the availability of epitopes of APP. Further studies are in progress to address these hypotheses.

Cerebral oxygenation monitoring by near-infrared spectroscopy is not clinically useful in patients with severe closed-head injury: a comparison with jugular venous bulb oximetry

Lewis, S.; Myburgh, J.; Thornton, E.; Reilly, P.
Fonte: Williams & Wilkins Publicador: Williams & Wilkins
Tipo: Artigo de Revista Científica
Publicado em //1996 EN
Relevância na Pesquisa
36.35%
OBJECTIVE: To compare continuous jugular venous bulb oximetry and cerebral near-infrared spectroscopy in patients with severe closed head injury. DESIGN: A prospective observational study. SETTING: Intensive care unit of a major teaching hospital. PATIENTS: Adults (n = 10) with severe closed-head injury (Glasgow Coma Scale score of < or = 8). INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Jugular venous bulb oximetry, cerebral near-infrared spectroscopy, and cerebral perfusion pressure were measured continuously. A total of 3,691 paired measurements of near-infrared spectroscopy and jugular venous bulb oximetry were analyzed. Poor correlation (r2 = .04) between paired measurements and wide limits of agreement (-13% to +21%) were demonstrated. The mean difference between measurements was +/- 4% and the standard deviation of the mean difference was +/- 8.69%. The data were subsequently grouped according to three clinically significant subgroups of jugular venous bulb oxygen saturation reflecting low ( < 55%), normal (55% to 75%) and high ( > 75%) saturation values. Poor correlation and wide limits of agreement between the two methods of measurement were observed in all groups. Values recorded by near-infrared spectroscopy did not significantly change between the groups...

An evaluation of head position and craniofacial reference line variation

Barbera, A.; Sampson, W.; Townsend, G.
Fonte: Urban & Fischer Verlag Publicador: Urban & Fischer Verlag
Tipo: Artigo de Revista Científica
Publicado em //2009 EN
Relevância na Pesquisa
36.35%
Natural head position (NHP) is the usual, balanced position of the head which is adopted for viewing the horizon or an object at eye level. Determination of NHP is useful when reconstructing facial form in art, forensics, orthodontic diagnosis and treatment planning for surgical management of craniofacial dysmorphic conditions. When NHP is uncertain, correction such as orientation to Frankfurt horizontal (FH) has been advocated. However, FH angulation varies between individuals and is subject to landmark identification error. Previous studies have measured FH and other craniofacial planes in relation to the true horizontal (HOR) with subjects in NHP and have found similar variation to that found with FH. This study measured craniofacial planes in 40 Aboriginal Australians (20 male, 20 female, aged 17 years or greater) from lateral cephalographs and compared its results with classical previous studies. Four planes, the neutral horizontal axis (NHA), FH, Krogman-Walker line (KW line), and palatal plane (P plane) demonstrated near parallelism and averaged between -1 degrees and -2 degrees from HOR. The combined use of NHA, FH, KW line, and P plane enables more effective corrected head position (CHP).; Andrew L. Barbera, Wayne J. Sampson...

Patient-reported measurements of oral mucositis in head and neck cancer patients treated with radiotherapy with or without chemotherapy: Demonstration of increased frequency, severity, resistance to palliation, and impact on quality of life

Elting, L.; Keefe, D.; Sonis, S.; Garden, A.; Spijkervet, F.; Barasch, A.; Tishler, R.; Canty, T.; Kudrimoti, M.; Vera-Llonch, M.
Fonte: John Wiley & Sons Inc Publicador: John Wiley & Sons Inc
Tipo: Artigo de Revista Científica
Publicado em //2008 EN
Relevância na Pesquisa
36.35%
BACKGROUND: The risk, severity, and patient-reported outcomes of radiation-induced mucositis among head and neck cancer patients were prospectively estimated. METHODS: A validated, patient-reported questionnaire (OMDQ), the FACT quality of life (QOL), and the Functional Assessment of Chronic Illness Therapy (FACIT) fatigue scales were used to measure mucositis (reported as mouth and throat soreness), daily functioning, and use of analgesics. Patients were studied before radiotherapy (RT), daily during RT, and for 4 weeks after RT. RESULTS: Contrary to previous reports, the risk of mucositis was virtually identical in the 126 patients with oral cavity or oropharynx tumors (99% overall; 85% grade 3-4) compared with 65 patients with tumors of the larynx or hypopharynx (98% overall; 77% grade 3-4). The mean QOL score decreased significantly during RT, from 85.1 at baseline to 69.0 at Week 6, corresponding with the peak of mucositis severity. The mean functional status score decreased by 33% from 18.3 at baseline to 12.3 at Week 6. The impact of mucositis on QOL was proportional to its severity, although even a score of 1 or 2 (mild or moderate) was associated with a significant reduction in QOL (from 93.6 at baseline to 74.7 at Week 6). Despite increases in analgesic use from 34% at baseline to 80% at Week 6...

