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Maternal Serum Heme-Oxygenase-1 (HO-1) Concentrations in Early Pregnancy and Subsequent Risk of Gestational Diabetes Mellitus

Qiu, Chunfang; Hevner, Karin; Enquobahrie, Daniel A.; Williams, Michelle A
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
EN_US
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Background: Heme oxygenase-1 (HO-1) concentrations have been recently reported to be elevated in impaired glucose tolerance and type 2 diabetes mellitus (T2DM). However, no study has examined the association between HO-1 concentrations and gestational diabetes mellitus (GDM). Methods: In a case-control study, nested within a prospective cohort of pregnant women (186 GDM cases and 191 women who remained eu-glycemic through pregnancy), we assessed the association of maternal serum HO-1 concentrations, measured in samples collected at 16 weeks gestation, on average, with subsequent risk of GDM. Maternal serum HO-1 concentrations were determined using ELISA. We fitted multivariate logistic regression models to derive estimates of odds ratios (ORs) and 95% confidence intervals (CIs). Results: Median serum HO-1 concentrations in early pregnancy were lower in women who subsequently developed GDM compared with those who did not (1.60 vs. 1.80 ng/mL, p-value = 0.002). After adjusting for maternal age, race, family history of T2DM and pre-pregnancy body mass index, women with HO-1≥3.05 ng/mL (highest decile) experienced a 74% reduction of GDM risk (95% CI; 0.09–0.77) compared with women whose concentrations were<1.23 ng/mL (lowest quartile). Conclusion: Serum HO-1 concentrations were inversely associated with subsequent GDM risk. These findings underscore the role of oxidative stress in the pathogenesis of GDM. Additional studies are warranted to confirm the clinical utility of serum HO-1 in diagnosis of GDM...

Preterm Birth and Antidepressant Medication Use during Pregnancy: A Systematic Review and Meta-Analysis

Huybrechts, Krista F.; Sanghani, Reesha Shah; Avorn, Jerry; Urato, Adam C.
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
EN_US
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Introduction: Preterm birth is a major contributor to neonatal morbidity and mortality and its rate has been increasing over the past two decades. Antidepressant medication use during pregnancy has also been rising, with rates up to 7.5% in the US. The objective was to systematically review the literature to determine the strength of the available evidence relating to a possible association between antidepressant use during pregnancy and preterm birth. Methods: We conducted a computerized search in PUBMED, MEDLINE and PsycINFO through September 2012, supplemented with a manual search of reference lists, to identify original published research on preterm birth rates in women taking antidepressants during pregnancy. Data were independently extracted by two reviewers, and absolute and relative risks abstracted or calculated. Our a priori design was to group studies by level of confounding adjustment and by timing of antidepressant use during pregnancy; we used random-effects models to calculate summary measures of effect. Results: Forty-one studies met inclusion criteria. Pooled adjusted odds ratios (95% CI) were 1.53 (1.40–1.66) for antidepressant use at any time and 1.96 (1.62–2.38) for 3rd trimester use. Controlling for a diagnosis of depression did not eliminate the effect. There was no increased risk [1.16 (0.92–1.45)] in studies that identified patients based on 1st trimester exposure. Sensitivity analyses demonstrated unmeasured confounding would have to be strong to account for the observed association. Discussion Published evidence is consistent with an increased risk of preterm birth in women taking antidepressants during the 2nd and 3rd trimesters...

Pregnancy diagnosis, fetal quantification and gender estimation by ultra-sonography in ewes

Dias,Lilian Mara Kirsch; Souza,José Camisão de; Assis,Roberta de Moura; Raymundo,Camila de Moraes
Fonte: Editora da Universidade Federal de Lavras Publicador: Editora da Universidade Federal de Lavras
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/06/2009 EN
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The objective of this experiment was to evaluate the accuracy of gestation, fetal sexing and quantification diagnoses in ewes. Pregnancy and fetal quantification were diagnosed in 105 ewes at 35 days of pregnancy. For the fetal gender diagnosis sexing diagnose 55 ewes between 49 and 59 days of pregnancy were used. All exams were recorded on DVD for posterior analysis. After birth, lamb sex was recorded to determine fetal sexing precision. Data were analyzed by chisquare (χ2) or Fisher's test, with a significance of 0.05. One hundred percent of pregnancy ultrasound diagnoses were correct. As for the fetal quantification diagnoses, there was an error of 12%. It was possible to diagnose the fetal sex in 87% of the 69 examined fetuses, and 90% of these were estimated correctly. The real-time ultrasound diagnoses were not different from the recorded DVD image diagnoses. Therefore, pregnancy diagnosis accuracy may reach 100%, differing from fetal gender estimation and quantification, which are dependent upon other variables such as fetal gender and examiner experience.

