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Atypical localizations of calcific deposits in the shoulder

Vinanti, G.B.; Pavan, D.; Rossato, A.; Biz, Carlo
Fonte: Elsevier Publicador: Elsevier
Tipo: Artigo de Revista Científica
Publicado em 08/04/2015 EN
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•Case 1: massive calcific deposits in the context of the supraspinatus muscle belly.•Case 2: calcific deposits at the biceps anchor.•Case 3: calcific deposits in the cranial intra-articular trait of the subscapularis tendon.•These 3 atypical cases were not responsive to conservative treatment.•Arthroscopic removal of the deposits ensured an optimal clinical outcome.

Amyloid deposits: Protection against toxic protein species?

Treusch, Sebastian; Cyr, Douglas M.; Lindquist, Susan
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
EN
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Neurodegenerative diseases ranging from Alzheimer disease and polyglutamine diseases to transmissible spongiform encephalopathies are associated with the aggregation and accumulation of misfolded proteins. In several cases the intracellular and extracellular protein deposits contain a fibrillar protein species called amyloid. However while amyloid deposits are hallmarks of numerous neurodegenerative diseases, their actual role in disease progression remains unclear. Especially perplexing is the often poor correlation between these deposits and other markers of neurodegeneration. As a result the question remains whether amyloid deposits are the disease-causing species, the consequence of cellular disease pathology or even the result of a protective cellular response to misfolded protein species. Here we highlight studies that suggest that accumulation and sequestration of misfolded protein in amyloid inclusion bodies and plaques can serve a protective function. Furthermore, we discuss how exceeding the cellular capacity for protective deposition of misfolded proteins may contribute to the formation of toxic protein species.

Post-depositional fracturing and subsidence of pumice flow deposits: Lascar Volcano, Chile

Whelley, Patrick L.; Jay, J.; Calder, E. S.; Pritchard, M. E.; Cassidy, N. J.; Alcaraz, S.; Pavez, A.
Fonte: Springer-Verlag Publicador: Springer-Verlag
Tipo: Artigo de Revista Científica
EN
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Unconsolidated pyroclastic flow deposits of the 1993 eruption of Lascar Volcano, Chile, have, with time, become increasingly dissected by a network of deeply penetrating fractures. The fracture network comprises orthogonal sets of decimeter-wide linear voids that form a pseudo-polygonal grid visible on the deposit surface. In this work, we combine shallow surface geophysical imaging tools with remote sensing observations and direct field measurements of the deposit to investigate these fractures and their underlying causal mechanisms. Based on ground penetrating radar images, the fractures are observed to have propagated to depths of up to 10 m. In addition, orbiting radar interferometry shows that deposit subsidence of up to 1 cm/year−1 occurred between 1993 and 1996 with continued subsidence occurring at a slower rate thereafter. In situ measurements show that 1 m below the surface, the 1993 deposits remain 5°C to 15°C hotter, 18 years after emplacement, than adjacent deposits. Based on the observed subsidence as well as estimated cooling rates, the fractures are inferred to be the combined result of deaeration, thermal contraction, and sedimentary compaction in the months to years following deposition. Significant environmental factors...

Videotaping the Response of the Melon Aphid (Homoptera: Aphididae) to Bifenthrin Spray Deposits on Chrysanthemums

Adams, Andrew J.; Hall, Franklin R.; Lindquist, Richard K.; Rolph, Ian A.; Adams, Isabelle H. H.
Fonte: Oxford University Press Publicador: Oxford University Press
Tipo: Artigo de Revista Científica Formato: text/html
EN
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Melon aphids, Aphis gossypii Glover, were videotaped as they walked across a leaf surface that had been sprayed with uniformly sized aqueous droplets of bifenthrin. Videotape recordings showed that the frequency with which aphids encountered droplet deposits was directly related to the droplet density (droplets per cm2). When the aphids were exposed to sparse deposits (5 drops per cm2 or 2.5 per cm2, 120-μm droplet in-flight diameter) irritation was apparent before physical contact with deposits, suggesting the existence of a localized vapor effect. Physical contact with deposits was not a necessary prerequisite for acquiring a lethal dose.