Long term survival following the detection of circulating tumour cells in head and neck squamous cell carcinoma

Winter, S.; Stephenson, S.; Subramaniam, S.; Paleri, V.; Ha, K.; Marnane, C.; Krishnan, S.; Rees, G.
Fonte: BioMed Central Ltd. Publicador: BioMed Central Ltd.
Tipo: Artigo de Revista Científica
Publicado em //2009 EN
Relevância na Pesquisa
36.35%
Background: Techniques for detecting circulating tumor cells in the peripheral blood of patients with head and neck cancers may identify individuals likely to benefit from early systemic treatment. Methods: Reconstruction experiments were used to optimise immunomagnetic enrichment and RT-PCR detection of circulating tumor cells using four markers (ELF3, CK19, EGFR and EphB4). This method was then tested in a pilot study using samples from 16 patients with advanced head and neck carcinomas. Results: Seven patients were positive for circulating tumour cells both prior to and after surgery, 4 patients were positive prior to but not after surgery, 3 patients were positive after but not prior to surgery and 2 patients were negative. Two patients tested positive for circulating cells but there was no other evidence of tumor spread. Given this patient cohort had mostly advanced disease, as expected the detection of circulating tumour cells was not associated with significant differences in overall or disease free survival. Conclusion: For the first time, we show that almost all patients with advanced head and neck cancers have circulating cells at the time of surgery. The clinical application of techniques for detection of spreading disease...

Neuropathological changes in a lamb model of non-accidental head injury (the shaken baby syndrome)

Finnie, J.; Blumbergs, P.; Manavis, J.; Turner, R.; Helps, S.; Vink, R.; Byard, R.; Chidlow, G.; Sandoz, B.; Dutschke, J.; Anderson, R.
Fonte: Churchill Livingstone Publicador: Churchill Livingstone
Tipo: Artigo de Revista Científica
Publicado em //2012 EN
Relevância na Pesquisa
36.35%
Non-accidental head injury (NAHI), also termed the "shaken baby syndrome", is a major cause of death and severe neurological dysfunction in children under three years of age, but it is debated whether shaking alone is sufficient to produce brain injury and mortality or whether an additional head impact is required. In an attempt to resolve this question, we used a lamb model of NAHI since these animals have a relatively large gyrencephalic brain and weak neck muscles resembling those of a human infant. Three anaesthetised lambs of lower body weight than others in the experimental group died unexpectedly after being shaken, proving that shaking alone can be lethal. In these lambs, axonal injury, neuronal reaction and albumin extravasation were widely distributed in the hemispheric white matter, brainstem and at the craniocervical junction, and of much greater magnitude than in higher body weight lambs which did not die. Moreover, in the eyes of these shaken lambs, there was damage to retinal inner nuclear layer neurons, mild, patchy ganglion cell axonal injury, widespread Muller glial reaction, and uveal albumin extravasation. This study proved that shaking of a subset of lambs can result in death, without an additional head impact being required.; J.W. Finnie...

Prevention of oral mucositis in head and neck cancer patients : a systematic review.

Bowen, Joanne
Fonte: Universidade de Adelaide Publicador: Universidade de Adelaide
Tipo: Tese de Doutorado
Publicado em //2012
Relevância na Pesquisa
36.35%
Oral mucositis is a common and costly consequence of cancer treatment that currently lacks adequate intervention options. Patients treated for head and neck malignancies are at particularly high risk of severe mucositis, which significantly impedes delivery of therapy and consequently results in poorer outcomes in this population. As such, the quantitative objective of this review was to identify the effectiveness of agents and devices for oral mucositis prevention in newly diagnosed adult head & neck cancer patients being treated with radiotherapy with or without chemotherapy. The methodological framework developed by the Joanna Briggs Institute was followed to conduct the review. The quantitative component of the review considered any randomised controlled trials. In the absence of RCTs other research designs, such as non-randomised controlled trials and before and after studies, were considered for inclusion in a narrative summary to enable the identification of current best evidence. Databases were searched for published and non-published studies. A total of 202 studies were retrieved for review, with 81 studies excluded after reading the full article for clearly not meeting the inclusion criteria of the review. Two reviewers independently assessed 123 studies for methodological quality...