Gestação e a constituição da maternidade; Pregnancy and motherhood; Gestación y la constitución de la maternidad

Piccinini, Cesar Augusto; Lopes, Rita de Cassia Sobreira; Gomes, Aline Grill; De Nardi, Tatiana de C.
Fonte: Universidade Federal do Rio Grande do Sul Publicador: Universidade Federal do Rio Grande do Sul
Tipo: Artigo de Revista Científica Formato: application/pdf
POR
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Na gravidez ocorrem mudanças biológicas, somáticas, psicológicas e sociais que influenciam a dinâmica psíquica individual e as demais relações sociais da gestante, e maneira como ela vive estas mudanças repercute intensamente na constituição da maternidade e na relação mãe-bebê. Assim sendo, o objetivo deste estudo foi investigar os sentimentos das gestantes sobre a maternidade, com destaque para a relação entre o período gestacional e a constituição da maternidade. Participaram do estudo 39 gestantes primíparas, entre 19 e 37 anos, no terceiro trimestre de gestação. A análise de conteúdo qualitativa das entrevistas mostrou que as gestantes passaram por importantes transformações corporais, pessoais e interpessoais durante a gestação e vivenciaram intensos sentimentos em relação ao tornar-se mãe. Os achados sugerem que na gestação o processo de constituição da maternidade está em intenso desenvolvimento, assim como o próprio exercício ativo do papel materno.; Biological, somatic, psychological and social changes take place in pregnancy which influence the pregnant woman’s psychic dynamics and social relationships. The manner a woman experiences these changes impacts intensely on the constitution of motherhood and mother-infant relationships. Current study investigates pregnant women's feelings concerning motherhood...

The ESEP study: salpingostomy versus salpingectomy for tubal ectopic pregnancy; the impact on future fertility: A randomised controlled trial

Mol, F.; Strandell, A.; Jurkovic, D.; Yalcinkaya, T.; Verhoeve, H.; Koks, C.; van der Linden, P.; Graziosi, G.; Thurkow, A.; Hoek, A.; Hogstrom, L.; Klinte, I.; Nilsson, K.; van Mello, N.; Ankum, W.; van der Veen, F.; Mol, B.; Hajenius, P.
Fonte: BioMed Central Ltd. Publicador: BioMed Central Ltd.
Tipo: Artigo de Revista Científica
Publicado em //2008 EN
Relevância na Pesquisa
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BACKGROUND For most tubal ectopic pregnancies (EP) surgery is the treatment of first choice. Whether surgical treatment should be performed conservatively (salpingostomy) or radically (salpingectomy) in women wishing to preserve their reproductive capacity, is subject to debate. Salpingostomy preserves the tube, but bears the risks of both persistent trophoblast and repeat ipsilateral tubal EP. Salpingectomy, avoids these risks, but leaves only one tube for reproductive capacity. This study aims to reveal the trade-off between both surgical options: whether the potential advantage of salpingostomy, i.e. a better fertility prognosis as compared to salpingectomy, outweighs the potential disadvantages, i.e. persistent trophoblast and an increased risk for a repeat EP. METHODS/DESIGN International multi centre randomised controlled trial comparing salpingostomy versus salpingectomy in women with a tubal EP without contra lateral tubal pathology. Hemodynamically stable women with a presumptive diagnosis of tubal EP, scheduled for surgery, are eligible for inclusion. Patients pregnant after in vitro fertilisation (IVF) and/or known documented tubal pathology are excluded. At surgery, a tubal EP must be confirmed. Only women with a tubal EP amenable to both interventions and a healthy contra lateral tube are included. Salpingostomy and salpingectomy are performed according to standard procedures of participating hospitals. Up to 36 months after surgery...