INVESTIGATION OF THE ISOTOPIC SIGNATURE OF THE VAZANTE AND NORTHERN EXTENSION ZINC SILICATE DEPOSITS, MINAS GERAIS, BRAZIL

Percy, Emma L.
Fonte: Quens University Publicador: Quens University
Tipo: Tese de Doutorado
EN
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There has been renewed interest in zinc silicate deposits because of their high grade and the development of economic processing methods, but the genetic model for zinc silicate deposits is still poorly understood. The largest structurally controlled hypogene zinc silicate deposits in the world occur in the Neoproterozoic Vazante Group in Minas Gerais, Brazil. They are the Vazante deposit (18Mt at 19% Zn) and the Vazante Northern Extension orebody (850kt at 16% Zn), where willemite (Zn2SiO4) is the main zinc ore. The Vazante Group also contains a number of carbonate hosted Pb-Zn sulfide deposits (e.g. Morro Agudo and Ambrósia) and occurrences. The Vazante zinc silicate orebodies occur in the dolomitic rocks of the Serra do Poço Verde Formation that were deposited in an intertidal to supratidal environment. A NE-trending fault zone structurally controls the ore in the Vazante Mine and Northern Extension and mineralization occurs in major tectonic-hydrothermal breccias formed during the Brasiliano Orogeny. Willemite occurs in hydrothermal breccias that contain hematite, quartz, Fe-dolomite, dolomite and minor franklinite, magnetite and sphalerite. In the Northern Extension ore zone the pre-ore stage involved the brecciation of host rocks and the precipitation of Fe-dolomite. Early hematite occurs as replacement zones throughout some of the altered Fe-dolomite. Willemite replaces dolomite in breccia clasts...

Bank Activity and Funding Strategies : The Impact on Risk and Returns

Demirgüç-Kunt, Asli; Huizinga, Harry
Fonte: Banco Mundial Publicador: Banco Mundial
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This paper examines the implications of bank activity and short-term funding strategies for bank risk and returns using an international sample of 1,334 banks in 101 countries leading up to the 2007 financial crisis. Expansion into non-interest income generating activities such as trading increases the rate of return on assets, and it may offer some risk diversification benefits at very low levels. Non-deposit, wholesale funding, by contrast, lowers the rate of return on assets, although it can offer some risk reduction at commonly observed low levels of non-deposit funding. A sizeable proportion of banks, however, attract most of their short-term funding in the form of non-deposits at a cost of enhanced bank fragility. Overall, banking strategies that rely prominently on generating non-interest income or attracting non-deposit funding are very risky, which is consistent with the demise of the U.S. investment banking sector.

The Afghanistan Mining Sector as a Driver of Sustainable Growth : Benefits and Opportunities for Large-Scale Mining

World Bank
Fonte: Washington, DC Publicador: Washington, DC
EN_US
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This study attempts to quantify the benefits that could be obtained for the country of Afghanistan from the developments of the Aynak copper and Hajigak iron ore deposits and to discuss policies and programs-based on the experience of other countries-that will tend to maximize the benefits from these and other mines. In this study, the potential economic benefits to Afghanistan of its mining sector will be analyzed, focusing on the Aynak copper and Hajigak iron ore deposits. After an overview of the Afghan mineral industry and global trends in mining, a quantitative analysis will be made of the economic contribution of the development of these deposits and related infrastructure for income and employment in Afghanistan. Various scenarios will be presented as well as sensitivity analysis of key parameters. The analysis will focus on income, fiscal revenues, employment, sidestream linkages (sourcing), and the multiplier effects of expenditure by both the government and consumers. In the Afghanistan context...