Improving therapeutic ratio In head and neck cancer with adjuvant and cisplatin-based treatments

Marcu, L.
Fonte: Hindawi Publishing Corporation Publicador: Hindawi Publishing Corporation
Tipo: Artigo de Revista Científica
Publicado em //2013 EN
Relevância na Pesquisa
36.35%
Advanced head and neck cancers are difficult to manage despite the large treatment arsenal currently available. The multidisciplinary effort to increase disease-free survival and diminish normal tissue toxicity was rewarded with better locoregional control and sometimes fewer side effects. Nevertheless, locoregional recurrence is still one of the main reasons for treatment failure. Today, the standard of care in head and neck cancer management is represented by altered fractionation radiotherapy combined with platinum-based chemotherapy. Targeted therapies as well as chronotherapy were trialled with more or less success. The aim of the current work is to review the available techniques, which could contribute towards a higher therapeutic ratio in the treatment of advanced head and neck cancer patients.; Loredana G. Marcu

Amifostin in subkutaner Anwendung bei Patienten mit Kopf-Hals-Tumoren; Subcutaneous application of amifostine on patients with head and neck cancer

Wilder, Daniel
Fonte: Universidade de Tubinga Publicador: Universidade de Tubinga
Tipo: Dissertação
DE_DE
Relevância na Pesquisa
36.35%
Hintergrund: Amifostin (Ethyol®), ein phosphorylierter Aminothioalkohol mit der chemischen Bezeichnung S-2[3-aminopropylamino]-ethyl-thiophosphorsäure, ist eine Substanz mit einem breiten zytoprotektiven Spektrum für die radio- und chemotherapeutisch induzierten Nebenwirkungen. Die Substanz fungiert dabei im Sinne einer Prodrug. Daraus wird, in Abhängigkeit von der alkalischen Phosphatase, der dephosphorylierte aktive Metaboliten WR-1065 gebildet. Dieser ist für die protektiven Wirkungen hauptsächlich verantwortlich. Weitere Oxidationen führen zu den entsprechenden symmetrischen (WR-33278) und gemischten Disulfiden. Die Zulassung der Substanz ist bisher lediglich auf eine intravenöse Applikation beschränkt. Hier zeigten sich bei radiotherapeutisch behandelten Patienten mit Kopf-Hals-Tumoren eine signifikante Reduktion einer Xerostomie und eine wesentlich höhere Lebensqualität der betroffenen Patienten. Präklinische Daten weisen auf eine signifikante Bioverfügbarkeit dieser Substanz auch bei einer subkutanen Applikation hin. In der vorliegenden Arbeit sollten erstmals umfangreiche Daten zur Pharmakokinetik von Amifostin und seiner Metaboliten, dem klinischem Outcome und Verträglichkeit für die subkutane Anwendung, im direkten Vergleich mit einer intravenösen Kontrollgruppe...

Monte-Carlo-Simulation des Strahlungstransports im Strahlerkopf eines Elektronenlinearbeschleunigers; The Monte Carlo Simulation of the radiation transport in the Radiation head of an electron linear accelerator

Haryanto, Freddy
Fonte: Universidade de Tubinga Publicador: Universidade de Tubinga
Tipo: Dissertação
DE_DE
Relevância na Pesquisa
36.35%
Dok. 1: Dissertation - Textteil Dok. 2 - 5: Anhänge ********************************* Diese Arbeit wurde verfasst, um einen Strahlerkopf für den Strahlungstransport von 6 MV und 15 MV Röntgenstrahlung anhand des Monte-Carlo-Verfahrens zu modellieren. Gestützt auf die Ergebnisse der Arbeit, kann die Dosisberechnung bei Bestrahlungstechniken, insbesondere bei solchen mit fluenzmodulierten Strahlenfeldern, mit der für die klinische Anwendung erforderlichen Genauigkeit durchgeführt werden. Darüber hinaus finden die mit diesen Modellen durchgeführten Simulationen Verwendung, um die entsprechenden Messungen zu verifizieren oder um die bei den Messungen gefundenen Phänomene zu erklären. Zu Beginn wurden sechs Modelle für jede Strahlungsqualität entworfen. Die Parameter der Elektronenquelle wurden für alle sechs Modelle variiert, um die Einflüsse der Parameter der Elektronenquelle auf die Strahlungsfeldgrößen für Röntgenstrahlung und auf die Dosisverteilung im Wasserphantom beobachten zu können. Dabei ergaben sich folgende Resultate : Die Energie der Elektronenquelle spielt eine wichtige Rolle sowohl für die Strahlungsfeldgrößen für Röntgenstrahlung als auch für die Dosisverteilung im Wasserphantom. Die Elektronenenergie beeinflusst nicht nur die Zahl der auf den Phasenraum treffenden Photonen...