The M-OVIN study: does switching treatment to FSH and / or IUI lead to higher pregnancy rates in a subset of women with world health organization type II anovulation not conceiving after six ovulatory cycles with clomiphene citrate - a randomised controlled trial

Nahuis, M.; Weiss, N.; van der Veen, F.; Mol, B.; Hompes, P.; Oosterhuis, G.; Lambalk, C.; Smeenk, J.; Koks, C.; van Golde, R.; Laven, J.; Cohlen, B.; Fleischer, K.; Goverde, A.; Gerards, M.; Klijn, N.; Nekrui, L.; van Rooij, I.; Hoozemans, D.; van Wely,
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Artigo de Revista Científica
Publicado em //2013 EN
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Background: Clomiphene citrate (CC) is first line treatment in women with World Health Organization (WHO) type II anovulation and polycystic ovary syndrome (PCOS). Whereas 60% to 85% of these women will ovulate on CC, only about one half will have conceived after six cycles. If women do not conceive, treatment can be continued with gonadotropins or intra-uterine insemination (IUI). At present, it is unclear for how many cycles ovulation induction with CC should be repeated, and when to switch to ovulation induction with gonadotropins and/or IUI. Methods/Design: We started a multicenter randomised controlled trial in the Netherlands comparing six cycles of CC plus intercourse or six cycles of gonadotrophins plus intercourse or six cycles of CC plus IUI or six cycles of gonadotrophins plus IUI. Women with WHO type II anovulation who ovulate but did not conceive after six ovulatory cycles of CC with a maximum of 150 mg daily for five days will be included. Our primary outcome is birth of a healthy child resulting from a pregnancy that was established in the first eight months after randomisation. Secondary outcomes are clinical pregnancy, miscarriage, multiple pregnancy and treatment costs. The analysis will be performed according to the intention to treat principle. Two comparisons will be made...

Fatores associados à gravidez em adolescentes brasileiros de baixa renda; Factores asociados al embarazo en adolescentes brasileños de baja renta; Factors associated with pregnancy among low-income Brazilian adolescents

Diniz, Eva; Koller, Silvia Helena
Fonte: Universidade de São Paulo. Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto Publicador: Universidade de São Paulo. Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; Formato: application/pdf
Publicado em 01/12/2012 POR
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This study aimed to assess factors associated with teen pregnancy among low-income Brazilian adolescents (N = 452) with pregnancy experience (n = 226) and without this experience (n = 226). The mean of age of the sample was 16.86 years old (SD = 1.35) and 64% were girls. A multivariate analysis demonstrated that teen pregnancy was associated with: living with the partner; use of oral contraception; lower age of the first sexual intercourse; use of alcoholic drinks; and lesser division of home chores. Teen pregnancy tends to appear when a conjugation of developmental risk variables exists. This information can be important with a view to interventions focused on this population, as well as for teen pregnancy prevention campaigns.; El presente artículo tiene como propósito investigar las características asociadas al embarazo durante la adolescencia en una población de adolescentes brasileños de baja renta (N = 452) con experiencia de embarazo (n = 226) y sin esta experiencia (n = 226). El promedio de edad de los participantes fue de 16,86 años (DE = 1,35) y el 64% era del sexo femenino. Resultados del análisis multivariado revelaron que el embarazo a lo largo de la adolescencia se asoció a: vivir con la pareja; utilización de la píldora anticonceptiva; inicio sexual precoz; consumo de bebidas alcohólicas; y menor división de tareas domésticas en la familia. El embarazo durante la adolescencia tiene tendencia a surgir ante un conjunto de variables que expresan la vulnerabilidad del contexto de desarrollo del adolescente. Esta podrá constituir una importante información para intervenciones dirigidas a la población afectada y un aporte a la prevención del embarazo durante la adolescencia.; Este estudo teve por objetivo investigar as características associadas à gravidez durante a adolescência em uma população de adolescentes brasileiros de baixa renda (N = 452) com experiência de gravidez (n = 226) e sem esta experiência (n = 226). A média de idade dos participantes foi de 16...