Financial Access 2009 : Measuring Access to Financial Services around the World

Consultative Group to Assist the Poor
Fonte: Consultative Group to Assist the Poor/The World Bank, Washington, DC Publicador: Consultative Group to Assist the Poor/The World Bank, Washington, DC
EN_US
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Financial Access 2009 introduces the latest data from a survey of financial regulators in 139 countries. It presents indicators of access to savings, credit, and payment services in banks, and in regulated nonbank financial institutions. It is intended for a broad audience of policymakers, researchers, practitioners, multilateral and bilateral investors, in order to guide monetary policy, monitor systemic risks, and collect information on the values of deposits and credit. This report reviews three interventions: disclosure requirements, interest rate caps, and methods to address excessive lending that can result in consumer indebtedness. Improved transparency and disclosure allow borrowers to make informed choices and can facilitate competition in financial markets, eventually leading to lower prices and improved products. Policies to restrict interest rates or credit quantity, especially in consumer credit, seem to have limited effect but require further analysis.

Cretaceous marine reptiles of Australia: a review of taxonomy and distribution

Kear, Benjamin Philip
Fonte: Academic Press Limited Publicador: Academic Press Limited
Tipo: Artigo de Revista Científica
Publicado em //2003 EN
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Marine reptile fossils are common in the Cretaceous epicontinental and continental-margin marine deposits of Australia but much of the material is sparsely documented. A review of current localities indicates that the majority of remains are known from the Aptian–Albian epicontinental marine units of the Eromanga Basin in Queensland, New South Wales and South Australia. Fragmentary specimens have also been recovered from Berriasian, Hauterivian–Barremian, Albian–Cenomanian, Cenomanian–Turonian and Maastrichtian marine deposits of Western Australia, Aptian or Albian continental margin rocks of the Northern Territory and Aptian–Albian freshwater sediments of New South Wales and Victoria. Interestingly, many of these deposits represent Cretaceous high latitude-polar environments and some include palaeoclimatic indicators suggesting very cold to near freezing conditions. As currently known, the Australian Cretaceous marine reptile fauna comprises one family of ichthyosaurs (Ophthalmosauridae), as many as five families of plesiosaur (Rhomaleosauridae, Pliosauridae, Polycotylidae, Elasmosauridae and possibly Cryptoclididae or Cimoliasauridae sensu Acta Zool. Fenn. 213 (2001)), one family of chelonioid sea turtle (Protostegidae) and indeterminate mosasaurids. Although few named Australian species may be regarded as valid...

Revaporisation of fission product deposits in the primary circuit and its impact on accident source term

BOTTOMLEY Paul; KNEBEL KEVIN; VAN WINCKEL Stefaan; HASTE Tim; SOUVI Sidi; AUVINEN Ari; KALILAINEN J.; KÄRKELÄ Teemu
Fonte: PERGAMON-ELSEVIER SCIENCE LTD Publicador: PERGAMON-ELSEVIER SCIENCE LTD
Tipo: Articles in Journals Formato: Online
ENG
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Chemical revaporisation or physical resuspension of fission product deposits from the primary circuit is now recognised to be a major source term in the late phase of severe fuel degradation in a severe nuclear accident. These results come from tests carried out under different experimental projects in the European Commission (EC) Framework Programmes. These include the revaporisation tests carried out at the Transuranium Institute (ITU), Karlsruhe under the Fourth Framework Programme, the Phébus FP post-test analysis programme that examined FPT1, FPT3 and FPT4 deposits in separate-effect tests as well as EXSI-PC tests carried out at VTT, Espoo. The first tests at ITU and VTT concentrated on the behaviour of caesium as a very important fission product; this has helped detailed interpretation of the integral Phébus FP tests and has clarified some puzzling observations. Testing with Phébus FPT1 and FPT4 deposits at ITU demonstrated that revaporisation is a likely, rather than a possible, phenomenon with a severely degrading bundle. They have also shown that any changes in temperature (substrate or gas), flow rate or atmosphere composition or pressure can lead to the volatilisation or removal of the deposited caesium. Cs was particularly easy to follow given the high activity levels of Cs in the deposit. However further analysis of the deposits shows that other fission products are also subject to revaporisation. In the most recent FPT3 test...