Analysis of Pigeons' Head and Body Movements While Pecking

Reid, Thomas
Fonte: Quens University Publicador: Quens University
Tipo: Tese de Doutorado
EN; EN
Relevância na Pesquisa
36.35%
Pigeons have been shown to follow a specific sequence of behaviour while pecking. The pecking motion appears to be a single continuous movement, however video analysis examined at frame rates slower than real-time has shown that pigeons briefly stop the movement of their head twice during a single peck. After the second stop, they initiate a final ballistic movement which terminates when they make contact with a target (Goodale, 1983). It has been hypothesized that during the first stop (or fixation) phase pigeons are making the decision whether or not to peck the target. During the second stop phase pigeons are thought to calculate finer details of the target such as its specific size and depth as well as program the final motor movement needed to make an accurate peck. The current experiment was designed to analyze the function of the second stop phase by varying target size. Four pigeons were trained on a task involving pecking at five sizes of stimuli for a food reward, and the movements of their heads and bodies were recorded during pecking as well as walking towards the screen where the targets appeared. The main hypothesis, that the duration of the second stop phase would increase as stimulus size decreased, was tentatively supported; the data followed the hypothesized trend across all sizes of stimuli except the largest. Other interesting findings concerning head and body movement were also found...

Depression, fatigue, and health-related quality of life in head and neck cancer patients: a prospective pilot study

Sawada, Namie Okino; de Paula, Juliana Maria; Sonobe, Helena Megumi; Fontao Zago, Marcia Maria; Guerrero, Giselle Patricia; Nicolussi, Adriana Cristina
Fonte: SPRINGER; NEW YORK Publicador: SPRINGER; NEW YORK
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
36.35%
To assess the prevalence of depression and fatigue symptoms in head and neck cancer patients during radiotherapy treatment and relate them symptoms with these patients' quality of life. This is a prospective study. The Beck Depression Inventory (BDI), Piper Fatigue Scale-revised and Functional Assessment Cancer Therapy Head and Neck (FACT-H&N) were applied to 41 head and neck cancer patients at three times: at the start of treatment (T1), approximately 15 days after the start of treatment (T2) and at the end of treatment (T3), approximately 30 days after the start of the radiotherapy. The mean BDI and PIPER increased during the radiotherapy treatment. BDI scores did not demonstrate the presence of depression, although the number of symptoms increased, and the presence of fatigue rose as treatment advanced. The mean FACT H&N decreased in the middle and at the end of treatment, indicating worsening in these patients' Quality of Life. Depression and fatigue symptoms increased during radiotherapy treatment, while QoL levels decreased. This demonstrates that these symptoms are strongly correlated and that their presence negatively influenced QoL. At the start of treatment, nurses need to advise patients and plan care, offering interventions to decrease these symptoms and improve QoL.

Fatores preditivos do maior número de estádios na cirurgia micrográfica de Mohs para o tratamento do carcinoma espinocelular da cabeça; Predictors of higher number of stages in Mohs micrographic surgery for the treatment of squamous cell carcinoma of the head