Serum markers in the diagnosis of tubal pregnancy

Cabar, Fabio Roberto; Fettback, Paula Beatriz; Pereira, Pedro Paulo; Zugaib, Marcelo
Fonte: Universidade de São Paulo. Faculdade de Medicina Publicador: Universidade de São Paulo. Faculdade de Medicina
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; Formato: application/pdf
Publicado em 01/01/2008 ENG
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The introduction of highly sensitive methods, such as transvaginal sonography and measurement of serum b-human chorionic gonadotropin, has dramatically improved ectopic pregnancy diagnosis in recent years. Early diagnosis is the key to successful and conservative management of women with ectopic pregnancy; however, approximately 50 percent of such women are initially misdiagnosed, resulting in significant morbidity and mortality. In order to improve diagnosis, several serum markers are being investigated including progesterone, CA 125, pregnancy-associated plasma protein-A, vascular endothelial growth factor, and maternal creatine kinase. Measurement of serum vascular endothelial growth factor, alone or together with other markers, could be a promising method for earlier and more accurate differential diagnosis. However, the clinical applicability of these findings remains to be evaluated in larger prospective studies.

Interrupção eletiva da gestação em cães (Canis familiaris, Linnaeus, 1758); Elective interruption of pregnancy in dogs (Canis familiaris, Linnaeus, 1758)

Brunckhorst, Claudia Stoll; Vuono, Laudinor de; Barnabe, Renato Camparanut
Fonte: Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia Publicador: Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; Formato: application/pdf
Publicado em 01/01/2000 POR
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Analisou-se a problemática da escolha de um método confiável e seguro para a interrupção eletiva da gestação em cadelas, prática comum em clínica de pequenos animais para a prevenção do nascimento de ninhadas indesejadas e fator importante não só na solução de problemas pessoais de proprietários, mas também no controle populacional da espécie. Foram abordados os aspectos favoráveis e contra-indicações da interrupção cirúrgica e medicamentosa da prenhez. A interrupção cirúrgica é considerada a melhor escolha para animais que não se pretenda utilizar para reprodução. A utilização de estrógenos, do citrato de tamoxifena e agentes embriotóxicos não-hormonais é restringida pelos seus graves efeitos colaterais. A epostana necessita maiores estudos para confirmar sua eficiência. Apesar de possível, o uso dos análogos de GnRH esbarra em limitações de fornecimento e custo, assim como o controle imunológico da gestação, na especificidade dos agentes utilizados e possíveis efeitos colaterais, enquanto o uso de glicocorticóides, na duração do tratamento e efeitos secundários inerentes aos corticosteróides. Mifepristona e aglepristona, indisponíveis no mercado, têm sido apontadas como drogas de futuro promissor em face de sua eficácia...

Estrogen and oxytocin receptors in the canine corpus luteum during pregnancy and parturition; Receptores de estrógeno e ocitocina no corpo lúteo durante a gestação e parto em cadelas

Veiga, Gisele Almeida Lima; Milazzotto, Marcella Pecora; Lúcio, Cristina Fátima; Silva, Liege Cristina Garcia; Vannucchi, Camila Infantosi
Fonte: Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia Publicador: Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; Formato: application/pdf
Publicado em 06/02/2015 ENG
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The expression of genes encoding the receptors for estrogen (ERαmRNA) and oxytocin (OTRmRNA) was studied in the corpus luteum during pregnancy and parturition in dogs. Real-time PCR was performed to quantify the levels of ERαmRNA and OTRmRNA in the corpus luteum of bitches during Early (up to 20 days of gestation), Mid (20 to 40 days) and Late Pregnancy (40 to 60 days), and Parturition (first stage of labor). The corpus luteum expressed mRNA for OTR, however ERα mRNA was not detected. There was a reduction of OTR mRNA expression in the corpus luteum from gestational Day 20 onward, which suggests an important role of OTR mRNA in the mechanism of pregnancy recognition in dogs. We concluded that the expression of OTR mRNA in canine corpus luteum vary over time, which support the idea that the sensitivity and response to hormone therapy can vary along the course of pregnancy and labor. Moreover, the canine CL lacks ERα mRNA expression during pregnancy. ; A expressão dos genes que codificam os receptores de estrógeno (REα RNAm) e ocitocina (ROT RNAm) foram estudados no corpo lúteo de cadelas durante a gestação e parto. A técnica de PCR em tempo real foi realizada para quantificar a expressão do REα RNAm e ROT RNAm no corpo lúteo de cadelas durante o início (até 20 dias de gestação)...