Sedimentary geology of glacial and periglacial gravel bodies (SW-Germany) : Dynamic stratigraphy and aquifer-sedimentology

Heinz, Jürgen
Fonte: Universität Tübingen Publicador: Universität Tübingen
Tipo: Buch (Monographie); info:eu-repo/semantics/book
EN
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Würmian, coarse-grained meltwater deposits were studied in more than 70 gravel pits of SW-Germany. The heterogeneity + complexity of sedimentary architecture of gravel bodies + its distribution within the Rhine glacier area + its discharge zones required the use of sedimentological, stratigraphic, geophysical + hydrological methods. In order to understand the processes of formation the principles of ‘Dynamic Stratigraphy' were applied. Stratigraphic units were classified into a hierarchy of temporal + spatial scales (1. particles; 2. strata; 3. depositional elements; 4. facies bodies; 5. sequences; 6. basin fills). Their genesis + geophysical record but also their relevance for hydrogeology is discussed. A particular focus is placed on the qual. + quant. characterization of fluvial gravel-bed deposits which represent important groundwater storages in many valley fills in Europe. The translation of sedimentary units into hydrogeological properties (lithofacies - hydrofacies; depositional elements - correlation structures; gravel body architectures - heterogeneity patterns) provided important fluid-flow parameters. Detailed outcrop-wall maps were digitalized + transformed into 2-dimensional permeability fields. The simulations show how sedimentary architectures determine the flow-paths + -velocity of groundwater. 3-D georadar surveys were carried out. The method resolves a detailed structural image of the spatial subsurface architecture and allows the recognition of the different gravel bodies. Quantified geometrical data from both braided river deposits + meandering river deposits are documented. Various meltwater-controlled facies bodies were formed during an overall ice-retreat of the Würmian Rhine glacier. A summary of lithofacies types...

A deposition mechanism for Holocene miring bone deposits, South Island, New Zealand

Wood, J.; Worthy, T.; Rawlence, N.; Jones, S.; Read, S.
Fonte: Palaeontological Network Foundation Publicador: Palaeontological Network Foundation
Tipo: Artigo de Revista Científica
Publicado em //2008 EN
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Localised deposits of Late Pleistocene and Holocene bird bones occur in wetlands throughout New Zealand. These are characterised by dense accumulations of mostly disarticulated bones, with assemblages dominated by large, flightless bird taxa; in particular the extinct ratite moa (Aves: Dinornithiformes). A wide range of deposition mechanisms were historically proposed for these sites, including large floods and stampedes during wildfires. We outline a simple method for analysing the orientation and spatial distribution of bones within these deposits using GIS software, and apply this method to the interpretation of three such deposits from South Island, New Zealand. The results are consistent with non-catastrophic, periodic miring of individual moa. Long bones within these sites were preferentially orientated and subhorizontally inclined, indicating post-deposition disarticulation and movement of the bones within the sediment by sediment liquefaction and raking from the legs of mired birds, with a possible influence from water flow. Small, light skeletal elements were significantly under represented in the deposits. This may be due to post-mortem scavenging or weathering of vertebra and crania, 'pumping' to the surface of light, buoyant elements during liquefaction events...