TERZIAN, Luiz Roberto; FESTA NETO, Cyro; PIMENTEL, Eugênio Raul de Almeida
Fonte: Sociedade Brasileira de Dermatologia Publicador: Sociedade Brasileira de Dermatologia
Tipo: Artigo de Revista Científica
POR
Relevância na Pesquisa
36.35%
FUNDAMENTOS: Os carcinomas espinocelulares da pele da cabeça têm como opção terapêutica mais segura a cirurgia micrográfica de Mohs, que apresenta os menores índices de recidiva e a máxima preservação tecidual. Características dos carcinomas espinocelulares podem estar relacionadas a maior número de estádios cirúrgicos. OBJETIVO: Definir características dos carcinomas espinocelulares que sejam preditoras de maior número de estádios na cirurgia de Mohs. MÉTODOS: Análise retrospectiva de 51 carcinomas espinocelulares da cabeça tratados pela cirurgia de Mohs para determinar fatores de risco de maior número de estádios. Foram analisados limites clínicos, morfologia, recidiva, histologia e tamanho, relacionando-os ao número de estádios cirúrgicos. A análise estatística foi realizada pelo teste exato de Fisher e regressão logística multivariada. RESULTADOS: Os carcinomas recidivados tiveram tendência a maior número de estádios (p=0,081). Os tumores com limites imprecisos apresentaram três vezes mais possibilidades de maior número de fases na análise da razão de chances. Esse achado foi compatível com dados da literatura, apesar de não ter sido estatisticamente significante. CONCLUSÃO: Características pré-operatórias dos carcinomas espinocelulares...

Studies comparing surrogate measures for head posture in individuals with and without neck pain

Silva, A; Sharples, P; Johnson, M. I.
Fonte: Maney Publishing Publicador: Maney Publishing
Tipo: Artigo de Revista Científica
ENG
Relevância na Pesquisa
36.35%
Background: Head posture (HP) assessment of patients with neck pain (NP) is claimed to be useful in aiding diagnosis, determining treatment strategies and monitoring patient progress. It is assumed that patients with NP have poorer HP than asymptomatic individuals. Objectives: To determine whether there are differences in angles or linear distances between anatomical landmarks used as surrogates for HP between individuals with and without NP. Methods: Studies were sought from PubMed, CINAHL, Physiotherapy Evidence Database, Sports Discus, Web of Science, Academic Search Premier and The Cochrane Library. Two reviewers screened titles and abstracts, and assessed full reports for potentially eligible studies. Data extraction and synthesis: Two reviewers independently extracted information on participants' characteristics, study methods and study quality. Discrepancies were resolved using a third reviewer as arbiter. Study heterogeneity prevented meta-analysis so a tally of study outcome was performed. Results: Seven of 13 included studies found no statistically significant differences in measurements of components of HP between participants with NP and asymptomatic participants. When compared to asymptomatic individuals NP patients were found to have greater forward HP in 4 of 19 comparisons (11 studies)...

Schwannomas in the head and neck: retrospective analysis of 21 patients and review of the literature

Langner,Erwin; Del Negro,André; Akashi,Hugo Kenzo; Araújo,Priscila Pereira Costa; Tincani,Alfio José; Martins,Antonio Santos
Fonte: Associação Paulista de Medicina - APM Publicador: Associação Paulista de Medicina - APM
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/07/2007 EN
Relevância na Pesquisa
36.35%
CONTEXT AND OBJECTIVE: Schwannomas are benign neoplasms of the peripheral nerves originating in the Schwann cells. According to their cellularity, they can be subdivided into Antoni A or Antoni B types. They are rare and usually solitary, with clearly delimited capsules. They occur in the head and neck region in only 25% of the cases, and may be associated with Von Recklinghausen's disease. The present study retrospectively analyzed some data on this disease in the head and neck region and reviewed the literature on the subject. DESIGN AND SETTING: Retrospective study at Head and Neck Service, Universidade Estadual de Campinas. METHODS: Data on 21 patients between 1980 and 2003 were reviewed. The sites of cervical schwannomas and the intraoperative, histopathological and postoperative clinical status of these cases were studied. Diagnostic methods, type of surgery and association with neurofibromatosis were evaluated. RESULTS: The patients' ages ranged from 16 to 72 years. Four patients had a positive past history of type I neurofibromatosis or Von Recklinghausen's disease. The nerves affected included the brachial and cervical plexuses, vagus nerve, sympathetic chain and lingual or recurrent laryngeal nerve. The nerve of origin was not identified in six cases. Tumor enucleation was performed in 16 patients; the other five required more extensive surgery. CONCLUSION: Schwannomas and neurofibromas both derive from Schwann cells...