Influência do garanhão e da técnica de inseminação sobre os índices de recuperação embrionária e de gestação em um programa de transferência de embriões em eqüinos da raça Mangalarga; Influence of stallion and insemination technique on embryo recovery rates and pregnancy in a program of embryos transfer in equine Mangalarga breed

Fleury, João Junqueira; Pinto, Abílio Junqueira; Celeghini, Eneiva Carla Carvalho; Lima, César Gonçalves; Arruda, Rubens Paes de
Fonte: Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia Publicador: Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; Formato: application/pdf
Publicado em 01/01/2001 POR
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Muitos fatores podem afetar as taxas de gestação após a transferência de embriões em eqüinos. Este estudo teve como objetivo avaliar, em eqüinos da raça Mangalarga e em duas estações reprodutivas, a influência do garanhão e de três diferentes técnicas de inseminação (monta natural, inseminação artificial com sêmen diluído fresco ou resfriado) sobre os índices de recuperação de embriões e de prenhez. No primeiro ano, foram encontradas diferenças significativas (p < 0,05) na recuperação de embriões entre cinco garanhões estudados (28,6; 65,0; 62,9; 66,7 e 84,2%), mas não foram encontradas diferenças significativas (p >; 0,05) nos índices de prenhez (50,0; 80,7; 70,6; 70,0 e 62,5%). No segundo ano, verificou-se uma tendência à significância (p = 0,057), na recuperação de embriões entre quatro garanhões estudados (44,4; 56,2; 71,4 e 73,7%) e não houve diferença significativa (p >; 0,05) nos índices de prenhez (75,0; 55,6; 86,7 e 71,4%). Não houve diferença significativa (p >; 0,05) nos índices de embriões recuperados e de prenhez comparando-se a monta natural (50,0 e 87,5%) e a inseminação artificial com sêmen fresco (60,6 e 73,7%) ou refrigerado (63,8 e 80,3%).; Many factors can affect pregnancy rates after equine embryo transfer. This study had the objective of evaluating the influence of stallion and of three different insemination techniques (natural breed...

Weight loss in pregnancy and cardiometabolic profile in childhood: findings from a longitudinal birth cohort

Grooten, I.; Painter, R.; Pontesilli, M.; van der Post, J.; Mol, B.; van Eijsden, M.; Vrijkotte, T.; Roseboom, T.
Fonte: Wiley Publicador: Wiley
Tipo: Artigo de Revista Científica
Publicado em //2014 EN
Relevância na Pesquisa
36.45%
To investigate the consequences of weight loss in pregnancy on pregnancy outcomes and cardiometabolic profile in childhood.Prospective birth cohort (ABCD study).Between 2003 and 2004, all pregnant women in Amsterdam were approached for study participation.7818 pregnant women were included, of which 3165 consented to having their children examined at 5-6 years of age. In 1956 children fasting capillary blood samples were also taken.At antenatal booking, women answered questions about their pregnancy and whether they suffered from severe weight loss (SWL; >5 kg). Pregnancy details and outcomes were available through the obstetric caregiver.At birth main outcome measures were prematurity (<37 weeks) and birthweight. At follow-up, body mass index (BMI), blood pressure, glucose and lipids were assessed.SWL occurred in 6.8% of cases. Women with SWL had similar preterm birth rates compared with women without these complaints (adjusted OR 1.1, 95%CI 0.7, 1.7). Birthweight (adjusted difference - 31 g, 95%CI -76, 15) and BMI at 5-6 years of age (adjusted difference 0.2 kg/m(2) , 95%CI 0.0, 0.5) were similar in children born to mothers with SWL and without SWL, but blood pressure was increased. For diastolic blood pressure this association was independent of confounders (adjusted difference 1.4 mmHg...

"My midwife said that having a glass of red wine was actually better for the baby": a focus group study of women and their partner's knowledge and experiences relating to alcohol consumption in pregnancy