Comparative Review of Microfinance Regulatory Framework Issues in Benin, Ghana, and Tanzania

Gallardo, Joselito; Ouattara, Korotoumou; Randhawa, Bikki; Steel, William F.
Fonte: World Bank, Washington, DC Publicador: World Bank, Washington, DC
Tipo: Publications & Research :: Policy Research Working Paper; Publications & Research
ENGLISH
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The authors investigate the microfinance regulatory regimes in Benin, Ghana, and Tanzania, with a view to identifying key issues and lessons on how the overall regulatory framework affects integration of microfinance institutions into the financial system. The authors find that recognizing different tiers of both regulated and unregulated institutions in a financial structure facilitates financial deepening and outreach to otherwise underserved groups in urban and rural areas. That environment promotes sustainable microfinance under shared performance standards and encourages regulatory authorities to develop appropriate prudential regulations and staff capacity. Case studies of the three countries raise important issues on promoting microfinance development vis-à-vis regulating them. Laws to regulate activities other than intermediation of public deposits into loans can result in disproportionately restrictive and unmanageable standards, even as dynamic microfinance sectors have emerged without conducive regulatory regimes. The authors use the three countries' regulatory experiences to highlight the importance of differentiating when prudential supervision is warranted and when regulatory oversight suffices, and to identify the agencies to carry out regulation. They address an important issue that has received scant attention...

Financial Sector Assessment : Republic of Tajikistan

World Bank
Fonte: World Bank Publicador: World Bank
Tipo: Economic & Sector Work :: Financial Sector Assessment Program (FSAP)
ENGLISH
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Financial intermediation in Tajikistan has deepened in recent years, albeit from a low base. This is reflected in the overall growth of the financial system, greater diversification, and the expansion of lending to previously under-served sectors, such as agriculture and small- and medium-sized enterprises. Even after the expansion, however, the financial sector remains small and cannot serve all the financing needs of the economy. While banks are generally well capitalized and liquid, their rapid growth has brought new risk exposures that should be carefully monitored and appropriately addressed. In particular, rapid loan growth could lead to a build-up of unrecognized credit risk and give rise to an increase in non-performing loans (NPLs). Because of extensive dollarization, the exposure of banks to exchange-rate induced credit risk is another significant cause for concern. Also, the exceptionally rapid growth of nonresident deposits without clear knowledge of their sources exposes the banking system to reputational risk. Significant strengthening of the regulatory and supervisory framework will be needed to sustain the system's health in the face of rapid growth. Governance in the financial sector needs significant strengthening. Improvements are needed to ensure the integrity of the regulatory bodies and to guarantee that all financial transactions are conducted at arms' length and priced on a market basis. Fair and transparent resolution of the large stock of distressed cotton debt would demonstrate the government's commitment to market principles and good governance.

Protein A-gold immunoelectron microscopic study of amyloid fibrils, granular deposits, and fibrillar luminal aggregates in renal amyloidosis.

Yang, G. C.; Gallo, G. R.
Fonte: PubMed Publicador: PubMed
Tipo: Artigo de Revista Científica
Publicado em /11/1990 EN
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26.66%
Glomeruli of archival renal biopsies, stored frozen at -70 degrees C, from three patients with amyloid were examined by protein A-gold immunoelectron microscopy. In one with both fibrillar and granular deposits from a 'skin popper' drug abuser, the granular deposits were labeled with anti-IgG, while the fibrillar deposits were labeled with anti-amyloid-A (AA) protein and amyloid P component (AP), suggesting coexisting immune complex disease and AA due to different, but possibly related, pathogenesis. In studies using double-label immunostaining of primary amyloidosis-lambda light chain type (AL) and AA associated with Crohn's disease, AP occurred as widely separated single units along the amyloid fibrils and represented 1.5% and 6.5% of the total gold label in AL and AA, respectively, while the major fibril protein was labeled in single rows, similar to beads on a string. Fibrillar aggregates in the capillary lumens were labeled similarly by antisera to the major protein and AP and appeared to be contiguous with the fibrillar deposits at the glomerular basement membrane (GBM)-luminal interface, suggesting intravascular fibrillogenesis.