Undifferentiated head and neck tumors: the contribution of immunohistochemical technique to differential diagnosis

Bianchini,Walter Adriano; Altemani,Albina Maria; Paschoal,Jorge Rizzato
Fonte: Associação Paulista de Medicina - APM Publicador: Associação Paulista de Medicina - APM
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2003 EN
Relevância na Pesquisa
36.35%
CONTEXT: Undifferentiated head and neck and skull base tumors are not unusual. They can arise in mucosa as well as in salivary glands, soft tissues or lymph nodes. Suitable therapy and prognosis for each case depends upon precise histopathological diagnosis. OBJECTIVE: To evaluate the role of immunohistochemical techniques in determining the conclusive diagnosis. The occurrence of these tumors in our service and the way in which they were distributed according to cell pattern, patient's age and tumor location was also evaluated. TYPE OF STUDY: Cross-sectional study. SETTING: Hospital das Clínicas, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil. PARTICIPANTS: 43 biopsies performed between January 1990 and December 1997, diagnosed as undifferentiated head and neck tumors. PROCEDURES: We applied an immunohistochemical panel in accordance with the avidin-biotin-peroxidase complex method. The final diagnosis was achieved after new analysis in conjunction with biopsies stained using the hematoxylin-eosin technique. MAIN MEASUREMENTS: This study evaluated undifferentiated tumors in head and neck, and the way in which they were distributed, according to cell pattern, patient's age and tumor location. RESULTS: The most frequent locations for undifferentiated tumors were the lymph nodes...

Correlação entre postura da cabeça, intensidade da dor e índice de incapacidade cervical em mulheres com queixa de dor cervical; Correlation between head posture, pain and disability index neck in women with complaints of neck pain

Soares, Juliana Corrêa; Weber, Priscila; Trevisan, Maria Elaine; Trevisan, Claudia Morais; Rossi, Angela Garcia
Fonte: Universidade de São Paulo. Faculdade de Medicina Publicador: Universidade de São Paulo. Faculdade de Medicina
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; Formato: application/pdf
Publicado em 01/03/2012 POR
Relevância na Pesquisa
36.35%
Neck pain is the most common symptom of cervical dysfunctions often being related to the maintenance of postures. Postural changes of the head are often associated with the occurrence of neck pain with an anterior approach was the most frequent. The purpose was to investigate the correlation between head posture, pain intensity and neck disability index. The study group (SG) was composed of women, aged between 20 and 50 years who complained of neck pain for more than three months, and the control group (CG) for asymptomatic women. Pain intensity was assessed by visual analogue scale (VAS), disability by neck disability index (NDI) and the head posture by the craniovertebral angle (CV). Normality of the data was verified by the Lilliefors test and the comparison between groups by the Student's t-test for independent samples, and the association between variables by Spearman correlation test. Significance level was 5%. The SG had lower average CV for the angle (p=0.02). The CV angle was negatively correlated with the VAS (r=-0.48) and NDI (r=-0.15) suggesting that the smaller the angle, the greater the intensity of neck pain and disability. The NDI and VAS showed a positive correlation (r=0.59). The angle CV in subjects with neck pain was significantly lower than in healthy individuals association with the neck disability index and pain.; A dor cervical é o sintoma mais comum das disfunções cervicais...

The Need for Adaptive Intensity Modulated Radiotherapy Replanning in Head-and-Neck Patients with Anatomical Changes During Treatment

Rhee, Dong Joo
Fonte: Universidade Duke Publicador: Universidade Duke
Tipo: Tese de Doutorado
Publicado em //2013
Relevância na Pesquisa
36.35%

Abstract

Purpose: The aim of this study is to quantify the effectiveness of adaptive radiation therapy (ART) when anatomical changes to the tumor and/or the organs are observed for head and neck patients during the course of intensity modulated radiation therapy (IMRT).

Methods and Materials: In this study, ART was retrospectively studied in 10 head and neck cancer treated patients after examining the 2nd CT, obtained after the first several fractions of radiotherapy, to see if anatomical changes had taken place. The adaptive treatment plan (ATP) was generated on the 2nd CT to mimic the relative dose-volume histograms of the spinal cord, brainstem, parotid glands, larynx, and oral cavity from the original treatment plan. The total ATP was generated as the sum of the original treatment plan delivered to the initial CT for the first several fractions and the ATP delivered to the 2nd CT for the remaining fractions. The delivered treatment plan (DTP) was generated as the sum of the original treatment plan delivered to the initial CT for the first several fractions and the original treatment plan delivered to the 2nd CT for the remaining fractions. For quantification of the effectiveness of ART, planning target volume (PTV) coverage and homogeneity...