Crawford-Williams, F.; Steen, M.; Esterman, A.; Fielder, A.; Mikocka-Walus, A.
Fonte: BioMed Central Publicador: BioMed Central
Tipo: Artigo de Revista Científica
Publicado em //2015 EN
Relevância na Pesquisa
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BACKGROUND: While it is well established that alcohol can cross the placenta to the foetus and can affect an infant's development, many women continue to drink during pregnancy. For this reason it is important to determine what information is being provided, what information may be missing, and the preferred sources of information on this issue. In order to improve prevention strategies, we sought to understand the knowledge and experiences of pregnant women and their partners regarding the effects of alcohol consumption during pregnancy. METHODS: The current study utilised a qualitative study design in order to gain insight into the views and experiences of pregnant women, newly delivered mothers and their partners. Focus groups examined the participant's knowledge about the effects of alcohol consumption during pregnancy, the sources of information on this issue, and the psycho-social influences on their drinking behaviour. Five focus groups were conducted involving a total of 21 participants (17 female). A six-stage thematic analysis framework was used to analyse all focus group discussions in a systematic way. RESULTS: Seven major themes were identified from the focus group data: 1) knowledge of Foetal Alcohol Spectrum Disorders; 2) message content and sources; 3) healthcare system; 4) society and culture; 5) partner role; 6) evaluation of risk; and 7) motivation. The findings indicated that although the majority of participants knew not to drink alcohol in pregnancy they had limited information on the specific harmful effects. In addition...

Características da gravidez na adolescência em São Luís, Maranhão; Characteristics of adolescent pregnancy, Brazil

Simões, Vanda Maria Ferreira; Silva, Antônio Augusto Moura da; Bettiol, Heloisa; Lamy-Filho, Fernando; Tonial, Sueli Rosina; Mochel, Elba Gomide
Fonte: Universidade de São Paulo. Faculdade de Saúde Pública Publicador: Universidade de São Paulo. Faculdade de Saúde Pública
Tipo: info:eu-repo/semantics/article; info:eu-repo/semantics/publishedVersion; ; ; ; ; Formato: application/pdf
Publicado em 01/10/2003 POR
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OBJETIVO: Identificar as principais características socioeconômicas, demográficas, antropométricas e comportamentais, bem como os resultados perinatais da gravidez na adolescência. Conhecer os tipos de serviços de saúde utilizados pelas gestantes adolescentes. MÉTODOS: A amostra de 2.429 partos de mulheres residentes em São Luís, MA, abrangeu 94% dos nascimentos hospitalares. As mulheres foram separadas em seis grupos de idade para melhor avaliação do comportamento das variáveis entre os dois grupos de adolescentes (abaixo de 18 anos; 18 a 19 anos) e entre as adolescentes e as demais mulheres. O teste do qui-quadrado foi utilizado para a comparação de proporções e a razão de prevalências foi empregada como medida de efeito. RESULTADOS: Das 2.429 mulheres, 714 eram adolescentes (29,4%). Seu coeficiente específico de fecundidade, 72,2 por mil, foi mais elevado que em outras regiões do País. As adolescentes apresentaram piores condições socioeconômicas e reprodutivas que as demais mulheres, maior proporção de pré-natal inadequado (39,2%) e muitas não tinham companheiro (34,5%). Por outro lado, tiveram menor proporção de parto cesáreo (23,0%) e de fumantes (3.5%). CONCLUSÕES: Apesar da situação socioeconômica igualmente desfavorável...

Prevalence and persistence of nausea and vomiting along the pregnancy

Coronado,Pluvio J.; Fasero,María; Álvarez-Sánchez,Ángel; Rey,Enrique
Fonte: Revista Española de Enfermedades Digestivas Publicador: Revista Española de Enfermedades Digestivas
Tipo: info:eu-repo/semantics/article; journal article; info:eu-repo/semantics/publishedVersion Formato: text/html; application/pdf
Publicado em 01/05/2014 ENG
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Background/aims: Nausea and vomiting of pregnancy (NVP) impact in the pregnant woman's quality of life, especially when are persistent or severe. The objective is to estimate the prevalence and factors associated with the persistence of NVP in each trimester of pregnancy. Methods: We studied a cohort of 263 pregnant women with gestational age < 12 weeks. Data were collected using the Gastro-Esophageal Reflux Questionnaire validated for use in the Spanish population. Data were collected through telephone interviews at the end of each trimester of pregnancy. The main variable was the presence of NVP in each trimester and their persistence along the pregnancy. Results: The prevalence of nausea in the each trimester was 63.5 %, 33.8 %, 26.2 %, and vomiting was 29.3 %, 22.1 %, 14.1 %, respectively. Factors associated with nausea in the first trimester were Latin-American origin (OR: 3.60, 95 %IC 1.61-80.5) and primary education (OR: 0.31; 0.13-0.73); vomiting was associated with Latin-American origin (OR: 13.80, 1.82-104.4) and was inversely associated with weight gain (OR: 0.58, 0.35-0.97). Persistence of NVP were only associated with suffering the symptom in the previous trimester (p < 0.01), and did not find other predictor factors. Conclusions: NVP's prevalence declines along pregnancy...