In Vivo Detection of Amyloid-β Deposits Using Heavy Chain Antibody Fragments in a Transgenic Mouse Model for Alzheimer's Disease

Nabuurs, Rob J. A.; Rutgers, Kim S.; Welling, Mick M.; Metaxas, Athanasios; de Backer, Maaike E.; Rotman, Maarten; Bacskai, Brian J.; van Buchem, Mark A.; van der Maarel, Silvère M.; van der Weerd, Louise
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
Publicado em 04/06/2012 EN
Relevância na Pesquisa
26.66%
This study investigated the in vivo properties of two heavy chain antibody fragments (VHH), ni3A and pa2H, to differentially detect vascular or parenchymal amyloid-β deposits characteristic for Alzheimer's disease and cerebral amyloid angiopathy. Blood clearance and biodistribution including brain uptake were assessed by bolus injection of radiolabeled VHH in APP/PS1 mice or wildtype littermates. In addition, in vivo specificity for Aβ was examined in more detail with fluorescently labeled VHH by circumventing the blood-brain barrier via direct application or intracarotid co-injection with mannitol. All VHH showed rapid renal clearance (10–20 min). Twenty-four hours post-injection 99mTc-pa2H resulted in a small yet significant higher cerebral uptake in the APP/PS1 animals. No difference in brain uptake were observed for 99mTc-ni3A or DTPA(111In)-pa2H, which lacked additional peptide tags to investigate further clinical applicability. In vivo specificity for Aβ was confirmed for both fluorescently labeled VHH, where pa2H remained readily detectable for 24 hours or more after injection. Furthermore, both VHH showed affinity for parenchymal and vascular deposits, this in contrast to human tissue, where ni3A specifically targeted only vascular Aβ. Despite a brain uptake that is as yet too low for in vivo imaging...

Pliocene lahar deposits in the Coastal Cordillera of central Chile: Implications for uplift, avalanche deposits, and porphyry copper systems in the Main Andean Cordillera

Pinto, Luisa; Munizaga, Francisco; Le Roux, J. P.; Maksaev Jurchuc, Víctor; Zentilli, Marcos; Encinas, Alfonso
Fonte: PERGAMON-ELSEVIER SCIENCE LTD Publicador: PERGAMON-ELSEVIER SCIENCE LTD
Tipo: Artículo de revista
EN
Relevância na Pesquisa
26.66%
Lahar deposits occur within a shallow marine sedimentary succession of the Pliocene La Cueva Formation in the Coastal Cordillera of central Chile (33 degrees 40'-34 degrees 15'S). Provenance studies of the abundant volcanic material in the lahar deposits suggest that they derive from denudation by mass wasting of Oligocene-Miocene volcanic rocks on the western slopes of the Main Andean Cordillera at the same latitude. Pliocene rock debris deposits preserved in the region of El Teniente (similar to 34 degrees S) and scattered along the westernmost part of the Andes of central Chile indicate catastrophic erosive events related to the rapid uplift of the cordilleran block. This rock debris was deposited by avalanches and transformed further downslope into lahars by dilution with stream water. Lahars were channeled along the ancient drainage system that reached a shallow Pliocene sea at the site of the present Coastal Cordillera. The exceedingly rapid exhumation of active porphyry systems during the Early Pliocene in this part of the Andes may have played a role in affecting hydrothermal processes, brecciation, and diatreme, formation at the porphyry systems of El Teniente and Rio Blanco-Los Bronces.

Post-depositional fracturing and subsidence of pumice flow deposits: Lascar Volcano, Chile