High dietary calcium intake decreases bone mobilization during pregnancy in humans

Avendaño-Badillo,Diana; Hernández-Ávila,Mauricio; Hernández-Cadena,Leticia; Rueda-Hernández,Gabriela; Solano-González,Maritsa; Ibarra,Luis G; Hu,Howard; Téllez-Rojo,Martha M.
Fonte: Instituto Nacional de Salud Pública Publicador: Instituto Nacional de Salud Pública
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/01/2009 EN
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Calcium metabolism of the mother is modified during pregnancy because of the mineralization of the fetus skeleton. OBJECTIVE: To evaluate the association of calcium intake and bone demineralization during pregnancy. MATERIAL AND METHODS: At each trimester of pregnancy a validated food frequency intake questionnaire was administered to assess individual daily calcium intake in a cohort of 206 pregnant women, residents of Mexico City. Samples of urine were collected to measure levels of the cross-linked N-telopeptide of type I collagen (NTx), which is a biomarker of bone resorption. The association between calcium ingestion and bone resorption was analyzed using random effects models; non-linear associations were explored using generalized additive models. RESULTS: Progressive increases in NTx levels were observed during pregnancy; with mean and standard deviation (SD) values during the first, second and third trimester of 76.50 (SD=38), 101.02 (SD=48.86) and 144.83 (SD=61.33) nmol BCE/mmol creatinine, respectively. Higher dietary calcium intake was associated with lower bone resorption (β=-0.015; p<0.05). The association between age and NTx showed a non-linear trend with an inflexion point around 33 years: increase in maternal age below that point was associated with a decrease in bone resorption...

Brief communication: Effect of post-mating progestagen administration on pregnancy rate in crossbred goats following an induced estrus

Nava-Trujillo,Héctor; Chango-Villasmil,José; Finol-Parra,Geovanny; Maldonado-Suárez,Juan; Torres-Rodríguez,Paola; Carrillo-Fernández,Freygelinne; Gil-Huerta,Lidya; González,Noelia
Fonte: UNIVERSIDAD DEL ZULIA Publicador: UNIVERSIDAD DEL ZULIA
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/10/2008 EN
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Estrus induced with progesterone or progestagens have low fertility compared to natural estrus. However, post-mating progesterone administration has been reported by increases embryo development and pregnancy rate; therefore the aim of this study was to evaluate the effect of post-mating progestagen administration on pregnancy rate after medroxyprogesterone acetate (MAP) induced estrus in crossbred goats. Estrus induction was started at 31.3 ± 1.7 days post-partum with intra- vaginal sponges impregnated with 60 mg of MAP during 14 days and at time of sponge removal were applied 500 IU of eCG intramuscular. Estrus was detected every 6 hours from 24 hours onwards after sponge withdrawal. Goats were naturally mated with two entry bucks. Five days post-mating, mated goats were randomly assorted into two groups, control group (n=18), without any treatment, and MAP group (n=18), receiving a sponge with 60 mg of MAP for fourteen days. Ultrasonographyc diagnosis of pregnancy was performed at day 50 post-mating. MAP treatment, did not affect the pregnancy rate, with 44.4% (8/18) in MAP group, while in control group was 55.5% (10/18), P>0.05. In conclusion, MAP treatment with a sponge impregnated with 60 mg of MAP between days 5 and 19 post-mating did not affect the pregnancy rate after progestagen induced estrus during the early post-partum period in crossbred tropical goats.

Embryo transfer in angus and brahman recipient cows: Effect of two methods of estrus synchronization on induced estrus and pregnancy

Chase, Jr,Chad C; Vargas,Carlos A; Hammond,Andrew C; Olson,Timothy A; Griffin,James L; Murphy,Clifton N; Tewolde,Assefaw; Fields,Michael J
Fonte: UNIVERSIDAD DEL ZULIA Publicador: UNIVERSIDAD DEL ZULIA
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/12/2009 EN
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36.45%
Over a 3-year period, 88 Angus and 87 Brahman cows were used as recipients to determine the effects of breedtype and method of estrous synchronization on induced estrus and subsequent pregnancy following embryo transfer. Estrus was synchronized in recipients using either prostaglandin-F2α (PGF; Lutalyse) or progestogen (PRO; Syncro-Mate-B). Recipients were treated (im) with PGF on day -11 (25 mg), 0 (12.5 mg), and 1 (12.5 mg). Recipients were treated with PRO on day -9 (6 mg norgestomet ear implant and 2 mL [im] of 3 mg of norgestomet and 5 mg of estradiol valerate) and the ear implant was removed on day 0. Embryos were randomly transferred to recipients synchronous +24 to -24 h with a 7-d embryo. Both synchronization methods (PGF vs. PRO) were similarly effective in inducing estrus (89.8 vs. 86.7%). Percentage of induced estrus was similar between Brahman (91.0%) and Angus (85.6%). Recipients treated with PGF had a longer (P = 0.001) interval to estrus than PRO treated recipients (77.4 vs. 60.1 h). Estrus response in Angus was earlier (P = 0.043) than in Brahman (65.4 vs. 72.2 h). Neither breed (P = 0.97; Angus 49% 35/72 and Brahman 54% 38/70) nor estrus synchronization treatment (P = 0.23; PRO 49% 35/72 and PGF 54% 38/70) affected pregnancy rate. Pregnancy rates in recipients closely synchronized (0 h) was 60.0%...

Prevalence of anemia during pregnancy: Results of Valencia (Venezuela) anemia during pregnancy study

Martí-Carvaja,Arturo; Peña-Martí,Guiomar; Comunian,Gabriela; Muñoz,Sergio
Fonte: Sociedad Latinoamericana de Nutrición Publicador: Sociedad Latinoamericana de Nutrición
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/03/2002 EN
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To determine the prevalence of anemia during pregnancy in Venezuelan pregnant women. By using a cross-sectional study, 630 Venezuelan pregnant women in their third trimester at labor from the Valencia Anemia during Pregnancy Study were studied. Anemia during pregnancy was defined according to WHO guidelines (Hb < 11g/dl), iron deficiency was considered when serum ferritin level was < 12 ng/ml, and when serum folate level was < 3ng/ml, it was considered as folate deficiency. 630 pregnant women (mean [± SD] age, 24± 6.4 years) having an average of Hb 11.38±1.47 g/dl [95%CI = 11.27 to 11.50] were studied. No patient had hemolytic anemia nor clinical infections. Almost all patients were from low or very low socioeconomic status. Prevalence of anemia was 34.44% (severe: 1.8%, moderate: 15.2%, and mild: 83%). Iron deficiency anemia (IDA) was present in 39.2% (95%CI= 32.7 to 45.7), prevalence of folate deficiency anemia (FDA) was 11.98% (95%CI = 7.6% to 16.3%). Combined anemia (IDA and FDA) occurred in 11.52% (95%CI= 7.27% to 15.7%). Multivariate analysis showed that multiparous (odds ratio -OR-: 1.95, 95%CI= 1.28 to 2.97, p =.002) and supplement use of iron (OR: .55 (95%CI= .33 to .91 , p= .02) are associated with IDA. The factors associated with FDA were: supplement use of folic acid (OR: .37 (95%CI=.19 to .71 ...

Calabash pregnancy: a malingering response to infertility complicated by domestic violence

Adesiyun,AG; Ameh,N; Bawa,U; Adamu,H; Kolawole,A
Fonte: West Indian Medical Journal Publicador: West Indian Medical Journal
Tipo: Artigo de Revista Científica Formato: text/html
Publicado em 01/03/2012 EN
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This is a case report of a 20-year old para 0+0 who presented with an 11-month pregnancy. On evaluation, the pregnancy was found to be a fake made-up 'calabash pregnancy There were no pregnancy symptoms and she had just menstruated three weeks prior to presentation. This was a deliberate event in response to delayed pregnancy attainment complicated by domestic violence. Domestic violence was in the form of verbal and physical abuse and later was on a monthly basis precipitated by onset of her menstrual flow. The patient's age, monogamous union and the fact that she is an orphan made her vulnerable to domestic violence.