Jay, J.; Calder, E. S.; Pavez, A.; Cassidy, N. J.; Pritchard, M. E.; Alcaraz, S.; Whelley, Patrick L.
Fonte: Springer Publicador: Springer
Tipo: Artículo de revista
EN
Relevância na Pesquisa
26.66%
Unconsolidated pyroclastic flow deposits of the 1993 eruption of Lascar Volcano, Chile, have, with time, become increasingly dissected by a network of deeply penetrating fractures. The fracture network comprises orthogonal sets of decimeter-wide linear voids that form a pseudo-polygonal grid visible on the deposit surface. In this work, we combine shallow surface geophysical imaging tools with remote sensing observations and direct field measurements of the deposit to investigate these fractures and their underlying causal mechanisms. Based on ground penetrating radar images, the fractures are observed to have propagated to depths of up to 10 m. In addition, orbiting radar interferometry shows that deposit subsidence of up to 1 cm/year occurred between 1993 and 1996 with continued subsidence occurring at a slower rate thereafter. In situ measurements show that 1 m below the surface, the 1993 deposits remain 5°C to 15°C hotter, 18 years after emplacement, than adjacent deposits. Based on the observed subsidence as well as estimated cooling rates, the fractures are inferred to be the combined result of deaeration, thermal contraction, and sedimentary compaction in the months to years following deposition. Significant environmental factors...

In Vivo Detection of Amyloid-\(\beta\) Deposits Using Heavy Chain Antibody Fragments in a Transgenic Mouse Model for Alzheimer's Disease

Nabuurs, Rob J. A.; Rutgers, Kim S.; Welling, Mick M.; Metaxas, Athanasios; de Backer, Maaike E.; Rotman, Maarten; van Buchem, Mark A.; van der Maarel, Silvère M.; van der Weerd, Louise; Bacskai, Brian
Fonte: Public Library of Science Publicador: Public Library of Science
Tipo: Artigo de Revista Científica
EN_US
Relevância na Pesquisa
26.66%
This study investigated the in vivo properties of two heavy chain antibody fragments (V\(_H\)H), ni3A and pa2H, to differentially detect vascular or parenchymal amyloid-\(\beta\) deposits characteristic for Alzheimer's disease and cerebral amyloid angiopathy. Blood clearance and biodistribution including brain uptake were assessed by bolus injection of radiolabeled (V\(_H\)H) in APP/PS1 mice or wildtype littermates. In addition, in vivo specificity for A\(\beta\) was examined in more detail with fluorescently labeled (V\(_H\)H) by circumventing the blood-brain barrier via direct application or intracarotid co-injection with mannitol. All (V\(_H\)H) showed rapid renal clearance (10–20 min). Twenty-four hours post-injection \(^{99m}\)Tc-pa2H resulted in a small yet significant higher cerebral uptake in the APP/PS1 animals. No difference in brain uptake were observed for \(^{99m}\)Tc-ni3A or DTPA(\(^{111}\)In)-pa2H, which lacked additional peptide tags to investigate further clinical applicability. In vivo specificity for A\(\beta\) was confirmed for both fluorescently labeled VHH, where pa2H remained readily detectable for 24 hours or more after injection. Furthermore, both VHH showed affinity for parenchymal and vascular deposits...

Orientational order in Deposits of Magnetic Particles

Tavares, J. M.; Tasinkevych, M.; Santos, F. de los; da Gama, M. M. Telo
Fonte: Universidade Cornell Publicador: Universidade Cornell
Tipo: Artigo de Revista Científica
Publicado em 06/11/2002
Relevância na Pesquisa
26.66%
We present preliminary results for the orientational order in deposits of dipolar particles, on one dimensional substrates. The deposits are generated using a model where the incoming dipolar particle interacts with the other particles in the deposit via a dipole-dipole potential. The interdipolar vectors are restricted to lie on a square lattice although the dipole moments are free to rotate in three dimensions. The path of the incoming particle is generated through a Monte Carlo scheme controlled by an effective temperature T, the case of pure diffusion-limited deposition corresponding to T=infinity$. We calculate the ferromagnetic and nematic order parameters and the dipolar orientational probability density of the deposits, at various stages of growth and two effective temperatures. The dipolar angular correlations along the rows and columns of the lattice are also investigated. We find that the orientational order of the deposits depends strongly on the lattice structure, the stage of growth and the effective temperature.; Comment: 18 pages, 6 figures